ZA937505B - Imidazopyridine derivatives as 5-HT4 receptor antagonists - Google Patents

Imidazopyridine derivatives as 5-HT4 receptor antagonists

Info

Publication number
ZA937505B
ZA937505B ZA937505A ZA937505A ZA937505B ZA 937505 B ZA937505 B ZA 937505B ZA 937505 A ZA937505 A ZA 937505A ZA 937505 A ZA937505 A ZA 937505A ZA 937505 B ZA937505 B ZA 937505B
Authority
ZA
South Africa
Prior art keywords
receptor antagonists
imidazopyridine derivatives
imidazopyridine
derivatives
antagonists
Prior art date
Application number
ZA937505A
Inventor
Francis David King
Laramie Mary Gaster
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of ZA937505B publication Critical patent/ZA937505B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
ZA937505A 1992-10-13 1993-10-11 Imidazopyridine derivatives as 5-HT4 receptor antagonists ZA937505B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929221468A GB9221468D0 (en) 1992-10-13 1992-10-13 Pharmaceuticals

Publications (1)

Publication Number Publication Date
ZA937505B true ZA937505B (en) 1994-07-22

Family

ID=10723359

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA937505A ZA937505B (en) 1992-10-13 1993-10-11 Imidazopyridine derivatives as 5-HT4 receptor antagonists

Country Status (9)

Country Link
EP (1) EP0664808A1 (en)
JP (1) JPH08502274A (en)
CN (1) CN1092775A (en)
AU (1) AU5177093A (en)
CA (1) CA2146928A1 (en)
GB (1) GB9221468D0 (en)
MX (1) MX9306310A (en)
WO (1) WO1994008998A1 (en)
ZA (1) ZA937505B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
US5998409A (en) * 1992-03-12 1999-12-07 Smithkline Beecham Plc Condensed indole derivatives as 5HT4 -receptor antagonists
EP0664794A1 (en) * 1992-10-16 1995-08-02 Smithkline Beecham Plc N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-ht4 receptor antagonists
WO1997029739A2 (en) * 1996-02-15 1997-08-21 Janssen Pharmaceutica N.V. Use of 5ht4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhibitors
FR2797630B1 (en) * 1999-08-20 2005-04-29 Univ Caen Basse Normandie PYRROLO [1,2-a] QUINOXALINE ETHER DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC APPLICATION
BR0213026A (en) * 2001-10-22 2004-10-05 Pfizer Imidazopyridine Compounds as 5-ht4 Receptor Regulators
US6624162B2 (en) 2001-10-22 2003-09-23 Pfizer Inc. Imidazopyridine compounds as 5-HT4 receptor modulators
MXPA03000145A (en) 2002-01-07 2003-07-15 Pfizer Oxo or oxy-pyridine compounds as 5-ht4 receptor modulators.
GB0211230D0 (en) 2002-05-16 2002-06-26 Medinnova Sf Treatment of heart failure
DOP2003000703A (en) 2002-09-20 2004-03-31 Pfizer IMIDAZOPIRADINE COMPOUNDS AS 5-HT4 RECEIVER AGONISTS
EP1543004A1 (en) * 2002-09-20 2005-06-22 Pfizer Inc. N-substituted piperidinyl-imidazopyridine compounds as 5-ht4 receptor modulators
MXPA05011270A (en) * 2003-04-21 2006-01-24 Pfizer Imadazopyridine compounds having 5-ht4.
WO2005123718A2 (en) 2004-06-15 2005-12-29 Pfizer Japan Inc. Benzimidazolone carboxylic acid derivatives
US7737163B2 (en) 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
CN104725376A (en) * 2015-03-31 2015-06-24 山东友帮生化科技有限公司 Synthetic method of 6-chlorine-8-carboxyl imidazo [1,2-a] pyridine
CN104761551A (en) * 2015-03-31 2015-07-08 山东友帮生化科技有限公司 Method for synthesizing 6-iodo-8-carboxylimidazo(1,2-a)pyridine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9103862D0 (en) * 1991-02-25 1991-04-10 Glaxo Group Ltd Chemical compounds
US5260303A (en) * 1991-03-07 1993-11-09 G. D. Searle & Co. Imidazopyridines as serotonergic 5-HT3 antagonists

Also Published As

Publication number Publication date
EP0664808A1 (en) 1995-08-02
CA2146928A1 (en) 1994-04-28
CN1092775A (en) 1994-09-28
JPH08502274A (en) 1996-03-12
GB9221468D0 (en) 1992-11-25
WO1994008998A1 (en) 1994-04-28
AU5177093A (en) 1994-05-09
MX9306310A (en) 1994-04-29

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