ZA983602B - Use of tetrahydropyridine derivatives for the preparation of drugs for the treatment of diseases which cause demyelination - Google Patents

Use of tetrahydropyridine derivatives for the preparation of drugs for the treatment of diseases which cause demyelination

Info

Publication number
ZA983602B
ZA983602B ZA983602A ZA983602A ZA983602B ZA 983602 B ZA983602 B ZA 983602B ZA 983602 A ZA983602 A ZA 983602A ZA 983602 A ZA983602 A ZA 983602A ZA 983602 B ZA983602 B ZA 983602B
Authority
ZA
South Africa
Prior art keywords
drugs
diseases
preparation
treatment
tetrahydropyridine derivatives
Prior art date
Application number
ZA983602A
Other languages
English (en)
Inventor
Bernard Bourrie
Pierre Casellas
Jean-Pierre Maffrand
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA983602B publication Critical patent/ZA983602B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
ZA983602A 1997-04-29 1998-04-29 Use of tetrahydropyridine derivatives for the preparation of drugs for the treatment of diseases which cause demyelination ZA983602B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9705275A FR2762514B1 (fr) 1997-04-29 1997-04-29 Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation

Publications (1)

Publication Number Publication Date
ZA983602B true ZA983602B (en) 1998-11-02

Family

ID=9506415

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA983602A ZA983602B (en) 1997-04-29 1998-04-29 Use of tetrahydropyridine derivatives for the preparation of drugs for the treatment of diseases which cause demyelination

Country Status (18)

Country Link
US (1) US6344464B1 (es)
EP (1) EP0979079B1 (es)
JP (1) JP3956059B2 (es)
AR (1) AR012504A1 (es)
AT (1) ATE269077T1 (es)
AU (1) AU7436498A (es)
BR (1) BR9810234A (es)
CA (1) CA2288241C (es)
DE (1) DE69824576T2 (es)
DK (1) DK0979079T3 (es)
ES (1) ES2222593T3 (es)
FR (1) FR2762514B1 (es)
NO (1) NO325163B1 (es)
PT (1) PT979079E (es)
SI (1) SI0979079T1 (es)
UY (1) UY24973A1 (es)
WO (1) WO1998048802A1 (es)
ZA (1) ZA983602B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
WO2002085888A1 (fr) * 2001-04-20 2002-10-31 Sanofi-Synthelabo Tetrahydropyridyl-alkyl-heterocycles, procede pour leur preparation et compositions pharmaceutiques les contenants
FR2823748B1 (fr) * 2001-04-20 2004-02-20 Sanofi Synthelabo Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant
WO2003002187A2 (en) * 2001-06-26 2003-01-09 Photomed Technologies, Inc. Multiple wavelength illuminator
CA2451955C (en) 2001-06-26 2015-09-29 Abgenix, Inc. Antibodies to opgl
FR2831166B1 (fr) * 2001-10-18 2004-02-27 Sanofi Synthelabo Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant
DK2213685T3 (en) 2002-09-06 2014-03-03 Medarex Llc Therapeutic anti-IL-1R1 monoclonal antibody
JP2006517191A (ja) * 2002-12-30 2006-07-20 アムジエン・インコーポレーテツド 共刺激因子を用いた併用療法
US7838522B2 (en) 2004-11-17 2010-11-23 Ares Trading S.A. Benzothiazole formulations and use thereof
JP5021488B2 (ja) 2004-12-21 2012-09-05 メルク セローノ ソシエテ アノニム スルホニルアミノ環式誘導体及びその使用
DK1844032T3 (da) 2005-01-31 2011-10-24 Merck Serono Sa N-hydroxyamid-derivater og deres anvendelse
BRPI0613042A2 (pt) 2005-07-15 2010-12-14 Serono Lab inibidores de jnk para o tratamento de endometriose
KR20080036084A (ko) * 2005-07-15 2008-04-24 라보라뚜와르 세로노 에스. 에이. 자가면역 및/또는 염증성 질환 치료용 Glepp―1억제제
KR20080044836A (ko) 2005-07-15 2008-05-21 라보라뚜와르 세로노 에스. 에이. 자궁내막증 치료용 jnk 억제제
CA2616479A1 (en) 2005-09-01 2007-03-08 Ares Trading S.A. Treatment of optic neuritis
EP2628727A3 (en) * 2007-11-21 2013-12-25 Decode Genetics EHF Biaryl PDE4 inhibitors for treating pulmonary and cardiovascular disorders
KR101707597B1 (ko) * 2010-12-07 2017-02-17 한국전자통신연구원 홀 센서리스 bldc 모터용 전원 공급 모듈
WO2020035482A1 (en) 2018-08-13 2020-02-20 Iltoo Pharma Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof
WO2023118544A1 (en) 2021-12-23 2023-06-29 Cilcare Dev 4-phenyl-tetrahydropyridine derivatives for treating hearing diseases
WO2023222565A1 (en) 2022-05-16 2023-11-23 Institut National de la Santé et de la Recherche Médicale Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531707A1 (fr) 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
FR2662355B1 (fr) 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines
FR2740343B1 (fr) * 1995-10-26 1999-01-22 Sanofi Sa Utilisation de la 1-(2-napht-2-yl-ethyl)-4- (3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de la sclerose laterale amyotrophique

Also Published As

Publication number Publication date
PT979079E (pt) 2004-10-29
CA2288241C (en) 2006-10-03
SI0979079T1 (en) 2004-10-31
UY24973A1 (es) 1998-07-16
FR2762514B1 (fr) 1999-10-22
NO995245D0 (no) 1999-10-27
DK0979079T3 (da) 2004-10-25
EP0979079B1 (fr) 2004-06-16
WO1998048802A1 (fr) 1998-11-05
AR012504A1 (es) 2000-10-18
ES2222593T3 (es) 2005-02-01
NO995245L (no) 1999-12-27
JP2002501498A (ja) 2002-01-15
AU7436498A (en) 1998-11-24
CA2288241A1 (en) 1998-11-05
NO325163B1 (no) 2008-02-11
DE69824576D1 (de) 2004-07-22
JP3956059B2 (ja) 2007-08-08
BR9810234A (pt) 2000-09-19
EP0979079A1 (fr) 2000-02-16
DE69824576T2 (de) 2005-06-30
US6344464B1 (en) 2002-02-05
ATE269077T1 (de) 2004-07-15
FR2762514A1 (fr) 1998-10-30

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