EE9800333A - Novel furanarylmethylidene derivatives, methods for their preparation and use in therapy - Google Patents

Novel furanarylmethylidene derivatives, methods for their preparation and use in therapy

Info

Publication number: EE9800333A
Authority: EE; Estonia
Prior art keywords: furanarylmethylidene; therapy; derivatives; novel; preparation
Prior art date: 1996-04-04

Application number

EE9800333A

Other languages

Estonian (et)

Other versions

EE03687B1 (en

Inventor

Nicolai Eric

Teulon Jean-Marie

Original Assignee

Laboratoires Upsa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-04

Filing date

1997-04-03

Publication date

1999-04-15

1997-04-03 Application filed by Laboratoires Upsa filed Critical Laboratoires Upsa

1999-04-15 Publication of EE9800333A publication Critical patent/EE9800333A/en

2002-04-15 Publication of EE03687B1 publication Critical patent/EE03687B1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

EE9800333A 1996-04-04 1997-04-03 Furandiarylmethylidene derivatives, method of their preparation and use in therapy EE03687B1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR9604236A FR2747123B1 (en)	1996-04-04	1996-04-04	NOVEL DIARYLMETHYLIDENE TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THERAPEUTIC USES
FR9607922A FR2747124B1 (en)	1996-04-04	1996-06-26	NOVEL FURANIC DIARYLMETHYLIDENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES
PCT/FR1997/000602 WO1997037984A1 (en)	1996-04-04	1997-04-03	Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof

Publications (2)

Publication Number	Publication Date
EE9800333A true EE9800333A (en)	1999-04-15
EE03687B1 EE03687B1 (en)	2002-04-15

Family

ID=9490907

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9800333A EE03687B1 (en)	1996-04-04	1997-04-03	Furandiarylmethylidene derivatives, method of their preparation and use in therapy

Country Status (28)

Country	Link
EP (1)	EP0891345B1 (en)
JP (1)	JP2000508638A (en)
KR (1)	KR20000005146A (en)
CN (1)	CN1215396A (en)
AR (1)	AR006539A1 (en)
AT (1)	ATE204268T1 (en)
AU (1)	AU717146B2 (en)
BG (1)	BG62808B1 (en)
BR (1)	BR9708510A (en)
CA (1)	CA2248949A1 (en)
CZ (1)	CZ318898A3 (en)
DE (1)	DE69706157T2 (en)
DK (1)	DK0891345T3 (en)
EE (1)	EE03687B1 (en)
ES (1)	ES2162678T3 (en)
FR (2)	FR2747123B1 (en)
GE (1)	GEP20032924B (en)
IL (1)	IL126105A (en)
NO (1)	NO984624L (en)
NZ (1)	NZ331672A (en)
PL (1)	PL329213A1 (en)
PT (1)	PT891345E (en)
RU (1)	RU2189979C2 (en)
SI (1)	SI0891345T1 (en)
SK (1)	SK283292B6 (en)
TW (1)	TW353660B (en)
WO (1)	WO1997037984A1 (en)
ZA (1)	ZA972894B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6180651B1 (en) *	1996-04-04	2001-01-30	Bristol-Myers Squibb	Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
WO1998043966A1 (en) *	1997-04-02	1998-10-08	Merck Frosst Canada & Co.	Alpha-methylene gamma lactones as selective cyclooxygenase-2 inhibitors
FR2775477B1 (en) *	1998-02-27	2000-05-19	Union Pharma Scient Appl	NOVEL HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES
CN1106392C (en) *	2000-10-24	2003-04-23	中国科学院上海有机化学研究所	Butenolide containing no substituent at beta position and its synthesis process
MXPA05004794A (en) *	2002-11-05	2005-08-19	Magnachem Int Lab Inc	Synthetic lactone formulations and method of use.
CN100569747C (en) *	2003-03-31	2009-12-16	科学与工业研究会	Sulfydryl-phenyl-naphthyl-methane Derivatives and preparation thereof
JP4354984B2 (en)	2003-05-07	2009-10-28	オステオロジックスエイ／エス	Treatment of cartilage / bone symptoms with water-soluble strontium salts
US8779168B2 (en) *	2010-12-16	2014-07-15	Transitions Optical, Inc.	Lactone compounds and materials made therefrom
WO2022195579A1 (en)	2021-03-15	2022-09-22	Saul Yedgar	Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994015932A1 (en) *	1993-01-15	1994-07-21	G.D. Searle & Co.	Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
US5474995A (en) *	1993-06-24	1995-12-12	Merck Frosst Canada, Inc.	Phenyl heterocycles as cox-2 inhibitors
US5585504A (en) *	1994-09-16	1996-12-17	Merck & Co., Inc.	Process of making cox-2 inhibitors having a lactone bridge

