AR027636A1 - Inhibidor de la actividad de la alfa-amilasa - Google Patents

Inhibidor de la actividad de la alfa-amilasa

Info

Publication number
AR027636A1
AR027636A1 ARP010101126A ARP010101126A AR027636A1 AR 027636 A1 AR027636 A1 AR 027636A1 AR P010101126 A ARP010101126 A AR P010101126A AR P010101126 A ARP010101126 A AR P010101126A AR 027636 A1 AR027636 A1 AR 027636A1
Authority
AR
Argentina
Prior art keywords
alpha
amylase activity
inhibitor
fraction
subjected
Prior art date
Application number
ARP010101126A
Other languages
English (en)
Original Assignee
Yakult Honsha Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yakult Honsha Kk filed Critical Yakult Honsha Kk
Publication of AR027636A1 publication Critical patent/AR027636A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Polymers & Plastics (AREA)
  • Hematology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Zoology (AREA)
  • Medical Informatics (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Se refiere a un inhibidor de la actividad de la alfa-amilasa que contiene, como un componente efectivo, polifenoles obtenidos a través del siguienteproceso: hojas de guayaba y/o el fruto de la guayaba se someten a extraccion con uno o más solventes s eleccionados de entre agua y solventes hidrofílicos; elextracto resultante se somete a ultrafiltracion, para remover de tal modo sustancias que presentan un peso molecular inferior a 5,000; la fraccion restante sesomete a cromatografía hidrofobica em pleando un relleno de conduccion grupo butilo como una fase estacionaria, donde la fraccion se somete a elucion a unavelocidad de flujo de 1 mL/minuto con el uso de una solucion acuosa de dihidrogenfosfato de sodio (0,02 mol/L) y una solucion acuosa de fosfato de sodio (0,02mol/L) bajo un gradiente de concentracion entre las dos soluciones; y una fraccion de la sustancia elutada se recupera, dicha fraccion corresponde al tercerunico pico de una curva de elucion que se obtiene cuando la absorbenc ia de la sustancia se mide a 260 nm. La presente invencion se refiere también a uninhibidor de la actividad de la alfa-amilasa que contiene, como un componente efectivo, polifenoles que presentan propiedades fisioquímicas específicas, y aalimentos y bebidas que contienen el inhibidor de la actividad de la alfa-amilasa. El inhibidor de la actividad de la alfa-amilasa exhibe una actividadnotablemente excelente de la actividad inhibitoria de la alfa-amilasa comparada con el extracto de guayaba. Por consiguiente, los alimentos y bebidas quecontienen el inhibidor de la actividad de la alfa-amilasa son alimentos y bebidas dietéticos apropiados para aquellas personas con elevado nivel de azucar ensangre o hiperlipidemia.
ARP010101126A 2000-03-10 2001-03-09 Inhibidor de la actividad de la alfa-amilasa AR027636A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000066896 2000-03-10

Publications (1)

Publication Number Publication Date
AR027636A1 true AR027636A1 (es) 2003-04-02

Family

ID=18586179

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP010101126A AR027636A1 (es) 2000-03-10 2001-03-09 Inhibidor de la actividad de la alfa-amilasa
ARP080104455A AR068851A2 (es) 2000-03-10 2008-10-10 Una composicion que comprende un inhibidor de la actividad de la alfa - amilasa , un alimento o bebida que la comprenden y un metodo para producir un alimento o bebida dieteticos que la comprenden

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP080104455A AR068851A2 (es) 2000-03-10 2008-10-10 Una composicion que comprende un inhibidor de la actividad de la alfa - amilasa , un alimento o bebida que la comprenden y un metodo para producir un alimento o bebida dieteticos que la comprenden

Country Status (13)

