AR008168A1 - Compuestos etilamino arilamida aril substituidos de pirrolidinilo y pirrolinilo, composicion farmaceutica que lo contiene, compuesto util para susintesis, procedimiento para su preparacion - Google Patents
Compuestos etilamino arilamida aril substituidos de pirrolidinilo y pirrolinilo, composicion farmaceutica que lo contiene, compuesto util para susintesis, procedimiento para su preparacionInfo
- Publication number
- AR008168A1 AR008168A1 ARP970104054A ARP970104054A AR008168A1 AR 008168 A1 AR008168 A1 AR 008168A1 AR P970104054 A ARP970104054 A AR P970104054A AR P970104054 A ARP970104054 A AR P970104054A AR 008168 A1 AR008168 A1 AR 008168A1
- Authority
- AR
- Argentina
- Prior art keywords
- procedure
- preparation
- subsynthesis
- pirrolinyl
- pirrolidinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
Un compuesto de la fórmula (I) y las sales del mismo en la que A es halo, hidroxi o similares; la línesa de trazos representa un doble enlace opcional,con la condición de que si la línea de trazos es un doble enlace, entonces A está ausente; Ar1es fenilo opcionalmente sustituído o dimilares, Ar2 es ariloo heteroarilo seleccionado entre fenilo, naftilo, piridilo y similares, estando el arilo o el esteroarilo opcionalmente sustituído; R1 es hidrógeno, hidroxi,alquilo C1-C4 o similares; y R2y R3 se seleccionan independientemente, entre alquilo C1-C7 cicloalquilo C3-C6, alquenilo C2,C6, alquinilo C2-C6opcionalmente sustituídos y similares, o R2 y R3, junto con el átomo de nitrógeno al que están unidos, forman un anillo de pirrolidina, piperidina omorfolina opcionalmente sustituído. Los compuestos son útiles como antagonistas kappa. Se proveen tambien intermediarios para su síntesis, con porcionesfarmacéuticas que lo contienen y procedimiento para su preparación.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IBPCT/IB96/00957 | 1996-09-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR008168A1 true AR008168A1 (es) | 1999-12-09 |
Family
ID=11004480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970104054A AR008168A1 (es) | 1996-09-18 | 1997-09-04 | Compuestos etilamino arilamida aril substituidos de pirrolidinilo y pirrolinilo, composicion farmaceutica que lo contiene, compuesto util para susintesis, procedimiento para su preparacion |
Country Status (38)
Country | Link |
---|---|
US (7) | US6201007B1 (es) |
EP (1) | EP0934264B1 (es) |
JP (2) | JP3195368B2 (es) |
KR (1) | KR100339666B1 (es) |
CN (1) | CN1237962A (es) |
AP (1) | AP1016A (es) |
AR (1) | AR008168A1 (es) |
AT (1) | ATE249433T1 (es) |
AU (1) | AU719895B2 (es) |
BG (1) | BG64194B1 (es) |
BR (1) | BR9711506A (es) |
CA (1) | CA2266006C (es) |
CO (1) | CO4920224A1 (es) |
DE (1) | DE69724805T2 (es) |
DK (1) | DK0934264T3 (es) |
DZ (1) | DZ2309A1 (es) |
EA (1) | EA001341B1 (es) |
ES (1) | ES2205248T3 (es) |
HR (1) | HRP970509A2 (es) |
ID (1) | ID19611A (es) |
IL (3) | IL147368A0 (es) |
IS (1) | IS4992A (es) |
MA (1) | MA26441A1 (es) |
NO (1) | NO313550B1 (es) |
NZ (1) | NZ334439A (es) |
OA (1) | OA10996A (es) |
PA (1) | PA8437201A1 (es) |
PE (1) | PE109998A1 (es) |
PL (1) | PL332546A1 (es) |
PT (1) | PT934264E (es) |
SK (1) | SK32799A3 (es) |
TN (2) | TNSN97092A1 (es) |
TR (1) | TR199900590T2 (es) |
TW (1) | TW432047B (es) |
UA (1) | UA60310C2 (es) |
WO (1) | WO1998012177A1 (es) |
YU (1) | YU13899A (es) |
ZA (1) | ZA978358B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3053199A (en) | 1998-04-01 | 1999-10-25 | Ono Pharmaceutical Co. Ltd. | Fused thiophene derivatives and drugs containing the same as the active ingredient |
IL130429A0 (en) * | 1998-08-24 | 2000-06-01 | Pfizer Prod Inc | Process for preparing pyrrolidinyl hydroxamic acid compounds |
AU2002247886A1 (en) * | 2001-04-30 | 2002-11-11 | Pfizer Products Inc. | Process for preparing hydroxypyrrolidinyl ethylamine compounds useful as kappa agonists |
EP1478622A1 (en) * | 2002-02-28 | 2004-11-24 | Pfizer Products Inc. | Crystalline anhydrous and monohydrate benzoate salts of (2's,3s)-3-hydroxy-n- 2 n-methyl-n-4-(n-propylamino-carbonyl)phenyl]amino-2-phenyl -ethylpyrrolidine |
