AR069860A1 - Metodo para purificar un anticuerpo cd20 - Google Patents
Metodo para purificar un anticuerpo cd20Info
- Publication number
- AR069860A1 AR069860A1 ARP080105605A ARP080105605A AR069860A1 AR 069860 A1 AR069860 A1 AR 069860A1 AR P080105605 A ARP080105605 A AR P080105605A AR P080105605 A ARP080105605 A AR P080105605A AR 069860 A1 AR069860 A1 AR 069860A1
- Authority
- AR
- Argentina
- Prior art keywords
- antibody
- purifying
- mixture
- hccf
- recovering
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La mezcla consistiendo en un fluido celular cosechado concentrado (HCCF) de un cultivo celular recombinante que produce el anticuerpo CD20, no ha sido sometida a liofilizacion previa. También se proveen cristales de un anticuerpo CD20, una composicion farmacéutica y un método de tratamiento de una enfermedad o afeccion asociada a CD20. Reivindicacion 1: Un método para purificar un anticuerpo CD20 de una mezcla, caracterizado porque comprende cristalizar el anticuerpo CD20 y recuperar el anticuerpo CD20 de la mezcla.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1628807P | 2007-12-21 | 2007-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR069860A1 true AR069860A1 (es) | 2010-02-24 |
Family
ID=40347971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080105605A AR069860A1 (es) | 2007-12-21 | 2008-12-19 | Metodo para purificar un anticuerpo cd20 |
Country Status (15)
Country | Link |
---|---|
US (1) | US20110020322A1 (es) |
EP (1) | EP2235056A1 (es) |
JP (1) | JP2011507870A (es) |
KR (1) | KR20100105720A (es) |
CN (1) | CN101945890A (es) |
AR (1) | AR069860A1 (es) |
AU (1) | AU2008343347A1 (es) |
BR (1) | BRPI0820604A2 (es) |
CA (1) | CA2708951A1 (es) |
CL (1) | CL2008003790A1 (es) |
IL (1) | IL206227A0 (es) |
PE (1) | PE20091337A1 (es) |
RU (1) | RU2010130467A (es) |
TW (1) | TW200932758A (es) |
WO (1) | WO2009085765A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2544865C (en) | 2003-11-05 | 2019-07-09 | Glycart Biotechnology Ag | Cd20 antibodies with increased fc receptor binding affinity and effector function |
TW201014605A (en) | 2008-09-16 | 2010-04-16 | Genentech Inc | Methods for treating progressive multiple sclerosis |
CN101577344B (zh) * | 2009-06-11 | 2011-04-20 | 珠海银通交通能源投资有限公司 | 动力电池 |
KR101844859B1 (ko) | 2009-08-06 | 2018-05-18 | 제넨테크, 인크. | 단백질 정제 시의 바이러스 제거의 개선방법 |
IN2014DN09097A (es) * | 2012-05-11 | 2015-05-22 | Novartis Ag | |
EP2864346B1 (en) * | 2012-06-21 | 2018-10-17 | Synthon Biopharmaceuticals B.V. | Method of purifying an antibody |
US10293106B2 (en) * | 2013-04-03 | 2019-05-21 | Becton, Dickinson And Company | Intravenous tubing set modified for in-line catheter flushing |
KR101569783B1 (ko) | 2013-06-05 | 2015-11-19 | 한화케미칼 주식회사 | 항체의 정제 방법 |
UA120753C2 (uk) | 2013-12-17 | 2020-02-10 | Дженентек, Інк. | Біспецифічне антитіло до сd3 та cd20 |
AR101846A1 (es) | 2014-09-12 | 2017-01-18 | Genentech Inc | Anticuerpos anti-cll-1 e inmunoconjugados |
TW201718647A (zh) | 2015-06-16 | 2017-06-01 | 建南德克公司 | 抗-cll-1抗體及使用方法 |
EP3541843A1 (en) | 2016-11-15 | 2019-09-25 | Genentech, Inc. | Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies |
WO2018106959A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
