ZA881540B - Use of metformin in the preparation of medicines - Google Patents

Use of metformin in the preparation of medicines

Info

Publication number
ZA881540B
ZA881540B ZA881540A ZA881540A ZA881540B ZA 881540 B ZA881540 B ZA 881540B ZA 881540 A ZA881540 A ZA 881540A ZA 881540 A ZA881540 A ZA 881540A ZA 881540 B ZA881540 B ZA 881540B
Authority
ZA
South Africa
Prior art keywords
preparation
metformin
medicines
medicaments
neovascularisation
Prior art date
Application number
ZA881540A
Inventor
Wiernsperger Nicolas
Grand Marcel
Original Assignee
Lipha, Lyonnaise Industrielle Pharmaceutique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipha, Lyonnaise Industrielle Pharmaceutique filed Critical Lipha, Lyonnaise Industrielle Pharmaceutique
Publication of ZA881540B publication Critical patent/ZA881540B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to the use of metformin and its salts in the preparation of medicaments. This derivative is used in the preparation of medicaments manifesting anti-ischaemic and antianoxic properties. It is also employed in the preparation of medicaments intended for the treatment or regression of neovascularisation.
ZA881540A 1987-03-06 1988-03-03 Use of metformin in the preparation of medicines ZA881540B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8703028A FR2611500B1 (en) 1987-03-06 1987-03-06 USE OF BIGUANIDE DERIVATIVES IN THE PREPARATION OF MEDICINES

Publications (1)

Publication Number Publication Date
ZA881540B true ZA881540B (en) 1988-08-26

Family

ID=9348653

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA881540A ZA881540B (en) 1987-03-06 1988-03-03 Use of metformin in the preparation of medicines

Country Status (10)

Country Link
EP (1) EP0283369B1 (en)
JP (1) JPH0818978B2 (en)
AT (1) ATE98120T1 (en)
AU (1) AU610134B2 (en)
CA (1) CA1328606C (en)
DE (1) DE3886075T2 (en)
DK (1) DK169713B1 (en)
FR (1) FR2611500B1 (en)
IL (1) IL85627A (en)
ZA (1) ZA881540B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100919A (en) * 1984-03-19 1992-03-31 The Rockefeller University Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein
KR0170416B1 (en) * 1990-02-09 1999-02-18 로버트 에이. 아미테이지 Use of insulin sensitizing agents to treat hypertension
US5356913A (en) * 1990-02-09 1994-10-18 The Upjohn Company Use of insulin sensitizing agents to treat hypertension
DE4432757A1 (en) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmaceutical preparation containing metformin and process for its preparation
WO1996008262A1 (en) * 1994-09-15 1996-03-21 Pharmagenesis, Inc. Composition and method for immunotherapy
CA2312990C (en) * 1997-12-08 2008-04-29 Bristol-Myers Squibb Company Novel salts of metformin and method
US6099859A (en) 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
ES2224634T3 (en) * 1998-04-29 2005-03-01 Sumitomo Pharmaceuticals Company, Limited ORAL FORMULATION THAT INCLUDES BIGUANIDA AND AN ORGANIC ACID.
JP4606582B2 (en) * 1998-04-29 2011-01-05 大日本住友製薬株式会社 Biguanide drugs for internal use
SI0976395T1 (en) * 1998-07-30 2006-04-30 Merck Sante Sas Tablet for extended release of a drug in the stomach
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
FR2796551B1 (en) * 1999-07-23 2003-07-25 Lipha NOVEL METFORMIN SALTS, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
FR2796940B1 (en) * 1999-07-26 2005-04-08 Lipha NOVEL METFORMIN SALTS, PROCESS FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
FR2809310B1 (en) * 2000-05-26 2004-02-13 Centre Nat Rech Scient USE OF BIGUANIDE DERIVATIVES FOR MANUFACTURING A MEDICINAL PRODUCT HAVING A HEALING EFFECT
AU2001213150A1 (en) * 2000-08-03 2002-02-18 Olga Evgenievna Kolesova Composition of metformin with succinic acid or salts thereof and method for treating diabetes
US7959946B2 (en) 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en) 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
WO2007038979A1 (en) * 2005-09-22 2007-04-12 Swissco Development Ag Effervescent metformin composition and tablets and granules made therefrom
CN101652131A (en) 2007-01-29 2010-02-17 韩兀制药株式会社 N, N-dimethyl imidodicarbonimidic diamide acetate, its preparation method and comprise its pharmaceutical composition
GR1007299B (en) * 2010-03-24 2011-06-06 Uni - Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Αβεε, Original effervescent hydrochloric metformin composition in the form of tablets

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2448448A (en) * 1942-06-08 1948-08-31 Courtaulds Ltd Dyeing of textile fibers containing nitrogen

Also Published As

Publication number Publication date
EP0283369A2 (en) 1988-09-21
FR2611500B1 (en) 1990-05-04
DK116788A (en) 1988-09-07
DK169713B1 (en) 1995-01-23
IL85627A0 (en) 1988-08-31
EP0283369B1 (en) 1993-12-08
DE3886075D1 (en) 1994-01-20
IL85627A (en) 1993-01-14
AU1272788A (en) 1988-09-08
FR2611500A1 (en) 1988-09-09
JPS63230628A (en) 1988-09-27
JPH0818978B2 (en) 1996-02-28
DK116788D0 (en) 1988-03-04
ATE98120T1 (en) 1993-12-15
AU610134B2 (en) 1991-05-16
EP0283369A3 (en) 1989-11-29
CA1328606C (en) 1994-04-19
DE3886075T2 (en) 1994-04-14

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