ZA926968B - A tramadol N-oxide material enantiomers and compositions thereof and their use - Google Patents

A tramadol N-oxide material enantiomers and compositions thereof and their use

Info

Publication number: ZA926968B
Authority: ZA; South Africa
Prior art keywords: tramadol; compositions; oxide material; enantiomers; oxide
Prior art date: 1991-09-13

Application number

ZA926968A

Other languages

English (en)

Inventor

Cynthia A Maryanoff

Robert B Raffa

Frank J Villani

Original Assignee

Mcneilab Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-13

Filing date

1992-09-11

Publication date

1994-03-11

1992-09-11 Application filed by Mcneilab Inc filed Critical Mcneilab Inc

1994-03-11 Publication of ZA926968B publication Critical patent/ZA926968B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
- C07C291/04—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds containing amino-oxide bonds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Catching Or Destruction (AREA)
Cosmetics (AREA)

ZA926968A 1991-09-13 1992-09-11 A tramadol N-oxide material enantiomers and compositions thereof and their use ZA926968B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/759,259 US5223541A (en)	1991-09-13	1991-09-13	Tramadol n-oxide material, enantiomers and compositions thereof, and their use

Publications (1)

Publication Number	Publication Date
ZA926968B true ZA926968B (en)	1994-03-11

Family

ID=25054992

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA926968A ZA926968B (en)	1991-09-13	1992-09-11	A tramadol N-oxide material enantiomers and compositions thereof and their use

Country Status (23)

Country	Link
US (1)	US5223541A (hu)
EP (1)	EP0532348B1 (hu)
JP (1)	JP3115119B2 (hu)
KR (1)	KR100241859B1 (hu)
CN (1)	CN1032533C (hu)
AT (1)	ATE132852T1 (hu)
AU (1)	AU651000B2 (hu)
CA (1)	CA2078028C (hu)
DE (1)	DE69207526T2 (hu)
DK (1)	DK0532348T3 (hu)
ES (1)	ES2086079T3 (hu)
FI (1)	FI111717B (hu)
GR (1)	GR3019345T3 (hu)
HU (1)	HU214321B (hu)
IL (1)	IL103154A (hu)
MX (1)	MX9205219A (hu)
MY (1)	MY121910A (hu)
NO (1)	NO178105C (hu)
NZ (1)	NZ244309A (hu)
SG (1)	SG63550A1 (hu)
TW (1)	TW221968B (hu)
ZA (1)	ZA926968B (hu)
ZW (1)	ZW14592A1 (hu)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0566709B3 (en)	1991-09-06	2009-04-08	Ortho-McNeil-Janssen Pharmaceuticals, Inc.	Composition comprising a tramadol compound and acetaminophen, and its use
US5958459A (en) *	1991-12-24	1999-09-28	Purdue Pharma L.P.	Opioid formulations having extended controlled released
US5478577A (en) *	1993-11-23	1995-12-26	Euroceltique, S.A.	Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5968551A (en) *	1991-12-24	1999-10-19	Purdue Pharma L.P.	Orally administrable opioid formulations having extended duration of effect
IL110014A (en)	1993-07-01	1999-11-30	Euro Celtique Sa	Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en)	1993-07-01	2010-06-22	Purdue Pharma Lp	Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) *	1993-07-27	1999-03-09	Euro-Celtique S.A.	Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US6017963A (en) *	1995-11-14	2000-01-25	Euro-Celtique, S.A.	Formulation for intranasal administration
IE980512A1 (en)	1997-07-15	1999-10-20	Russinsky Ltd	A product and process
US6156342A (en) *	1998-05-26	2000-12-05	Andex Pharmaceuticals, Inc.	Controlled release oral dosage form
US6806294B2 (en)	1998-10-15	2004-10-19	Euro-Celtique S.A.	Opioid analgesic
ATE526950T1 (de)	1999-10-29	2011-10-15	Euro Celtique Sa	Hydrocodon-formulierungen mit gesteuerter freisetzung
US10179130B2 (en)	1999-10-29	2019-01-15	Purdue Pharma L.P.	Controlled release hydrocodone formulations
DE10000312A1 (de) *	2000-01-05	2001-07-12	Gruenenthal Gmbh	Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
CA2427815C (en)	2000-10-30	2007-07-10	Euro-Celtique S.A.	Controlled release hydrocodone formulations
CA2758923A1 (en)	2001-03-16	2002-09-26	Dmi Biosciences, Inc.	Use of tramadol to delay ejaculation
UA81224C2 (uk)	2001-05-02	2007-12-25	Euro Celtic S A	Дозована форма оксикодону та її застосування
US20110104214A1 (en)	2004-04-15	2011-05-05	Purdue Pharma L.P.	Once-a-day oxycodone formulations
US6649783B2 (en) *	2001-10-03	2003-11-18	Euro-Celtique, S.A.	Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
AU2002364517A1 (en)	2001-11-30	2003-06-17	Sepracor Inc.	Tramadol analogs and uses thereof
US9092841B2 (en)	2004-06-09	2015-07-28	Cognex Technology And Investment Llc	Method and apparatus for visual detection and inspection of objects
US7940687B2 (en)	2005-11-16	2011-05-10	Qualcomm Incorporated	Efficient partitioning of control and data fields
WO2008100926A1 (en)	2007-02-12	2008-08-21	Dmi Biosciences, Inc.	Treatment of comorbid premature ejaculation and erectile dysfunction
US20080261991A1 (en)	2007-02-12	2008-10-23	Dmi Biosciences, Inc.	Reducing Side Effects of Tramadol
WO2009000797A1 (en) *	2007-06-26	2008-12-31	Solvay Pharmaceuticals B.V.	N-oxides of venlafaxine and o-desmethylvenlafaxine as prodrugs
US20100003322A1 (en) *	2008-07-03	2010-01-07	Lai Felix S	Enteric coated hydrophobic matrix formulation
US10475492B1 (en)	2018-07-27	2019-11-12	Macronix International Co., Ltd.	Circuit and method for read latency control

