AR247723A1 - Nuevo procedimiento para preparar acido 4-amino-5-hexenoico y nuevo compuesto intermedio producido por este procedimento - Google Patents
Nuevo procedimiento para preparar acido 4-amino-5-hexenoico y nuevo compuesto intermedio producido por este procedimentoInfo
- Publication number
- AR247723A1 AR247723A1 AR92323844A AR32384492A AR247723A1 AR 247723 A1 AR247723 A1 AR 247723A1 AR 92323844 A AR92323844 A AR 92323844A AR 32384492 A AR32384492 A AR 32384492A AR 247723 A1 AR247723 A1 AR 247723A1
- Authority
- AR
- Argentina
- Prior art keywords
- procedure
- new
- amino
- preparing
- hexenoate
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 125000001495 ethyl group Chemical class [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NIONDZDPPYHYKY-UHFFFAOYSA-N 2-hexenoic acid Chemical compound CCCC=CC(O)=O NIONDZDPPYHYKY-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- BDAGIHXWWSANSR-UHFFFAOYSA-M Formate Chemical compound [O-]C=O BDAGIHXWWSANSR-UHFFFAOYSA-M 0.000 abstract 1
- -1 HYDROXY-4-HEXENOATE ETHYL Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- PJDFLNIOAUIZSL-UHFFFAOYSA-N vigabatrin Chemical compound C=CC(N)CCC(O)=O PJDFLNIOAUIZSL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/20—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
- C07C211/24—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
- C07C227/20—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters by hydrolysis of N-acylated amino-acids or derivatives thereof, e.g. hydrolysis of carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/04—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers
- C07C257/06—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers having carbon atoms of imino-carboxyl groups bound to hydrogen atoms, to acyclic carbon atoms, or to carbon atoms of rings other than six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR ACIDO 4-AMINO-5-HEXENOICO O SUS SALES FARMACEUTICAMENTE ACEPTABLES, QUE COMPRENDE LAS ETAPAS DE: (A) TRASPONER TERMICAMENTE ERITRITOL A 4-FORMILOXI-3-HIDROXI-1-BUTENO, (B) TRASPONER TERMICAMENTE 4-FORMILOXI-3-HIDROXI-1-BUTENO A 6-FORMILOXI-4-HEXENOATO DE ETILO Y SEGUIDAMENTE CONVERTIR EL FORMIATO EN SU CORRESPONDIENTE ALCOHOL, 6 HIDROXI-4-HEXENOATO DE ETILO, (C) CONVERTIR EL 6-HIDROXI-4-HEXENOATO DE ETILO ASI OBTENIDO EN 6-TRICLOROACETIMIDOXI-4-HEXENOATO DE ETILO POR REACCION CON TRICLOROACETONITRILO Y SEGUIDAMENTE TRASPONERLO TERMICAMENTE A 4-TRICLOROACETAMIDO-5-HEXENOATO DE ETILO, QUE POR HIDROLISIS SE CONVIERTE EN EL ACIDO 4-AMINO-5-HEXENOICO DESEADO Y OPCIONALMENTE CONVERTIR DICHO ACIDO EN UNA DE SUS SALES FARMACEUTICAMENTE ACEPTABLES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP91403351A EP0546230A1 (en) | 1991-12-10 | 1991-12-10 | Novel process for preparing 4-amino-5-hexenoic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
AR247723A1 true AR247723A1 (es) | 1995-03-31 |
Family
ID=8208648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR92323844A AR247723A1 (es) | 1991-12-10 | 1992-12-09 | Nuevo procedimiento para preparar acido 4-amino-5-hexenoico y nuevo compuesto intermedio producido por este procedimento |
Country Status (19)
Country | Link |
---|---|
US (4) | US5380936A (es) |
EP (3) | EP0546230A1 (es) |
JP (1) | JP3229408B2 (es) |
KR (2) | KR100248550B1 (es) |
AR (1) | AR247723A1 (es) |
AT (2) | ATE151070T1 (es) |
AU (1) | AU658699B2 (es) |
CA (1) | CA2084109C (es) |
DE (2) | DE69218736T2 (es) |
DK (2) | DK0718273T3 (es) |
ES (2) | ES2102482T3 (es) |
FI (1) | FI114632B (es) |
GR (2) | GR3023608T3 (es) |
HU (2) | HU9203897D0 (es) |
IL (5) | IL116968A (es) |
NO (1) | NO300731B1 (es) |
NZ (1) | NZ245398A (es) |
TW (1) | TW224086B (es) |
ZA (1) | ZA929443B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009046452A (ja) | 2007-08-22 | 2009-03-05 | Erick M Carreira | ホスホルアミダイト配位子およびそれを用いたアリルアミンの製造方法 |
WO2010101957A1 (en) * | 2009-03-02 | 2010-09-10 | Wordlock, Inc. | Combination lock assemblies and methods for marking combination lock assemblies including distributions of consonants and vowels |
WO2010101952A1 (en) * | 2009-03-02 | 2010-09-10 | Wordlock, Inc. | Combination lock assemblies and methods for making combination lock assemblies including random selection of characters |
EP2537827B1 (en) | 2011-06-24 | 2014-06-11 | Targeon SAS | Process for preparing 4-amino-5-hexenoic acid from succinimide |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US31980A (en) * | 1861-04-09 | Duane hull | ||
