AR093335A1 - Sales amina de laquinimod - Google Patents
Sales amina de laquinimodInfo
- Publication number
- AR093335A1 AR093335A1 ARP130104013A ARP130104013A AR093335A1 AR 093335 A1 AR093335 A1 AR 093335A1 AR P130104013 A ARP130104013 A AR P130104013A AR P130104013 A ARP130104013 A AR P130104013A AR 093335 A1 AR093335 A1 AR 093335A1
- Authority
- AR
- Argentina
- Prior art keywords
- laquinimod
- amina
- salts
- iisin
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/40—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton with quaternised nitrogen atoms bound to carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
Abstract
Sal amina de laquinimod, que es meglumina de laquinimod, hidróxido de colina de laquinimod, L-Iisina de laquinimod o monoetanolamina de laquinimod. Útil para ser utilizada en terapia de la esclerosis múltiple.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261723495P | 2012-11-07 | 2012-11-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR093335A1 true AR093335A1 (es) | 2015-06-03 |
Family
ID=50622908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP130104013A AR093335A1 (es) | 2012-11-07 | 2013-11-01 | Sales amina de laquinimod |
Country Status (15)
Country | Link |
---|---|
US (1) | US8975279B2 (es) |
EP (1) | EP2916915A4 (es) |
JP (1) | JP2015535287A (es) |
KR (1) | KR20150091077A (es) |
CN (1) | CN104955522A (es) |
AR (1) | AR093335A1 (es) |
AU (1) | AU2013341506A1 (es) |
BR (1) | BR112015010193A2 (es) |
CA (1) | CA2890194A1 (es) |
EA (1) | EA201590788A1 (es) |
HK (2) | HK1212936A1 (es) |
IL (1) | IL238535A0 (es) |
MX (1) | MX2015005632A (es) |
TW (1) | TW201422588A (es) |
WO (1) | WO2014074381A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112014018485A8 (pt) | 2012-02-03 | 2017-07-11 | Teva Pharma | Uso de laquinimod para tratar pacientes com a doença de crohn que falharam com a primeira linha de terapia anti-tnf |
MX2014009889A (es) | 2012-02-16 | 2014-11-13 | Teva Pharma | N-etil-n-fenil-1,2-dihidro-4,5-di-hidroxi-1-metil-2-oxo-3-quinoli ncarboxamida, preparacion y usos de los mismos. |
TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
HUE053654T2 (hu) | 2014-03-26 | 2021-07-28 | Astex Therapeutics Ltd | FGFR- és CMET-inhibitorok kombinációi a rák kezelésére |
CN106573014A (zh) | 2014-04-29 | 2017-04-19 | 梯瓦制药工业有限公司 | 用于治疗具有高残疾状况的复发‑缓解型多发性硬化症(rrms)的患者的拉喹莫德 |
JOP20200201A1 (ar) | 2015-02-10 | 2017-06-16 | Astex Therapeutics Ltd | تركيبات صيدلانية تشتمل على n-(3.5- ثنائي ميثوكسي فينيل)-n'-(1-ميثيل إيثيل)-n-[3-(ميثيل-1h-بيرازول-4-يل) كينوكسالين-6-يل]إيثان-1.2-ثنائي الأمين |
US20180071376A1 (en) | 2015-03-23 | 2018-03-15 | The Brigham And Women`S Hospital, Inc. | Tolerogenic nanoparticles for treating diabetes mellitus |
US20210220481A1 (en) | 2018-08-03 | 2021-07-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Biocompatible tolerogenic nanoparticles |
EP3886893A1 (en) | 2018-11-27 | 2021-10-06 | Institut National De La Sante Et De La Recherche Medicale - Inserm | Nanoparticles for preparing regulatory b cells |
KR20210124855A (ko) | 2020-04-07 | 2021-10-15 | 주식회사 엘에스파마 | 고미가 차폐된 디클로페낙을 함유하는 약제학적 조성물 |
