ZA988421B - A novel composition for controlled and sustained transdermal administration - Google Patents

A novel composition for controlled and sustained transdermal administration

Info

Publication number
ZA988421B
ZA988421B ZA988421A ZA988421A ZA988421B ZA 988421 B ZA988421 B ZA 988421B ZA 988421 A ZA988421 A ZA 988421A ZA 988421 A ZA988421 A ZA 988421A ZA 988421 B ZA988421 B ZA 988421B
Authority
ZA
South Africa
Prior art keywords
controlled
transdermal administration
novel composition
sustained transdermal
sustained
Prior art date
Application number
ZA988421A
Other languages
English (en)
Inventor
Dario Carrara
Original Assignee
Permatec Tech Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Permatec Tech Ag filed Critical Permatec Tech Ag
Publication of ZA988421B publication Critical patent/ZA988421B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA988421A 1997-09-17 1998-09-15 A novel composition for controlled and sustained transdermal administration ZA988421B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI002106A IT1294748B1 (it) 1997-09-17 1997-09-17 Formulazione per un dispositivo transdermico

Publications (1)

Publication Number Publication Date
ZA988421B true ZA988421B (en) 1999-03-17

Family

ID=11377881

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA988421A ZA988421B (en) 1997-09-17 1998-09-15 A novel composition for controlled and sustained transdermal administration

Country Status (14)

