ZA861837B - Benzo(c)-1,5-naphthyridines,a process and intermediates for their preparation and their use as medicaments - Google Patents

Benzo(c)-1,5-naphthyridines,a process and intermediates for their preparation and their use as medicaments

Info

Publication number: ZA861837B
Authority: ZA; South Africa
Prior art keywords: loweralkyl; intermediates; preparation; naphthyridines; medicaments
Prior art date: 1985-03-13

Application number

ZA861837A

Other languages

English (en)

Inventor

Lawrence L Martin

Linda L Setescak

Susan J Scott

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-13

Filing date

1986-03-12

Publication date

1987-06-24

1986-03-12 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1987-06-24 Publication of ZA861837B publication Critical patent/ZA861837B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Display Devices Of Pinball Game Machines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)

ZA861837A 1985-03-13 1986-03-12 Benzo(c)-1,5-naphthyridines,a process and intermediates for their preparation and their use as medicaments ZA861837B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/711,327 US4652567A (en)	1985-03-13	1985-03-13	Benzo(c)-1,5-naphthyridines useful for treating a patient having drug induced memory impairment in need of memory enhancement

Publications (1)

Publication Number	Publication Date
ZA861837B true ZA861837B (en)	1987-06-24

Family

ID=24857642

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA861837A ZA861837B (en)	1985-03-13	1986-03-12	Benzo(c)-1,5-naphthyridines,a process and intermediates for their preparation and their use as medicaments

Country Status (19)

Country	Link
US (1)	US4652567A (xx)
EP (1)	EP0197318B1 (xx)
JP (1)	JPS61212585A (xx)
KR (1)	KR860007255A (xx)
AT (1)	ATE52510T1 (xx)
AU (1)	AU590748B2 (xx)
CA (1)	CA1248108A (xx)
DE (1)	DE3671017D1 (xx)
DK (1)	DK114386A (xx)
ES (4)	ES8707528A1 (xx)
FI (1)	FI861001A (xx)
GR (1)	GR860681B (xx)
HU (2)	HU197007B (xx)
IL (1)	IL78117A0 (xx)
NO (1)	NO163489B (xx)
NZ (1)	NZ215439A (xx)
PH (1)	PH22279A (xx)
PT (1)	PT82187B (xx)
ZA (1)	ZA861837B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4766217A (en) *	1984-01-13	1988-08-23	Boehringer Ingelheim Kg	Preparation of 5,6-dihydro-pyrrolo[2,1-a]isoquinolines
WO1989002739A1 (en) *	1987-10-05	1989-04-06	Pfizer Inc.	4-aminopyridine derivatives
US5202440A (en) *	1987-10-05	1993-04-13	Pfizer Inc.	Certain 9-amino-2-(or 4)-oxa 1,2,3,4-tetrahydro- or 1,2,3,4,5,6,7,8-octahydro-acridines
US5994367A (en)	1997-03-07	1999-11-30	The University Of North Carolina At Chapel Hill	Method for treating tumors using 2-aryl-naphthyridin-4-ones

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2273533A1 (fr) *	1974-06-04	1976-01-02	Ferlux Sa	Nouveaux derives n-substitues d'acides pyrrolidones-2 carboxyliques-5
US4297358A (en) *	1979-01-16	1981-10-27	Ciba-Geigy Corporation	Novel 4,7-phenanthroline derivatives and pharmaceutical compositions containing them and their use
BE880455A (fr) *	1979-01-22	1980-06-06	Sandoz Sa	Compositions pharmaceutiques a base d'une benzo (c) (1,6) naphtyridine