US20210138213A1 (en) | 2017-03-30 | 2021-05-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
CA3089287A1 (en) | 2018-02-08 | 2019-08-15 | Genentech, Inc. | Bispecific antigen-binding molecules and methods of use |
US20230009902A1 (en) | 2018-06-20 | 2023-01-12 | Progenity, Inc. | Treatment of a disease or condition in a tissue orginating from the endoderm |
US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
KR20210095165A (ko) | 2018-11-19 | 2021-07-30 | 프로제너티, 인크. | 바이오의약품으로 질환을 치료하기 위한 방법 및 디바이스 |
EP4309722A2 (en) | 2019-12-13 | 2024-01-24 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
IT202100004496A1 (it) | 2021-02-25 | 2022-08-25 | Univ Della Calabria | Recupero di farmaci biologici o loro frammenti da soluzioni impure mediante cristallizzazione o precipitazione con membrane |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5509070A (en) * | 1992-12-15 | 1996-04-16 | Softlock Services Inc. | Method for encouraging purchase of executable and non-executable software |
US6134659A (en) * | 1998-01-07 | 2000-10-17 | Sprong; Katherine A. | Controlled usage software |
EP2325205A3 (en) * | 2000-12-28 | 2011-10-12 | Altus Pharmaceuticals Inc. | Crystals of whole antibodies and fragments thereof and methods for making and using them |
DOP2006000029A (es) * | 2005-02-07 | 2006-08-15 | Genentech Inc | Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas) |
-
2008
- 2008-12-16 AU AU2008343347A patent/AU2008343347A1/en not_active Abandoned
- 2008-12-16 EP EP08867242A patent/EP2235056A1/en not_active Withdrawn
- 2008-12-16 RU RU2010130467/10A patent/RU2010130467A/ru not_active Application Discontinuation
- 2008-12-16 BR BRPI0820604A patent/BRPI0820604A2/pt not_active IP Right Cessation
- 2008-12-16 CA CA2708951A patent/CA2708951A1/en not_active Abandoned
- 2008-12-16 KR KR1020107016210A patent/KR20100105720A/ko not_active Application Discontinuation
- 2008-12-16 WO PCT/US2008/087008 patent/WO2009085765A1/en active Application Filing
- 2008-12-16 JP JP2010539708A patent/JP2011507870A/ja active Pending
- 2008-12-16 CN CN2008801272307A patent/CN101945890A/zh active Pending
- 2008-12-18 CL CL2008003790A patent/CL2008003790A1/es unknown
- 2008-12-19 TW TW097149900A patent/TW200932758A/zh unknown
- 2008-12-19 AR ARP080105605A patent/AR069860A1/es unknown
- 2008-12-19 PE PE2008002155A patent/PE20091337A1/es not_active Application Discontinuation
-
2010
- 2010-06-07 IL IL206227A patent/IL206227A0/en unknown
- 2010-06-17 US US12/818,017 patent/US20110020322A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PE20091337A1 (es) | 2009-09-03 |
KR20100105720A (ko) | 2010-09-29 |
CN101945890A (zh) | 2011-01-12 |
CL2008003790A1 (es) | 2010-02-05 |
TW200932758A (en) | 2009-08-01 |
EP2235056A1 (en) | 2010-10-06 |
WO2009085765A1 (en) | 2009-07-09 |
CA2708951A1 (en) | 2009-07-09 |
US20110020322A1 (en) | 2011-01-27 |
RU2010130467A (ru) | 2012-01-27 |
JP2011507870A (ja) | 2011-03-10 |
BRPI0820604A2 (pt) | 2017-05-09 |
AU2008343347A1 (en) | 2009-07-09 |
IL206227A0 (en) | 2010-12-30 |
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Legal Events
Date | Code | Title | Description |
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FB | Suspension of granting procedure |