AR101847A1 - Generación de sitios de integración sitio específica para loci de rasgos complejos en maíz y poroto de soja, y métodos de uso - Google Patents
Generación de sitios de integración sitio específica para loci de rasgos complejos en maíz y poroto de soja, y métodos de usoInfo
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- AR101847A1 AR101847A1 ARP150102908A ARP150102908A AR101847A1 AR 101847 A1 AR101847 A1 AR 101847A1 AR P150102908 A ARP150102908 A AR P150102908A AR P150102908 A ARP150102908 A AR P150102908A AR 101847 A1 AR101847 A1 AR 101847A1
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/46—Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
- A01H6/4684—Zea mays [maize]
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
- C12N15/8289—Male sterility
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
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- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
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- Wood Science & Technology (AREA)
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- Plant Pathology (AREA)
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- Cell Biology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
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- Botany (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
- Medicinal Chemistry (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
Abstract
Reivindicación 1: Una planta de maíz, parte de planta de maíz o semilla de maíz caracterizada porque tiene en su genoma una ventana genómica que comprende al menos un sitio objetivo transgénico para integración especifica de sitio (SSI) integrado en al menos un sitio objetivo de ruptura de cadena doble, en donde dicha ventana genómica está flanqueada por: a) al menos un primer marcador que comprende SYN12545, SYN12536, SYN14645, PZE-101023852, PZE-101024424, SYN25022, SYN31156, SYN31166 o SYN22238; y, b) al menos un segundo marcador que comprende SYN12536, SYN14645, PZE-101023852, PZE-101024424, SYN25022, SYN31156, SYN31166, SYN22238 o SYN20196. Reivindicación 6: La planta de maíz, parte de la planta de maíz o semilla de maíz de la reivindicación 1, caracterizada porque dicha ventana genómica comprende, además, al menos un primer, segundo, tercero, cuarto, quinto, sexto, séptimo, octavo, noveno, décimo, décimo primero, décimo segundo, decimotercero, decimocuarto, decimoquinto, decimosexto, decimosétimo, décimooctavo, décimonoveno, vigésimo, vigésimoprimero, vigésimosegundo, vigésimotercero, vigésimocuarto, vigésimo quinto, vigésimosexto, vigésimoséptimo, vigésimooctavo, vigésimonoveno, trigésimo, o trigésimoprimero sitio objetivo transgénico para la integración sitio especifica integrado en al menos un segundo, tercero, cuarto, quinto, sexto, séptimo, octavo, noveno, décimo, décimoprimero, décimosegundo, decimotercero, decimocuarto, decimoquinto, decimosexto, decimosétimo, décimooctavo, decimonoveno, vigésimo, vigésimoprimero, vigésimosegundo, vigésimotercero, vigésimocuarto, vigésimoquinto, vigésimosexto, vigésimoséptimo, vigésimooctavo, vigésimonoveno, trigésimo, o trigésimoprimero sitio objetivo de interrupción de la cadena doble. Reivindicación 22: Una planta de maíz, parte de planta de maíz o semilla de maíz caracterizada porque tiene en su genoma una ventana genómica que comprende al menos un sitio objetivo de ruptura de cadena doble modificado, en donde dicha ventana genómica está flanqueada por: a) al menos un primer marcador que comprende SYN12545, SYN12536, SYN14645, PZE-101023852, PZE-101024424, SYN25022, SYN31156, SYN31166 o SYN22238; y, b) al menos un segundo marcador que comprende SYN12536, SYN14645, PZE-101023852, PZE-101024424, . SYN25022, SYN31156, SYN31166, SYN22238 o SYN20196.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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US201462049465P | 2014-09-12 | 2014-09-12 |
