ZA794618B - 4-hydroxy-2h-(1)benzothieno(2,3-e)-1,2-thiazine-3-carboxamide-1,1-dioxides and salts thereof, processes for their preparation, and pharmalceutical preparations thereof - Google Patents

4-hydroxy-2h-(1)benzothieno(2,3-e)-1,2-thiazine-3-carboxamide-1,1-dioxides and salts thereof, processes for their preparation, and pharmalceutical preparations thereof

Info

Publication number
ZA794618B
ZA794618B ZA00794618A ZA794618A ZA794618B ZA 794618 B ZA794618 B ZA 794618B ZA 00794618 A ZA00794618 A ZA 00794618A ZA 794618 A ZA794618 A ZA 794618A ZA 794618 B ZA794618 B ZA 794618B
Authority
ZA
South Africa
Prior art keywords
pharmalceutical
benzothieno
dioxides
thiazine
carboxamide
Prior art date
Application number
ZA00794618A
Other languages
English (en)
Inventor
R Zimmermann
G Trummlitz
W Engel
W Haarmann
E Seeger
G Engelhardt
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA794618B publication Critical patent/ZA794618B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA00794618A 1978-09-02 1979-08-31 4-hydroxy-2h-(1)benzothieno(2,3-e)-1,2-thiazine-3-carboxamide-1,1-dioxides and salts thereof, processes for their preparation, and pharmalceutical preparations thereof ZA794618B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782838377 DE2838377A1 (de) 1978-09-02 1978-09-02 Neue 4-hydroxy-2h eckige klammer auf 1 eckige klammer zu benzothieno eckige klammer auf 2,3-e eckige klammer zu -1,2- thiazin-3-carboxamid-1,1-dioxide sowie deren salze, deren verwendung und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA794618B true ZA794618B (en) 1981-05-27

Family

ID=6048562

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00794618A ZA794618B (en) 1978-09-02 1979-08-31 4-hydroxy-2h-(1)benzothieno(2,3-e)-1,2-thiazine-3-carboxamide-1,1-dioxides and salts thereof, processes for their preparation, and pharmalceutical preparations thereof

Country Status (14)

Country Link
US (1) US4259336A (el)
EP (1) EP0009142A1 (el)
JP (1) JPS5535086A (el)
AU (1) AU5046679A (el)
DE (1) DE2838377A1 (el)
DK (1) DK365879A (el)
ES (1) ES483711A1 (el)
FI (1) FI792721A (el)
GR (1) GR69999B (el)
IL (1) IL58155A0 (el)
NO (1) NO792828L (el)
PT (1) PT70134A (el)
YU (1) YU212279A (el)
ZA (1) ZA794618B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5811280A (en) * 1979-06-13 1980-12-18 F. Hoffmann-La Roche Ag Thiazine derivatives
GR80576B (en) * 1983-10-17 1984-11-29 Fujisawa Pharmaceutical Co Thiazine derivatives, process for preparation thereof and pharmaceutical composition comprising the same
US4683306A (en) * 1984-07-13 1987-07-28 Yuhan Corporation Co., Ltd. Process for the preparation of 3,4-dihydro-2-substituted-2H-1,2-thiazine-carboxylic acid 1,1-dioxide derivatives
JP2690742B2 (ja) * 1987-03-30 1997-12-17 第一製薬株式会社 複素環アミン誘導体
MX174093B (es) * 1987-06-10 1994-04-21 Pfizer 1,1-DIOXIDOS DE 3,4-DIHIDRO-2-ALQUIL-3-OXO-N-ARIL-2H[1] BENZOTIENO[3,2-e]-1,2-TIAZINO-4-CARBOXIAMIDA
EP1384723A1 (de) * 2002-07-26 2004-01-28 Boehringer Ingelheim Pharma GmbH & Co.KG Neue 4-Hydroxy-2H-thieno[2,3-e]-1,2-thiazin-3-carboxamid-1,1-dioxide, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL47877A (en) * 1974-08-26 1978-10-31 Sparamedica Ag Thienothiazine carboxamide derivatives,their manufacture and pharmaceutical compositions containing them
DE2539112C2 (de) * 1975-09-03 1983-12-15 Dr. Karl Thomae Gmbh, 7950 Biberach 4-Hydroxy-2H-naphtho[2,1-e]-1,2-thiazin-3-carboxamid-1,1-dioxide, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2452946A1 (de) * 1974-11-08 1976-05-13 Merck Patent Gmbh Pyrazolidinone und verfahren zu ihrer herstellung
SU623520A3 (ru) * 1976-09-07 1978-09-05 Ф.Гоффанн-Ля Рош И Ко Аг, (Фирма) Способ получени производных тиенотиазина
DE2704485A1 (de) * 1977-02-03 1978-08-10 Thomae Gmbh Dr K Neue 2,5-dihydro-1,2-thiazino eckige klammer auf 5,6-b eckige klammer zu indol-3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
AU518216B2 (en) * 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives

Also Published As

Publication number Publication date
DK365879A (da) 1980-03-03
PT70134A (de) 1979-09-01
AU5046679A (en) 1980-03-13
ES483711A1 (es) 1980-04-16
IL58155A0 (en) 1979-12-30
JPS5535086A (en) 1980-03-11
DE2838377A1 (de) 1980-03-20
FI792721A (fi) 1980-03-03
NO792828L (no) 1980-03-04
US4259336A (en) 1981-03-31
YU212279A (en) 1983-01-21
EP0009142A1 (de) 1980-04-02
GR69999B (el) 1982-07-23

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