US3879448A (en) * | 1970-02-07 | 1975-04-22 | Takeda Chemical Industries Ltd | 4-hexenoic compounds |
FR2085653B1 (es) * | 1970-04-30 | 1973-06-08 | Roussel Uclaf | |
US4039549A (en) * | 1975-03-18 | 1977-08-02 | Merrell Toraude Et Compagnie | Olefinic derivatives of amino acids |
USRE31980E (en) * | 1975-03-18 | 1985-09-03 | Merrell Toraude Et Compagnie | Olefinic derivatives of amino acids |
US3960927A (en) * | 1975-03-18 | 1976-06-01 | Richardson-Merrell Inc. | Olefinic derivatives of amino acids |
US4178463A (en) * | 1978-01-30 | 1979-12-11 | Merrell Toraude Et Compagnie | Process for making 4-aminohex-5-enoic acid |
US4672140A (en) * | 1981-01-02 | 1987-06-09 | Monsanto Company | Acyloxyalkenoic acids and process therefor |
US4692538A (en) * | 1982-04-14 | 1987-09-08 | Bristol-Myers Company | Trichloroethanimidic acid esters |
GB2133002B (en) * | 1982-12-30 | 1986-01-29 | Merrell Toraude & Co | Process for preparing 4-amino-5-hexenoic acid |
US4912232A (en) * | 1983-10-14 | 1990-03-27 | Dow Chemical Company | Preparation of N-hydrocarbylcarbonyl-5-(1-hydrocarbylcarbonyloxy)hydrocarbyl-pyrrolidin-2-one |
DE3568771D1 (en) * | 1984-10-10 | 1989-04-20 | Givaudan & Cie Sa | Hexanoates, process for their preparation and perfumes and/or flavouring agents having a content of such compounds |
ES2053582T3 (es) * | 1986-08-13 | 1994-08-01 | Ciba Geigy Ag | Procedimiento para la obtencion de derivados del acido 5-amino-4-hidroxivalerianico. |
YU48319B (sh) * | 1988-08-01 | 1998-05-15 | Monsanto Company | Bezbednosni herbicidni derivati benzoeve kiseline |
AU629419B2 (en) * | 1989-11-07 | 1992-10-01 | Aventis Inc. | Process for the production of vinyl-gaba |
DE4010709A1 (de) * | 1990-04-03 | 1991-10-10 | Huels Chemische Werke Ag | Verfahren zur herstellung von 3-carboxamido-5-vinyl-2-pyrrolidon |
JPH0692903A (ja) * | 1992-09-09 | 1994-04-05 | Yuki Gosei Kogyo Co Ltd | 5−ホルミルオキシ−3−ペンテン酸またはそのエステルおよびその製造法 |
-
1991
- 1991-12-10 EP EP91403351A patent/EP0546230A1/en not_active Withdrawn
-
1992
- 1992-11-30 CA CA002084109A patent/CA2084109C/en not_active Expired - Lifetime
- 1992-12-04 AU AU29886/92A patent/AU658699B2/en not_active Expired
- 1992-12-04 ZA ZA929443A patent/ZA929443B/xx unknown
- 1992-12-07 EP EP96200414A patent/EP0718273B1/en not_active Expired - Lifetime
- 1992-12-07 IL IL11696892A patent/IL116968A/en not_active IP Right Cessation
- 1992-12-07 DE DE69218736T patent/DE69218736T2/de not_active Expired - Lifetime
- 1992-12-07 DK DK96200414.9T patent/DK0718273T3/da active
- 1992-12-07 ES ES92403296T patent/ES2102482T3/es not_active Expired - Lifetime
- 1992-12-07 IL IL104013A patent/IL104013A/xx not_active IP Right Cessation
- 1992-12-07 ES ES96200414T patent/ES2116130T3/es not_active Expired - Lifetime
- 1992-12-07 AT AT92403296T patent/ATE151070T1/de active
- 1992-12-07 EP EP92403296A patent/EP0546906B1/en not_active Expired - Lifetime
- 1992-12-07 DK DK92403296.4T patent/DK0546906T3/da active
- 1992-12-07 IL IL11696896A patent/IL116968A0/xx unknown
- 1992-12-07 IL IL11696792A patent/IL116967A/xx not_active IP Right Cessation
- 1992-12-07 TW TW081109783A patent/TW224086B/zh not_active IP Right Cessation
- 1992-12-07 DE DE69224760T patent/DE69224760T2/de not_active Expired - Lifetime
- 1992-12-07 JP JP35107892A patent/JP3229408B2/ja not_active Expired - Lifetime
- 1992-12-07 AT AT96200414T patent/ATE163916T1/de active
- 1992-12-08 KR KR1019920023550A patent/KR100248550B1/ko not_active IP Right Cessation
- 1992-12-08 NZ NZ24539892A patent/NZ245398A/en unknown
- 1992-12-09 NO NO924763A patent/NO300731B1/no not_active IP Right Cessation
- 1992-12-09 HU HU9203897A patent/HU9203897D0/hu unknown
- 1992-12-09 FI FI925592A patent/FI114632B/fi not_active IP Right Cessation
- 1992-12-09 HU HU9203897A patent/HU213374B/hu unknown
- 1992-12-09 AR AR92323844A patent/AR247723A1/es active
-
1994
- 1994-01-19 US US08/184,762 patent/US5380936A/en not_active Expired - Lifetime
- 1994-07-22 US US08/279,620 patent/US5440065A/en not_active Expired - Lifetime
-
1995
- 1995-04-11 US US08/420,179 patent/US5512698A/en not_active Expired - Fee Related
- 1995-04-11 US US08/420,178 patent/US5473099A/en not_active Expired - Fee Related
-
1996
- 1996-01-30 IL IL11696796A patent/IL116967A0/xx unknown
-
1997
- 1997-05-30 GR GR970401252T patent/GR3023608T3/el unknown
-
1998
- 1998-04-03 GR GR980400706T patent/GR3026522T3/el unknown
-
1999
- 1999-08-30 KR KR1019990036254A patent/KR100249593B1/ko not_active IP Right Cessation
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