ZA903409B - Maleinimide-derivatives and their use as pharmaceuticals - Google Patents

Maleinimide-derivatives and their use as pharmaceuticals

Info

Publication number
ZA903409B
ZA903409B ZA903409A ZA903409A ZA903409B ZA 903409 B ZA903409 B ZA 903409B ZA 903409 A ZA903409 A ZA 903409A ZA 903409 A ZA903409 A ZA 903409A ZA 903409 B ZA903409 B ZA 903409B
Authority
ZA
South Africa
Prior art keywords
maleinimide
pharmaceuticals
derivatives
Prior art date
Application number
ZA903409A
Inventor
Hubert Barth
Barth Hubert
Johannes Hartenstein
Hartenstein Johannes
Claus Rudolph
Rudolph Claus
Christoph Schaechtele
Schaechtele Christoph
Hans-Juergen Betche
Betche Hans-Juergen
Hartmut Osswald
Osswald Hartmut
Reinhard Reck
Reck Reinhard
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of ZA903409B publication Critical patent/ZA903409B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
ZA903409A 1989-05-05 1990-05-04 Maleinimide-derivatives and their use as pharmaceuticals ZA903409B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3914764A DE3914764A1 (en) 1989-05-05 1989-05-05 New bis(1H-indol-3-yl) maleinimide derivs. - are inhibitors of protein kinase C for treatment of cardiovascular, CNS and immune system disorders

Publications (1)

Publication Number Publication Date
ZA903409B true ZA903409B (en) 1991-02-27

Family

ID=6380102

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA903409A ZA903409B (en) 1989-05-05 1990-05-04 Maleinimide-derivatives and their use as pharmaceuticals

Country Status (3)

Country Link
DD (1) DD297970A5 (en)
DE (1) DE3914764A1 (en)
ZA (1) ZA903409B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3761393A (en) * 1992-03-20 1993-10-21 Wellcome Foundation Limited, The Indole derivatives with antiviral activity
US5405864A (en) * 1993-10-15 1995-04-11 Syntex (U.S.A.) Inc. Chemotherapeutic maleimides
US5723456A (en) * 1993-12-07 1998-03-03 Eli Lilly & Company Therapeutic treatment for cardiovascular diseases
IL111851A (en) * 1993-12-07 1998-09-24 Lilly Co Eli Intermediates useful in the synthesis of bisindolylmaleimides and process for their preparation
CN1050844C (en) * 1993-12-07 2000-03-29 伊莱利利公司 Protein kinase C inhibitors
US5541347A (en) * 1993-12-07 1996-07-30 Eli Lilly And Company Synthesis of bisindolylmaleimides
US5624949A (en) * 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
SI0817627T1 (en) * 1993-12-23 2005-08-31 Lilly Co Eli
US5481003A (en) * 1994-06-22 1996-01-02 Eli Lilly And Company Protein kinase C inhibitors
US5491242A (en) * 1994-06-22 1996-02-13 Eli Lilly And Company Protein kinase C inhibitors
US5559228A (en) * 1995-03-30 1996-09-24 Eli Lilly And Company Synthesis of bisindolylmaleimides
TW201041580A (en) 2001-09-27 2010-12-01 Alcon Inc Inhibitors of glycogen synthase kinase-3 (GSK-3) for treating glaucoma
DE10244453A1 (en) * 2002-09-24 2004-04-01 Phenomiques Gmbh Inhibition of the protein kinase C-alpha for the treatment of diseases
WO2016008966A1 (en) 2014-07-17 2016-01-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for treating neuromuscular junction-related diseases
WO2016207366A1 (en) 2015-06-26 2016-12-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of viral infections

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ280738B6 (en) * 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituted pyrroles, their use for preparing medicaments and medicaments based thereon

Also Published As

Publication number Publication date
DE3914764A1 (en) 1990-11-08
DD297970A5 (en) 1992-01-30

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