1985
- 1985-03-13 US US06/711,327 patent/US4652567A/en not_active Expired - Lifetime
1986
- 1986-03-07 DE DE8686103085T patent/DE3671017D1/de not_active Expired - Fee Related
- 1986-03-07 EP EP86103085A patent/EP0197318B1/en not_active Expired - Lifetime
- 1986-03-07 AT AT86103085T patent/ATE52510T1/de not_active IP Right Cessation
- 1986-03-11 NZ NZ215439A patent/NZ215439A/xx unknown
- 1986-03-11 CA CA000503758A patent/CA1248108A/en not_active Expired
- 1986-03-11 HU HU861028A patent/HU197007B/hu not_active IP Right Cessation
- 1986-03-11 IL IL78117A patent/IL78117A0/xx unknown
- 1986-03-11 HU HU885579A patent/HU201756B/hu not_active IP Right Cessation
- 1986-03-11 PH PH33508A patent/PH22279A/en unknown
- 1986-03-11 FI FI861001A patent/FI861001A/fi not_active Application Discontinuation
- 1986-03-11 ES ES552874A patent/ES8707528A1/es not_active Expired
- 1986-03-12 NO NO860933A patent/NO163489B/no unknown
- 1986-03-12 GR GR860681A patent/GR860681B/el unknown
- 1986-03-12 DK DK114386A patent/DK114386A/da not_active Application Discontinuation
- 1986-03-12 ZA ZA861837A patent/ZA861837B/xx unknown
- 1986-03-12 JP JP61052750A patent/JPS61212585A/ja active Pending
- 1986-03-12 AU AU54658/86A patent/AU590748B2/en not_active Ceased
- 1986-03-13 KR KR1019860001804A patent/KR860007255A/ko not_active Application Discontinuation
- 1986-03-13 PT PT82187A patent/PT82187B/pt unknown
- 1986-11-17 ES ES557207A patent/ES8801269A1/es not_active Expired
- 1986-11-17 ES ES557208A patent/ES8800941A1/es not_active Expired
1987
- 1987-10-15 ES ES557768A patent/ES8801270A1/es not_active Expired

Also Published As

Publication number	Publication date
EP0197318A1 (en)	1986-10-15
HUT40658A (en)	1987-01-28
FI861001A0 (fi)	1986-03-11
DE3671017D1 (de)	1990-06-13
ES8801269A1 (es)	1988-01-01
DK114386A (da)	1986-09-14
US4652567A (en)	1987-03-24
PT82187A (en)	1986-04-01
AU590748B2 (en)	1989-11-16
ES8801270A1 (es)	1988-01-01
AU5465886A (en)	1986-09-18
HU197007B (en)	1989-02-28
KR860007255A (ko)	1986-10-10
HU201756B (en)	1990-12-28
DK114386D0 (da)	1986-03-12
ES557208A0 (es)	1987-12-01
PT82187B (en)	1988-01-07
IL78117A0 (en)	1986-07-31
GR860681B (en)	1986-07-14
NO860933L (no)	1986-09-15
ES557768A0 (es)	1988-01-01
EP0197318B1 (en)	1990-05-09
NZ215439A (en)	1990-03-27
PH22279A (en)	1988-07-14
NO163489B (no)	1990-02-26
CA1248108A (en)	1989-01-03
ES552874A0 (es)	1987-08-01
ATE52510T1 (de)	1990-05-15
ES557207A0 (es)	1988-01-01
ES8800941A1 (es)	1987-12-01
JPS61212585A (ja)	1986-09-20
ES8707528A1 (es)	1987-08-01
FI861001A (fi)	1986-09-14

Publication	Publication Date	Title
ZA876254B (en)	1988-04-27	Alpha-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones,a process for their preparation and their use as medicaments
ZA908800B (en)	1991-08-28	4-and 6-carbamates related to physostigmine,a process and intermediates for their preparation and their use as medicaments
IL101589A0 (en)	1992-12-30	1-(pyrido(3,4,b)-1,4-oxazinyl-4-yl)-1h-indoles,intermediates and a process for their preparation,and their use as medicaments
ZA878763B (en)	1988-05-19	Fused heterocyclic tetrahydroaminoquinolinols and related compounds,a process for their preparation and their use as medicaments
AU590748B2 (en)	1989-11-16	Benzo(C)-1,5-naphthyridines, a process and intermediates for their preparation and their use as medicaments
ZA898989B (en)	1990-08-29	Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine,a process for their preparation and their use as medicaments