AR208769A1 - Un procedimiento para preparar nuevos derivados de la 3-sulfonamido-piridina - Google Patents
Un procedimiento para preparar nuevos derivados de la 3-sulfonamido-piridinaInfo
- Publication number
- AR208769A1 AR208769A1 AR262626A AR26262676A AR208769A1 AR 208769 A1 AR208769 A1 AR 208769A1 AR 262626 A AR262626 A AR 262626A AR 26262676 A AR26262676 A AR 26262676A AR 208769 A1 AR208769 A1 AR 208769A1
- Authority
- AR
- Argentina
- Prior art keywords
- sulfonamide
- pyridine
- procedure
- new derivatives
- prepare new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C07D213/71—Sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1683674A GB1477664A (en) | 1974-04-17 | 1974-04-17 | Pyridine derivatives |
YU1507/81A YU42409B (en) | 1974-04-17 | 1981-06-15 | Process for obtaining new pyridine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
AR208769A1 true AR208769A1 (es) | 1977-02-28 |
Family
ID=26252269
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR258409A AR211097A1 (es) | 1974-04-17 | 1975-04-17 | Procedimiento para la preparacionde nuevos derivados de 3-(carbamil o tiocarbamil)-sulfamido-piridina-4-sustituida. |
AR262627A AR208770A1 (es) | 1974-04-17 | 1976-03-19 | Un procedimiento para preparar nuevos derivados de la 3(acilsulfonamido)-piridina-4-sustituida |
AR262626A AR208769A1 (es) | 1974-04-17 | 1976-03-19 | Un procedimiento para preparar nuevos derivados de la 3-sulfonamido-piridina |
AR262625A AR208768A1 (es) | 1974-04-17 | 1976-03-19 | Un procedimiento para preparar nuevos derivados de la 4-amino-3-sulfonamido-piridina |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR258409A AR211097A1 (es) | 1974-04-17 | 1975-04-17 | Procedimiento para la preparacionde nuevos derivados de 3-(carbamil o tiocarbamil)-sulfamido-piridina-4-sustituida. |
AR262627A AR208770A1 (es) | 1974-04-17 | 1976-03-19 | Un procedimiento para preparar nuevos derivados de la 3(acilsulfonamido)-piridina-4-sustituida |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR262625A AR208768A1 (es) | 1974-04-17 | 1976-03-19 | Un procedimiento para preparar nuevos derivados de la 4-amino-3-sulfonamido-piridina |
Country Status (19)
Country | Link |
---|---|
US (2) | US4018929A (es) |
JP (1) | JPS5951536B2 (es) |
AR (4) | AR211097A1 (es) |
AT (1) | AT344170B (es) |
BE (1) | BE827844A (es) |
CA (1) | CA1070313A (es) |
CH (3) | CH610890A5 (es) |
DD (2) | DD126887A5 (es) |
DE (1) | DE2516025A1 (es) |
ES (4) | ES436581A1 (es) |
FR (1) | FR2267775B1 (es) |
GB (1) | GB1477664A (es) |
HU (1) | HU171420B (es) |
IL (1) | IL47084A (es) |
LU (2) | LU72284A1 (es) |
NL (2) | NL183580C (es) |
SE (2) | SE424320B (es) |
YU (1) | YU42409B (es) |
ZA (1) | ZA752243B (es) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1593609A (en) * | 1978-01-31 | 1981-07-22 | Christiaens Sa A | Pyridine sulfonamides |
US4776878A (en) * | 1978-12-04 | 1988-10-11 | E. I. Du Pont De Nemours And Company | Agricultural pyridinesulfonamides |
LU85193A1 (fr) * | 1984-01-31 | 1985-09-12 | Christiaens Sa A | Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation |
DE3529529A1 (de) * | 1985-08-17 | 1987-02-19 | Boehringer Mannheim Gmbh | Verfahren zur herstellung einer stabilen modifikation von torasemid |
US4853389A (en) * | 1987-07-24 | 1989-08-01 | American Home Products Corporation | Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas |
US4914203A (en) * | 1987-07-24 | 1990-04-03 | American Home Products Corporation | 5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas |
FR2659080B1 (fr) * | 1990-03-02 | 1994-07-08 | Adir | Nouveaux derives de la pyridylsulfonyluree et de la pyridylsulfonylthiouree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US5166162A (en) * | 1990-03-02 | 1992-11-24 | Adir Et Compagnie | Pyridylsulfonylurea and pyridylsulfonylthiourea compounds |
US5486530A (en) * | 1991-04-27 | 1996-01-23 | Boehringer Mannheim Gmbh | Use of torasemide for the treatment of brain oedemas |
IT1288123B1 (it) * | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
HRP980532B1 (en) | 1998-10-02 | 2005-06-30 | Pliva | Novel crystalline torasemide modification |
US6166045A (en) * | 1998-06-02 | 2000-12-26 | Roche Diagnostics Gmbh | Torasemide of modification III |
US7214711B2 (en) * | 1998-12-23 | 2007-05-08 | Neurotherapeutics Pharma Llc | Method of treating migraine headache without aura |
US8008283B2 (en) * | 1998-12-23 | 2011-08-30 | Neurotherapeutics Pharma, Inc. | Methods and compositions for the treatment of neuropsychiatric disorders |
US8722668B2 (en) * | 1998-12-23 | 2014-05-13 | Daryl W. Hochman | Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders |
AU781461C (en) * | 1999-08-11 | 2006-02-23 | Teva Pharmaceutical Industries Ltd. | Torsemide polymorphs |
SI1292303T1 (en) | 2000-02-17 | 2004-10-31 | Teva Pharmaceutical Industries Ltd. | A stable pharmaceutical formulation comprising torsemide modification ii |
EP1741429A3 (en) * | 2000-03-20 | 2007-01-17 | Teva Pharmaceutical Industries Ltd. | Processes for preparing torsemide |
HRP20000162B1 (en) * | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
AU2001247592B2 (en) * | 2000-03-20 | 2005-08-18 | Teva Pharmaceutical Industries Ltd. | Novel processes for preparing torsemide intermediate |
HRP20000328A2 (en) * | 2000-05-19 | 2002-02-28 | Pliva Farmaceutska Ind Dionik | Novel polymorph v of torasemide |
US20030022921A1 (en) * | 2001-02-21 | 2003-01-30 | Minutza Leibovici | Stable pharmaceutical formulation comprising torsemide modification II |
IN192178B (es) | 2001-08-03 | 2004-03-06 | Ranbaxy Lab | |
IL149771A0 (en) * | 2002-05-21 | 2002-11-10 | Fintech Lab Ltd | Process for preparation of torsemide |
HRP20020603B1 (en) * | 2002-07-19 | 2008-11-30 | Pliva D.D. | New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide |
ES2362998T3 (es) | 2002-08-19 | 2011-07-18 | Pfizer Inc. | Terapia de combinación para enfermedades hiperproliferativas. |
CA2401546C (en) * | 2002-09-06 | 2006-09-19 | Brantford Chemicals Inc. | Preparation of derivatives of 3-sulfonamido-4-phenylaminopyridine |
ITMI20022749A1 (it) * | 2002-12-23 | 2004-06-24 | Cosma S P A | Nuovo procedimento per la sintesi della tosemide, in particolare della forma ii pura e stabile. |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
US20050215600A1 (en) * | 2003-10-27 | 2005-09-29 | Arie Gutman | Polymorphs of torsemide hydrochloride and process for production thereof |
US7378527B2 (en) * | 2004-03-16 | 2008-05-27 | Daqing Che | Process for the preparation of torsemide and related intermediates |
WO2007047447A2 (en) * | 2005-10-17 | 2007-04-26 | Neurotherapeutics Pharma, Inc. | Diuretic-like compound analogs useful for regulation of central nervous system disorders |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7625896B2 (en) * | 2005-11-25 | 2009-12-01 | Hoffman-La Roche Inc. | Pyridylsulfonamide derivatives |
US7939532B2 (en) * | 2006-10-26 | 2011-05-10 | Hoffmann-La Roche Inc. | Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents |
CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
EP2148861A1 (en) * | 2007-05-16 | 2010-02-03 | F. Hoffmann-Roche AG | Aryl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents |