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3652589A (en) *	1967-07-27	1972-03-28	Gruenenthal Chemie	1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
US4017637A (en) *	1973-03-26	1977-04-12	American Home Products Corporation	Benzylamine analgesics
DE3515349A1 (de) *	1985-04-27	1986-10-30	Messerschmitt-Bölkow-Blohm GmbH, 8012 Ottobrunn	Elektrischer geber zur messung mechanischer groessen

1991
- 1991-09-13 US US07/759,259 patent/US5223541A/en not_active Expired - Lifetime
1992
- 1992-09-11 NO NO923530A patent/NO178105C/no not_active IP Right Cessation
- 1992-09-11 EP EP92308298A patent/EP0532348B1/en not_active Expired - Lifetime
- 1992-09-11 DK DK92308298.6T patent/DK0532348T3/da active
- 1992-09-11 AT AT92308298T patent/ATE132852T1/de active
- 1992-09-11 ZA ZA926968A patent/ZA926968B/xx unknown
- 1992-09-11 DE DE69207526T patent/DE69207526T2/de not_active Expired - Lifetime
- 1992-09-11 AU AU23557/92A patent/AU651000B2/en not_active Expired
- 1992-09-11 SG SG1996001523A patent/SG63550A1/en unknown
- 1992-09-11 MX MX9205219A patent/MX9205219A/es unknown
- 1992-09-11 FI FI924084A patent/FI111717B/fi not_active IP Right Cessation
- 1992-09-11 HU HU9202918A patent/HU214321B/hu unknown
- 1992-09-11 NZ NZ244309A patent/NZ244309A/en not_active IP Right Cessation
- 1992-09-11 CA CA002078028A patent/CA2078028C/en not_active Expired - Lifetime
- 1992-09-11 CN CN92111582A patent/CN1032533C/zh not_active Expired - Lifetime
- 1992-09-11 ES ES92308298T patent/ES2086079T3/es not_active Expired - Lifetime
- 1992-09-12 MY MYPI92001635A patent/MY121910A/en unknown
- 1992-09-13 IL IL10315492A patent/IL103154A/en not_active IP Right Cessation
- 1992-09-14 ZW ZW14592A patent/ZW14592A1/xx unknown
- 1992-09-14 KR KR1019920016819A patent/KR100241859B1/ko not_active IP Right Cessation
- 1992-09-14 JP JP04269183A patent/JP3115119B2/ja not_active Expired - Lifetime
- 1992-11-10 TW TW081108968A patent/TW221968B/zh not_active IP Right Cessation
1996
- 1996-03-19 GR GR960400740T patent/GR3019345T3/el unknown

Also Published As

Publication number	Publication date
GR3019345T3 (en)	1996-06-30
HU214321B (hu)	1998-03-02
FI924084A0 (fi)	1992-09-11
KR930005969A (ko)	1993-04-20
IL103154A (en)	1996-09-12
FI924084A (fi)	1993-03-14
IL103154A0 (en)	1993-02-21
AU2355792A (en)	1993-03-18
NO923530D0 (no)	1992-09-11
JPH06122668A (ja)	1994-05-06
NO923530L (no)	1993-03-15
EP0532348B1 (en)	1996-01-10
ATE132852T1 (de)	1996-01-15
CA2078028A1 (en)	1993-03-14
DK0532348T3 (da)	1996-02-05
FI111717B (fi)	2003-09-15
NO178105B (no)	1995-10-16
ZW14592A1 (en)	1994-05-11
MX9205219A (es)	1994-02-28
EP0532348A2 (en)	1993-03-17
DE69207526D1 (de)	1996-02-22
NZ244309A (en)	1994-10-26
ES2086079T3 (es)	1996-06-16
MY121910A (en)	2006-03-31
CN1032533C (zh)	1996-08-14
DE69207526T2 (de)	1996-07-04
EP0532348A3 (en)	1993-05-26
SG63550A1 (en)	1999-03-30
HU9202918D0 (en)	1992-11-30
NO178105C (no)	1996-01-24
HUT65476A (en)	1994-06-28
CA2078028C (en)	2003-04-29
KR100241859B1 (ko)	2000-02-01
AU651000B2 (en)	1994-07-07
TW221968B (hu)	1994-04-01
JP3115119B2 (ja)	2000-12-04
US5223541A (en)	1993-06-29
CN1071913A (zh)	1993-05-12

Publication	Publication Date	Title
TW221968B (hu)	1994-04-01
IL103594A0 (en)	1993-03-15	Compositions comprising a tramadol material and a nonsteroidal anti-inflammatory drug
CA2095523A1 (en)	1993-03-07	Composition comprising a tramadol material and acetaminophen and its use
MY110317A (en)	1998-04-30	Compositions comprising a tramadol material and any of codeine, oxycodone or hydrocodone, and their use.
MY114755A (en)	2003-01-31	Composition comprising a tramadol material and acetaminophen and its use.