AR230281A1 - PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLIDINE-2,4-DIONA-5-SUBSTITUTED - Google Patents

PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLIDINE-2,4-DIONA-5-SUBSTITUTED

Info

Publication number: AR230281A1
Authority: AR; Argentina
Prior art keywords: diona; oxazolidine; racemic; substituted; procedure
Prior art date: 1980-07-28

Application number

AR289216A

Other languages

Spanish (es)

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-07-28

Filing date

1982-04-27

Publication date

1984-03-01

1981-01-02 Priority claimed from US06/222,202 external-priority patent/US4367234A/en

1981-04-23 Priority claimed from US06/252,961 external-priority patent/US4332952A/en

1981-04-23 Priority claimed from US06/252,962 external-priority patent/US4342771A/en

1982-04-27 Application filed by Pfizer filed Critical Pfizer

1984-03-01 Application granted granted Critical

1984-03-01 Publication of AR230281A1 publication Critical patent/AR230281A1/en

Links

150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AR289216A 1980-07-28 1982-04-27 PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLIDINE-2,4-DIONA-5-SUBSTITUTED AR230281A1 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US17320680A	1980-07-28	1980-07-28
US06/222,202 US4367234A (en)	1980-07-28	1981-01-02	Hypoglycemic 5-substituted oxazolidine-2,4-diones
US06/252,961 US4332952A (en)	1980-07-28	1981-04-23	Hypoglycemic 5-substituted oxazolidine-2,4-diones
US06/252,962 US4342771A (en)	1981-01-02	1981-04-23	Hypoglycemic 5-substituted oxazolidine-2,4-diones

Publications (1)

Publication Number	Publication Date
AR230281A1 true AR230281A1 (en)	1984-03-01

Family

ID=27497044

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AR289216A AR230281A1 (en)	1980-07-28	1982-04-27	PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLIDINE-2,4-DIONA-5-SUBSTITUTED
AR289218A AR230053A1 (en)	1980-07-28	1982-04-27	A PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLIDINE-2.4-DIONA 5-SUBSTITUTED AND INTERMEDIATE COMPOUND FOR THE SAME
AR289217A AR229958A1 (en)	1980-07-28	1982-04-27	A PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLYCIN-2,4-DIONA 5-SUBSTITUTED INTERMEDIATE COMPOUND FOR THE SAME AND PROCEDURE FOR PREPARING STARTING COMPOUNDS FOR SUCH PROCEDURE

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AR289218A AR230053A1 (en)	1980-07-28	1982-04-27	A PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLIDINE-2.4-DIONA 5-SUBSTITUTED AND INTERMEDIATE COMPOUND FOR THE SAME
AR289217A AR229958A1 (en)	1980-07-28	1982-04-27	A PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLYCIN-2,4-DIONA 5-SUBSTITUTED INTERMEDIATE COMPOUND FOR THE SAME AND PROCEDURE FOR PREPARING STARTING COMPOUNDS FOR SUCH PROCEDURE

Country Status (29)

