AT362381B - Verfahren zur herstellung von neuen 2,4-diamino -pyrimidinderivaten und von deren alkalimetall- salzen - Google Patents

Verfahren zur herstellung von neuen 2,4-diamino -pyrimidinderivaten und von deren alkalimetall- salzen

Info

Publication number
AT362381B
AT362381B AT496978A AT496978A AT362381B AT 362381 B AT362381 B AT 362381B AT 496978 A AT496978 A AT 496978A AT 496978 A AT496978 A AT 496978A AT 362381 B AT362381 B AT 362381B
Authority
AT
Austria
Prior art keywords
diamino
metal salts
alkaline metal
pyrimidine derivatives
producing new
Prior art date
Application number
AT496978A
Other languages
English (en)
Other versions
ATA496978A (de
Original Assignee
Dick Pierre R G
Rombi Max Andre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dick Pierre R G, Rombi Max Andre filed Critical Dick Pierre R G
Publication of ATA496978A publication Critical patent/ATA496978A/de
Application granted granted Critical
Publication of AT362381B publication Critical patent/AT362381B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT496978A 1977-07-11 1978-07-10 Verfahren zur herstellung von neuen 2,4-diamino -pyrimidinderivaten und von deren alkalimetall- salzen AT362381B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7722323A FR2397407A2 (fr) 1977-07-11 1977-07-11 Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides

Publications (2)

Publication Number Publication Date
ATA496978A ATA496978A (de) 1980-10-15
AT362381B true AT362381B (de) 1981-05-11

Family

ID=9193583

Family Applications (1)

Application Number Title Priority Date Filing Date
AT496978A AT362381B (de) 1977-07-11 1978-07-10 Verfahren zur herstellung von neuen 2,4-diamino -pyrimidinderivaten und von deren alkalimetall- salzen

Country Status (13)

Country Link
US (1) US4232023A (de)
JP (1) JPS5448776A (de)
AT (1) AT362381B (de)
AU (1) AU3793378A (de)
BE (1) BE868893A (de)
DE (1) DE2829820A1 (de)
FR (1) FR2397407A2 (de)
GB (1) GB2001965B (de)
IE (1) IE47232B1 (de)
IT (1) IT1096690B (de)
LU (1) LU79949A1 (de)
NL (1) NL7807440A (de)
ZA (1) ZA783957B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2502152A1 (fr) * 1981-03-20 1982-09-24 Panmedica Laboratoires Nouveaux derives solubles n2 substitues de la diamino-2,4-benzyl-5-pyrimidines, leur procede de preparation et medicaments les contenant
US6583148B1 (en) 1999-04-08 2003-06-24 Krenitsky Pharmaceuticals, Inc. Neurotrophic substituted pyrimidines
EP1303495B1 (de) 2000-07-24 2010-05-26 Krenitsky Pharmaceuticals, Inc. Substituierte 5-alkinyl-pyrimidine mit neurotropher wirkung
DK1725540T5 (da) 2004-03-05 2012-10-22 Hoffmann La Roche Diaminopyrimidiner som p2x3- og p2x2/3-antagonister
EP1924566B1 (de) * 2005-09-01 2016-01-13 F.Hoffmann-La Roche Ag Diaminopyrimidine als p2x3- und p3x2/3-modulatoren
CA2619919C (en) * 2005-09-01 2014-04-01 F. Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators
CN101253159B (zh) * 2005-09-01 2011-12-07 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3调节剂的二氨基嘧啶类化合物
CN101820879B (zh) * 2007-10-08 2013-01-02 疟疾药物投资公司 具有柔性侧链的抗疟用化合物
US9000003B2 (en) * 2011-03-10 2015-04-07 National Science And Technology Development Agency Anti-folate antimalarials with dual-binding modes and their preparation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2287071A (en) * 1938-08-08 1942-06-23 Parke Davis & Co Organic amine derivatives and method of obtaining same
US2374791A (en) * 1942-06-22 1945-05-01 Parke Davis & Co Organic amine derivatives and method of obtaining same
US3111521A (en) * 1962-04-25 1963-11-19 Parke Davis & Co 2-aryl-nu-(polyamino-5-pyrimidinyl)-glycinonitriles
GB1375162A (de) * 1970-10-22 1974-11-27
BE791627A (fr) * 1971-11-20 1973-05-21 Knapsack Ag Procede pour l'oxydation du monoxyde de carbone et des hydrocarbures

Also Published As

Publication number Publication date
AU3793378A (en) 1980-01-17
IE781377L (en) 1979-01-11
US4232023A (en) 1980-11-04
BE868893A (fr) 1979-01-11
ZA783957B (en) 1979-09-26
ATA496978A (de) 1980-10-15
GB2001965A (en) 1979-02-14
IT7825569A0 (it) 1978-07-11
JPS5448776A (en) 1979-04-17
IT1096690B (it) 1985-08-26
GB2001965B (en) 1982-03-10
FR2397407A2 (fr) 1979-02-09
IE47232B1 (en) 1984-01-25
LU79949A1 (fr) 1979-04-09
DE2829820A1 (de) 1979-02-01
FR2397407B2 (de) 1980-01-04
NL7807440A (nl) 1979-01-15

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