Country Link
US (1) US6231885B1 (ko)
EP (1) EP0913158B1 (ko)
JP (1) JPH11152224A (ko)
KR (1) KR19990029891A (ko)
AR (1) AR019001A1 (ko)
AT (1) ATE238777T1 (ko)
AU (1) AU742399B2 (ko)
CA (1) CA2247767A1 (ko)
DE (1) DE69813988D1 (ko)
IL (1) IL126267A0 (ko)
IT (1) IT1294748B1 (ko)
NZ (1) NZ331904A (ko)
TW (1) TW493994B (ko)
ZA (1) ZA988421B (ko)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
DE19828274C2 (de) * 1998-06-25 2002-11-28 Rottapharm Bv Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren
US20020160995A1 (en) * 1998-08-03 2002-10-31 Easterling W. Jerry Medication and method for remediating existing scars through transdermal, topical delivery of calcium channel blockers
AU5325000A (en) * 1999-06-05 2000-12-28 David Houze Solubility enhancement of drugs in transdermal drug delivery systems and methodsof use
DE19950066A1 (de) * 1999-10-16 2001-04-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit einem Gehalt an Tulobuterol-hydrochlorid zur Verabreichung des Bronchodilatators Tulobuterol über die Haut
AU3104301A (en) 2000-01-20 2001-07-31 Noven Pharmaceuticals, Inc. Compositions and methods to effect the release profile in the transdermal administration of active agents
DE10015783C2 (de) * 2000-03-30 2003-12-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Abgabe von Lerisetron und seine Verwendung
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
AUPR549901A0 (en) * 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
KR20020037616A (ko) * 2000-11-15 2002-05-22 서경배 케토롤락의 경피흡수제제
TWI287455B (en) * 2000-12-05 2007-10-01 Noven Pharma Crystallization inhibition of drugs in transdermal drug delivery systems and methods of use
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
US20040170672A1 (en) * 2001-03-07 2004-09-02 Thorsten Selzer Transdermal therapeutic system for administration of partial dopamine-d2 agonists
US7988991B2 (en) * 2001-03-07 2011-08-02 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch
RU2708563C2 (ru) * 2001-03-16 2019-12-10 Алза Корпорейшн Трансдермальный пластырь для введения фентанила
US20050208117A1 (en) * 2001-03-16 2005-09-22 Venkatraman Subramanian S Transdermal administration of fentanyl and analogs thereof
DE10114382A1 (de) * 2001-03-23 2002-09-26 Beiersdorf Ag Feuchtigkeitsaufnehmende Matrix auf Silikonbasis insbesondere zur Wundversorgung und/oder pharmazeutisch/kosmetischen Hautbehandlung
ATE438418T1 (de) * 2001-05-01 2009-08-15 Av Topchiev Inst Petrochemical Hydrogel-zusammensetzungen
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
DE60239528D1 (de) * 2001-05-01 2011-05-05 Corium International Redwood City Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US20050215727A1 (en) * 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US20030018074A1 (en) * 2001-07-06 2003-01-23 Robert Kleiman Antiviral composition and treatment method
US20040241240A1 (en) * 2001-08-10 2004-12-02 Takaaki Terahara Percutaneous absorption preparations
US7247315B2 (en) * 2001-08-17 2007-07-24 Lavipharm Laboratories Inc. Compositions and medical device for transdermal delivery of a drug and methods of making and using same
DE10159120B4 (de) * 2001-12-01 2006-08-17 Lts Lohmann Therapie-Systeme Ag Steroidhormonhaltige transdermale therapeutische Systeme enthaltend Propylenglycolmonocaprylat und seine Verwendung
US7921999B1 (en) 2001-12-20 2011-04-12 Watson Laboratories, Inc. Peelable pouch for transdermal patch and method for packaging
US20060088579A1 (en) * 2002-02-07 2006-04-27 Shastri Venkatram P Transdermal drug delivery systems
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ES2307955T3 (es) * 2002-03-06 2008-12-01 Hexal Ag Sistema transdermico con fentanil.
KR20050050615A (ko) 2002-04-23 2005-05-31 알자 코포레이션 남용될 가능성이 감소된 경피용 진통제 시스템
KR20050045946A (ko) 2002-06-25 2005-05-17 애크럭스 디디에스 피티와이 리미티드 비정질 약학적 조성물을 이용한 경피전달속도의 제어
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
JP4354678B2 (ja) * 2002-08-28 2009-10-28 久光製薬株式会社 貼付剤
US20040086551A1 (en) 2002-10-30 2004-05-06 Miller Kenneth J. Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl
CA2729967C (en) * 2002-12-13 2018-01-16 Schering-Plough Healthcare Products, Inc. Use of a transdermal or transmucosal ingredient delivery device
DE10304988A1 (de) * 2003-02-07 2004-09-09 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit verbessertem Hautklebeverhalten
ME00524B (me) 2003-03-10 2011-10-10 Astrazeneca Ab Novi postupak za dobijanje roflumilasta
US8790689B2 (en) 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
MY141815A (en) * 2003-04-30 2010-06-30 Purdue Pharma Lp Tamper-resistant transdermal dosage form comprising an active agent component and an adverse agent component at the distal site of the active agent layer
CA2530996C (en) * 2003-07-03 2013-05-07 Corium International, Inc. Wound dressing, ingredient delivery device and iv hold-down, and method relating to same
EP1652508B1 (en) * 2003-07-31 2013-12-04 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch
US20070053966A1 (en) * 2003-10-17 2007-03-08 Robert Ang Medicated orthopedic support structures for treatment of damaged musculoskeletal tissue
US20070059351A1 (en) * 2003-10-17 2007-03-15 Murrell George A C Transdermal patches containing a nitric oxide-donor and a second active agent and associated methods
US20060286158A1 (en) * 2003-10-17 2006-12-21 Calvert Murrell George A Treatment of overuse tendinopathy using transdermal nitric oxide-generating agents
US20060286159A1 (en) * 2003-10-17 2006-12-21 Calvert Murrell George A Treatment of persistent active tendinopathy using transdermal glyceryl trinitrate providing durability of effect
CN1929819B (zh) 2004-01-30 2012-02-29 考里安国际公司 递送活性剂的快速溶解膜
CA2557354C (en) * 2004-03-03 2013-05-07 Vital Health Sciences Pty Ltd. Alkaloid formulations
CA2575587C (en) * 2004-08-03 2014-06-17 Vital Health Sciences Pty Ltd Carrier for enteral administration
CA2576158C (en) * 2004-08-05 2020-10-27 Corium International, Inc. Adhesive composition
ES2265239B1 (es) * 2004-09-23 2008-02-01 Laboratorio Reig Jofre, S.A. Composicion farmaceutica para administracion transdermica.
CA2583642C (en) 2004-10-21 2013-06-25 Durect Corporation Transdermal delivery systems
US8252320B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
US20060188558A1 (en) * 2005-02-18 2006-08-24 Mylan Technologies, Inc. Transdermal systems having control delivery system
US20090239827A1 (en) * 2005-03-03 2009-09-24 Esra Ogru Compounds having lipid lowering properties
WO2006097456A1 (en) * 2005-03-16 2006-09-21 Nycomed Gmbh Taste masked dosage form containing roflumilast
ITMI20050477A1 (it) * 2005-03-23 2006-09-24 Bouty S P A Cerotto transdermico
US9168216B2 (en) 2005-06-17 2015-10-27 Vital Health Sciences Pty. Ltd. Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US20110086086A1 (en) * 2005-07-26 2011-04-14 Pfizer Inc Transdermal system for varenicline
US7884158B2 (en) * 2005-09-06 2011-02-08 L'Oré´al Cosmetic compositions containing block copolymers, tackifiers and phenylated silicones
US20070104771A1 (en) * 2005-09-23 2007-05-10 Jay Audett Transdermal galantamine delivery system
US8383149B2 (en) 2005-09-23 2013-02-26 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
US9056061B2 (en) * 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
DE102005056393A1 (de) * 2005-11-24 2007-05-31 Grünenthal GmbH Multicyclische Verbindungen in druckempfindlichen Klebstoffen
US20070122699A1 (en) * 2005-11-30 2007-05-31 Rovcal, Inc. Electrochemical cells having improved gelling agents
US20070202155A1 (en) * 2006-02-03 2007-08-30 Cure Therapeutics, Inc. Low dose no donor-containing transdermal patch
US20070259026A1 (en) * 2006-04-20 2007-11-08 Robert Ang Vasodialating dressing for use with intravenous catheters
US20080152592A1 (en) * 2006-12-21 2008-06-26 Bayer Healthcare Llc Method of therapeutic drug monitoring
WO2008115224A2 (en) * 2007-03-20 2008-09-25 Bayer Healthcare Llc Method of analyzing an analyte
DE102007041557B4 (de) * 2007-08-29 2011-03-31 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend längliche Hohlkörper
US8470360B2 (en) 2008-04-18 2013-06-25 Warsaw Orthopedic, Inc. Drug depots having different release profiles for reducing, preventing or treating pain and inflammation
RU2499583C2 (ru) * 2007-10-15 2013-11-27 Алза Корпорейшн Заместительное трансдермальное введение фентанила один раз в день
DE102007060175A1 (de) * 2007-12-13 2009-06-18 Johannes Gutenberg-Universität Mainz Quartärnisierung des Zusatzstoffs Aminoalkyl Methacrylat Copolymer E zur Verbesserung der Permeabilität und Löslichkeit von Arzneistoffen
WO2009106831A2 (en) 2008-02-28 2009-09-03 Syntropharma Limited Pharmaceutical composition
US20090263456A1 (en) * 2008-04-18 2009-10-22 Warsaw Orthopedic, Inc. Methods and Compositions for Reducing Preventing and Treating Adhesives
WO2010083035A2 (en) * 2009-01-14 2010-07-22 Corium International, Inc. Transdermal administration of tamsulosin
WO2011068722A1 (en) * 2009-12-01 2011-06-09 Noven Pharmaceuticals, Inc. Transdermal testosterone device and delivery
AU2011213557B2 (en) 2010-02-05 2015-05-07 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
BR112012024835A2 (pt) 2010-03-30 2016-06-07 Phosphagenics Ltd adesivo de distribuição transdérmica
AU2011248904B2 (en) * 2010-04-30 2014-02-27 Teikoku Seiyaku Co., Ltd. Propynylaminoindan transdermal compositions
WO2012122586A1 (en) 2011-03-15 2012-09-20 Phosphagenics Limited New composition
JP5906302B2 (ja) 2011-03-24 2016-04-20 テイコク ファーマ ユーエスエー インコーポレーテッド 作用剤層および作用剤変換層を含む経皮組成物
CN102895358A (zh) * 2011-07-29 2013-01-30 苏州知微堂生物科技有限公司 一种三黄汤整合型新剂型制备技术及其生产方法
WO2013067346A1 (en) * 2011-11-04 2013-05-10 Agile Therapeutics, Inc. Dermal delivery compositions and methods
US9913812B2 (en) 2011-11-09 2018-03-13 Teikoku Pharma Usa, Inc. Methods for the treatment of skin neoplasms
KR101856515B1 (ko) 2012-11-02 2018-05-10 테이코쿠 팔마 유에스에이, 인코포레이티드 프로피닐아미노인단 경피 조성물
EP3150205B1 (en) * 2014-05-28 2021-02-17 Teikoku Seiyaku Co., Ltd. Transdermal preparation
ES2784756T3 (es) 2014-07-18 2020-09-30 Buzzz Pharmaceuticals Ltd Parche transdérmico opioide/antagonista de opioides disuasivo del abuso
US9789070B2 (en) 2015-07-28 2017-10-17 Elc Management Llc Sheet packs for treating facial or body surfaces
EP3383371B1 (en) 2015-12-09 2024-05-01 Avecho Biotechnology Limited Pharmaceutical formulation
JP6556873B2 (ja) * 2016-01-28 2019-08-07 久光製薬株式会社 経皮吸収製剤
WO2018006069A1 (en) * 2016-06-30 2018-01-04 Teva Pharmaceuticals International Gmbh Improved formulations for transdermal pharmaceutical systems
CA3045702A1 (en) 2016-12-21 2018-06-28 Phosphagenics Limited Phosphorylation process of complex alcohols
US10406114B2 (en) * 2017-06-11 2019-09-10 Masoumeh Nasrollahzadeh Abyazani Antibiotic-loaded transdermal patch