Publications (1)
Publication Number | Publication Date |
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AR101847A1 true AR101847A1 (es) | 2017-01-18 |
Family
ID=54140668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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ARP150102908A AR101847A1 (es) | 2014-09-12 | 2015-09-11 | Generación de sitios de integración sitio específica para loci de rasgos complejos en maíz y poroto de soja, y métodos de uso |
Country Status (11)
Country | Link |
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US (2) | US11560568B2 (es) |
EP (2) | EP3628739B1 (es) |
CN (1) | CN108064129A (es) |
AR (1) | AR101847A1 (es) |
AU (1) | AU2015315651A1 (es) |
BR (1) | BR112017003757A2 (es) |
CA (1) | CA2956487A1 (es) |
IL (1) | IL250256A0 (es) |
MX (1) | MX2017002930A (es) |
RU (1) | RU2017112324A (es) |
WO (1) | WO2016040030A1 (es) |
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US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
US9340800B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | Extended DNA-sensing GRNAS |
US20150166982A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting pi3k point mutations |
US10077453B2 (en) | 2014-07-30 | 2018-09-18 | President And Fellows Of Harvard College | CAS9 proteins including ligand-dependent inteins |
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AR106430A1 (es) | 2015-10-16 | 2018-01-17 | Pioneer Hi Bred Int | Generación de plantas de maíz con resistencia mejorada al tizón norteño de las hojas |
EP4269577A3 (en) | 2015-10-23 | 2024-01-17 | President and Fellows of Harvard College | Nucleobase editors and uses thereof |
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CN106811479B (zh) * | 2015-11-30 | 2019-10-25 | 中国农业科学院作物科学研究所 | 利用CRISPR/Cas9***定点修饰ALS基因获得抗除草剂水稻的***及其应用 |
SG11201900907YA (en) | 2016-08-03 | 2019-02-27 | Harvard College | Adenosine nucleobase editors and uses thereof |
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US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
CN109844121A (zh) * | 2016-10-13 | 2019-06-04 | 先锋国际良种公司 | 产生北方叶枯病抗性玉蜀黍 |
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US10745677B2 (en) | 2016-12-23 | 2020-08-18 | President And Fellows Of Harvard College | Editing of CCR5 receptor gene to protect against HIV infection |
EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
EP3592777A1 (en) | 2017-03-10 | 2020-01-15 | President and Fellows of Harvard College | Cytosine to guanine base editor |
CN110914426A (zh) | 2017-03-23 | 2020-03-24 | 哈佛大学的校长及成员们 | 包含核酸可编程dna结合蛋白的核碱基编辑器 |
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-
2015
- 2015-08-31 RU RU2017112324A patent/RU2017112324A/ru not_active Application Discontinuation
- 2015-08-31 BR BR112017003757A patent/BR112017003757A2/pt not_active Application Discontinuation
- 2015-08-31 CN CN201580048807.5A patent/CN108064129A/zh active Pending
- 2015-08-31 EP EP19206649.6A patent/EP3628739B1/en active Active
- 2015-08-31 MX MX2017002930A patent/MX2017002930A/es unknown
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- 2015-08-31 EP EP15763713.3A patent/EP3191595B1/en active Active
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- 2015-08-31 AU AU2015315651A patent/AU2015315651A1/en not_active Abandoned
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US20230212595A1 (en) | 2023-07-06 |
RU2017112324A3 (es) | 2019-03-04 |
CN108064129A (zh) | 2018-05-22 |
CA2956487A1 (en) | 2016-03-17 |
EP3628739A1 (en) | 2020-04-01 |
US20180230476A1 (en) | 2018-08-16 |
WO2016040030A1 (en) | 2016-03-17 |
EP3191595A1 (en) | 2017-07-19 |
RU2017112324A (ru) | 2018-10-15 |
US11560568B2 (en) | 2023-01-24 |
EP3191595B1 (en) | 2019-12-25 |
EP3628739B1 (en) | 2024-05-01 |
BR112017003757A2 (pt) | 2017-12-26 |
MX2017002930A (es) | 2017-06-06 |
IL250256A0 (en) | 2017-03-30 |
AU2015315651A1 (en) | 2017-02-16 |
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