AR072032A1 - Tratamiento de enfermedades inflamatorias del intestino con beta defensinas de mamiferos - Google Patents

Tratamiento de enfermedades inflamatorias del intestino con beta defensinas de mamiferos

Info

Publication number
AR072032A1
AR072032A1 ARP090102741A ARP090102741A AR072032A1 AR 072032 A1 AR072032 A1 AR 072032A1 AR P090102741 A ARP090102741 A AR P090102741A AR P090102741 A ARP090102741 A AR P090102741A AR 072032 A1 AR072032 A1 AR 072032A1
Authority
AR
Argentina
Prior art keywords
treatment
defenses
intestine
mammals
beta
Prior art date
Application number
ARP090102741A
Other languages
English (en)
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41530820&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR072032(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novozymes As filed Critical Novozymes As
Publication of AR072032A1 publication Critical patent/AR072032A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1729—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reivindicacion 1: El uso de una beta defensina de mam¡fero en la elaboracion de un medicamento para la administracion parenteral en el tratamiento de una enfermedad inflamatoria intestinal. Reivindicacion 5: El uso de acuerdo con cualquiera de las reivindicaciones 1-4, en el cual la beta defensina de mam¡fero tiene por lo menos 80% de identidad con las secuencias de amino cidos de SEQ ID Nø:1, SEQ ID Nø:2, SEQ ID Nø: 3 o SEQ ID Nø:4.
ARP090102741A 2008-07-18 2009-07-17 Tratamiento de enfermedades inflamatorias del intestino con beta defensinas de mamiferos AR072032A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08160761 2008-07-18
EP08162486 2008-08-15
EP08163614 2008-09-03

Publications (1)

Publication Number Publication Date
AR072032A1 true AR072032A1 (es) 2010-07-28

Family

ID=41530820

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP090102741A AR072032A1 (es) 2008-07-18 2009-07-17 Tratamiento de enfermedades inflamatorias del intestino con beta defensinas de mamiferos
ARP110102093A AR081948A2 (es) 2008-07-18 2011-06-16 USO DE b DEFENSINAS DE MAMIFEROS PARA LA MANUFACTURA DE MEDICAMENTOS PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS DEL INTESTINO

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP110102093A AR081948A2 (es) 2008-07-18 2011-06-16 USO DE b DEFENSINAS DE MAMIFEROS PARA LA MANUFACTURA DE MEDICAMENTOS PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS DEL INTESTINO

Country Status (20)

