ZA989783B - Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents - Google Patents

Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents

Info

Publication number
ZA989783B
ZA989783B ZA989783A ZA989783A ZA989783B ZA 989783 B ZA989783 B ZA 989783B ZA 989783 A ZA989783 A ZA 989783A ZA 989783 A ZA989783 A ZA 989783A ZA 989783 B ZA989783 B ZA 989783B
Authority
ZA
South Africa
Prior art keywords
antibacterial agents
novel
substituted quinazolin
diones useful
diones
Prior art date
Application number
ZA989783A
Other languages
English (en)
Inventor
John Michael Domagala
Edmund Lee Ellsworth
Liren Huang
Thomas Eric Renau
Rajeshwar Singh
Michael Andrew Stier
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA989783B publication Critical patent/ZA989783B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
ZA989783A 1997-10-28 1998-10-27 Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents ZA989783B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6355697P 1997-10-28 1997-10-28
US9858898P 1998-08-31 1998-08-31

Publications (1)

Publication Number Publication Date
ZA989783B true ZA989783B (en) 1999-04-28

Family

ID=26743531

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA989783A ZA989783B (en) 1997-10-28 1998-10-27 Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents

Country Status (11)

Country Link
US (2) US6331538B1 (xx)
EP (1) EP1028950B1 (xx)
AT (1) ATE239000T1 (xx)
AU (1) AU9503998A (xx)
DE (1) DE69814135T2 (xx)
DK (1) DK1028950T3 (xx)
ES (1) ES2195397T3 (xx)
PT (1) PT1028950E (xx)
SI (1) SI1028950T1 (xx)
WO (1) WO1999021840A1 (xx)
ZA (1) ZA989783B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2483400A (en) * 1999-01-13 2000-08-01 Warner-Lambert Company 4'heteroaryl diarylamines
EA005585B1 (ru) 2000-01-24 2005-04-28 Уорнер-Ламберт Компани 3-аминохиназолин-2,4-дионовые антибактериальные агенты
US7105682B2 (en) * 2001-01-12 2006-09-12 Amgen Inc. Substituted amine derivatives and methods of use
EP1395585B1 (en) 2001-05-30 2006-01-04 Warner-Lambert Company LLC Antibacterial agents
JP2005501021A (ja) * 2001-06-19 2005-01-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗細菌剤
EP1467968A1 (en) 2002-01-23 2004-10-20 Warner-Lambert Company LLC N-(4-substituted phenyl)-anthranilic acid hydroxamate esters
DOP2003000556A (es) 2002-01-23 2003-10-31 Warner Lambert Co Esteres hidroxamato de acido n-(4-fenil-sustituido)-antranilico.
BRPI0414319A (pt) * 2003-09-12 2006-11-07 Warner Lambert Co agentes antibacterianos de quinolona
US20050124562A1 (en) * 2003-09-23 2005-06-09 Joseph Guiles Bis-quinazoline compounds for the treatment of bacterial infections
JP4533391B2 (ja) 2004-01-16 2010-09-01 エフ.ホフマン−ラ ロシュ アーゲー 中枢神経系疾患の処置のための5−ヒドロキシトリプタミンレセプター(5−ht)のモジュレーターとしての、1−ベンジル−5−ピペラジン−1−イル−3,4−ジヒドロ−1h−キナゾリン−2−オン誘導体、ならびにそれぞれの1h−ベンゾ(1,2,6)チアジアジン−2,2−ジオキシドおよび1,4−ジヒドロベンゾ(d)(1,3)オキサジン−2−オン誘導体
WO2006019965A2 (en) * 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
US7767687B2 (en) * 2004-12-13 2010-08-03 Biogen Idec Ma Inc. Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as RAF kinase inhibitors
US7973022B2 (en) * 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
WO2008061866A1 (en) * 2006-11-20 2008-05-29 Bayer Cropscience Sa New benzamide derivatives
JP2012527461A (ja) * 2009-05-19 2012-11-08 ダウ アグロサイエンシィズ エルエルシー 真菌を防除するための化合物および方法
WO2010144647A1 (en) 2009-06-12 2010-12-16 Bristol-Myers Squibb Company Nicotinamide compounds useful as kinase modulators
WO2011031745A1 (en) * 2009-09-09 2011-03-17 Achaogen, Inc. Antibacterial fluoroquinolone analogs
WO2013076590A1 (en) * 2011-11-23 2013-05-30 Oxygen Healthcare Research Pvt. Ltd Benzothiazine compounds as h3 receptor ligands
AU2016325601C1 (en) * 2015-09-25 2022-03-31 Ludwig Institute For Cancer Research Ltd. 3-hydroxy-quinazoline-2,4-dione derivatives and their use as nuclease modulators
TW202208355A (zh) 2020-05-04 2022-03-01 美商安進公司 作為骨髓細胞觸發受體2促效劑之雜環化合物及使用方法
BR112022022338A2 (pt) 2020-05-04 2023-01-10 Amgen Inc Compostos heterocíclicos como receptor desencadeador expresso em agonistas de células mieloides 2 e métodos de uso

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1068263B (xx) 1959-11-05
US5155110A (en) * 1987-10-27 1992-10-13 Warner-Lambert Company Fenamic acid hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition
US5283248A (en) 1989-11-21 1994-02-01 Hoffmann-La Roche Inc. Amino substituted pyrimido[1,6-2]benzimidazoles
JP3002507B2 (ja) 1990-08-03 2000-01-24 大日本製薬株式会社 四環式化合物

Also Published As

Publication number Publication date
DK1028950T3 (da) 2003-09-01
WO1999021840A1 (en) 1999-05-06
EP1028950B1 (en) 2003-05-02
AU9503998A (en) 1999-05-17
ES2195397T3 (es) 2003-12-01
US20020115674A1 (en) 2002-08-22
ATE239000T1 (de) 2003-05-15
EP1028950A1 (en) 2000-08-23
US6825199B2 (en) 2004-11-30
PT1028950E (pt) 2003-09-30
US6331538B1 (en) 2001-12-18
SI1028950T1 (en) 2003-08-31
DE69814135D1 (de) 2003-06-05
DE69814135T2 (de) 2004-04-01

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