AR014062A1 - COMPOSICION DE METILFENIDATO PARA APLICACIoN TOPICA Y METODO PARA SU PREPARACION - Google Patents
COMPOSICION DE METILFENIDATO PARA APLICACIoN TOPICA Y METODO PARA SU PREPARACIONInfo
- Publication number
- AR014062A1 AR014062A1 ARP980106392A ARP980106392A AR014062A1 AR 014062 A1 AR014062 A1 AR 014062A1 AR P980106392 A ARP980106392 A AR P980106392A AR P980106392 A ARP980106392 A AR P980106392A AR 014062 A1 AR014062 A1 AR 014062A1
- Authority
- AR
- Argentina
- Prior art keywords
- methylphenidate
- composition
- topical application
- patient
- attention deficit
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Un método para el tratamiento del trastorno del deficit de atencion (ADD) y deficit de atencion con hiperactividad (ADHD). Estos trastornos sontratados por la aplicacion topica de una composicion que comprende metilfenidato a unpaciente que la necesita. Esta composicion está en unsistema flexible y limitado donde está presente el metilfenidato en una cantidad suficiente para alcanzar una cinética prácticamente de orden ceropara la administracion a la piel o las mucosas de un paciente durante un período de por lo menos 10 horas. La figura que se acompana demuestrasustancialmente entregas cinéticas de orden de cero en dos de los estudios representativos, como se demuestra por los perfiles de flujo relativamentehorizontales de los niveles de metilfenidato en sangre. En una realiacion, la composicion es preparada en forma de parche y, además, comprende unadhesivo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6951097P | 1997-12-15 | 1997-12-15 | |
US09/163,351 US6210705B1 (en) | 1997-12-15 | 1998-09-30 | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
Publications (1)
Publication Number | Publication Date |
---|---|
AR014062A1 true AR014062A1 (es) | 2001-01-31 |
Family
ID=26750154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980106392A AR014062A1 (es) | 1997-12-15 | 1998-12-15 | COMPOSICION DE METILFENIDATO PARA APLICACIoN TOPICA Y METODO PARA SU PREPARACION |
Country Status (28)
Country | Link |
---|---|
US (2) | US6210705B1 (es) |
EP (2) | EP1037615B1 (es) |
JP (3) | JP4316800B2 (es) |
KR (1) | KR100633348B1 (es) |
CN (1) | CN1368876A (es) |
AR (1) | AR014062A1 (es) |
AT (1) | ATE260652T1 (es) |
AU (1) | AU752027B2 (es) |
BR (1) | BR9814282A (es) |
CA (1) | CA2315237C (es) |
CZ (2) | CZ2009132A3 (es) |
DE (1) | DE69822199T2 (es) |
DK (1) | DK1037615T3 (es) |
ES (2) | ES2219926T3 (es) |
HK (2) | HK1049447A1 (es) |
HU (1) | HU226615B1 (es) |
IL (1) | IL136760A0 (es) |
LV (1) | LV12558B (es) |
NO (1) | NO329974B1 (es) |
NZ (1) | NZ505689A (es) |
PE (1) | PE20000120A1 (es) |
PL (1) | PL195315B1 (es) |
PT (1) | PT1037615E (es) |
RU (1) | RU2233156C2 (es) |
SI (1) | SI20360B (es) |
TR (1) | TR200001736T2 (es) |
TW (2) | TWI242452B (es) |
WO (1) | WO1999030694A2 (es) |
Families Citing this family (65)
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US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
US20020102291A1 (en) * | 1997-12-15 | 2002-08-01 | Noven Pharmaceuticals, Inc. | Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
GB9913458D0 (en) * | 1999-06-09 | 1999-08-11 | Medeva Europ Ltd | The therapeutic use of d-threo-methylphenidate |
GB9918735D0 (en) * | 1999-08-09 | 1999-10-13 | Straken Limited | Transdermal patches |
CO5261532A1 (es) * | 1999-11-15 | 2003-03-31 | Novartis Ag | Compuestos heterociclicos sililados, procedimiento para la preparacion de estos y composicion farmaceutica que los contiene |
ATE252903T1 (de) * | 1999-12-17 | 2003-11-15 | Celltech Pharma Europ Ltd | Arzneimittel zur behandlung konvulsivischer zustände |
US6455066B1 (en) | 2000-03-10 | 2002-09-24 | Epicept Corporation | Intradermal-penetration agents for topical local anesthetic administration |
US6905016B2 (en) * | 2000-03-14 | 2005-06-14 | Noven Pharmaceuticals, Inc. | Packaging system for transdermal drug delivery systems |
US7674480B2 (en) * | 2000-06-23 | 2010-03-09 | Teva Pharmaceutical Industries Ltd. | Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition |
US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
DE10060550C1 (de) * | 2000-12-06 | 2002-04-18 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit dem Wirkstoff Oxybutynin und Verfahren zur Herstellung Oxybutynin enthaltender Wirkstoffschichten |
