AR113809A1 - Método para la preparación de azoxistrobina - Google Patents
Método para la preparación de azoxistrobinaInfo
- Publication number
- AR113809A1 AR113809A1 ARP180103152A ARP180103152A AR113809A1 AR 113809 A1 AR113809 A1 AR 113809A1 AR P180103152 A ARP180103152 A AR P180103152A AR P180103152 A ARP180103152 A AR P180103152A AR 113809 A1 AR113809 A1 AR 113809A1
- Authority
- AR
- Argentina
- Prior art keywords
- azoxystrobin
- formula
- preparation
- represented
- trimethylamine catalyst
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- 238000002360 preparation method Methods 0.000 title abstract 4
- 239000005730 Azoxystrobin Substances 0.000 abstract 6
- WFDXOXNFNRHQEC-GHRIWEEISA-N azoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1OC1=CC(OC=2C(=CC=CC=2)C#N)=NC=N1 WFDXOXNFNRHQEC-GHRIWEEISA-N 0.000 abstract 6
- GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 abstract 6
- 239000003054 catalyst Substances 0.000 abstract 3
- CHZCERSEMVWNHL-UHFFFAOYSA-N 2-hydroxybenzonitrile Chemical compound OC1=CC=CC=C1C#N CHZCERSEMVWNHL-UHFFFAOYSA-N 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 238000006555 catalytic reaction Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000007613 environmental effect Effects 0.000 abstract 1
- 238000009776 industrial production Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 239000002351 wastewater Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
- B01J31/0234—Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
- B01J31/0235—Nitrogen containing compounds
- B01J31/0237—Amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/317—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/584—Recycling of catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
La presente proporciona un método para la preparación de azoxistrobina, que se lleva a cabo por medio de la reacción de 2-cianofenol o una sal del mismo con un compuesto representado por la fórmula (1) bajo la catálisis de un catalizador de trimetilamina para obtener la azoxistrobina representada por la fórmula (2), que permite que el rendimiento del producto de azoxistrobina llegue a 98% o más, que el rendimiento del producto separado llegue a 95% o más y que el procesamiento posterior sea sencillo. El catalizador de trimetilamina se puede reciclar y reutilizar en la síntesis del producto objetivo de azoxistrobina, que no sólo reduce el costo sino que también reduce el nitrógeno total y la COD en aguas residuales. Las ventajas con respecto al costo y la protección del medio ambiente del método de acuerdo con la presente son significativas y por lo tanto el método es adecuado para la producción industrial. Reivindicación 1: Un método de preparación para azoxistrobina, caracterizado porque el método de preparación comprende la reacción de 2-cianofenol o una sal del mismo con un compuesto representado por la fórmula (1) bajo la catálisis de un catalizador de trimetilamina para obtener la azoxistrobina representada por la fórmula (2).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711049391.6A CN109721548B (zh) | 2017-10-31 | 2017-10-31 | 一种嘧菌酯的制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR113809A1 true AR113809A1 (es) | 2020-06-10 |
Family
ID=61167935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP180103152A AR113809A1 (es) | 2017-10-31 | 2018-10-30 | Método para la preparación de azoxistrobina |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10189793B1 (es) |
| EP (1) | EP3476838B1 (es) |
| JP (1) | JP6714062B2 (es) |
| KR (1) | KR102132087B1 (es) |
| CN (1) | CN109721548B (es) |
| AR (1) | AR113809A1 (es) |
| AU (1) | AU2018250429B9 (es) |
| BR (1) | BR102018002942B1 (es) |
| CA (1) | CA3022444C (es) |
| DK (1) | DK3476838T3 (es) |
| EA (1) | EA036663B1 (es) |
| ES (1) | ES2767961T3 (es) |
| IL (1) | IL262340B (es) |
| LT (1) | LT3476838T (es) |
| NZ (1) | NZ747412A (es) |
| PL (1) | PL3476838T3 (es) |
| PT (1) | PT3476838T (es) |
| SI (1) | SI3476838T1 (es) |
| TW (1) | TWI688558B (es) |
| UA (1) | UA120414C2 (es) |
| ZA (1) | ZA201807239B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114685376B (zh) * | 2020-12-28 | 2024-06-07 | 北京颖泰嘉和生物科技股份有限公司 | 嘧菌酯中间体的制备方法 |
