AR112418A1 - Método para modular células de müller - Google Patents
Método para modular células de müllerInfo
- Publication number
- AR112418A1 AR112418A1 ARP180101494A AR112418A1 AR 112418 A1 AR112418 A1 AR 112418A1 AR P180101494 A ARP180101494 A AR P180101494A AR 112418 A1 AR112418 A1 AR 112418A1
- Authority
- AR
- Argentina
- Prior art keywords
- cells
- population
- umbilical cord
- human umbilical
- cord tissue
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Reproductive Health (AREA)
- Ophthalmology & Optometry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Prostheses (AREA)
Abstract
Se describen métodos y composiciones para tratar enfermedades oftálmicas, particularmente, la degeneración retinal, que incluyen la modulación de la glía de Müller, la restauración de la conectividad sináptica retinal y la formación de sinapsis que contienen a2d1, mediante el uso de células derivadas del posparto. Reivindicación 1: Una población de células derivadas del posparto para usar en la modulación de la glía de Müller en la degeneración retinal, en donde la población de células es una población homogénea de células derivadas de tejido del cordón umbilical humano, y en donde las células derivadas de tejido del cordón umbilical humano se aíslan de tejido del cordón umbilical humano sustancialmente libres de sangre, en donde la población de células se autorenueva y se expande en cultivo y no expresa CD117, y en donde la población de células secreta trombospondina-1 (TSP1) o trombospondina-1 (TSP2).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762514329P | 2017-06-02 | 2017-06-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR112418A1 true AR112418A1 (es) | 2019-10-30 |
Family
ID=64454469
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP180101494 AR112418A1 (es) | 2017-06-02 | 2018-06-04 | Método para modular células de müller |
Country Status (4)
Country | Link |
---|---|
US (1) | US20180344777A1 (es) |
AR (1) | AR112418A1 (es) |
TW (1) | TW201908478A (es) |
WO (1) | WO2018220490A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1933852B1 (en) | 2005-09-27 | 2018-12-19 | TissueTech, Inc. | Amniotic membrane preparations and purified compositions and methods of use |
KR102236805B1 (ko) | 2012-07-11 | 2021-04-05 | 티슈테크, 인코포레이티드 | Hc-ha/ptx3 복합체를 함유하는 조성물 및 이의 사용 방법 |
US20160243288A1 (en) | 2015-02-23 | 2016-08-25 | Tissuetech, Inc. | Apparatuses and methods for treating ophthalmic diseases and disorders |
EP3297645A4 (en) | 2015-05-20 | 2018-12-12 | Tissuetech, Inc. | Compositions and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells |
TW201733600A (zh) | 2016-01-29 | 2017-10-01 | 帝聖工業公司 | 胎兒扶持組織物及使用方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE473751T1 (de) * | 2000-02-11 | 2010-07-15 | Schepens Eye Res Inst | Isolierung und transplantation von retinalen stammzellen |
US8790637B2 (en) * | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
KR101515369B1 (ko) * | 2013-01-11 | 2015-04-30 | (주)차바이오텍 | 인간 제대혈 유래 내피 전구세포의 배양방법 및 인간 제대혈 유래 내피 전구세포를 포함하는 허혈성 질환의 예방 또는 치료용 조성물 |
US20170080033A1 (en) * | 2014-12-16 | 2017-03-23 | Janssen Biotech, Inc. | Treatment of retinal degeneration using progenitor cells |
-
2018
- 2018-05-24 US US15/988,821 patent/US20180344777A1/en not_active Abandoned
- 2018-05-24 WO PCT/IB2018/053719 patent/WO2018220490A1/en active Application Filing
- 2018-05-31 TW TW107118633A patent/TW201908478A/zh unknown
- 2018-06-04 AR ARP180101494 patent/AR112418A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
US20180344777A1 (en) | 2018-12-06 |
WO2018220490A1 (en) | 2018-12-06 |
TW201908478A (zh) | 2019-03-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR112418A1 (es) | Método para modular células de müller | |
CO2020005645A2 (es) | Proteínas trispecificas y métodos de uso | |
CO2019014682A2 (es) | Composiciones y métodos para enzimas de internalización | |
MX2017004890A (es) | Metodos y composiciones para la generación o el mantenimiento de células pluripotentes. | |
MX2020011029A (es) | Formulaciones y metodos de tratamiento con queratina. | |
EP4349854A3 (en) | Pd1-cd28 fusion proteins and their use in medicine | |
WO2017035314A8 (en) | Treatments for mitral valve insufficiency | |
AU2017241807A1 (en) | Medium, methods, cells and secreted factors for stem cell culture and therapy | |
MX2017000107A (es) | Sistema para anuloplastia. | |
EP4269566A3 (en) | Genetic markers for engraftment of human cardiac ventricular progenitor cells | |
EA201792635A1 (ru) | Устройство и способ культивирования тканей | |
WO2018220489A3 (en) | METHODS OF OBTAINING CELLS FROM HUMAN OMBILICAL POST-PARTUM CORDON ARTERIAL TISSUE | |
CO2019000096A2 (es) | Variantes de la protoporfirinógeno oxidasa y métodos y composiciones para conferir y/o mejorar la tolerancia a herbicidas utilizando las mismas | |
AR113562A1 (es) | Método para inhibir la angiogénesis | |
CL2017002357A1 (es) | Método de obtención de una composición que contiene una población específica de células mesenquimales de cordón umbilical y sus usos | |
CL2019003459A1 (es) | Métodos de cultivo celular. | |
CL2018002122A1 (es) | Concentrados de proteína a partir de aceite de semillas y métodos para producirlos | |
AR108972A1 (es) | Tratamiento de la enfermedad vascular retiniana mediante el uso de células progenitoras | |
RU2018122461A (ru) | Лечение дегенерации сетчатки с применением клеток-предшественников | |
AR112771A1 (es) | Método para evaluar la hidratación bioactiva de un ingrediente o de una mezcla de ingredientes, composiciones cosméticas para la modulación de genes responsables de la hidratación bioactiva de la piel y método para la modulación de la expresión de genes responsables de la hidratación bioactiva de la piel | |
CL2022000315A1 (es) | Composición cosmética tópica, uso de la composición y tónico para aplicación facial | |
MX2020001274A (es) | Fotoregulina3, moduladora de los genes de los fotorreceptores para el tratamiento de enfermedades de la retina. | |
BR112021020358A2 (pt) | Complexo cosmético e usos do mesmo | |
UA115089C2 (uk) | Медичний продукт на основі клітин людини для корекції остеорепаративних процесів | |
WO2022169884A3 (en) | Artificial expression constructs for modulating gene expression in gabaergic neurons and astrocytes |