BR0207955A (pt) * | 2001-03-07 | 2004-02-25 | Hisamitsu Pharmaceutical Co | Agente de emplastro |
FR2822049B1 (fr) * | 2001-03-13 | 2003-08-01 | Dbv Medica 1 | Patch destine notamment a depister l'etat de sensibilisation d'un sujet a un allergene, procede de fabrication et utilisation |
DE20221841U1 (de) * | 2001-03-16 | 2008-05-21 | Alza Corp., Mountain View | Transdermal-Pflaster zum Verabreichen von Fentanyl |
US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
DE10141652B4 (de) * | 2001-08-24 | 2011-04-07 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung |
DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
US20030049272A1 (en) * | 2001-08-30 | 2003-03-13 | Yatindra Joshi | Pharmaceutical composition which produces irritation |
JP4354678B2 (ja) * | 2002-08-28 | 2009-10-28 | 久光製薬株式会社 | 貼付剤 |
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WO2004054542A2 (en) | 2002-12-13 | 2004-07-01 | Durect Corporation | Oral drug delivery system comprising high viscosity liquid carrier materials |
ES2626784T3 (es) * | 2003-10-28 | 2017-07-26 | Noven Pharmaceuticals, Inc. | Dispositivo de administración transdérmica de fármacos |
CA2595400C (en) * | 2005-01-20 | 2017-01-17 | Institute For Molecular Medicine, Inc. | Methylphenidate derivatives and their use in the treatment of angiogenic diseases and conditions |
ES2372004T3 (es) * | 2005-01-20 | 2012-01-12 | Institute For Molecular Medicine, Inc. | Usos de derivados de metilfenidato. |
US9393218B2 (en) * | 2005-12-23 | 2016-07-19 | Epinamics Gmbh | Use of film-forming hair care polymers from the group of polyurethanes and pharmaceutical preparations and patches that contain these polymers |
AU2007221117A1 (en) * | 2006-02-27 | 2007-09-07 | Noven Pharmaceuticals, Inc. | Transdermal therapeutic system comprising scopolamine |
EP2012745B1 (en) * | 2006-05-01 | 2010-10-27 | Colgate-Palmolive Company | Oral care composition with silicone composite |
US20100104621A1 (en) * | 2007-02-21 | 2010-04-29 | Connected Health Systems, Llc | Treating adhd and other diseases involving inflammation |
MY162831A (en) * | 2007-10-15 | 2017-07-31 | Alza Corp | Once-a-day replacement transdermal administration of fentanyl |
FR2924349B1 (fr) | 2007-12-03 | 2010-01-01 | Dbv Tech | Methode de desensibilitation aux allergenes |
FR2924350B1 (fr) * | 2007-12-03 | 2010-08-13 | Dbv Tech | Procede et compositions pour la vaccination par voie cutanee |
WO2009075782A1 (en) | 2007-12-06 | 2009-06-18 | Durect Corporation | Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition |
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FR2926466B1 (fr) * | 2008-01-23 | 2010-11-12 | Dbv Tech | Procede de fabrication de patchs par electrospray |
JP5856843B2 (ja) | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ,インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
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EP2364695A1 (en) | 2010-02-10 | 2011-09-14 | Nitto Denko Corporation | Methylphenidate patch preparation |
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US10292937B2 (en) | 2011-03-23 | 2019-05-21 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
US11241391B2 (en) | 2011-03-23 | 2022-02-08 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US8927010B2 (en) | 2011-03-23 | 2015-01-06 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
ES2644942T3 (es) | 2011-03-23 | 2017-12-01 | Ironshore Pharmaceuticals & Development, Inc. | Métodos y composiciones para el tratamiento del trastorno por déficit de atención |
US9283214B2 (en) | 2011-03-23 | 2016-03-15 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US8916588B2 (en) | 2011-03-23 | 2014-12-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods for treatment of attention deficit hyperactivity disorder |
US9119809B2 (en) | 2011-03-23 | 2015-09-01 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US10905652B2 (en) | 2011-03-23 | 2021-02-02 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9603809B2 (en) | 2011-03-23 | 2017-03-28 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
PL2736510T3 (pl) * | 2011-07-28 | 2017-07-31 | Kempharm, Inc. | Proleki metylofenidatu, procesy ich wytwarzania i stosowania |