Country	Link
JP (1)	JPS5764692A (en)
AR (3)	AR230281A1 (en)
AU (2)	AU526733B2 (en)
CA (1)	CA1161843A (en)
CH (1)	CH653029A5 (en)
CS (1)	CS237320B2 (en)
DD (1)	DD202555A5 (en)
DE (1)	DE3129275A1 (en)
DK (1)	DK152650C (en)
ES (4)	ES504321A0 (en)
FI (1)	FI75820C (en)
FR (1)	FR2487350B1 (en)
GB (5)	GB2080803B (en)
GR (1)	GR75303B (en)
HK (1)	HK43886A (en)
IE (1)	IE51662B1 (en)
IL (1)	IL63424A (en)
IT (1)	IT1138111B (en)
KE (1)	KE3624A (en)
LU (1)	LU83513A1 (en)
MY (1)	MY8600596A (en)
NO (1)	NO812559L (en)
NZ (1)	NZ197854A (en)
PH (2)	PH21172A (en)
PL (1)	PL133220B1 (en)
PT (1)	PT73436B (en)
SE (1)	SE461039B (en)
SG (1)	SG56656G (en)
YU (2)	YU185481A (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4695634A (en) *	1981-01-02	1987-09-22	Pfizer Inc.	Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4689336A (en) *	1981-01-02	1987-08-25	Pfizer Inc.	Hypoglycemic 5-substituted oxazolidine 2,4-diones
GR78120B (en) *	1982-03-01	1984-09-26	Pfizer
DE3233089A1 (en) *	1982-09-07	1984-03-08	Basf Ag, 6700 Ludwigshafen	CHINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR CONTROLLING UNWANTED PLANT GROWTH
JPS59152382A (en) *	1983-02-18	1984-08-31	Tanabe Seiyaku Co Ltd	Furyloxazolylacetic acid derivative and its preparation
HU203330B (en) *	1987-06-10	1991-07-29	Pfizer	Process for producing oxazolidin-2-one derivatives and hypoglychemic pharmaceutical compositions containing them
TW403748B (en)	1994-11-02	2000-09-01	Takeda Chemical Industries Ltd	An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same
IL117208A0 (en) *	1995-02-23	1996-06-18	Nissan Chemical Ind Ltd	Indole type thiazolidines
SI2384753T1 (en)	2003-08-29	2016-06-30	The Brigham And Women's Hospital, Inc.	Hydantoin derivatives as inhibitors of cellular necrosis
CN103450077B (en) *	2007-06-08	2016-07-06	满康德股份有限公司	IRE-1 alpha inhibitor
JP2012513481A (en)	2008-12-23	2012-06-14	プレジデントアンドフェロウズオブハーバードカレッジ	Small molecule inhibitors of necrotosis
WO2014145022A1 (en)	2013-03-15	2014-09-18	President And Fellows Of Harvard College	Hybrid necroptosis inhibitors
EP3229807A4 (en)	2014-12-11	2018-10-17	President and Fellows of Harvard College	Inhibitors of cellular necrosis and related methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE729852C (en) *	1939-07-06	1943-01-04	Carl Nachtigall	Process for the preparation of 2,4-dioxooxazolidines
DE834992C (en) *	1946-09-16	1952-03-27	British Schering Res Lab Ltd	Process for the preparation of N-alkyl or N-aralkyl derivatives of oxazolidine-2, 4-dynes
US2721197A (en) *	1953-01-05	1955-10-18	Bristol Lab Inc	Bicyclic lactams
US2954381A (en) *	1958-12-03	1960-09-27	Us Vitamin Pharm Corp	Heteroaryloxazolidinediones
US3699229A (en) *	1970-12-18	1972-10-17	Abbott Lab	2-oxo-5-phenyl-4-oxazolidinone as an anti-depressant agent
DE2813873A1 (en) *	1978-03-31	1979-10-11	Basf Ag	PROCESS FOR THE PRODUCTION OF OXAZOLIDINE-2,4-DIONEN
US4200642A (en) *	1978-08-21	1980-04-29	Pfizer Inc.	Spiro-oxazolidindiones

1981
- 1981-07-22 SG SG305/86A patent/SG56656G/en unknown
- 1981-07-22 GB GB8122524A patent/GB2080803B/en not_active Expired
- 1981-07-23 PL PL1981232330A patent/PL133220B1/en unknown
- 1981-07-23 CS CS815646A patent/CS237320B2/en unknown
- 1981-07-24 SE SE8104543A patent/SE461039B/en not_active IP Right Cessation
- 1981-07-24 DE DE19813129275 patent/DE3129275A1/en active Granted
- 1981-07-27 DD DD81232129A patent/DD202555A5/en unknown
- 1981-07-27 CA CA000382568A patent/CA1161843A/en not_active Expired
- 1981-07-27 GR GR65638A patent/GR75303B/el unknown
- 1981-07-27 IE IE1696/81A patent/IE51662B1/en unknown
- 1981-07-27 AU AU73436/81A patent/AU526733B2/en not_active Ceased
- 1981-07-27 PT PT73436A patent/PT73436B/en unknown
- 1981-07-27 YU YU01854/81A patent/YU185481A/en unknown
- 1981-07-27 FR FR8114542A patent/FR2487350B1/en not_active Expired
- 1981-07-27 NO NO812559A patent/NO812559L/en unknown
- 1981-07-27 IT IT23176/81A patent/IT1138111B/en active
- 1981-07-27 FI FI812339A patent/FI75820C/en not_active IP Right Cessation
- 1981-07-27 IL IL63424A patent/IL63424A/en unknown
- 1981-07-27 NZ NZ197854A patent/NZ197854A/en unknown
- 1981-07-27 PH PH25966A patent/PH21172A/en unknown
- 1981-07-27 ES ES504321A patent/ES504321A0/en active Granted
- 1981-07-27 CH CH4878/81A patent/CH653029A5/en not_active IP Right Cessation
- 1981-07-27 DK DK334781A patent/DK152650C/en not_active IP Right Cessation
- 1981-07-27 LU LU83513A patent/LU83513A1/en unknown
- 1981-07-27 JP JP56117572A patent/JPS5764692A/en active Granted
1982
- 1982-04-27 AR AR289216A patent/AR230281A1/en active
- 1982-04-27 AR AR289218A patent/AR230053A1/en active
- 1982-04-27 AR AR289217A patent/AR229958A1/en active
- 1982-07-23 ES ES514316A patent/ES8305760A1/en not_active Expired
- 1982-07-23 ES ES514315A patent/ES514315A0/en active Granted
- 1982-07-23 ES ES514314A patent/ES514314A0/en active Granted
- 1982-11-02 AU AU90100/82A patent/AU548932B2/en not_active Ceased
1983
- 1983-01-03 PH PH28343A patent/PH18925A/en unknown
- 1983-04-22 YU YU00919/83A patent/YU91983A/en unknown
- 1983-06-24 GB GB08317147A patent/GB2128184B/en not_active Expired
- 1983-06-24 GB GB08317142A patent/GB2134104B/en not_active Expired
- 1983-06-24 GB GB08317146A patent/GB2131422B/en not_active Expired
- 1983-06-24 GB GB08317143A patent/GB2134105B/en not_active Expired
1986
- 1986-04-04 KE KE3624A patent/KE3624A/en unknown
- 1986-06-09 HK HK438/86A patent/HK43886A/en unknown
- 1986-12-30 MY MY596/86A patent/MY8600596A/en unknown

