IL85627A - Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts - Google Patents

Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts

Info

Publication number
IL85627A
IL85627A IL85627A IL8562788A IL85627A IL 85627 A IL85627 A IL 85627A IL 85627 A IL85627 A IL 85627A IL 8562788 A IL8562788 A IL 8562788A IL 85627 A IL85627 A IL 85627A
Authority
IL
Israel
Prior art keywords
metformin
salts
treatment
disorders
pharmaceutical compositions
Prior art date
Application number
IL85627A
Other versions
IL85627A0 (en
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipha filed Critical Lipha
Publication of IL85627A0 publication Critical patent/IL85627A0/en
Publication of IL85627A publication Critical patent/IL85627A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to the use of metformin and its salts in the preparation of medicaments. This derivative is used in the preparation of medicaments manifesting anti-ischaemic and antianoxic properties. It is also employed in the preparation of medicaments intended for the treatment or regression of neovascularisation.
IL85627A 1987-03-06 1988-03-03 Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts IL85627A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8703028A FR2611500B1 (en) 1987-03-06 1987-03-06 USE OF BIGUANIDE DERIVATIVES IN THE PREPARATION OF MEDICINES

Publications (2)

Publication Number Publication Date
IL85627A0 IL85627A0 (en) 1988-08-31
IL85627A true IL85627A (en) 1993-01-14

Family

ID=9348653

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85627A IL85627A (en) 1987-03-06 1988-03-03 Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts

Country Status (10)

Country Link
EP (1) EP0283369B1 (en)
JP (1) JPH0818978B2 (en)
AT (1) ATE98120T1 (en)
AU (1) AU610134B2 (en)
CA (1) CA1328606C (en)
DE (1) DE3886075T2 (en)
DK (1) DK169713B1 (en)
FR (1) FR2611500B1 (en)
IL (1) IL85627A (en)
ZA (1) ZA881540B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100919A (en) * 1984-03-19 1992-03-31 The Rockefeller University Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein
KR0170416B1 (en) * 1990-02-09 1999-02-18 로버트 에이. 아미테이지 Use of insulin sensitizing agents to treat hypertension
US5356913A (en) * 1990-02-09 1994-10-18 The Upjohn Company Use of insulin sensitizing agents to treat hypertension
DE4432757A1 (en) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmaceutical preparation containing metformin and process for its preparation
WO1996008262A1 (en) * 1994-09-15 1996-03-21 Pharmagenesis, Inc. Composition and method for immunotherapy
CA2312990C (en) * 1997-12-08 2008-04-29 Bristol-Myers Squibb Company Novel salts of metformin and method
US6099859A (en) 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
ES2224634T3 (en) * 1998-04-29 2005-03-01 Sumitomo Pharmaceuticals Company, Limited ORAL FORMULATION THAT INCLUDES BIGUANIDA AND AN ORGANIC ACID.
JP4606582B2 (en) * 1998-04-29 2011-01-05 大日本住友製薬株式会社 Biguanide drugs for internal use
SI0976395T1 (en) * 1998-07-30 2006-04-30 Merck Sante Sas Tablet for extended release of a drug in the stomach
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
FR2796551B1 (en) * 1999-07-23 2003-07-25 Lipha NOVEL METFORMIN SALTS, PROCESS FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
FR2796940B1 (en) * 1999-07-26 2005-04-08 Lipha NOVEL METFORMIN SALTS, PROCESS FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
FR2809310B1 (en) * 2000-05-26 2004-02-13 Centre Nat Rech Scient USE OF BIGUANIDE DERIVATIVES FOR MANUFACTURING A MEDICINAL PRODUCT HAVING A HEALING EFFECT
AU2001213150A1 (en) * 2000-08-03 2002-02-18 Olga Evgenievna Kolesova Composition of metformin with succinic acid or salts thereof and method for treating diabetes
US7959946B2 (en) 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en) 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
WO2007038979A1 (en) * 2005-09-22 2007-04-12 Swissco Development Ag Effervescent metformin composition and tablets and granules made therefrom
CN101652131A (en) 2007-01-29 2010-02-17 韩兀制药株式会社 N, N-dimethyl imidodicarbonimidic diamide acetate, its preparation method and comprise its pharmaceutical composition
GR1007299B (en) * 2010-03-24 2011-06-06 Uni - Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Αβεε, Original effervescent hydrochloric metformin composition in the form of tablets

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2448448A (en) * 1942-06-08 1948-08-31 Courtaulds Ltd Dyeing of textile fibers containing nitrogen

Also Published As

Publication number Publication date
EP0283369A2 (en) 1988-09-21
FR2611500B1 (en) 1990-05-04
DK116788A (en) 1988-09-07
DK169713B1 (en) 1995-01-23
IL85627A0 (en) 1988-08-31
EP0283369B1 (en) 1993-12-08
DE3886075D1 (en) 1994-01-20
AU1272788A (en) 1988-09-08
FR2611500A1 (en) 1988-09-09
JPS63230628A (en) 1988-09-27
JPH0818978B2 (en) 1996-02-28
DK116788D0 (en) 1988-03-04
ATE98120T1 (en) 1993-12-15
AU610134B2 (en) 1991-05-16
EP0283369A3 (en) 1989-11-29
ZA881540B (en) 1988-08-26
CA1328606C (en) 1994-04-19
DE3886075T2 (en) 1994-04-14

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Legal Events

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KB Patent renewed
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