NL2006622C2 (en) | 2011-04-18 | 2012-10-22 | Eurovet Animal Health B V | Use of a composition comprising torasemide. |
EP2887806B1 (en) | 2012-07-20 | 2019-11-13 | University Of Rochester | Method of treating and preventing brain impairment using na+-k+ -2ci- cotransporter isoform 1 inhibitors |
EP2986599A1 (en) | 2013-04-17 | 2016-02-24 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
MA41553B1 (fr) * | 2015-02-16 | 2020-04-30 | The Provost Fellows Found Scholars And The Other Members Of Board Of The College Of The Holy & Undiv | Sulfonylurées, composés apparentés, et leur utilisation |
DK3661925T3 (da) | 2017-07-07 | 2022-02-28 | Inflazome Ltd | Hidtil ukendte sulfonamidcarboxamidforbindelser |
CA3125765A1 (en) | 2019-01-18 | 2020-07-23 | Astrazeneca Ab | Pcsk9 inhibitors and methods of use thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3674794A (en) * | 1970-03-18 | 1972-07-04 | Ciba Geigy Corp | Certain-3-pyridine-sulfonamide derivatives |
GB1368948A (en) * | 1970-11-11 | 1974-10-02 | Manuf Prod Pharma | Pyridine derivatives |
US3904636A (en) * | 1971-11-09 | 1975-09-09 | Christiaens Sa A | 3-sulfonamido-4-phenyl aminopyridines and derivatives |
GB1414793A (en) * | 1972-07-28 | 1975-11-19 | Manuf Prod Pharma | Derivatives of phenylaminopyridine |
-
1974
- 1974-04-17 GB GB1683674A patent/GB1477664A/en not_active Expired
-
1975
- 1975-04-08 ZA ZA00752243A patent/ZA752243B/xx unknown
- 1975-04-11 BE BE155330A patent/BE827844A/xx not_active IP Right Cessation
- 1975-04-12 DE DE19752516025 patent/DE2516025A1/de active Granted
- 1975-04-14 ES ES436581A patent/ES436581A1/es not_active Expired
- 1975-04-14 HU HU75CI00001569A patent/HU171420B/hu unknown
- 1975-04-14 IL IL47084A patent/IL47084A/xx unknown
- 1975-04-15 LU LU72284A patent/LU72284A1/xx unknown
- 1975-04-16 US US05/568,759 patent/US4018929A/en not_active Expired - Lifetime
- 1975-04-16 AT AT288275A patent/AT344170B/de not_active IP Right Cessation
- 1975-04-16 SE SE7504409A patent/SE424320B/xx unknown
- 1975-04-16 CH CH216378A patent/CH610890A5/xx active Protection Beyond IP Right Term
- 1975-04-16 NL NLAANVRAGE7504521,A patent/NL183580C/xx active Protection Beyond IP Right Term
- 1975-04-16 CH CH485775A patent/CH609045A5/xx active Protection Beyond IP Right Term
- 1975-04-16 CH CH216478A patent/CH612424A5/xx not_active IP Right Cessation
- 1975-04-16 FR FR7511791A patent/FR2267775B1/fr not_active Expired
- 1975-04-16 CA CA224,805A patent/CA1070313A/en not_active Expired
- 1975-04-17 JP JP50047371A patent/JPS5951536B2/ja not_active Expired
- 1975-04-17 AR AR258409A patent/AR211097A1/es active
- 1975-04-17 DD DD194800A patent/DD126887A5/xx unknown
- 1975-04-17 DD DD185508A patent/DD121936A5/xx unknown
-
1976
- 1976-03-19 AR AR262627A patent/AR208770A1/es active
- 1976-03-19 AR AR262626A patent/AR208769A1/es active
- 1976-03-19 AR AR262625A patent/AR208768A1/es active
- 1976-11-15 ES ES453328A patent/ES453328A1/es not_active Expired
- 1976-11-15 ES ES453327A patent/ES453327A1/es not_active Expired
- 1976-11-15 ES ES453329A patent/ES453329A1/es not_active Expired
-
1979
- 1979-09-13 SE SE7907618A patent/SE7907618L/sv not_active Application Discontinuation
-
1980
- 1980-02-07 US US06/119,601 patent/USRE30633E/en not_active Expired - Lifetime
-
1981
- 1981-06-15 YU YU1507/81A patent/YU42409B/xx unknown
-
1993
- 1993-06-30 LU LU88346C patent/LU88346I2/fr unknown
-
1994
- 1994-07-27 NL NL940014C patent/NL940014I2/nl unknown
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