Country Link
US (1) US7037536B2 (es)
EP (1) EP1262543B1 (es)
JP (1) JP5354833B2 (es)
KR (1) KR20020086503A (es)
CN (1) CN1264978C (es)
AR (2) AR027636A1 (es)
AU (2) AU4107801A (es)
BR (1) BRPI0108957B1 (es)
CA (1) CA2402893C (es)
ES (1) ES2393667T3 (es)
MX (1) MXPA02008819A (es)
TW (1) TWI261497B (es)
WO (1) WO2001066714A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
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JP4776149B2 (ja) * 2003-03-28 2011-09-21 クラシエフーズ株式会社 糖質吸収抑制剤および食品
EP1781116A4 (en) * 2004-06-04 2009-07-29 Horizon Science Pty Ltd NATURAL SWEETENER
JP2005350375A (ja) * 2004-06-09 2005-12-22 Kikkoman Corp 血中尿酸値低下剤
JP2006056793A (ja) * 2004-08-18 2006-03-02 Bizen Chemical Co Ltd ポリフェノール含有生成物の製造方法、ポリフェノール含有生成物、α−アミラーゼ阻害剤、抗酸化剤および食用組成物
JP2006056850A (ja) * 2004-08-23 2006-03-02 Suntory Ltd リパーゼ阻害剤
JP2006104181A (ja) * 2004-09-13 2006-04-20 Takahiro Tsujita ブナ科植物由来の糖質分解酵素阻害物質、及びその用途
JP4658560B2 (ja) * 2004-10-06 2011-03-23 備前化成株式会社 更年期障害の改善・治療剤および前立腺ガンおよび乳ガンの予防・治療剤
CN1309826C (zh) * 2004-10-27 2007-04-11 北京北大维信生物科技有限公司 纳豆激酶纯化工艺
US8021697B2 (en) * 2005-06-03 2011-09-20 Horizon Science Pty. Ltd. Substances having body mass redistribution properties
US20090074897A1 (en) * 2005-07-12 2009-03-19 Kabushiki Kaisha Yakult Honsha Agent for elevating adiponectin concentration
US20090004270A1 (en) * 2006-01-06 2009-01-01 Amerilab Technologies, Inc. Method of using guava extract
US7611739B2 (en) * 2006-01-06 2009-11-03 Amerilab Technologies, Inc. Method of using guava extract and composition including guava extract
TWI386168B (zh) * 2006-05-18 2013-02-21 Yakult Honsha Kk 番石榴葉萃取物粉末及其製造方法
JP2006298937A (ja) * 2006-07-14 2006-11-02 Kinji Ishida 肥満防止改善組成物およびそれを用いた飲食品
AU2007299581B2 (en) * 2006-09-19 2011-04-28 Poly Gain Pte Ltd Extracts derived from sugar cane and a process for their manufacture
GB0719542D0 (en) * 2007-10-08 2007-11-14 Barry Callebaut Ag Use of cocoa extract
GB0719545D0 (en) * 2007-10-08 2007-11-14 Barry Callebaut Ag Novel use of cocoa extract
GB0719544D0 (en) * 2007-10-08 2007-11-14 Barry Callebaut Ag Cocoa extract and use thereof
US20080293644A1 (en) * 2007-04-27 2008-11-27 Thomas Eidenberger Guava extract
CN102127508B (zh) * 2010-12-25 2013-01-16 浙江工业大学 α-淀粉酶抑制剂产生菌及其筛选方法
US9572852B2 (en) 2011-02-08 2017-02-21 The Product Makers (Australia) Pty Ltd Sugar extracts
WO2013133685A1 (en) 2012-03-09 2013-09-12 Biotropics Malaysia Berhad Extract formulations of rhodamnia cinerea and uses thereof
MY171216A (en) 2012-08-28 2019-10-02 The Product Makers Australia Pty Ltd Extraction method
AU2014306366B9 (en) 2013-08-16 2020-03-26 Poly Gain Pte Ltd Sugar cane derived extracts and methods of treatment
CN107213203B (zh) * 2017-06-14 2021-01-05 广东番石榴健康产业有限公司 一种从番石榴叶中提取总多酚的方法
CN107807102A (zh) * 2017-11-02 2018-03-16 威海百合生物技术股份有限公司 一种α‑淀粉酶抑制剂活性的检测方法
CN111504997B (zh) * 2020-05-15 2022-10-18 吉林鑫水科技开发有限公司 玉蜀黍须和秸秆成分提取及各成分体外降糖活性检验方法
CN111568969B (zh) * 2020-06-08 2023-05-09 广西壮族自治区中国科学院广西植物研究所 以多聚体多酚为主的荔枝皮提取物在制备α-淀粉酶抑制剂中的应用
CN113884605B (zh) * 2021-10-14 2023-06-16 安徽科技学院 一种土壤酚类物质用分级式高效分离纯化方法
CN114209057A (zh) * 2021-11-30 2022-03-22 瀚科(浙江)生物科技有限责任公司 一种刺梨天然纳米颗粒及其提取方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5429599B2 (es) * 1974-12-28 1979-09-25
JPS6036746B2 (ja) 1983-09-06 1985-08-22 備前化成株式会社 グアバ葉エキスからなる健康飲料
JP3018013B2 (ja) * 1989-10-19 2000-03-13 三井農林株式会社 α―アミラーゼ活性阻害剤
JP2670742B2 (ja) * 1993-08-21 1997-10-29 備前化成株式会社 α−アミラーゼ阻害物質
US5554645A (en) * 1994-10-03 1996-09-10 Mars, Incorporated Antineoplastic cocoa extracts and methods for making and using the same
IT1275905B1 (it) * 1995-03-14 1997-10-24 Indena Spa Frazioni polifenoliche di te', loro uso e formulazioni che le contengono
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JP2974946B2 (ja) * 1995-09-26 1999-11-10 株式会社ヤクルト本社 グアバ茶飲料
US6294190B1 (en) * 1995-12-26 2001-09-25 Suntory Limited Antiobestic agent containing procyanidin as the active ingredient
JP4109731B2 (ja) * 1997-01-23 2008-07-02 備前化成株式会社 改良グアバ葉エキス抽出法
US5912363A (en) * 1997-08-29 1999-06-15 Interhealth Nutraceuticals Method for extraction of proanthocyanidins from plant material

Also Published As

Publication number Publication date
KR20020086503A (ko) 2002-11-18
AU4107801A (en) 2001-09-17
CN1264978C (zh) 2006-07-19
MXPA02008819A (es) 2003-02-12
BR0108957A (pt) 2002-12-24
WO2001066714A1 (fr) 2001-09-13
CA2402893C (en) 2011-01-18
BRPI0108957B1 (pt) 2016-05-17
AU2001241078B2 (en) 2006-02-09
AR068851A2 (es) 2009-12-09
EP1262543B1 (en) 2012-10-24
US20030124208A1 (en) 2003-07-03
CA2402893A1 (en) 2002-09-10
EP1262543A1 (en) 2002-12-04
ES2393667T3 (es) 2012-12-27
CN1416464A (zh) 2003-05-07
EP1262543A4 (en) 2008-12-31
US7037536B2 (en) 2006-05-02
TWI261497B (en) 2006-09-11
JP5354833B2 (ja) 2013-11-27

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