ZA775651B - 4-n-acylfortimicin b derivatives and the chemical conversion of fortimicin b to fortimicin a - Google Patents

4-n-acylfortimicin b derivatives and the chemical conversion of fortimicin b to fortimicin a

Info

Publication number
ZA775651B
ZA775651B ZA00775651A ZA775651A ZA775651B ZA 775651 B ZA775651 B ZA 775651B ZA 00775651 A ZA00775651 A ZA 00775651A ZA 775651 A ZA775651 A ZA 775651A ZA 775651 B ZA775651 B ZA 775651B
Authority
ZA
South Africa
Prior art keywords
fortimicin
acylfortimicin
derivatives
chemical conversion
conversion
Prior art date
Application number
ZA00775651A
Other languages
English (en)
Inventor
Y Mori
J Tadanier
P Kurath
J Martin
M Sato
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA775651B publication Critical patent/ZA775651B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00775651A 1976-09-23 1977-09-21 4-n-acylfortimicin b derivatives and the chemical conversion of fortimicin b to fortimicin a ZA775651B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/725,829 US4091032A (en) 1976-09-23 1976-09-23 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

Publications (1)

Publication Number Publication Date
ZA775651B true ZA775651B (en) 1979-07-25

Family

ID=24916124

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA00775652A ZA775652B (en) 1976-09-23 1977-09-21 Fortimicin b derivatives and process for production thereof
ZA00775651A ZA775651B (en) 1976-09-23 1977-09-21 4-n-acylfortimicin b derivatives and the chemical conversion of fortimicin b to fortimicin a

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA00775652A ZA775652B (en) 1976-09-23 1977-09-21 Fortimicin b derivatives and process for production thereof

Country Status (17)

