AR010938A1 - PROCEDURE TO PREPARE L-ASCORBIC ACID. - Google Patents
PROCEDURE TO PREPARE L-ASCORBIC ACID.Info
- Publication number
- AR010938A1 AR010938A1 ARP980103913A ARP980103913A AR010938A1 AR 010938 A1 AR010938 A1 AR 010938A1 AR P980103913 A ARP980103913 A AR P980103913A AR P980103913 A ARP980103913 A AR P980103913A AR 010938 A1 AR010938 A1 AR 010938A1
- Authority
- AR
- Argentina
- Prior art keywords
- acid
- ascorbic acid
- prepare
- procedure
- keto
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Un procedimiento para preparar ácido L-ascorbico por reaccion del ácido 2-ceto-L-gulonico con un ácido mineral concentrado, a una temperaturacomprendida entre 40 y 80°C. El procedimiento del invento permite obtener altos rendimientos de ácido L-ascorbico por lactonizacion del ácido 2-ceto-gulonicocon un ácido mineral concentrado con un menor consumo de energía y una menor contaminacion del medio ambiente. Frente a los procedimientos del estado de latécnica, el procedimiento del invento también presenta la ventaja de que permite trabajar en ausencia de disolventes orgánicos.A procedure to prepare L-ascorbic acid by reacting 2-keto-L-gulonic acid with a concentrated mineral acid, at a temperature between 40 and 80 ° C. The process of the invention allows to obtain high yields of L-ascorbic acid by lactonization of 2-keto-gulonic acid with a concentrated mineral acid with a lower energy consumption and less contamination of the environment. Compared to the state-of-the-art processes, the process of the invention also has the advantage that it allows working in the absence of organic solvents.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19734086A DE19734086C1 (en) | 1997-08-07 | 1997-08-07 | L-ascorbic acid preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR010938A1 true AR010938A1 (en) | 2000-07-12 |
Family
ID=7838185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980103913A AR010938A1 (en) | 1997-08-07 | 1998-08-07 | PROCEDURE TO PREPARE L-ASCORBIC ACID. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1001952A2 (en) |
| JP (1) | JP2001512722A (en) |
| KR (1) | KR20010022595A (en) |
| CN (1) | CN1265655A (en) |
| AR (1) | AR010938A1 (en) |
| AU (1) | AU9156298A (en) |
| BR (1) | BR9811855A (en) |
| CA (1) | CA2299364A1 (en) |
| CO (1) | CO4770883A1 (en) |
| DE (1) | DE19734086C1 (en) |
| ID (1) | ID25547A (en) |
| WO (1) | WO1999007691A2 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19904821C1 (en) * | 1999-02-05 | 2000-07-06 | Merck Patent Gmbh | Preparation of L-ascorbic acid from 2-keto- or 2,3-4,6-diacetone-2-keto-L-gulonic acid |
| DE19919203A1 (en) | 1999-04-28 | 2000-11-02 | Basf Ag | Process for the preparation of L-ascorbic acid |
| DE19954511A1 (en) | 1999-11-12 | 2001-05-17 | Basf Ag | Process for the preparation of alkali salts of L-ascorbic acid |
| DE10022518A1 (en) * | 2000-05-10 | 2001-11-15 | Basf Ag | Preparation of L-ascorbic acids by reacting 2-keto-L-gulonic acids or melt of 2-keto-L-gulonic acid alkyl esters under acid catalysis using water-miscible solvent(s) |
| WO2002051827A1 (en) | 2000-12-22 | 2002-07-04 | Eastman Chemical Company | Process for producing ascorbic acid in the presence of a sulfit |
| EP1351949B1 (en) | 2000-12-22 | 2005-05-18 | Eastman Chemical Company | Continuous process for producing l-ascorbic acid |
| WO2002083739A2 (en) * | 2001-04-10 | 2002-10-24 | Danisco Usa, Inc. | Polymerization of mono and disaccharides with monocarboxylic acids and lactones |
| US6740762B2 (en) | 2001-08-24 | 2004-05-25 | Eastman Chemical Company | Process for ascorbic acids using alkaline earth silicate catalysts |
| US6716997B1 (en) | 2001-10-09 | 2004-04-06 | Eastman Chemical Company | Systems and methods for generation of ascorbic acid with reduced color |
| CN111018815A (en) * | 2019-12-29 | 2020-04-17 | 安徽丰原发酵技术工程研究有限公司 | Method for preparing vitamin C by increasing concentration of hydrochloric acid through solvent extraction |
| CN111087373A (en) * | 2019-12-29 | 2020-05-01 | 安徽丰原发酵技术工程研究有限公司 | Method for preparing vitamin C by acid method |
| CN114369075B (en) * | 2022-02-14 | 2023-09-29 | 河北乐开节能科技股份有限公司 | Method for preparing VC crystal by using aqueous solution of 2-keto-L-gulonic acid in one step |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2462251A (en) * | 1945-05-16 | 1949-02-22 | Merck & Co Inc | Process for preparing ascorbic acids |
| DD141832A1 (en) * | 1978-10-31 | 1980-05-21 | Joachim Schmidt | METHOD AND DEVICE FOR PREPARING L-ASCORBIN ACID |
| CN86105960A (en) * | 1985-08-09 | 1987-05-13 | 鲁布里佐尔公司 | Under substantially anhydrous conditions, prepare the L-xitix from 2-ketone-L-gulonic acid |
| DE3819045C2 (en) * | 1987-06-08 | 1997-06-19 | Takeda Chemical Industries Ltd | Production of L-ascorbic acid |
-
1997
- 1997-08-07 DE DE19734086A patent/DE19734086C1/en not_active Expired - Fee Related
-
1998
- 1998-07-24 WO PCT/EP1998/004649 patent/WO1999007691A2/en not_active Application Discontinuation
- 1998-07-24 BR BR9811855-2A patent/BR9811855A/en not_active Application Discontinuation
- 1998-07-24 KR KR1020007001187A patent/KR20010022595A/en not_active Application Discontinuation
- 1998-07-24 CA CA002299364A patent/CA2299364A1/en not_active Abandoned
- 1998-07-24 JP JP2000506195A patent/JP2001512722A/en active Pending
- 1998-07-24 CN CN98807955A patent/CN1265655A/en active Pending
- 1998-07-24 EP EP98943779A patent/EP1001952A2/en not_active Withdrawn
- 1998-07-24 AU AU91562/98A patent/AU9156298A/en not_active Abandoned
- 1998-07-24 ID IDW20000174A patent/ID25547A/en unknown
- 1998-08-06 CO CO98045322A patent/CO4770883A1/en unknown
- 1998-08-07 AR ARP980103913A patent/AR010938A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999007691A2 (en) | 1999-02-18 |
| BR9811855A (en) | 2000-08-15 |
| KR20010022595A (en) | 2001-03-26 |
| CO4770883A1 (en) | 1999-04-30 |
| AU9156298A (en) | 1999-03-01 |
| CA2299364A1 (en) | 1999-02-18 |
| ID25547A (en) | 2000-10-12 |
| DE19734086C1 (en) | 1998-08-13 |
| CN1265655A (en) | 2000-09-06 |
| EP1001952A2 (en) | 2000-05-24 |
| JP2001512722A (en) | 2001-08-28 |
| WO1999007691A3 (en) | 1999-04-08 |
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