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BR112014018485A8 (pt) | 2012-02-03 | 2017-07-11 | Teva Pharma | Uso de laquinimod para tratar pacientes com a doença de crohn que falharam com a primeira linha de terapia anti-tnf |
MX2014009889A (es) | 2012-02-16 | 2014-11-13 | Teva Pharma | N-etil-n-fenil-1,2-dihidro-4,5-di-hidroxi-1-metil-2-oxo-3-quinoli ncarboxamida, preparacion y usos de los mismos. |
US20130259856A1 (en) | 2012-03-27 | 2013-10-03 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and dimethyl fumarate |
TW201347762A (zh) | 2012-05-02 | 2013-12-01 | Teva Pharma | 高劑量拉喹莫德(laquinimod)於治療多發性硬化症之用途 |
TW201350467A (zh) * | 2012-05-08 | 2013-12-16 | Teva Pharma | N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺 |
WO2014004733A1 (en) | 2012-06-26 | 2014-01-03 | The Regents Of The University Of California | Composition for lupus nephritis and methods of making and using the same |
AR091706A1 (es) | 2012-07-11 | 2015-02-25 | Teva Pharma | Formulaciones de laquinimod sin agentes alcalinizantes |
UY34896A (es) | 2012-07-12 | 2014-02-28 | Teva Pharma | Tratamiento de la esclerosis múltiple con una combinación de laquinimod y fampridina |
TW201410243A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療***素受體型1(cb1)媒介之疾病之拉喹莫德(laquinimod) |
TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
-
2013
- 2013-10-31 AU AU2013341506A patent/AU2013341506A1/en not_active Abandoned
- 2013-10-31 US US14/068,599 patent/US8975279B2/en not_active Expired - Fee Related
- 2013-10-31 WO PCT/US2013/067686 patent/WO2014074381A1/en active Application Filing
- 2013-10-31 CN CN201380058339.0A patent/CN104955522A/zh active Pending
- 2013-10-31 CA CA2890194A patent/CA2890194A1/en not_active Abandoned
- 2013-10-31 KR KR1020157014911A patent/KR20150091077A/ko not_active Application Discontinuation
- 2013-10-31 MX MX2015005632A patent/MX2015005632A/es unknown
- 2013-10-31 JP JP2015540779A patent/JP2015535287A/ja active Pending
- 2013-10-31 EP EP13852663.7A patent/EP2916915A4/en not_active Withdrawn
- 2013-10-31 EA EA201590788A patent/EA201590788A1/ru unknown
- 2013-10-31 BR BR112015010193A patent/BR112015010193A2/pt active Search and Examination
- 2013-11-01 AR ARP130104013A patent/AR093335A1/es unknown
- 2013-11-05 TW TW102140149A patent/TW201422588A/zh unknown
-
2015
- 2015-04-30 IL IL238535A patent/IL238535A0/en unknown
-
2016
- 2016-01-25 HK HK16100794.0A patent/HK1212936A1/zh unknown
- 2016-03-21 HK HK16103249.5A patent/HK1215210A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20140128430A1 (en) | 2014-05-08 |
AU2013341506A1 (en) | 2015-06-04 |
JP2015535287A (ja) | 2015-12-10 |
BR112015010193A2 (pt) | 2017-07-11 |
MX2015005632A (es) | 2016-02-05 |
EA201590788A1 (ru) | 2015-12-30 |
US8975279B2 (en) | 2015-03-10 |
EP2916915A4 (en) | 2016-06-22 |
CN104955522A (zh) | 2015-09-30 |
HK1215210A1 (zh) | 2016-08-19 |
WO2014074381A1 (en) | 2014-05-15 |
HK1212936A1 (zh) | 2016-06-24 |
KR20150091077A (ko) | 2015-08-07 |
IL238535A0 (en) | 2015-06-30 |
TW201422588A (zh) | 2014-06-16 |
EP2916915A1 (en) | 2015-09-16 |
CA2890194A1 (en) | 2014-05-15 |
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