Also Published As

Publication number	Publication date
AU9010082A (en)	1983-03-03
ES8301976A1 (en)	1983-01-01
GB2080803A (en)	1982-02-10
DE3129275C2 (en)	1987-10-15
ES8306147A1 (en)	1983-05-01
IL63424A0 (en)	1981-10-30
GB8317143D0 (en)	1983-07-27
HK43886A (en)	1986-06-20
AU548932B2 (en)	1986-01-09
GR75303B (en)	1984-07-13
GB2134104A (en)	1984-08-08
DD202555A5 (en)	1983-09-21
FR2487350A1 (en)	1982-01-29
ES514316A0 (en)	1983-04-16
AR230053A1 (en)	1984-02-29
DK334781A (en)	1982-02-25
IE51662B1 (en)	1987-02-04
CS564681A2 (en)	1984-12-14
CS237320B2 (en)	1985-07-16
DK152650C (en)	1988-08-29
CA1161843A (en)	1984-02-07
IT8123176A0 (en)	1981-07-27
ES514314A0 (en)	1983-05-01
IL63424A (en)	1985-09-29
ES8306148A1 (en)	1983-05-01
JPS5764692A (en)	1982-04-19
SE461039B (en)	1989-12-18
AU526733B2 (en)	1983-01-27
AU7343681A (en)	1982-02-04
GB2134105B (en)	1985-01-16
GB2131422A (en)	1984-06-20
PT73436A (en)	1981-08-01
KE3624A (en)	1986-05-16
YU91983A (en)	1983-10-31
JPS6335632B2 (en)	1988-07-15
CH653029A5 (en)	1985-12-13
AR229958A1 (en)	1984-01-31
FI75820B (en)	1988-04-29
GB2128184A (en)	1984-04-26
GB2131422B (en)	1984-12-05
PL133220B1 (en)	1985-05-31
PL232330A1 (en)	1983-09-26
ES8305760A1 (en)	1983-04-16
GB2134105A (en)	1984-08-08
PH21172A (en)	1987-08-07
GB8317146D0 (en)	1983-07-27
IT1138111B (en)	1986-09-17
GB2080803B (en)	1984-01-18
SG56656G (en)	1987-03-27
SE8104543L (en)	1982-01-29
IE811696L (en)	1982-01-28
GB2134104B (en)	1985-02-06
ES514315A0 (en)	1983-05-01
PT73436B (en)	1983-09-01
GB8317142D0 (en)	1983-07-27
NO812559L (en)	1982-01-29
ES504321A0 (en)	1983-01-01
FI812339L (en)	1982-01-29
MY8600596A (en)	1986-12-31
GB2128184B (en)	1984-08-15
DE3129275A1 (en)	1982-04-22
GB8317147D0 (en)	1983-07-27
FR2487350B1 (en)	1986-04-04
FI75820C (en)	1988-08-08
LU83513A1 (en)	1982-02-17
PH18925A (en)	1985-11-11
NZ197854A (en)	1984-11-09
DK152650B (en)	1988-04-05
YU185481A (en)	1983-10-31

