AR049157A1 - Sintesis de pirrol -2- carbonitrilos - Google Patents

Sintesis de pirrol -2- carbonitrilos

Info

Publication number
AR049157A1
AR049157A1 ARP050101206A ARP050101206A AR049157A1 AR 049157 A1 AR049157 A1 AR 049157A1 AR P050101206 A ARP050101206 A AR P050101206A AR P050101206 A ARP050101206 A AR P050101206A AR 049157 A1 AR049157 A1 AR 049157A1
Authority
AR
Argentina
Prior art keywords
carbonitrils
pirrol
synthesis
pyrrole
solution phase
Prior art date
Application number
ARP050101206A
Other languages
English (en)
Inventor
Jean Louise Helom
Anthony Scott Pilcher
Bodgen Kazimierz Wilk
Arkadiy Zinoviy Rubezhov
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR049157A1 publication Critical patent/AR049157A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Reivindicacion1: Un proceso para preparar un pirrol-2-carbonitrilo que comprende : (a) hacer reaccionar un pirrol con isocianato de clorosulfonilo en presencia de un disolvente; (b) poner en contacto el producto de la etapa (a) con un exceso molar de una N, N-dialquilformamida; (c) poner en contacto el producto de la etapa (b) con un exceso molar de una base orgánica dando como resultado la produccion de un precipitado y una fase de solucion; (d) separar el precipitado de la fase de solucion y (e) aislar un pirrol-2-carbonitrilo de la fase solucion de la etapa (d).
ARP050101206A 2004-03-30 2005-03-30 Sintesis de pirrol -2- carbonitrilos AR049157A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55780704P 2004-03-30 2004-03-30
US11/086,061 US7399870B2 (en) 2004-03-30 2005-03-22 Synthesis of pyrrole-2-carbonitriles

Publications (1)

Publication Number Publication Date
AR049157A1 true AR049157A1 (es) 2006-07-05

Family

ID=34963600

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050101206A AR049157A1 (es) 2004-03-30 2005-03-30 Sintesis de pirrol -2- carbonitrilos

Country Status (22)

Country Link
US (1) US7399870B2 (es)
EP (1) EP1730109B1 (es)
JP (2) JP5068642B2 (es)
KR (1) KR20070009654A (es)
AR (1) AR049157A1 (es)
AT (1) ATE402145T1 (es)
AU (1) AU2005230896A1 (es)
BR (1) BRPI0509317B1 (es)
CA (1) CA2560964C (es)
CR (1) CR8641A (es)
DE (1) DE602005008408D1 (es)
DK (1) DK1730109T3 (es)
EC (1) ECSP066897A (es)
ES (1) ES2310817T3 (es)
HN (1) HN2005000134A (es)
IL (1) IL178184A0 (es)
NO (1) NO20064891L (es)
PE (1) PE20060203A1 (es)
PL (1) PL1730109T3 (es)
RU (1) RU2006134013A (es)
TW (1) TW200604166A (es)
WO (1) WO2005097743A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008341138A1 (en) * 2007-12-20 2009-07-02 Teva Women's Health, Inc. Dosage regimens and pharmaceutical compositions and packages for emergency contraception
JP5754768B2 (ja) * 2011-03-10 2015-07-29 学校法人明治大学 芳香族へテロ環化合物のニトリル化物の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3506642A1 (de) * 1985-02-26 1986-08-28 A. Nattermann & Cie GmbH, 5000 Köln Neue pyrrolamidine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US5204332A (en) * 1988-12-05 1993-04-20 American Cyanamid Company Pyrrole carbonitrile and nitropyrrole insecticidal and acaricidal and molluscicidal agents
KR20000047461A (ko) * 1998-12-29 2000-07-25 성재갑 트롬빈 억제제

Also Published As

Publication number Publication date
PL1730109T3 (pl) 2008-10-31
BRPI0509317A (pt) 2007-09-04
JP5068642B2 (ja) 2012-11-07
AU2005230896A1 (en) 2005-10-20
RU2006134013A (ru) 2008-05-10
NO20064891L (no) 2006-10-26
US7399870B2 (en) 2008-07-15
US20050222432A1 (en) 2005-10-06
EP1730109B1 (en) 2008-07-23
ECSP066897A (es) 2006-11-24
PE20060203A1 (es) 2006-03-30
TW200604166A (en) 2006-02-01
KR20070009654A (ko) 2007-01-18
CA2560964C (en) 2012-10-30
HN2005000134A (es) 2007-03-26
DE602005008408D1 (en) 2008-09-04
BRPI0509317B1 (pt) 2014-04-29
ATE402145T1 (de) 2008-08-15
EP1730109A1 (en) 2006-12-13
WO2005097743A1 (en) 2005-10-20
CA2560964A1 (en) 2005-10-20
JP2007531748A (ja) 2007-11-08
JP2012158599A (ja) 2012-08-23
ES2310817T3 (es) 2009-01-16
IL178184A0 (en) 2006-12-31
CR8641A (es) 2007-08-28
DK1730109T3 (da) 2008-09-29

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