AU2003269399A1 (en) * | 2002-11-01 | 2004-05-25 | Pfizer Products Inc. | Process for the preparation of pyrrolidinyl ethylamine compounds via a copper-mediated aryl amination |
US7423147B2 (en) * | 2004-03-31 | 2008-09-09 | Janssen Pharmaceutical, N.V. | Pyridine compounds as histamine H3 modulators |
US7746514B2 (en) * | 2004-04-14 | 2010-06-29 | Hung-Yi Hsu | Scanner and exposure control method thereof |
US20080058312A1 (en) * | 2006-01-11 | 2008-03-06 | Angion Biomedica Corporation | Modulators of hepatocyte growth factor/c-Met activity |
WO2007143422A2 (en) * | 2006-05-30 | 2007-12-13 | Janssen Pharmaceutica N.V. | Substituted pyridyl amide compounds as modulators of the histamine h3 receptor |
JP2009542706A (ja) * | 2006-06-29 | 2009-12-03 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ヒスタミンh3受容体の置換ベンズアミドモジュレーター |
NZ584998A (en) | 2007-11-20 | 2012-08-31 | Janssen Pharmaceutica Nv | Cycloalkyloxy-and heterocycloalkyloxypyridine compounds as modulators of the histamine h3 receptor |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8801304D0 (en) * | 1988-01-21 | 1988-02-17 | Ici Plc | Diamine compounds |
US5232978A (en) * | 1988-12-23 | 1993-08-03 | Merck Patent Gesellschaft Mit Beschrankter Haftung | 1-(2-arylethyl)-pyrrolidines |
DE3935371A1 (de) | 1988-12-23 | 1990-07-05 | Merck Patent Gmbh | Stickstoffhaltige ringverbindungen |
DE4034785A1 (de) * | 1990-11-02 | 1992-05-07 | Merck Patent Gmbh | 1-(2-arylethyl)-pyrrolidine |
WO1994018165A1 (en) | 1993-02-12 | 1994-08-18 | Pfizer Inc. | Sulfonamide compounds as opioid k-receptor agonists |
IL117440A0 (en) * | 1995-03-31 | 1996-07-23 | Pfizer | Pyrrolidinyl hydroxamic acid compounds and their production process |
-
1997
- 1997-05-27 TN TNTNSN97092A patent/TNSN97092A1/fr unknown
- 1997-08-20 TW TW086111948A patent/TW432047B/zh active
- 1997-08-21 SK SK327-99A patent/SK32799A3/sk unknown
- 1997-08-21 EA EA199900209A patent/EA001341B1/ru not_active IP Right Cessation
- 1997-08-21 CA CA002266006A patent/CA2266006C/en not_active Expired - Fee Related
- 1997-08-21 DK DK97934676T patent/DK0934264T3/da active
- 1997-08-21 IL IL14736897A patent/IL147368A0/xx unknown
- 1997-08-21 BR BR9711506A patent/BR9711506A/pt not_active Application Discontinuation
- 1997-08-21 TR TR1999/00590T patent/TR199900590T2/xx unknown
- 1997-08-21 CN CN97199817A patent/CN1237962A/zh active Pending
- 1997-08-21 US US09/254,805 patent/US6201007B1/en not_active Expired - Fee Related
- 1997-08-21 AU AU37812/97A patent/AU719895B2/en not_active Ceased
- 1997-08-21 DE DE69724805T patent/DE69724805T2/de not_active Expired - Fee Related
- 1997-08-21 PT PT97934676T patent/PT934264E/pt unknown
- 1997-08-21 WO PCT/IB1997/001021 patent/WO1998012177A1/en not_active Application Discontinuation
- 1997-08-21 IL IL12895997A patent/IL128959A0/xx unknown
- 1997-08-21 NZ NZ334439A patent/NZ334439A/xx unknown
- 1997-08-21 YU YU13899A patent/YU13899A/sh unknown
- 1997-08-21 ES ES97934676T patent/ES2205248T3/es not_active Expired - Lifetime
- 1997-08-21 EP EP97934676A patent/EP0934264B1/en not_active Expired - Lifetime
- 1997-08-21 UA UA99031459A patent/UA60310C2/uk unknown
- 1997-08-21 JP JP51443398A patent/JP3195368B2/ja not_active Expired - Fee Related
- 1997-08-21 KR KR1019997002287A patent/KR100339666B1/ko not_active IP Right Cessation
- 1997-08-21 IL IL14736797A patent/IL147367A0/xx unknown
- 1997-08-21 PL PL97332546A patent/PL332546A1/xx unknown
- 1997-08-21 AT AT97934676T patent/ATE249433T1/de not_active IP Right Cessation
- 1997-08-29 PA PA19978437201A patent/PA8437201A1/es unknown
- 1997-09-04 AR ARP970104054A patent/AR008168A1/es not_active Application Discontinuation
- 1997-09-11 AP APAP/P/1997/001082A patent/AP1016A/en active
- 1997-09-15 MA MA24796A patent/MA26441A1/fr unknown
- 1997-09-16 TN TNTNSN97156A patent/TNSN97156A1/fr unknown
- 1997-09-16 ID IDP973203A patent/ID19611A/id unknown
- 1997-09-17 DZ DZ970159A patent/DZ2309A1/xx active
- 1997-09-17 ZA ZA978358A patent/ZA978358B/xx unknown
- 1997-09-17 CO CO97054286A patent/CO4920224A1/es unknown
- 1997-09-18 PE PE1997000834A patent/PE109998A1/es not_active Application Discontinuation
