AR069958A1 - Metodo para producir una proteina heterologa de interes - Google Patents
Metodo para producir una proteina heterologa de interesInfo
- Publication number
- AR069958A1 AR069958A1 ARP080105694A ARP080105694A AR069958A1 AR 069958 A1 AR069958 A1 AR 069958A1 AR P080105694 A ARP080105694 A AR P080105694A AR P080105694 A ARP080105694 A AR P080105694A AR 069958 A1 AR069958 A1 AR 069958A1
- Authority
- AR
- Argentina
- Prior art keywords
- interest
- protein
- producing
- heterology
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
También se proveen un vector de expresion, una célula, composiciones farmacéuticas, método para tratar el cáncer, enfermedades autoinmunes e inflamacion y uso diagnostico. Reivindicacion 1: Un método para producir una proteína heterologa de interés en una célula, caracterizado porque comprende: a) aumentar la expresion de al menos un gen que codifica una proteína del grupo de proteínas SEC1/Munc 18 (proteínas SM) y b) llevar a efecto la expresion de dicha proteína heterologa de interés.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07150254 | 2007-12-20 | ||
EP08152829 | 2008-03-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR069958A1 true AR069958A1 (es) | 2010-03-03 |
Family
ID=40344722
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080105694A Pending AR069958A1 (es) | 2007-12-20 | 2008-12-23 | Metodo para producir una proteina heterologa de interes |
Country Status (14)
Country | Link |
---|---|
US (1) | US20090247609A1 (es) |
EP (1) | EP2225389A1 (es) |
JP (1) | JP2011505850A (es) |
KR (1) | KR20100099190A (es) |
CN (1) | CN101903529A (es) |
AR (1) | AR069958A1 (es) |
AU (1) | AU2008340652A1 (es) |
BR (1) | BRPI0821389A2 (es) |
CA (1) | CA2709645A1 (es) |
EA (1) | EA201000945A1 (es) |
IL (1) | IL205239A0 (es) |
NZ (1) | NZ586037A (es) |
TW (1) | TW200932907A (es) |
WO (1) | WO2009080299A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2774470A1 (en) | 2009-09-18 | 2011-03-24 | Selexis S.A. | Products and methods for enhanced transgene expression and processing |
TW201823460A (zh) * | 2012-05-29 | 2018-07-01 | 美商再生元醫藥公司 | 生產細胞株增強子 |
ES2717175T3 (es) | 2013-02-01 | 2019-06-19 | Selexis Sa | Expresión mejorada de transgenes y procesamiento |
JP6772138B2 (ja) * | 2014-12-19 | 2020-10-21 | メルツ ファルマ ゲーエムベーハー ウント コンパニー カーゲーアーアー | 細胞内のBoNT/Eの生物学的活性を決定するための手段及び方法 |
CN106554973B (zh) * | 2015-09-30 | 2020-05-22 | 北京吉尚立德生物科技有限公司 | 一种cho细胞分泌能力评价*** |
WO2023155881A1 (en) * | 2022-02-18 | 2023-08-24 | Tsinghua University | Methods for regulating secretion via migrasomes |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI924494A0 (fi) * | 1992-10-06 | 1992-10-06 | Valtion Teknillinen | Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller |
WO1999007862A1 (en) * | 1997-08-05 | 1999-02-18 | Chiron Corporation | Novel pichia pastoris gene sequences and methods for their use |
AU2002952550A0 (en) * | 2002-11-08 | 2002-11-21 | The University Of Queensland | Modulating TNFalpha Secretion |
-
2008
- 2008-12-17 US US12/336,612 patent/US20090247609A1/en not_active Abandoned
- 2008-12-19 KR KR1020107013514A patent/KR20100099190A/ko not_active Application Discontinuation
- 2008-12-19 EP EP08864314A patent/EP2225389A1/en not_active Withdrawn
- 2008-12-19 AU AU2008340652A patent/AU2008340652A1/en not_active Abandoned
- 2008-12-19 CA CA2709645A patent/CA2709645A1/en not_active Abandoned
- 2008-12-19 WO PCT/EP2008/010882 patent/WO2009080299A1/en active Application Filing
- 2008-12-19 EA EA201000945A patent/EA201000945A1/ru unknown
- 2008-12-19 CN CN2008801221856A patent/CN101903529A/zh active Pending
- 2008-12-19 NZ NZ586037A patent/NZ586037A/xx not_active IP Right Cessation
- 2008-12-19 BR BRPI0821389-5A patent/BRPI0821389A2/pt not_active IP Right Cessation
- 2008-12-19 JP JP2010538474A patent/JP2011505850A/ja active Pending
- 2008-12-19 TW TW097149850A patent/TW200932907A/zh unknown
- 2008-12-23 AR ARP080105694A patent/AR069958A1/es active Pending
-
2010
- 2010-04-22 IL IL205239A patent/IL205239A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EA201000945A1 (ru) | 2011-02-28 |
BRPI0821389A2 (pt) | 2015-06-16 |
IL205239A0 (en) | 2010-11-30 |
KR20100099190A (ko) | 2010-09-10 |
US20090247609A1 (en) | 2009-10-01 |
TW200932907A (en) | 2009-08-01 |
WO2009080299A1 (en) | 2009-07-02 |
CN101903529A (zh) | 2010-12-01 |
NZ586037A (en) | 2012-08-31 |
JP2011505850A (ja) | 2011-03-03 |
AU2008340652A1 (en) | 2009-07-02 |
WO2009080299A8 (en) | 2010-04-15 |
EP2225389A1 (en) | 2010-09-08 |
CA2709645A1 (en) | 2009-07-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |