ZA972894B - Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics. - Google Patents

Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics.

Info

Publication number: ZA972894B
Authority: ZA; South Africa
Prior art keywords: therapeutics; processes; preparation; diarylmethylidenefuran derivatives; diarylmethylidenefuran
Prior art date: 1996-04-04

Application number

ZA9702894A

Inventor

Eric Nicolai

Jean-Marie Teulon

Original Assignee

Union Pharma Scient Appl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-04

Filing date

1997-04-04

Publication date

1997-11-04

1997-04-04 Application filed by Union Pharma Scient Appl filed Critical Union Pharma Scient Appl

1997-11-04 Publication of ZA972894B publication Critical patent/ZA972894B/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Reproductive Health (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Furan Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

ZA9702894A 1996-04-04 1997-04-04 Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics. ZA972894B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9604236A FR2747123B1 (en)	1996-04-04	1996-04-04	NOVEL DIARYLMETHYLIDENE TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THERAPEUTIC USES

Publications (1)

Publication Number	Publication Date
ZA972894B true ZA972894B (en)	1997-11-04

Family

ID=9490907

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9702894A ZA972894B (en)	1996-04-04	1997-04-04	Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics.

Country Status (28)

Country	Link
EP (1)	EP0891345B1 (en)
JP (1)	JP2000508638A (en)
KR (1)	KR20000005146A (en)
CN (1)	CN1215396A (en)
AR (1)	AR006539A1 (en)
AT (1)	ATE204268T1 (en)
AU (1)	AU717146B2 (en)
BG (1)	BG62808B1 (en)
BR (1)	BR9708510A (en)
CA (1)	CA2248949A1 (en)
CZ (1)	CZ318898A3 (en)
DE (1)	DE69706157T2 (en)
DK (1)	DK0891345T3 (en)
EE (1)	EE03687B1 (en)
ES (1)	ES2162678T3 (en)
FR (2)	FR2747123B1 (en)
GE (1)	GEP20032924B (en)
IL (1)	IL126105A (en)
NO (1)	NO984624L (en)
NZ (1)	NZ331672A (en)
PL (1)	PL329213A1 (en)
PT (1)	PT891345E (en)
RU (1)	RU2189979C2 (en)
SI (1)	SI0891345T1 (en)
SK (1)	SK283292B6 (en)
TW (1)	TW353660B (en)
WO (1)	WO1997037984A1 (en)
ZA (1)	ZA972894B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6180651B1 (en) *	1996-04-04	2001-01-30	Bristol-Myers Squibb	Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
JP2001518087A (en) *	1997-04-02	2001-10-09	メルクフロストカナダアンドカンパニー	Α-Methylene-γ-lactones as selective cyclooxygenase-2 inhibitors
FR2775477B1 (en) *	1998-02-27	2000-05-19	Union Pharma Scient Appl	NOVEL HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES
CN1106392C (en) *	2000-10-24	2003-04-23	中国科学院上海有机化学研究所	Butenolide containing no substituent at beta position and its synthesis process
MXPA05004794A (en) *	2002-11-05	2005-08-19	Magnachem Int Lab Inc	Synthetic lactone formulations and method of use.
EP1692101B1 (en) *	2003-03-31	2011-07-06	Council of Scientific and Industrial Research	Mercapto-phenyl-naphthyl-methane derivatives and preparation thereof
ES2275218T3 (en)	2003-05-07	2007-06-01	Osteologix A/S	HYDROSOLUBLE STRONTIUM SALTS FOR THE TREATMENT OF CARTILAGOS AND / OR BONE AFFECTIONS.
US8779168B2 (en) *	2010-12-16	2014-07-15	Transitions Optical, Inc.	Lactone compounds and materials made therefrom
US20240165148A1 (en)	2021-03-15	2024-05-23	Saul Yedgar	Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2152792C (en) *	1993-01-15	2000-02-15	Stephen R. Bertenshaw	Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
US5474995A (en) *	1993-06-24	1995-12-12	Merck Frosst Canada, Inc.	Phenyl heterocycles as cox-2 inhibitors
US5585504A (en) *	1994-09-16	1996-12-17	Merck & Co., Inc.	Process of making cox-2 inhibitors having a lactone bridge

