AR008765A1 - Un peptido o un derivado, analogo o variante, funcional del mismo, un peptido recombinante o sintetico del mismo, una secuencia nucleotidica y vectorque la contiene, una celula huesped transformada, un procedimiento para su preparacion, una composicion farmaceutica que lo comprende, un compuesto del - Google Patents
Un peptido o un derivado, analogo o variante, funcional del mismo, un peptido recombinante o sintetico del mismo, una secuencia nucleotidica y vectorque la contiene, una celula huesped transformada, un procedimiento para su preparacion, una composicion farmaceutica que lo comprende, un compuesto delInfo
- Publication number
- AR008765A1 AR008765A1 ARP970102432A ARP970102432A AR008765A1 AR 008765 A1 AR008765 A1 AR 008765A1 AR P970102432 A ARP970102432 A AR P970102432A AR P970102432 A ARP970102432 A AR P970102432A AR 008765 A1 AR008765 A1 AR 008765A1
- Authority
- AR
- Argentina
- Prior art keywords
- composite
- same
- peptide
- recombinant
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Child & Adolescent Psychology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Un péptido o un derivado, análogo o variante funcional del mismo, que modula el peso corporal sustancialmente por medio de modulacion de lautilizacion de la energía, un péptido recombinante o sintético del mismo, una secuencia nucleotídica yvector que la contiene, una célula huéspedtransformada, una composicion farmacéutica que contiene un compuesto de este tipo, un procedimiento para la preparacionde un compuesto de este tipo y el usode dicho compuesto en medicina.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9611775.9A GB9611775D0 (en) | 1996-06-06 | 1996-06-06 | Novel compounds |
| GBGB9618540.0A GB9618540D0 (en) | 1996-09-05 | 1996-09-05 | Novel compounds |
| GBGB9703493.8A GB9703493D0 (en) | 1997-02-20 | 1997-02-20 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR008765A1 true AR008765A1 (es) | 2000-02-23 |
Family
ID=27268305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970102432A AR008765A1 (es) | 1996-06-06 | 1997-06-04 | Un peptido o un derivado, analogo o variante, funcional del mismo, un peptido recombinante o sintetico del mismo, una secuencia nucleotidica y vectorque la contiene, una celula huesped transformada, un procedimiento para su preparacion, una composicion farmaceutica que lo comprende, un compuesto del |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0912609A2 (es) |
| JP (1) | JP2000512137A (es) |
| KR (1) | KR20000016402A (es) |
| CN (1) | CN1221426A (es) |
| AR (1) | AR008765A1 (es) |
| AU (1) | AU3337297A (es) |
| BR (1) | BR9709529A (es) |
| CA (1) | CA2257240A1 (es) |
| CZ (1) | CZ397898A3 (es) |
| IL (1) | IL127153A0 (es) |
| NO (1) | NO985683D0 (es) |
| NZ (1) | NZ332879A (es) |
| PL (1) | PL330361A1 (es) |
| TR (1) | TR199802534T2 (es) |
| WO (1) | WO1997046585A2 (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1101112B1 (en) | 1998-07-28 | 2004-10-06 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Leptin-mediated gene-induction |
| US6777388B1 (en) | 1998-08-21 | 2004-08-17 | Clf Medical Technology Acceleration Program, Inc. | Leptin-related peptides |
| US7208572B2 (en) | 1998-08-21 | 2007-04-24 | Albany Medical College | Leptin-related peptides |
| US6420339B1 (en) | 1998-10-14 | 2002-07-16 | Amgen Inc. | Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility |
| EP1214351A2 (en) * | 1999-09-22 | 2002-06-19 | Genset | Methods of screening for compounds that modulate the lsr-leptin interaction and their use in the prevention and treatment of obesity-related diseases |
| EP1612221A3 (en) | 2000-05-22 | 2008-07-23 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Receptor-based interaction trap |
| DK2219031T3 (da) | 2001-10-22 | 2013-06-17 | Amgen Inc | Anvendelse af leptin til behandling af human lipoatrofi og fremgangsmåde til bestemmelse af prædisposition for behandlinngen |
| ES2300817T3 (es) | 2003-09-08 | 2008-06-16 | Laboratoires Serono Sa | Tratamiento de enfermedades fibroticas. |
| NZ548978A (en) | 2004-02-11 | 2009-10-30 | Amylin Pharmaceuticals Inc | Hybrid polypeptides with selectable properties |
| EP1812038A1 (en) | 2004-11-18 | 2007-08-01 | VIB vzw | Fibronectin iii domain as leptin receptor antagonists |