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4764381A (en) 1985-12-06 1988-08-16 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol
US4863970A (en) 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US5023084A (en) 1986-12-29 1991-06-11 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US4816258A (en) 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
US4788062A (en) 1987-02-26 1988-11-29 Alza Corporation Transdermal administration of progesterone, estradiol esters, and mixtures thereof
HU210549B (en) 1988-10-27 1995-05-29 Schering Ag Process for producing transdermally applicable pharmaceutical composition containing gestodene
IL92537A (en) * 1988-12-15 1994-04-12 Riker Laboratories Inc Topical preparations and dermal systems containing 1-isobutyl-H1-imidazo [C-4,5] quinoline-4-amine
US4973468A (en) 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
US5091186A (en) 1989-08-15 1992-02-25 Cygnus Therapeutic Systems Biphasic transdermal drug delivery device
SE8904296D0 (sv) 1989-12-21 1989-12-21 Pharmacia Ab Transdermal system
GB9021674D0 (en) 1990-10-05 1990-11-21 Ethical Pharma Ltd Transdermal device
US5225198A (en) 1991-08-27 1993-07-06 Cygnus Therapeutic Systems Transdermal administration of short or intermediate half-life benzodiazepines
US5229130A (en) 1991-12-20 1993-07-20 Cygnus Therapeutics Systems Vegetable oil-based skin permeation enhancer compositions, and associated methods and systems
AU677206B2 (en) 1992-06-11 1997-04-17 Theratech, Inc. The use of glycerin in moderating transdermal drug delivery
CA2166780A1 (en) 1993-07-08 1995-01-19 Ooi Wong Monolithic matrix transdermal delivery system
US5466465A (en) 1993-12-30 1995-11-14 Harrogate Holdings, Limited Transdermal drug delivery system
WO1995029678A1 (en) * 1994-04-28 1995-11-09 F.Hoffmann-La Roche Ag Pharmaceutical composition for transdermal delivery