1996
- 1996-04-04 FR FR9604236A patent/FR2747123B1/en not_active Expired - Fee Related
- 1996-06-26 FR FR9607922A patent/FR2747124B1/en not_active Expired - Lifetime
1997
- 1997-03-24 TW TW086103701A patent/TW353660B/en active
- 1997-04-03 RU RU98119887/04A patent/RU2189979C2/en not_active IP Right Cessation
- 1997-04-03 CZ CZ983188A patent/CZ318898A3/en unknown
- 1997-04-03 AT AT97919476T patent/ATE204268T1/en active
- 1997-04-03 SI SI9730222T patent/SI0891345T1/en unknown
- 1997-04-03 IL IL12610597A patent/IL126105A/en not_active IP Right Cessation
- 1997-04-03 NZ NZ331672A patent/NZ331672A/en unknown
- 1997-04-03 PL PL97329213A patent/PL329213A1/en unknown
- 1997-04-03 SK SK1375-98A patent/SK283292B6/en not_active IP Right Cessation
- 1997-04-03 AU AU23933/97A patent/AU717146B2/en not_active Ceased
- 1997-04-03 WO PCT/FR1997/000602 patent/WO1997037984A1/en not_active Application Discontinuation
- 1997-04-03 DE DE69706157T patent/DE69706157T2/en not_active Expired - Lifetime
- 1997-04-03 JP JP9535910A patent/JP2000508638A/en active Pending
- 1997-04-03 GE GEAP19974555A patent/GEP20032924B/en unknown
- 1997-04-03 KR KR1019980707808A patent/KR20000005146A/en not_active Application Discontinuation
- 1997-04-03 CA CA002248949A patent/CA2248949A1/en not_active Abandoned
- 1997-04-03 PT PT97919476T patent/PT891345E/en unknown
- 1997-04-03 CN CN97193543A patent/CN1215396A/en active Pending
- 1997-04-03 EE EE9800333A patent/EE03687B1/en unknown
- 1997-04-03 ES ES97919476T patent/ES2162678T3/en not_active Expired - Lifetime
- 1997-04-03 BR BR9708510A patent/BR9708510A/en not_active IP Right Cessation
- 1997-04-03 DK DK97919476T patent/DK0891345T3/en active
- 1997-04-03 EP EP97919476A patent/EP0891345B1/en not_active Expired - Lifetime
- 1997-04-04 AR ARP970101359A patent/AR006539A1/en not_active Application Discontinuation
- 1997-04-04 ZA ZA9702894A patent/ZA972894B/en unknown
1998
- 1998-09-16 BG BG102771A patent/BG62808B1/en unknown
- 1998-10-02 NO NO984624A patent/NO984624L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
BG62808B1 (en)	2000-08-31
EE9800333A (en)	1999-04-15
FR2747123A1 (en)	1997-10-10
EE03687B1 (en)	2002-04-15
DE69706157T2 (en)	2002-04-11
ATE204268T1 (en)	2001-09-15
FR2747124A1 (en)	1997-10-10
GEP20032924B (en)	2003-03-25
PL329213A1 (en)	1999-03-15
RU2189979C2 (en)	2002-09-27
WO1997037984A1 (en)	1997-10-16
SI0891345T1 (en)	2002-02-28
AR006539A1 (en)	1999-09-08
FR2747124B1 (en)	1998-06-26
SK283292B6 (en)	2003-05-02
EP0891345A1 (en)	1999-01-20
TW353660B (en)	1999-03-01
CZ318898A3 (en)	1999-01-13
BR9708510A (en)	1999-08-03
AU717146B2 (en)	2000-03-16
PT891345E (en)	2002-02-28
EP0891345B1 (en)	2001-08-16
IL126105A (en)	2001-08-26
JP2000508638A (en)	2000-07-11
DK0891345T3 (en)	2001-12-03
BG102771A (en)	1999-06-30
NZ331672A (en)	2000-02-28
CA2248949A1 (en)	1997-10-16
KR20000005146A (en)	2000-01-25
AU2393397A (en)	1997-10-29
FR2747123B1 (en)	1998-06-26
CN1215396A (en)	1999-04-28
DE69706157D1 (en)	2001-09-20
NO984624L (en)	1998-11-30
NO984624D0 (en)	1998-10-02
IL126105A0 (en)	1999-05-09
ES2162678T3 (en)	2002-01-01
SK137598A3 (en)	1999-02-11

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