1996
- 1996-04-04 FR FR9604236A patent/FR2747123B1/en not_active Expired - Fee Related
- 1996-06-26 FR FR9607922A patent/FR2747124B1/en not_active Expired - Lifetime
1997
- 1997-03-24 TW TW086103701A patent/TW353660B/en active
- 1997-04-03 NZ NZ331672A patent/NZ331672A/en unknown
- 1997-04-03 JP JP9535910A patent/JP2000508638A/en active Pending
- 1997-04-03 IL IL12610597A patent/IL126105A/en not_active IP Right Cessation
- 1997-04-03 GE GEAP19974555A patent/GEP20032924B/en unknown
- 1997-04-03 SK SK1375-98A patent/SK283292B6/en not_active IP Right Cessation
- 1997-04-03 CN CN97193543A patent/CN1215396A/en active Pending
- 1997-04-03 PT PT97919476T patent/PT891345E/en unknown
- 1997-04-03 CZ CZ983188A patent/CZ318898A3/en unknown
- 1997-04-03 WO PCT/FR1997/000602 patent/WO1997037984A1/en not_active Application Discontinuation
- 1997-04-03 EP EP97919476A patent/EP0891345B1/en not_active Expired - Lifetime
- 1997-04-03 RU RU98119887/04A patent/RU2189979C2/en not_active IP Right Cessation
- 1997-04-03 EE EE9800333A patent/EE03687B1/en unknown
- 1997-04-03 DK DK97919476T patent/DK0891345T3/en active
- 1997-04-03 DE DE69706157T patent/DE69706157T2/en not_active Expired - Lifetime
- 1997-04-03 AT AT97919476T patent/ATE204268T1/en active
- 1997-04-03 KR KR1019980707808A patent/KR20000005146A/en not_active Application Discontinuation
- 1997-04-03 SI SI9730222T patent/SI0891345T1/en unknown
- 1997-04-03 PL PL97329213A patent/PL329213A1/en unknown
- 1997-04-03 AU AU23933/97A patent/AU717146B2/en not_active Ceased
- 1997-04-03 ES ES97919476T patent/ES2162678T3/en not_active Expired - Lifetime
- 1997-04-03 CA CA002248949A patent/CA2248949A1/en not_active Abandoned
- 1997-04-03 BR BR9708510A patent/BR9708510A/en not_active IP Right Cessation
- 1997-04-04 AR ARP970101359A patent/AR006539A1/en not_active Application Discontinuation
- 1997-04-04 ZA ZA9702894A patent/ZA972894B/en unknown
1998
- 1998-09-16 BG BG102771A patent/BG62808B1/en unknown
- 1998-10-02 NO NO984624A patent/NO984624L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU717146B2 (en)	2000-03-16
KR20000005146A (en)	2000-01-25
EE03687B1 (en)	2002-04-15
PL329213A1 (en)	1999-03-15
FR2747123B1 (en)	1998-06-26
WO1997037984A1 (en)	1997-10-16
SI0891345T1 (en)	2002-02-28
FR2747124B1 (en)	1998-06-26
SK283292B6 (en)	2003-05-02
NO984624L (en)	1998-11-30
EP0891345A1 (en)	1999-01-20
CA2248949A1 (en)	1997-10-16
CZ318898A3 (en)	1999-01-13
EP0891345B1 (en)	2001-08-16
AR006539A1 (en)	1999-09-08
BG62808B1 (en)	2000-08-31
GEP20032924B (en)	2003-03-25
PT891345E (en)	2002-02-28
ES2162678T3 (en)	2002-01-01
IL126105A0 (en)	1999-05-09
DE69706157D1 (en)	2001-09-20
ATE204268T1 (en)	2001-09-15
CN1215396A (en)	1999-04-28
IL126105A (en)	2001-08-26
FR2747124A1 (en)	1997-10-10
DE69706157T2 (en)	2002-04-11
FR2747123A1 (en)	1997-10-10
JP2000508638A (en)	2000-07-11
TW353660B (en)	1999-03-01
NO984624D0 (en)	1998-10-02
ZA972894B (en)	1997-11-04
AU2393397A (en)	1997-10-29
BR9708510A (en)	1999-08-03
BG102771A (en)	1999-06-30
DK0891345T3 (en)	2001-12-03
SK137598A3 (en)	1999-02-11
NZ331672A (en)	2000-02-28
RU2189979C2 (en)	2002-09-27

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231

Publication	Publication Date	Title
EE03231B1 (en)	1999-10-15	Tetracyclic derivatives, process for their preparation and use
EE9900147A (en)	1999-12-15	Oxadiazoles, methods for their preparation and use as pharmaceuticals
EE9800459A (en)	1999-06-15	Spiro-piperidine derivatives and their use as therapeutic agents
FI944600A (en)	1995-04-05	Imidazol-4-ylpiperidine derivatives, their preparation and their use in therapy
FI955913A0 (en)	1995-12-08	New erythromycin derivatives, methods for their preparation and their use as drugs
FI955235A0 (en)	1995-11-01	Oxazolidinedione derivatives, their preparation and use
EE9700039A (en)	1997-08-15	Spiro-azabicyclic compounds used in therapy and their preparation process
EE03482B1 (en)	2001-08-15	Quinazoline derivatives, process for their preparation and use
EE03568B1 (en)	2001-12-17	Benzimidazole derivatives, process for their preparation and use
CY2013003I1 (en)	2014-07-02	PHOSPHONOCHEMICAL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF
EE9600172A (en)	1997-06-16	Purin-6-one derivatives, their preparation method, use in the preparation of medicaments and medicaments
EE9800302A (en)	1999-02-15	Arylglycinamide derivatives, process for their preparation and use, and pharmaceutical preparation
EE9700288A (en)	1998-04-15	Azacycloalkane derivatives, their preparation and use in therapy
EE9900155A (en)	1999-12-15	1H-pyrido [3,4-b] indole-4-carboxamide derivatives, process for their preparation and use in therapy
EE9900218A (en)	1999-12-15	1,4-Diazabicyclo [2.2.2] oct-2-ylmethyl benzoate derivatives, their preparation and their use in therapy
EE9800145A (en)	1998-10-15	Phenylamidine derivatives, methods for their preparation and their use as medicaments
EE200000056A (en)	2000-10-16	4-Oxo-3,5-dihydro-4H-pyridazino [4.5-b] indole-1-ethanamide derivatives, their preparation and their use in therapy
DK1025100T3 (en)	2002-05-06	3-substituted tetrahydropyridopyrimidinone derivatives, their preparation and their use
EE9800333A (en)	1999-04-15	Novel furanarylmethylidene derivatives, methods for their preparation and use in therapy
FI941914A (en)	1994-10-28	2-amino-4-quinoline dihydropyridines, methods for their preparation and their use
FI940186A (en)	1994-07-16	9H-Imidazo [1,2-a] benzimidazole-3-acetamide derivatives, their preparation and their use in therapy
EE9900135A (en)	1999-12-15	N- (2-benzothiazolyl) -1-piperidinethanamine derivatives, their preparation and their use in therapy
EE9900414A (en)	2000-04-17	2,3-dihydrofuro [3,2-b] pyridine derivatives, their preparation and use in therapy
EE200000207A (en)	2001-04-16	8-Azabicyclo [3.2.1] octane-3-methanamine derivatives, their preparation and therapeutic use
FI971317A0 (en)	1997-03-27	New heterocyclic, substituted imidazoloquinoxalinones, their preparation and use