- 1997-09-18 HR HRPCT/IB96/00957A patent/HRP970509A2/hr not_active Application Discontinuation
-
1999
- 1999-03-05 IS IS4992A patent/IS4992A/is unknown
- 1999-03-11 BG BG103239A patent/BG64194B1/bg unknown
- 1999-03-12 OA OA9900057A patent/OA10996A/en unknown
- 1999-03-17 NO NO19991294A patent/NO313550B1/no unknown
-
2001
- 2001-01-26 US US09/770,515 patent/US6310061B2/en not_active Expired - Fee Related
- 2001-01-26 US US09/771,029 patent/US6307061B2/en not_active Expired - Fee Related
- 2001-01-26 US US09/771,030 patent/US6294557B1/en not_active Expired - Fee Related
- 2001-01-26 US US09/770,512 patent/US6303602B1/en not_active Expired - Fee Related
- 2001-01-26 US US09/770,513 patent/US6313302B2/en not_active Expired - Fee Related
- 2001-01-26 US US09/770,514 patent/US6294569B2/en not_active Expired - Fee Related
- 2001-03-28 JP JP2001092342A patent/JP2001316344A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA199800404A1 (ru) | Производные 1-(1,2-дизамещенный пиперидинил)-4-замещенного пиперазина | |
AR027263A1 (es) | Derivados de 1,3-dihidro-2h-indol-2-ona, un procedimiento para su preparacion y las composiciones farmaceuticas que los contienen. | |
ES2190396T3 (es) | Nuevos compuestos amino-triazoles, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
PE20021056A1 (es) | Derivados de pirazol | |
ES2053508T3 (es) | Compuestos de acidos 3-pirrolidinil-tio-1-azabiciclo(3.2.0)hept-2-eno-2-carboxilicos. | |
AR009413A1 (es) | Un compuesto, el cual es un derivado de distamicina benzoheterociclico, su utilizacion, un procedimiento para producirlo y una composicionfarmaceutica que lo comprende | |
CO5580815A2 (es) | Derivados de adamantana, procesos para su preparacion y composiciones farmaceuticas que los contienen | |
AR245447A1 (es) | Procedimiento para preparar derivados de 2,4-diamino-5-(biciclo-sustituido)metilpirimidinas. | |
AR008168A1 (es) | Compuestos etilamino arilamida aril substituidos de pirrolidinilo y pirrolinilo, composicion farmaceutica que lo contiene, compuesto util para susintesis, procedimiento para su preparacion | |
ES2195933T3 (es) | Nuevos derivados de flavonas, xantonas y cumarinas. | |
AR027539A1 (es) | Nuevos derivados de 1,3-dihidro-2h-indol-2-ona, un procedimiento para su preparacion y las composiciones farmaceuticas que los contienen | |
NO20025640D0 (no) | Substituerte 1-aminoalkyl-laktamer og deres anvendelse som muscarin-reseptor-antagonister | |
AR039988A1 (es) | Derivados de benzoxazina como moduladores de 5-ht6 y usos de los mismos | |
ES2106936T5 (es) | Derivados de carbazolona y procedimientos para su preparacion. | |
CO5590934A2 (es) | Procedimiento de preparacion de derivados de equinocandina | |
AR041720A1 (es) | Derivados de n- benzodioxolilo, n- benzodioxanilo y n- benzodioxepinilarilcarboxamida que pueden usarse para el tratamiento de dislipidemia, y composiciones farmaceuticas que los contienen | |
ES2172294T3 (es) | Nuevos derivados del 1-indanol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
ES2057415T3 (es) | Derivados biciclicos. | |
AR029937A1 (es) | Utilizacion de derivados de 2-aminotiazolina para la preparacion de medicamentos, derivados de 2-aminotiazolina y sus procedimientos de preparacion, las composiciones farmaceuticas que contienen dichos derivados, los compuestos intermediarios en la preparacion de dichos derivados y los procedimiento | |
ES2189736T3 (es) | Derivados de la benzamida y medicamentos que los contienen. | |
NO904135L (no) | Fremgangsmaate for fremstilling av nye substituerte alkylpiperidiner og deres anvendelse som inhibitorer av kolesterolsyntese. | |
CO4980875A1 (es) | Nuevos derivados de la equinocandina, su procedimiento de preparacion y su aplicacion como fungicidas | |
ECSP972260A (es) | Compuestos de pirrolinil etilamina como agonistas kappa | |
AR023528A1 (es) | Derivados de ciclobuten-3,4-diona, su preparacion y su aplicacion en terapeutica | |
GB1028234A (en) | New pharmaceutical compositions comprising 5-aminodibenzocycloheptene derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |