ZA898074B - Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism - Google Patents
Use of bicyclic imidazole compounds for the treatment of hyperaldosteronismInfo
- Publication number
- ZA898074B ZA898074B ZA898074A ZA898074A ZA898074B ZA 898074 B ZA898074 B ZA 898074B ZA 898074 A ZA898074 A ZA 898074A ZA 898074 A ZA898074 A ZA 898074A ZA 898074 B ZA898074 B ZA 898074B
- Authority
- ZA
- South Africa
- Prior art keywords
- hyperaldosteronism
- treatment
- imidazole compounds
- compounds
- bicyclic imidazole
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH399488 | 1988-10-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA898074B true ZA898074B (en) | 1990-08-29 |
Family
ID=4267831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA898074A ZA898074B (en) | 1988-10-26 | 1989-10-25 | Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism |
Country Status (12)
Country | Link |
---|---|
US (1) | US5057521A (xx) |
EP (1) | EP0366609B1 (xx) |
JP (1) | JPH02169518A (xx) |
KR (1) | KR900005976A (xx) |
AT (1) | ATE104852T1 (xx) |
AU (1) | AU631814B2 (xx) |
CA (1) | CA2001301A1 (xx) |
DE (1) | DE58907570D1 (xx) |
DK (1) | DK531089A (xx) |
IE (1) | IE63481B1 (xx) |
IL (1) | IL92078A (xx) |
ZA (1) | ZA898074B (xx) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH683151A5 (de) * | 1991-04-24 | 1994-01-31 | Ciba Geigy Ag | Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus. |
US6333335B1 (en) | 1999-07-23 | 2001-12-25 | Merck & Co., Inc. | Phenyl-protein transferase inhibitors |
US20030083342A1 (en) * | 2002-08-27 | 2003-05-01 | Steele Ronald Edward | Combination of organic compounds |
CN1900079A (zh) * | 2000-11-17 | 2007-01-24 | 武田药品工业株式会社 | 新咪唑衍生物、其制备方法及其用途 |
WO2005118581A1 (en) | 2004-05-28 | 2005-12-15 | Speedel Experimenta Ag | Tetrahydro-imidazo [1,5-a] pyridin derivatives as aldosterone synthase inhibitors |
ATE490241T1 (de) * | 2004-05-28 | 2010-12-15 | Novartis Ag | Heterocyclische verbindungen und deren verwendung als aldosteronsynthaseinhibitoren |
EP2261225A1 (en) * | 2004-05-28 | 2010-12-15 | Novartis AG | Heterocyclic compounds and their use as aldosterone synthase inhibitors |
TW200716105A (en) * | 2005-05-31 | 2007-05-01 | Speedel Experimenta Ag | Imidazole compounds |
GT200600381A (es) * | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
AR056888A1 (es) * | 2005-12-09 | 2007-10-31 | Speedel Experimenta Ag | Derivados de heterociclil imidazol |
EP1842543A1 (en) | 2006-04-05 | 2007-10-10 | Speedel Pharma AG | Pharmaceutical composition coprising an aldosterone synthase inhibitor and a mineralcorticoid receptor antagonist |
DE102008022221A1 (de) * | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
US8541404B2 (en) * | 2009-11-09 | 2013-09-24 | Elexopharm Gmbh | Inhibitors of the human aldosterone synthase CYP11B2 |
AR086665A1 (es) * | 2011-06-14 | 2014-01-15 | Lilly Co Eli | Inhibidor de aldosterona sintasa y composiciones farmaceuticas |
WO2018078049A1 (en) | 2016-10-27 | 2018-05-03 | Damian Pharma Ag | Aldosterone synthase inhibitor |
SG11202010906XA (en) | 2018-05-03 | 2020-12-30 | Damian Pharma Ag | R-fadrozole for use in the treatment of aldostonerism |
CN110507630A (zh) * | 2019-09-29 | 2019-11-29 | 陈汝霖 | 一种便携式腔道杀菌软胶囊 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4889861A (en) * | 1982-12-21 | 1989-12-26 | Ciba-Geigy Corp. | Substituted imidazo[1,5-a]pyridine derivatives and other substituted bicyclic derivatives and their use as aromatase inhibitors |
US4588732A (en) * | 1982-12-21 | 1986-05-13 | Ciba-Geigy Corporation | Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors |
US4728645A (en) * | 1982-12-21 | 1988-03-01 | Ciba-Geigy Corporation | Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors |
US4617307A (en) * | 1984-06-20 | 1986-10-14 | Ciba-Geigy Corporation | Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors |
-
1989
- 1989-09-26 US US07/412,369 patent/US5057521A/en not_active Expired - Fee Related
- 1989-10-17 EP EP89810787A patent/EP0366609B1/de not_active Expired - Lifetime
- 1989-10-17 DE DE58907570T patent/DE58907570D1/de not_active Expired - Fee Related
- 1989-10-17 AT AT8989810787T patent/ATE104852T1/de not_active IP Right Cessation
- 1989-10-22 IL IL9207889A patent/IL92078A/en not_active IP Right Cessation
- 1989-10-24 AU AU43722/89A patent/AU631814B2/en not_active Ceased
- 1989-10-24 CA CA002001301A patent/CA2001301A1/en not_active Abandoned
- 1989-10-25 KR KR1019890015327A patent/KR900005976A/ko not_active Application Discontinuation
- 1989-10-25 DK DK531089A patent/DK531089A/da not_active Application Discontinuation
- 1989-10-25 IE IE344189A patent/IE63481B1/en not_active IP Right Cessation
- 1989-10-25 ZA ZA898074A patent/ZA898074B/xx unknown
- 1989-10-26 JP JP1277326A patent/JPH02169518A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU631814B2 (en) | 1992-12-10 |
IL92078A0 (en) | 1990-07-12 |
EP0366609A2 (de) | 1990-05-02 |
EP0366609A3 (de) | 1992-01-02 |
EP0366609B1 (de) | 1994-04-27 |
DK531089A (da) | 1990-04-27 |
US5057521A (en) | 1991-10-15 |
DE58907570D1 (de) | 1994-06-01 |
DK531089D0 (da) | 1989-10-25 |
IE893441L (en) | 1990-04-26 |
JPH02169518A (ja) | 1990-06-29 |
CA2001301A1 (en) | 1990-04-26 |
ATE104852T1 (de) | 1994-05-15 |
IE63481B1 (en) | 1995-05-03 |
IL92078A (en) | 1995-08-31 |
KR900005976A (ko) | 1990-05-07 |
AU4372289A (en) | 1990-05-31 |
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