Also Published As

Publication number Publication date
NZ331904A (en) 1999-03-29
JPH11152224A (ja) 1999-06-08
TW493994B (en) 2002-07-11
EP0913158B1 (en) 2003-05-02
AU8423098A (en) 1999-04-01
DE69813988D1 (de) 2003-06-05
AU742399B2 (en) 2002-01-03
ATE238777T1 (de) 2003-05-15
KR19990029891A (ko) 1999-04-26
IL126267A0 (en) 1999-05-09
EP0913158A1 (en) 1999-05-06
AR019001A1 (es) 2001-12-26
ITMI972106A1 (it) 1999-03-17
IT1294748B1 (it) 1999-04-12
CA2247767A1 (en) 1999-03-17
US6231885B1 (en) 2001-05-15

Similar Documents

Publication Publication Date Title
IL126267A0 (en) A novel composition for controlled and sustained transdermal administration
AU1302499A (en) Buffered drug formulations for transdermal electrotransport delivery
HUP0002209A3 (en) 4-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives and pharmaceutical compositions containing them
HUP9802983A3 (en) Composition for transdermal delivery
PL337348A1 (en) Pharmaceutic composition comprising a combination of piperidinylalkanol and a decongestant
GB9706089D0 (en) Pharmaceutical composition
EP0941039A4 (en) TRANSDERMAL ADMINISTRATION OF 7alpha-METHYL-19-NORTESTOSTERONE ("MENT")
AU8695698A (en) Pharmacologic drug combination in vagal-induced asystole
IL125820A0 (en) Therapeutic agent for diabetes and a pharmaceutical composition containing the same
EP0978288A4 (en) DRUG COMPOSITION
HUP9800832A3 (en) Transdermal formulation
HUP9802070A3 (en) Transdermal formulation
AU2345695A (en) Pharmaceutical composition for transdermal delivery
GB9717444D0 (en) Pharmaceutical composition
HUP0002455A3 (en) Gastric-retained pharmaceutical composition
IL116999A0 (en) Transdermal formulation
GB9717428D0 (en) Pharmaceutical composition
IL122920A (en) Castrointestinal drug composition
PL322596A1 (en) Antiglucocorticoid drug
AU732214C (en) Biphenyl derivatives and drug composition
GB9705989D0 (en) Therapeutic composition
AU1143899A (en) Transdermal delivery of 3,4-diarylchromans
HUP0004132A3 (en) Rapidly soluble drug composition
GB2321190B (en) Pharmaceutical composition
HU9701121D0 (en) New transdermal drug formulation