CA2891467A1 (en) | 2012-10-15 | 2014-04-24 | Noven Pharmaceuticals, Inc. | Compositions and methods for the transdermal delivery of methylphenidate |
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ES2864327T3 (es) | 2012-12-28 | 2021-10-13 | Noven Pharma | Composiciones de múltiples polímeros para la administración transdérmica de fármacos |
US9314470B2 (en) | 2012-12-28 | 2016-04-19 | Noven Pharmaceuticals, Inc. | Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol |
US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
US11337936B2 (en) | 2013-03-14 | 2022-05-24 | Noven Pharmaceuticals, Inc. | Amphetamine transdermal compositions with acrylic block copolymer |
AR095259A1 (es) | 2013-03-15 | 2015-09-30 | Noven Pharma | Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria |
WO2014144975A1 (en) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
AR095260A1 (es) | 2013-03-15 | 2015-09-30 | Noven Pharma | Composiciones de anfetaminas transdérmicas estables y métodos de fabricación |
BR112016014236A2 (pt) | 2013-12-25 | 2017-08-08 | Fujimoto Co Ltd | Agente profilático e terapêutico para o distúrbio do déficit de atenção/hiperatividade |
US9980921B2 (en) * | 2016-06-30 | 2018-05-29 | Taho Pharmaceuticals Ltd. | Transdermal delivery system containing methylphenidate or its salts and methods thereof |
CN106511264A (zh) * | 2016-11-15 | 2017-03-22 | 北京万全德众医药生物技术有限公司 | 一种盐酸哌甲酯口服溶液剂及其制备方法 |
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1998
- 1998-09-30 US US09/163,351 patent/US6210705B1/en not_active Expired - Lifetime
- 1998-12-14 DE DE69822199T patent/DE69822199T2/de not_active Expired - Lifetime
- 1998-12-14 TR TR2000/01736T patent/TR200001736T2/xx unknown
- 1998-12-14 CA CA002315237A patent/CA2315237C/en not_active Expired - Lifetime
- 1998-12-14 TW TW087120741A patent/TWI242452B/zh not_active IP Right Cessation
- 1998-12-14 CZ CZ2009-132A patent/CZ2009132A3/cs not_active IP Right Cessation
- 1998-12-14 ES ES98963170T patent/ES2219926T3/es not_active Expired - Lifetime
- 1998-12-14 BR BR9814282-8A patent/BR9814282A/pt not_active Application Discontinuation
- 1998-12-14 SI SI9820083A patent/SI20360B/sl not_active IP Right Cessation
- 1998-12-14 CZ CZ20002209A patent/CZ300535B6/cs not_active IP Right Cessation
- 1998-12-14 TW TW092128573A patent/TWI244396B/zh not_active IP Right Cessation
- 1998-12-14 EP EP98963170A patent/EP1037615B1/en not_active Expired - Lifetime
- 1998-12-14 AT AT98963170T patent/ATE260652T1/de active
- 1998-12-14 WO PCT/US1998/026560 patent/WO1999030694A2/en active Application Filing
- 1998-12-14 IL IL13676098A patent/IL136760A0/xx not_active IP Right Cessation
- 1998-12-14 CN CN98813634A patent/CN1368876A/zh active Pending
- 1998-12-14 NZ NZ505689A patent/NZ505689A/xx not_active IP Right Cessation
- 1998-12-14 AU AU18249/99A patent/AU752027B2/en not_active Ceased
- 1998-12-14 PT PT98963170T patent/PT1037615E/pt unknown
- 1998-12-14 RU RU2000119097/15A patent/RU2233156C2/ru not_active IP Right Cessation
- 1998-12-14 PL PL98341596A patent/PL195315B1/pl unknown
- 1998-12-14 EP EP10011358.8A patent/EP2314288B1/en not_active Expired - Lifetime
- 1998-12-14 DK DK98963170T patent/DK1037615T3/da active
- 1998-12-14 HU HU0004539A patent/HU226615B1/hu not_active IP Right Cessation
- 1998-12-14 JP JP2000538677A patent/JP4316800B2/ja not_active Expired - Lifetime
- 1998-12-14 ES ES10011358.8T patent/ES2452517T3/es not_active Expired - Lifetime
- 1998-12-14 KR KR1020007006477A patent/KR100633348B1/ko not_active IP Right Cessation
- 1998-12-15 PE PE1998001219A patent/PE20000120A1/es not_active Application Discontinuation
- 1998-12-15 AR ARP980106392A patent/AR014062A1/es not_active Application Discontinuation
-
2000
- 2000-06-15 NO NO20003096A patent/NO329974B1/no not_active IP Right Cessation
- 2000-07-17 LV LVP-00-92A patent/LV12558B/en unknown
- 2000-07-18 US US09/618,626 patent/US6348211B1/en not_active Expired - Lifetime
-
2003
- 2003-03-05 HK HK03101632.9A patent/HK1049447A1/zh unknown
-
2008
- 2008-11-13 JP JP2008291364A patent/JP2009073856A/ja active Pending
-
2011
- 2011-10-20 HK HK11111285.8A patent/HK1156872A1/xx not_active IP Right Cessation
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2012
- 2012-12-26 JP JP2012282405A patent/JP2013056944A/ja active Pending
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