Country Link
US (4) US8232242B2 (es)
EP (2) EP2399600A1 (es)
JP (2) JP2011528333A (es)
KR (1) KR20110092325A (es)
CN (2) CN102247591A (es)
AP (2) AP2011005538A0 (es)
AR (2) AR072032A1 (es)
AU (1) AU2009272681A1 (es)
BR (2) BRPI0924481A2 (es)
CA (2) CA2750727A1 (es)
CL (1) CL2011000099A1 (es)
EA (2) EA201100910A1 (es)
IL (2) IL210715A0 (es)
MX (1) MX2011000568A (es)
NZ (2) NZ590468A (es)
PH (1) PH12012501542A1 (es)
SG (1) SG172709A1 (es)
TW (2) TW201004640A (es)
WO (1) WO2010007166A2 (es)
ZA (1) ZA201100461B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2399600A1 (en) 2008-07-18 2011-12-28 Novozymes Adenium Biotech A/S Treatment of inflammatory bowel diseases with mammal beta defensins
CA2730666A1 (en) * 2008-07-18 2010-01-21 Novozymes Adenium Biotech A/S Treatment of rheumatoid arthritis with mammal beta defensins
AR072524A1 (es) * 2008-07-18 2010-09-01 Novozymes As Tratamiento de enfermedades inflamatorias con beta defensinas de mamiferos
KR101329774B1 (ko) * 2010-06-16 2013-11-15 주식회사 나이벡 항균 또는 항염증 활성을 가지는 펩타이드 및 이를 유효성분으로 함유하는 약제학적 조성물
NZ732118A (en) 2011-04-15 2018-11-30 Marine Polymer Tech Inc Treatment of disease with poly-n-acetylglucosamine nanofibers
WO2013007596A2 (en) 2011-07-08 2013-01-17 Novozymes A/S Oral treatment of inflammatory bowel disease
WO2013026794A1 (en) 2011-08-19 2013-02-28 Novozymes Novel immunomodulatory peptide
US10257564B2 (en) * 2013-01-24 2019-04-09 Saturn Licensing Llc Distributed non-real-time content
CN104628864B (zh) * 2013-11-14 2020-04-10 中国医学科学院医药生物技术研究所 一种抗肿瘤融合蛋白EL-defensin、其编码基因和用途
JP2019514908A (ja) 2016-04-29 2019-06-06 ディフェンシン セラピューティクス エーピーエス 肝臓、胆管および膵臓の障害の治療
CA3045079A1 (en) 2016-12-13 2018-06-21 Defensin Therapeutics Aps Methods for treating inflammatory conditions of the lungs
CN111556759A (zh) 2017-11-10 2020-08-18 防御素治疗学公司 早产儿中的粘膜防御和肠道/肺功能的成熟化
MX2020005370A (es) 2017-11-24 2020-10-19 Defensin Therapeutics Aps Prevencion y tratamiento de enfermedad de injerto contra hospedero con defensinas.
KR102244161B1 (ko) * 2018-08-31 2021-04-26 주식회사 나이벡 다중의 질환 바이오마커의 기능 및 발현을 억제하는 펩타이드의 신규한 용도
CN113684162B (zh) * 2021-06-03 2024-02-27 江南大学 一种表达小鼠防御素mBD14基因的重组植物乳杆菌及其应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6576755B1 (en) * 1997-09-10 2003-06-10 Zymogenetics, Inc. Beta-defensins
DE19957043A1 (de) * 1999-11-26 2001-06-07 Forssmann Wolf Georg Neue Defensine
US7338936B2 (en) * 2000-11-28 2008-03-04 House Ear Institute Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis
US20080194481A1 (en) * 2001-12-21 2008-08-14 Human Genome Sciences, Inc. Albumin Fusion Proteins
FR2841556B1 (fr) 2002-07-01 2007-07-20 Centre Nat Rech Scient Peptides ayant des proprietes antimicrobiennes et les compositions les contenant notamment pour la conservation des aliments
CA2508273A1 (en) 2002-12-19 2004-07-08 Yitzchak Hillman Disease treatment via antimicrobial peptide inhibitors
US20070207209A1 (en) 2004-08-27 2007-09-06 Murphy Christopher J Trophic factor combinations for nervous system treatment
GB0514482D0 (en) * 2005-07-14 2005-08-17 Ares Trading Sa Protein
WO2007081486A2 (en) * 2005-12-15 2007-07-19 Ventria Bioscience Oral administration of defensins to treat intestinal diseases
WO2007087557A2 (en) 2006-01-24 2007-08-02 University Of Maryland Biotechnology Institute Surface-layer protein coated microspheres and uses thereof
CA2699163A1 (en) * 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
AR072524A1 (es) 2008-07-18 2010-09-01 Novozymes As Tratamiento de enfermedades inflamatorias con beta defensinas de mamiferos
CA2730666A1 (en) 2008-07-18 2010-01-21 Novozymes Adenium Biotech A/S Treatment of rheumatoid arthritis with mammal beta defensins
EP2399600A1 (en) 2008-07-18 2011-12-28 Novozymes Adenium Biotech A/S Treatment of inflammatory bowel diseases with mammal beta defensins
WO2013007596A2 (en) 2011-07-08 2013-01-17 Novozymes A/S Oral treatment of inflammatory bowel disease
WO2013026794A1 (en) 2011-08-19 2013-02-28 Novozymes Novel immunomodulatory peptide

Also Published As

Publication number Publication date
BRPI0915973A2 (pt) 2013-05-07
AR081948A2 (es) 2012-10-31
JP2011528333A (ja) 2011-11-17
US20110251139A1 (en) 2011-10-13
ZA201100461B (en) 2014-03-26
KR20110092325A (ko) 2011-08-17
IL210715A0 (en) 2011-03-31
EP2399600A1 (en) 2011-12-28
EA201100910A1 (ru) 2012-05-30
US8232242B2 (en) 2012-07-31
JP2011225596A (ja) 2011-11-10
TW201004640A (en) 2010-02-01
CA2750727A1 (en) 2010-01-21
CL2011000099A1 (es) 2011-10-07
CA2730789A1 (en) 2010-01-21
IL213680A0 (en) 2011-07-31
SG172709A1 (en) 2011-07-28
CN102247591A (zh) 2011-11-23
US20120309678A1 (en) 2012-12-06
US20100016230A1 (en) 2010-01-21
CN102159233A (zh) 2011-08-17
US8802621B2 (en) 2014-08-12
PH12012501542A1 (en) 2015-11-09
NZ593653A (en) 2012-09-28
BRPI0924481A2 (pt) 2015-08-11
WO2010007166A3 (en) 2010-06-03
EP2320930A2 (en) 2011-05-18
AP2011005538A0 (en) 2011-02-28
EA201170219A1 (ru) 2011-08-30
MX2011000568A (es) 2011-02-23
AU2009272681A1 (en) 2010-01-21
TW201138810A (en) 2011-11-16
NZ590468A (en) 2012-06-29
WO2010007166A2 (en) 2010-01-21
US9279010B2 (en) 2016-03-08
AP2011005755A0 (en) 2011-06-30
US20140135258A1 (en) 2014-05-15

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