| CN114685377B (zh) * | 2020-12-31 | 2024-05-31 | 北京颖泰嘉和生物科技股份有限公司 | 嘧菌酯类化合物的制备方法 |
| CN114195723A (zh) * | 2021-11-30 | 2022-03-18 | 江苏七洲绿色科技研究院有限公司 | 一种嘧菌酯的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW234077B (es) * | 1992-07-17 | 1994-11-11 | Shell Internat Res Schappej B V | |
| SG63694A1 (en) | 1996-03-07 | 1999-03-30 | American Cyanamid Co | Process for the preparation of unsymmetrical 4,6-bis (aryloxy) pyrimidine compounds |
| US5849910A (en) * | 1997-09-05 | 1998-12-15 | American Cyanamid Company | Process for the preparation of unsymmetrical 4,6-bis aryloxy-pyrimidine compounds |
| GB0508422D0 (en) * | 2005-04-26 | 2005-06-01 | Syngenta Ltd | Chemical process |
| GB0619942D0 (en) | 2006-10-09 | 2006-11-15 | Syngenta Ltd | Chemical process |
| GB0619941D0 (en) * | 2006-10-09 | 2006-11-15 | Syngenta Ltd | Chemical process |
| CN102516122B (zh) * | 2011-11-08 | 2014-11-05 | 上海禾本药业有限公司 | 制备邻羟基苯甲腈的dmf溶液的方法 |
| KR101469879B1 (ko) * | 2012-12-27 | 2014-12-05 | 동부팜한농 주식회사 | 메틸 (e)-2-[2-[6-(2-시아노페녹시)피리미딘-4-일옥시]페닐]-3-메톡시아크릴레이트를 제조하는 방법 |
| CN103145627B (zh) | 2013-02-28 | 2015-10-07 | 河北威远生化农药有限公司 | 一种嘧菌酯的合成方法 |
| CN103265496B (zh) * | 2013-05-16 | 2015-02-25 | 北京颖泰嘉和生物科技有限公司 | 一种嘧菌酯的制备方法 |
| TWI621614B (zh) * | 2013-05-28 | 2018-04-21 | 科麥農股份有限公司 | 4,6-雙(芳氧基)嘧啶衍生物的製備方法 |
| CN104230820B (zh) | 2014-09-16 | 2016-09-28 | 重庆紫光国际化工有限责任公司 | 嘧菌酯的合成方法 |
-
2017
- 2017-10-31 CN CN201711049391.6A patent/CN109721548B/zh active Active
-
2018
- 2018-01-12 US US15/869,205 patent/US10189793B1/en active Active
- 2018-02-06 LT LTEP18155233.2T patent/LT3476838T/lt unknown
- 2018-02-06 ES ES18155233T patent/ES2767961T3/es active Active
- 2018-02-06 DK DK18155233.2T patent/DK3476838T3/da active
- 2018-02-06 PT PT181552332T patent/PT3476838T/pt unknown
- 2018-02-06 SI SI201830025T patent/SI3476838T1/sl unknown
- 2018-02-06 PL PL18155233T patent/PL3476838T3/pl unknown
- 2018-02-06 EP EP18155233.2A patent/EP3476838B1/en active Active
- 2018-02-15 BR BR102018002942-8A patent/BR102018002942B1/pt active IP Right Grant
- 2018-10-14 IL IL262340A patent/IL262340B/en active IP Right Grant
- 2018-10-18 NZ NZ74741218A patent/NZ747412A/en unknown
- 2018-10-18 AU AU2018250429A patent/AU2018250429B9/en active Active
- 2018-10-26 TW TW107137989A patent/TWI688558B/zh active
- 2018-10-29 CA CA3022444A patent/CA3022444C/en active Active
- 2018-10-30 ZA ZA2018/07239A patent/ZA201807239B/en unknown
- 2018-10-30 EA EA201892211A patent/EA036663B1/ru unknown
- 2018-10-30 KR KR1020180131012A patent/KR102132087B1/ko active IP Right Grant
- 2018-10-30 UA UAA201810721A patent/UA120414C2/uk unknown
- 2018-10-30 AR ARP180103152A patent/AR113809A1/es active IP Right Grant
- 2018-10-31 JP JP2018205286A patent/JP6714062B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PT3476838T (pt) | 2020-02-19 |
| BR102018002942B1 (pt) | 2020-11-10 |
| CA3022444C (en) | 2020-09-22 |
| ES2767961T3 (es) | 2020-06-19 |
| EA036663B1 (ru) | 2020-12-04 |
| KR102132087B1 (ko) | 2020-07-09 |
| AU2018250429A1 (en) | 2019-05-16 |
| AU2018250429B2 (en) | 2019-08-15 |
| AU2018250429B9 (en) | 2019-10-31 |
| CN109721548B (zh) | 2020-11-13 |
| NZ747412A (en) | 2019-11-29 |
| JP2019081758A (ja) | 2019-05-30 |
| PL3476838T3 (pl) | 2020-05-18 |
| TWI688558B (zh) | 2020-03-21 |
| KR20190049568A (ko) | 2019-05-09 |
| UA120414C2 (uk) | 2019-11-25 |
| EA201892211A3 (ru) | 2019-10-31 |
| TW201918475A (zh) | 2019-05-16 |
| JP6714062B2 (ja) | 2020-06-24 |
| IL262340A (en) | 2019-02-28 |
| DK3476838T3 (da) | 2020-02-10 |
| EP3476838A1 (en) | 2019-05-01 |
| IL262340B (en) | 2021-01-31 |
| CA3022444A1 (en) | 2019-04-30 |
| US10189793B1 (en) | 2019-01-29 |
| EA201892211A2 (ru) | 2019-06-28 |
| LT3476838T (lt) | 2020-01-27 |
| EP3476838B1 (en) | 2019-11-13 |
| ZA201807239B (en) | 2019-07-31 |
| SI3476838T1 (sl) | 2020-02-28 |
| BR102018002942A2 (pt) | 2019-06-04 |
| CN109721548A (zh) | 2019-05-07 |
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Legal Events
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| FG | Grant, registration |