AR022510A1 - Formulaciones de vacunas contra el papilomavirus humano - Google Patents
Formulaciones de vacunas contra el papilomavirus humanoInfo
- Publication number
- AR022510A1 AR022510A1 ARP000100495A ARP000100495A AR022510A1 AR 022510 A1 AR022510 A1 AR 022510A1 AR P000100495 A ARP000100495 A AR P000100495A AR P000100495 A ARP000100495 A AR P000100495A AR 022510 A1 AR022510 A1 AR 022510A1
- Authority
- AR
- Argentina
- Prior art keywords
- formulations
- against human
- vaccines against
- salt
- human papilomavirus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
Unas nuevas formulaciones de vacuna contra el papiloma virus humano (HPV) presentan una acrecentada estabilidad a largo plazo. Los componentes de laformulacion pueden incluir: partículas similares a virus (VLPs) absorbidas sobre aluminio, una sal, unsurfactante no ionico, y un tampon. Las formulacionesadicionales también contienen un estabilizante polimérico polianionico y una sal, sea en la presencia sea en la ausencia de agentes tamponantes y de detergenteno-ionico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11872399P | 1999-02-05 | 1999-02-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR022510A1 true AR022510A1 (es) | 2002-09-04 |
Family
ID=22380362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000100495A AR022510A1 (es) | 1999-02-05 | 2000-02-04 | Formulaciones de vacunas contra el papilomavirus humano |
Country Status (15)
Country | Link |
---|---|
US (1) | US6251678B1 (es) |
EP (1) | EP1150712B1 (es) |
JP (2) | JP4841726B2 (es) |
KR (1) | KR20010093290A (es) |
AR (1) | AR022510A1 (es) |
AT (1) | ATE413188T1 (es) |
AU (1) | AU764138B2 (es) |
CA (1) | CA2361837C (es) |
CY (1) | CY1108702T1 (es) |
DE (1) | DE60040727D1 (es) |
DK (1) | DK1150712T3 (es) |
ES (1) | ES2313881T3 (es) |
PT (1) | PT1150712E (es) |
SI (1) | SI1150712T1 (es) |
WO (1) | WO2000045841A2 (es) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA982950B (en) * | 1997-04-08 | 1998-10-19 | Merck & Co Inc | Stabilized human papillomavirus formulations |
GB9921146D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
US7456009B2 (en) | 2000-03-07 | 2008-11-25 | Merck & Co., Inc. | Adenovirus formulations |
JP5118798B2 (ja) * | 2000-03-07 | 2013-01-16 | メルク・シャープ・エンド・ドーム・コーポレイション | アデノウイルス製剤 |
WO2002013860A1 (fr) * | 2000-08-11 | 2002-02-21 | Chugai Seiyaku Kabushiki Kaisha | Preparations stabilisees contenant un anticorps |
CA2327950A1 (en) * | 2000-12-08 | 2002-06-08 | Groupe Minutia Inc. | Grain refining agent for cast aluminum or magnesium products |
GB0118249D0 (en) * | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
DE10137102A1 (de) | 2001-07-30 | 2003-02-27 | Deutsches Krebsforsch | Polyvalente Vakzine gegen durch Papillomaviren verursachte Erkrankungen, Verfahren zu deren Herstellung und deren Verwendung |
MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
PL371261A1 (en) * | 2002-01-18 | 2005-06-13 | Schering Aktiengesellschaft | Stabilized formulations of adenovirus |
AU2003219760A1 (en) * | 2002-02-14 | 2003-09-04 | Novavax, Inc. | Optimization of gene sequences of virus-like particles for expression in insect cells |
GB0206360D0 (en) * | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
AP2005003347A0 (en) * | 2002-12-20 | 2005-06-30 | Glayosmithkline Biolog S A | HPV-16 and-18 Lu VLP vaccine |
US7858098B2 (en) * | 2002-12-20 | 2010-12-28 | Glaxosmithkline Biologicals, S.A. | Vaccine |
JP2007001865A (ja) * | 2003-09-16 | 2007-01-11 | Ltt Bio-Pharma Co Ltd | 脂溶性薬物封入微粒子、その製造法およびそれを含有する製剤 |
US7608278B2 (en) | 2003-12-30 | 2009-10-27 | Wyeth | Formulations of hydrophobic proteins in an immunogenic composition having improved tolerability |
US7758866B2 (en) * | 2004-06-16 | 2010-07-20 | Glaxosmithkline Biologicals, S.A. | Vaccine against HPV16 and HPV18 and at least another HPV type selected from HPV 31, 45 or 52 |
CA2588274A1 (en) * | 2004-10-05 | 2006-04-13 | Cytos Biotechnology Ag | Vlp-antigen conjugates and their uses as vaccines |
MX2007003954A (es) * | 2004-10-05 | 2007-06-14 | Cytos Biotechnology Ag | Conjugados de antigeno de particula tipo virus y su uso como vacunas. |
JP4182074B2 (ja) * | 2005-03-03 | 2008-11-19 | ファナック株式会社 | ハンド及びハンドリングロボット |
CA2600036A1 (en) * | 2005-03-04 | 2006-09-14 | Dynavax Technologies Corporation | Vaccines comprising oligonucleotides having immunostimulatory sequences (iss) wherein the iss are conjugated to antigens and stabilized by buffer conditions and further excipients |
AU2006236905B2 (en) | 2005-04-15 | 2010-06-03 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for producing an enhanced immune response to a human papillomavirus immunogen |
DK2066354T3 (da) | 2006-09-29 | 2013-05-27 | Ligocyte Pharmaceuticals Inc | Norovirus vaccine formuleringer |
ES2673823T3 (es) * | 2006-11-03 | 2018-06-25 | Alphavax, Inc. | Formulaciones de alfavirus y de partículas de replicones de alfavirus y métodos relacionados |
EP2129394B1 (en) * | 2007-03-09 | 2012-06-20 | Merck Sharp & Dohme Corp. | Papillomavirus vaccine compositions |
US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
JP2010539192A (ja) | 2007-09-18 | 2010-12-16 | リゴサイト ファーマスーティカルズ,インコーポレイテッド | ノロウイルスに対して防御免疫応答を付与する方法 |
EP2258380B1 (en) | 2008-03-31 | 2013-03-13 | Morinaga Milk Industry Co., Ltd. | Nucleic acid for imparting heat resistance to lactoferrin |
WO2011079260A2 (en) * | 2009-12-23 | 2011-06-30 | Arizona Board Of Regents Acting For And On Behalf Of Arizona State University | Stabilized virus like particles having enhanced mucosal immunogenicity |
HRP20210242T4 (hr) | 2010-08-23 | 2024-05-10 | Wyeth Llc | Stabilne formulacije antigena iz bakterije neisseria meningitidis rlp2086 |
CN103096920B (zh) | 2010-09-10 | 2016-03-23 | 惠氏有限责任公司 | 脑膜炎奈瑟球菌orf2086抗原的非脂质化变体 |
US20130259948A1 (en) | 2010-09-21 | 2013-10-03 | National Institute Of Immunology | Spray dried powder formulation for vaccines entrapping alum and the antigen in biodegradable polymer particles |
RU2610174C2 (ru) * | 2011-06-24 | 2017-02-08 | Мерк Шарп И Доум Корп. | Вакцинные составы против вируса папилломы человека (hpv), содержащие алюминиевый адъювант, и способы их получения |
JP6208659B2 (ja) | 2011-07-11 | 2017-10-04 | タケダ ワクチン,インコーポレイテッド | 非経口ノロウイルスワクチン製剤 |
TWI570240B (zh) * | 2011-09-09 | 2017-02-11 | 默沙東公司 | 作為細胞巨大病毒疫苗之條件式複製cmv |
EP2802649B1 (en) | 2012-01-09 | 2017-08-09 | Sanofi Pasteur Biologics, LLC | Purification of herpes virus |
BR122016004924A2 (pt) | 2012-03-09 | 2019-07-30 | Pfizer Inc. | Polipeptídeo isolado e composições imunogênicas compreendendo os mesmos |
SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
WO2013177172A2 (en) * | 2012-05-21 | 2013-11-28 | Sanofi Pasteur Limited | Herpesvirus compositions and related methods |
CN104379170B (zh) | 2012-06-20 | 2017-05-03 | 国立大学法人东京大学 | 粘膜免疫刺激剂及hpv感染症治疗用经口药物组合物 |
WO2014100860A2 (en) * | 2012-12-28 | 2014-07-03 | Cellestis Limited | A cell mediated immune response assay |
JP6446377B2 (ja) | 2013-03-08 | 2018-12-26 | ファイザー・インク | 免疫原性融合ポリペプチド |
US9254332B2 (en) * | 2013-03-15 | 2016-02-09 | Arecor Limited | Stable aqueous formulations of adenovirus vectors |
CA2923129C (en) | 2013-09-08 | 2020-06-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
EP3100049B1 (en) | 2014-01-31 | 2019-11-06 | Ulisse Biomed S.R.L. | Biosensors for the detection of infection and associated maladies |
CN104479892A (zh) * | 2014-11-06 | 2015-04-01 | 王越 | 一种具有植物杀菌功能洗衣液的制备方法 |
AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
CA3019515A1 (en) | 2016-04-01 | 2017-10-05 | Colorado State University Research Foundation | Compositions and methods for enhanced innate immunity |
AU2018215585B2 (en) | 2017-01-31 | 2022-03-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
CA3079828A1 (en) * | 2017-11-01 | 2019-05-09 | Merck Sharp & Dohme Corp. | Stable formulations of cytomegalovirus |
WO2024111566A1 (ja) * | 2022-11-22 | 2024-05-30 | 一般財団法人阪大微生物病研究会 | 安定化されたvlpワクチン |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9320782D0 (en) * | 1993-10-08 | 1993-12-01 | Univ Leeds Innovations Ltd | Stabilising of proteins on solution |
AUPM322393A0 (en) | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
US5569468A (en) * | 1994-02-17 | 1996-10-29 | Modi; Pankaj | Vaccine delivery system for immunization, using biodegradable polymer microspheres |
PL183781B1 (pl) * | 1994-05-16 | 2002-07-31 | Merck & Co Inc | Sposób wytwarzania szczepionki przeciwko ludzkiemu wirusowi brodawczaków |
AUPM566794A0 (en) | 1994-05-17 | 1994-06-09 | University Of Queensland, The | Process and product |
AR004464A1 (es) | 1994-11-14 | 1998-12-16 | Merck Sharp & Dohme | Un metodo para producir una proteina de capside de papilomavirus |
IL117459A (en) | 1995-03-22 | 2005-11-20 | Merck & Co Inc | Dna encoding human papillomavirus type 18 |
IL117591A0 (en) | 1995-03-30 | 1996-07-23 | Merck & Co Inc | Synthetic DNA encoding human papillomavirus type 11 L1 protein |
EP0939648B1 (en) * | 1996-09-26 | 2007-11-07 | Merck & Co., Inc. | Rotavirus vaccine formulations |
ATE470434T1 (de) * | 1997-02-06 | 2010-06-15 | Merck Sharp & Dohme | Thimerosal-freie konservierungsmittel für impfstoffe |
KR20010006169A (ko) * | 1997-04-08 | 2001-01-26 | 폴락 돈나 엘. | 안정화된 사람 파필로마바이러스 제형물 |
-
2000
- 2000-02-01 DK DK00905886T patent/DK1150712T3/da active
- 2000-02-01 ES ES00905886T patent/ES2313881T3/es not_active Expired - Lifetime
- 2000-02-01 SI SI200031009T patent/SI1150712T1/sl unknown
- 2000-02-01 KR KR1020017009504A patent/KR20010093290A/ko not_active Application Discontinuation
- 2000-02-01 AU AU27492/00A patent/AU764138B2/en not_active Expired
- 2000-02-01 JP JP2000596960A patent/JP4841726B2/ja not_active Expired - Lifetime
- 2000-02-01 EP EP00905886A patent/EP1150712B1/en not_active Expired - Lifetime
- 2000-02-01 AT AT00905886T patent/ATE413188T1/de active
- 2000-02-01 CA CA2361837A patent/CA2361837C/en not_active Expired - Lifetime
- 2000-02-01 PT PT00905886T patent/PT1150712E/pt unknown
- 2000-02-01 DE DE60040727T patent/DE60040727D1/de not_active Expired - Lifetime
- 2000-02-01 WO PCT/US2000/002463 patent/WO2000045841A2/en active IP Right Grant
- 2000-02-02 US US09/496,812 patent/US6251678B1/en not_active Expired - Lifetime
- 2000-02-04 AR ARP000100495A patent/AR022510A1/es unknown
-
2009
- 2009-01-15 CY CY20091100051T patent/CY1108702T1/el unknown
-
2011
- 2011-05-31 JP JP2011121539A patent/JP2011225578A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
US6251678B1 (en) | 2001-06-26 |
DE60040727D1 (de) | 2008-12-18 |
ES2313881T3 (es) | 2009-03-16 |
AU764138B2 (en) | 2003-08-14 |
JP4841726B2 (ja) | 2011-12-21 |
CA2361837C (en) | 2011-06-07 |
JP2002536340A (ja) | 2002-10-29 |
DK1150712T3 (da) | 2009-02-02 |
AU2749200A (en) | 2000-08-25 |
JP2011225578A (ja) | 2011-11-10 |
CA2361837A1 (en) | 2000-08-10 |
ATE413188T1 (de) | 2008-11-15 |
PT1150712E (pt) | 2008-12-22 |
WO2000045841A2 (en) | 2000-08-10 |
EP1150712A2 (en) | 2001-11-07 |
CY1108702T1 (el) | 2013-09-04 |
EP1150712B1 (en) | 2008-11-05 |
KR20010093290A (ko) | 2001-10-27 |
WO2000045841A3 (en) | 2000-12-14 |
SI1150712T1 (sl) | 2009-02-28 |
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