Country Link
US (2) US4091032A (xx)
JP (1) JPS5368752A (xx)
AR (1) AR224722A1 (xx)
AU (1) AU519064B2 (xx)
BE (1) BE859012A (xx)
CA (1) CA1114809A (xx)
DE (1) DE2742949C2 (xx)
DK (1) DK419877A (xx)
ES (2) ES462566A1 (xx)
FR (1) FR2365586A1 (xx)
GB (2) GB1591606A (xx)
GR (1) GR63596B (xx)
NO (1) NO773256L (xx)
NZ (1) NZ185239A (xx)
PH (1) PH16052A (xx)
SE (1) SE7710683L (xx)
ZA (2) ZA775652B (xx)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ185515A (en) * 1976-10-28 1980-08-26 Abbott Lab Fortimicin d and ke from culturing micromonospora olivoasterospora
JPS5466679A (en) * 1977-11-07 1979-05-29 Kyowa Hakko Kogyo Co Ltd Novel antibiotic substance fortimicin kf and fortimicin kg, and their preparation
US4214075A (en) * 1977-12-21 1980-07-22 Abbott Laboratories 6'-Epi-fortimicin A and B derivatives
JPS6041679B2 (ja) * 1978-03-03 1985-09-18 協和醗酵工業株式会社 新抗生物質ホ−テイマイシンｋｇ↓１，ｋｇ↓２およびｋｇ↓３ならびにそれらの製造法
US4234717A (en) * 1978-03-30 1980-11-18 American Cyanamid Company Antibacterial antibiotic BM782
US4208407A (en) * 1979-02-05 1980-06-17 Abbott Laboratories 5-Deoxyfortimicin A, 2,5-dideoxyfortimicin A and the corresponding 4-N-acyl and alkyl fortimicin B derivatives thereof and intermediates therefor
US4207415A (en) * 1979-02-05 1980-06-10 Abbott Laboratories Method of producing 2-deoxyfortimicin A
US4214080A (en) * 1979-03-29 1980-07-22 Abbott Laboratories Fortimicins AM and AP
US4213972A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'Di-N-fortimicins AH and AI
US4213971A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'-Di-N-fortimicin AD derivatives
JPS55130969A (en) * 1979-03-29 1980-10-11 Abbott Lab 11epiifortimicin a and derivative
US4219643A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicin AN
US4331804A (en) * 1979-03-29 1982-05-25 Abbott Laboratories 2-Epi-fortimicin A and derivatives
US4218442A (en) * 1979-03-29 1980-08-19 Abbott Laboratories 1-Epi-fortimicin A and derivatives
US4216210A (en) * 1979-03-29 1980-08-05 Abbott Laboratories Fortimicins AM and AP derivatives
US4226979A (en) * 1979-03-29 1980-10-07 Abbott Laboratories Fortimicin AK
US4293689A (en) * 1979-03-29 1981-10-06 Abbott Laboratories Method of producing 3-O-demethylfortimicin B from fortimicin AN
US4219642A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicin AO
US4214079A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'-Di-N-fortimicin AL derivatives
US4214078A (en) * 1979-03-29 1980-07-22 Abbott Laboratories Fortimicin AL
US4219644A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicins AH and AI
US4213974A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N,2'-N and 4,2'-Di-N-fortimicin AO derivatives
US4340727A (en) * 1979-09-26 1982-07-20 Abbott Laboratories 1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture
US4232147A (en) * 1979-09-26 1980-11-04 Abbott Laboratories 4-N-Acylfortimicin B-1,5-carbamates
US4230846A (en) * 1979-09-26 1980-10-28 Abbott Laboratories 1,5-Carbamates of fortimicin B and derivatives
US4431799A (en) * 1979-09-26 1984-02-14 Abbott Laboratories 6'-Modified fortimicin compounds
US4263429A (en) * 1979-09-26 1981-04-21 Abbott Laboratories 1,2,6-Tri-N-benzyloxycarbonylfortimicin B-4,5-carbamate and 1,2,6-tri-N-acetylfortimicin B-4,5-carbamate
US4275193A (en) * 1979-09-26 1981-06-23 Abbott Laboratories 4,5-Carbamates of fortimicin B
US4269970A (en) * 1979-09-26 1981-05-26 Abbott Laboratories 1,2-Carbamates of fortimicin B and derivatives
US4273925A (en) * 1979-09-26 1981-06-16 Abbott Laboratories 1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture
US4252972A (en) * 1979-09-26 1981-02-24 Abbott Laboratories Fortimicin B-1,2:4,5-bis-carbamates
US4382926A (en) * 1980-04-01 1983-05-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Formimidoyl A and B useful as semi-synthetic aminoglycosidic antibiotics
US4338308A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 4-N-β-Lysyl-2'-N-des-β-lysyl antibiotic AX-127B-1 and the pharmaceutically acceptable salts thereof
US4338307A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 2'-N-Des-β-lysyl antibiotic AX-127B-1 and 4-N-acyl and alkyl derivatives thereof
US4338309A (en) * 1980-11-10 1982-07-06 Abbott Laboratories 4',5'-Dihydro-antibiotic AX-127B-1; 2'-N-des-β-lysyl-4',5'-dihydro-antibiotic AX-127B-1; and 4-N-derivatives thereof
IE54288B1 (en) * 1982-03-05 1989-08-16 Fujisawa Pharmaceutical Co New 1,4-diaminocyclitol derivatives, processes for their preparation and pharmaceutical compositions containing them

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof
JPS5246311B2 (xx) * 1973-04-17 1977-11-24
JPS5145675B2 (xx) * 1973-07-23 1976-12-04
JPS50145588A (xx) * 1974-05-16 1975-11-21

Also Published As

Publication number Publication date
AR224722A1 (es) 1982-01-15
ES462566A1 (es) 1978-11-16
FR2365586B1 (xx) 1982-12-17
GB1591606A (en) 1981-06-24
DE2742949C2 (de) 1983-08-04
AU519064B2 (en) 1981-11-05
DK419877A (da) 1978-03-24
AU2902577A (en) 1979-03-29
ZA775652B (en) 1979-04-25
JPS5368752A (en) 1978-06-19
CA1114809A (en) 1981-12-22
GR63596B (en) 1979-11-26
ES472608A1 (es) 1979-02-16
GB1591320A (en) 1981-06-17
US4091032A (en) 1978-05-23
DE2742949A1 (de) 1978-03-30
NO773256L (no) 1978-03-29
SE7710683L (sv) 1978-03-24
NZ185239A (en) 1980-08-26
BE859012A (fr) 1978-03-23
FR2365586A1 (fr) 1978-04-21
PH16052A (en) 1983-06-02
US4155902A (en) 1979-05-22

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