Publication	Publication Date	Title
AR230834A1 (en)	1984-07-31	A PROCEDURE FOR THE PREPARATION OF OXAZOLIDIN-2,4-DIONAS 5-SUBSTITUTED HIPLOGICEMICAS
ES504905A0 (en)	1983-02-01	A PROCEDURE FOR THE PREPARATION OF A NEW BACAMPICILIN FORMULATION.
ES499565A0 (en)	1982-08-16	A PROCEDURE FOR THE PREPARATION OF FLUORINE COPOLYMERS.
ES506969A0 (en)	1983-07-01	A PROCEDURE FOR THE PREPARATION OF PIRIMIDINAS SUBSTITUTES-IDAS.
ES501645A0 (en)	1983-02-01	A PROCEDURE FOR THE PREPARATION OF 6-ALQUILIDEN-PENAMAS.
ES505464A0 (en)	1983-01-01	A PROCEDURE FOR THE PREPARATION OF N-HETEROCICLILAMINOCARBONIL ARILSULFONAMIDAS.
ES506992A0 (en)	1984-06-01	A PROCEDURE FOR THE PREPARATION OF A MACROLIADA.
ES511079A0 (en)	1983-03-16	A PROCEDURE FOR THE PREPARATION OF A N- (2-PIRIMIDINYL) PIPERAZINYLALKYLAZAESPIROALCANODIONA.
AR225794A1 (en)	1982-04-30	A PROCEDURE FOR THE PREPARATION OF 2- (2- (1,4-BENZODIOXANIL)) - 2-IMIDAZOLINE
AR230281A1 (en)	1984-03-01	PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLIDINE-2,4-DIONA-5-SUBSTITUTED
ES507506A0 (en)	1982-09-01	A PROCEDURE FOR THE PREPARATION OF IMIDAZOLYLPHENYLAMI-DINAS.
ES503307A0 (en)	1983-02-01	A PROCEDURE FOR THE PREPARATION OF QUINOXALINYLOXIETERS.
ES506216A0 (en)	1982-12-16	A PROCEDURE FOR THE PREPARATION OF 2-GUANIDINO-4-HETEROARIL-TIAZOLES.
ES503878A0 (en)	1982-11-01	A PROCEDURE FOR THE PREPARATION OF A CIS-4,5-DISSTITUTED DERIVATIVE OF OPTIMALLY ACTIVE IMIDAZOLIDIN-2-ONA.
ES506281A0 (en)	1982-12-01	A PROCEDURE FOR THE PREPARATION OF 4- (4-IMIDAZOLIL) 2-SUBSTITUTED PIRIDINES.
ES502153A0 (en)	1982-08-16	A PROCEDURE FOR THE PREPARATION OF COMPOUNDS N-ACIL-N- (CICLOALQUIL) AMINOACIDOS.
ES507919A0 (en)	1983-01-16	A PROCEDURE FOR THE PREPARATION OF ANTIALERGIC BENZOPYRANOTRIAZOLES.
ES492844A0 (en)	1981-11-01	A PROCEDURE FOR THE PREPARATION OF AN OPTICALLY ACTIVE ARYLOXIAL-NOIC COMPOUND
ES514335A0 (en)	1983-04-16	A PROCEDURE FOR THE PREPARATION OF GUANIDINAS.
ES506034A0 (en)	1983-01-01	A PROCEDURE FOR THE PREPARATION OF N-CARBOXIALKYL-DIPEPTIDES.
ES523685A0 (en)	1984-11-16	A PROCEDURE FOR PREPARING RACEMICALLY OPTICALLY ACTIVE EBURNANO-OXIMA ETER DERIVATIVES.
AR230445A1 (en)	1984-04-30	A PROCEDURE FOR THE PREPARATION OF A RACEMIC OR OPTICALLY ACTIVE COMPOUND OF OXAZOLIDINE-2,4-DIONA 5-SUBSTITUTED AND INTERMEDIATE COMPOUNDS USED
ES502364A0 (en)	1982-10-01	A PROCEDURE FOR THE PREPARATION OF NEW CAGE HETEROTRICICLIC DERIVATIVES.
ES523684A0 (en)	1985-10-01	A PROCEDURE FOR PREPARING RACEMICALLY OR OPTICALLY ACTIVE EBURNANO DERIVATIVES.
ES498357A0 (en)	1982-09-01	A PROCEDURE FOR THE PREPARATION OF NEW POLYFLUORETOXIBENENAMINES.