| EP2390264A1 (en) | 2005-02-11 | 2011-11-30 | Amylin Pharmaceuticals Inc. | GIP analog and hybrid polypeptides with selectable propperties |
| US20090286723A1 (en) | 2005-02-11 | 2009-11-19 | Amylin Pharmaceuticals, Inc. | Hybrid Polypeptides with Selectable Properties |
| US7629315B2 (en) | 2005-03-09 | 2009-12-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Compositions for blocking the inhibitory effect of human CRP on human leptin |
| BRPI0614649A2 (pt) | 2005-08-11 | 2011-04-12 | Amylin Pharmaceuticals Inc | polipeptìdeos hìbridos com propriedades selecionáveis |
| ES2319048B1 (es) * | 2007-06-20 | 2010-02-10 | Universitat De Les Illes Balears | Uso de leptina en el tratamiento de alteraciones en los habitos alimentarios. |
| US8889622B2 (en) | 2007-07-25 | 2014-11-18 | Washington University | Methods of inhibiting seizure in a subject |
| GB2451858A (en) * | 2007-08-15 | 2009-02-18 | Sergiy Konovchuk | Methods of reducing body fat and treating obesity |
| KR20100093104A (ko) | 2007-12-05 | 2010-08-24 | 아스트라제네카 아베 | 항비만제로서의 피페라진 |
| CN102015668A (zh) | 2007-12-05 | 2011-04-13 | 阿斯利康(瑞典)有限公司 | 用作瘦蛋白受体调节剂的哌嗪衍生物及其用途 |
| US20110275678A1 (en) * | 2008-06-04 | 2011-11-10 | Michael Higginbottom | New Pyridine Derivatives as Leptin Receptor Modulator Mimetics |
| US20110275637A1 (en) * | 2008-06-04 | 2011-11-10 | Emma Chapman | Piperazine derivatives and their use as leptin receptor modulators |
| WO2010118384A2 (en) | 2009-04-10 | 2010-10-14 | Amylin Pharmaceuticals, Inc. | Amylin agonist compounds for estrogen-deficient mammals |
| EP2569326B1 (en) * | 2010-05-11 | 2016-08-10 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Peptide-based inhibitor of interleukin-10 or stat-3 activation |
| PT2621519T (pt) | 2010-09-28 | 2017-10-04 | Aegerion Pharmaceuticals Inc | Polipéptido de fusão de leptina-abd com duração de ação melhorada |
| CN104829707B (zh) * | 2015-05-06 | 2017-12-19 | 广东省生物资源应用研究所 | 一条cd环和e螺旋区突变的瘦素活性肽及其编码基因和应用 |
| CN110183530A (zh) * | 2019-06-21 | 2019-08-30 | 深圳市亚辉龙生物科技股份有限公司 | 瘦素免疫原、杂交瘤细胞、单克隆抗体、多克隆抗体及应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6309853B1 (en) * | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| JPH11501297A (ja) * | 1995-01-31 | 1999-02-02 | イーライ・リリー・アンド・カンパニー | 抗肥満症タンパク質 |
| WO1996023815A1 (en) * | 1995-01-31 | 1996-08-08 | Eli Lilly And Company | Ob gene product antibodies |
| US5552523A (en) * | 1995-01-31 | 1996-09-03 | Eli Lilly And Company | Anti-obesity proteins |
| WO1996031526A1 (en) * | 1995-04-06 | 1996-10-10 | Amylin Pharmaceuticals, Inc. | Anti-obesity agents |
| GB9509164D0 (en) * | 1995-05-05 | 1995-06-28 | Smithkline Beecham Plc | Novel compounds |
-
1997
- 1997-06-04 IL IL12715397A patent/IL127153A0/xx unknown
- 1997-06-04 CZ CZ983978A patent/CZ397898A3/cs unknown
- 1997-06-04 TR TR1998/02534T patent/TR199802534T2/xx unknown
- 1997-06-04 AR ARP970102432A patent/AR008765A1/es unknown
- 1997-06-04 WO PCT/EP1997/002968 patent/WO1997046585A2/en not_active Application Discontinuation
- 1997-06-04 BR BR9709529A patent/BR9709529A/pt not_active Application Discontinuation
- 1997-06-04 KR KR1019980709976A patent/KR20000016402A/ko not_active Application Discontinuation
- 1997-06-04 AU AU33372/97A patent/AU3337297A/en not_active Abandoned
- 1997-06-04 NZ NZ332879A patent/NZ332879A/xx not_active IP Right Cessation
- 1997-06-04 JP JP10500240A patent/JP2000512137A/ja active Pending
- 1997-06-04 CN CN97195311A patent/CN1221426A/zh active Pending
- 1997-06-04 CA CA002257240A patent/CA2257240A1/en not_active Abandoned
- 1997-06-04 EP EP97929156A patent/EP0912609A2/en not_active Withdrawn
- 1997-06-04 PL PL97330361A patent/PL330361A1/xx unknown
-
1998
- 1998-12-04 NO NO985683A patent/NO985683D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1221426A (zh) | 1999-06-30 |
| AU3337297A (en) | 1998-01-05 |
| EP0912609A2 (en) | 1999-05-06 |
| CZ397898A3 (cs) | 1999-04-14 |
| WO1997046585A2 (en) | 1997-12-11 |
| NZ332879A (en) | 2000-09-29 |
| JP2000512137A (ja) | 2000-09-19 |
| TR199802534T2 (xx) | 1999-03-22 |
| CA2257240A1 (en) | 1997-12-11 |
| WO1997046585A3 (en) | 1998-04-23 |
| BR9709529A (pt) | 1999-08-10 |
| KR20000016402A (ko) | 2000-03-25 |
| NO985683L (no) | 1998-12-04 |
| NO985683D0 (no) | 1998-12-04 |
| IL127153A0 (en) | 1999-09-22 |
| PL330361A1 (en) | 1999-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |