ZA964764B - (R)-(Z)-1-Azabicyclo ¬2.2.1¾ heptan-3-one 0-¬3-(3-methoxy-phenyl)-2-propynyl¾ oxime maleate as a pharmaceutical agent - Google Patents
(R)-(Z)-1-Azabicyclo ¬2.2.1¾ heptan-3-one 0-¬3-(3-methoxy-phenyl)-2-propynyl¾ oxime maleate as a pharmaceutical agentInfo
- Publication number
- ZA964764B ZA964764B ZA964764A ZA964764A ZA964764B ZA 964764 B ZA964764 B ZA 964764B ZA 964764 A ZA964764 A ZA 964764A ZA 964764 A ZA964764 A ZA 964764A ZA 964764 B ZA964764 B ZA 964764B
- Authority
- ZA
- South Africa
- Prior art keywords
- heptan
- azabicyclo
- methoxy
- phenyl
- pharmaceutical agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/474,622 US5534522A (en) | 1995-06-07 | 1995-06-07 | (R)-(Z)-1-azabicyclo [2.2.1] heptan-3-one,O-[3-(3-methoxyphenyl)-2-propynyl] oxime maleate as a pharmaceutical agent |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA964764B true ZA964764B (en) | 1997-01-08 |
Family
ID=23884337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA964764A ZA964764B (en) | 1995-06-07 | 1996-06-06 | (R)-(Z)-1-Azabicyclo ¬2.2.1¾ heptan-3-one 0-¬3-(3-methoxy-phenyl)-2-propynyl¾ oxime maleate as a pharmaceutical agent |
Country Status (25)
Country | Link |
---|---|
US (1) | US5534522A (xx) |
EP (1) | EP0839148B1 (xx) |
JP (1) | JPH11506723A (xx) |
KR (1) | KR100383031B1 (xx) |
CN (1) | CN1063181C (xx) |
AT (1) | ATE187967T1 (xx) |
BG (1) | BG63571B1 (xx) |
CA (1) | CA2219753A1 (xx) |
CZ (1) | CZ286528B6 (xx) |
DE (1) | DE69605800T2 (xx) |
DK (1) | DK0839148T3 (xx) |
EA (1) | EA000381B1 (xx) |
EE (1) | EE03971B1 (xx) |
ES (1) | ES2142586T3 (xx) |
GE (1) | GEP19991874B (xx) |
GR (1) | GR3032772T3 (xx) |
HK (1) | HK1018055A1 (xx) |
HU (1) | HUP9802499A3 (xx) |
NO (1) | NO308901B1 (xx) |
NZ (1) | NZ307946A (xx) |
PL (1) | PL323796A1 (xx) |
SK (1) | SK282824B6 (xx) |
UA (1) | UA46032C2 (xx) |
WO (1) | WO1996040687A1 (xx) |
ZA (1) | ZA964764B (xx) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9601909A (pt) * | 1995-07-13 | 1999-10-13 | Smithkline Beecham Corp | N,n-dietil-8,8-dipropil-2-azaspiro(4,5)decano-2-propan amina dimaleato |
US6528529B1 (en) | 1998-03-31 | 2003-03-04 | Acadia Pharmaceuticals Inc. | Compounds with activity on muscarinic receptors |
US7544681B2 (en) | 2001-09-27 | 2009-06-09 | Ramot At Tel Aviv University Ltd. | Conjugated psychotropic drugs and uses thereof |
JP4933259B2 (ja) * | 2003-10-02 | 2012-05-16 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | ピロール置換インドリノン化合物の塩および多形 |
US7741358B2 (en) * | 2005-04-14 | 2010-06-22 | N.V. Organon | Crystal form of asenapine maleate |
MX2007015511A (es) * | 2005-06-07 | 2008-03-06 | Univ Ramot | Sales novedosas de farmacos sicotropicos conjugados y procesos para prepararlas. |
EP2275095A3 (en) | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス,インコーポレイティド | Pde阻害による神経新生の調節 |
CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
WO2007134136A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
AU2007249435A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
EP2051735B1 (en) | 2006-07-17 | 2012-08-29 | Ramot, at Tel Aviv University Ltd. | Conjugates comprising a psychotropic drug or a gaba agonist and an organic acid and their use treating pain and other cns disorders |
KR20090064418A (ko) | 2006-09-08 | 2009-06-18 | 브레인셀즈 인코퍼레이션 | 4-아실아미노피리딘 유도체 포함 조합물 |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
WO2009101616A1 (en) | 2008-02-11 | 2009-08-20 | Ramot At Tel Aviv University Ltd. | Novel conjugates for treating neurodegenerative diseases and disorders |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
AU2010329440A1 (en) | 2009-12-09 | 2012-08-09 | Bar-Ilan University | Methods of improving cognitive functions |
AU2011219529A1 (en) | 2010-02-24 | 2012-08-30 | Bar-Ilan University | Crystalline forms of the tri-mesylate salt of perphenazine-GABA and process of producing the same |
WO2012038963A1 (en) | 2010-09-22 | 2012-03-29 | Ramot At Tel-Aviv University Ltd. | An acid addition salt of a nortriptyline-gaba conjugate and a process of preparing same |
JP5997931B2 (ja) * | 2011-05-25 | 2016-09-28 | 石原産業株式会社 | 農園芸用殺菌剤組成物及び植物病害の防除方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5306718A (en) * | 1990-03-06 | 1994-04-26 | Warner-Lambert Company | Oxime and amine substituted azabicyclo and azocyclo muscarinic agonists and methods of treatment |
US5346911A (en) * | 1990-03-06 | 1994-09-13 | Warner-Lambert Company | Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment |
-
1995
- 1995-06-07 US US08/474,622 patent/US5534522A/en not_active Expired - Fee Related
-
1996
- 1996-05-13 UA UA98010040A patent/UA46032C2/uk unknown
- 1996-05-13 KR KR1019970709053A patent/KR100383031B1/ko not_active IP Right Cessation
- 1996-05-13 PL PL96323796A patent/PL323796A1/xx unknown
- 1996-05-13 CZ CZ19973817A patent/CZ286528B6/cs not_active IP Right Cessation
- 1996-05-13 EA EA199800007A patent/EA000381B1/ru not_active IP Right Cessation
- 1996-05-13 ES ES96915757T patent/ES2142586T3/es not_active Expired - Lifetime
- 1996-05-13 CN CN96194436A patent/CN1063181C/zh not_active Expired - Fee Related
- 1996-05-13 GE GEAP19964088A patent/GEP19991874B/en unknown
- 1996-05-13 SK SK1644-97A patent/SK282824B6/sk unknown
- 1996-05-13 DK DK96915757T patent/DK0839148T3/da active
- 1996-05-13 DE DE69605800T patent/DE69605800T2/de not_active Expired - Fee Related
- 1996-05-13 AT AT96915757T patent/ATE187967T1/de not_active IP Right Cessation
- 1996-05-13 HU HU9802499A patent/HUP9802499A3/hu unknown
- 1996-05-13 EE EE9700316A patent/EE03971B1/xx not_active IP Right Cessation
- 1996-05-13 NZ NZ307946A patent/NZ307946A/en unknown
- 1996-05-13 WO PCT/US1996/006814 patent/WO1996040687A1/en active IP Right Grant
- 1996-05-13 CA CA002219753A patent/CA2219753A1/en not_active Abandoned
- 1996-05-13 EP EP96915757A patent/EP0839148B1/en not_active Expired - Lifetime
- 1996-05-13 JP JP9500555A patent/JPH11506723A/ja active Pending
- 1996-06-06 ZA ZA964764A patent/ZA964764B/xx unknown
-
1997
- 1997-11-27 BG BG102078A patent/BG63571B1/bg unknown
- 1997-12-05 NO NO975704A patent/NO308901B1/no not_active IP Right Cessation
-
1998
- 1998-12-15 HK HK98113383A patent/HK1018055A1/xx not_active IP Right Cessation
-
2000
- 2000-02-28 GR GR20000400474T patent/GR3032772T3/el not_active IP Right Cessation
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