ZA732637B - New quaternary salts of scopolamine and process for their production - Google Patents

New quaternary salts of scopolamine and process for their production

Info

Publication number
ZA732637B
ZA732637B ZA732637A ZA732637A ZA732637B ZA 732637 B ZA732637 B ZA 732637B ZA 732637 A ZA732637 A ZA 732637A ZA 732637 A ZA732637 A ZA 732637A ZA 732637 B ZA732637 B ZA 732637B
Authority
ZA
South Africa
Prior art keywords
scopolamine
production
quaternary salts
new quaternary
new
Prior art date
Application number
ZA732637A
Inventor
S Casadio
A Donetti
Original Assignee
Angeli Inst Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeli Inst Spa filed Critical Angeli Inst Spa
Publication of ZA732637B publication Critical patent/ZA732637B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA732637A 1972-04-18 1973-04-17 New quaternary salts of scopolamine and process for their production ZA732637B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1792072A GB1413484A (en) 1972-04-18 1972-04-18 Scopolamine derivatives

Publications (1)

Publication Number Publication Date
ZA732637B true ZA732637B (en) 1974-04-24

Family

ID=10103564

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA732637A ZA732637B (en) 1972-04-18 1973-04-17 New quaternary salts of scopolamine and process for their production

Country Status (28)

Country Link
US (1) US3853886A (en)
JP (1) JPS531808B2 (en)
AR (1) AR197500A1 (en)
AT (1) AT327406B (en)
AU (1) AU466971B2 (en)
BE (1) BE797976A (en)
CA (1) CA1010865A (en)
CH (1) CH576979A5 (en)
CS (1) CS172971B2 (en)
DD (1) DD106840A5 (en)
DE (1) DE2316728A1 (en)
DK (1) DK138801C (en)
ES (1) ES413535A1 (en)
FI (1) FI56685C (en)
FR (1) FR2187333B1 (en)
GB (1) GB1413484A (en)
HK (1) HK43278A (en)
HU (1) HU165697B (en)
IE (1) IE38748B1 (en)
IL (1) IL41959A (en)
IN (1) IN137569B (en)
NL (1) NL159667B (en)
NO (1) NO138176C (en)
PL (1) PL89160B1 (en)
SE (1) SE403112B (en)
SU (1) SU469250A3 (en)
YU (1) YU35025B (en)
ZA (1) ZA732637B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1164227B (en) * 1983-05-13 1987-04-08 Angeli Inst Spa PHARMACEUTICAL COMPOSITION SUITABLE FOR NASAL ADMINISTRATION OF QUATERNARY AMMONIUM SALTS AND ANTICOLINERGIC ACTIVITIES
IT1194343B (en) * 1983-07-26 1988-09-14 Valeas Spa ENDO-8,8-DIALKYL-8-AZONIABICICLO SALTS (3.2.1) OTTAN-6,7-ESSO-EPOSSI-3-ALCHILCARBOSSILATI, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE INGREDIENT
DE4140861C2 (en) * 1991-12-11 2003-12-11 Boehringer Ingelheim Kg Process for the production of quaternary tropic acid alkaloids
CN101307051B (en) * 2008-04-18 2011-08-10 重庆巨琪诺美制药有限公司 Process for synthesizing and detecting scopolamine derivates
CN103880837A (en) * 2014-03-27 2014-06-25 张家港威胜生物医药有限公司 Synthetic method of cimetropium bromide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670177A1 (en) * 1966-12-28 1970-11-12 Boehringer Sohn Ingelheim Process for the preparation of new N-substituted noratropinium salts

Also Published As

Publication number Publication date
NO138176B (en) 1978-04-10
IL41959A0 (en) 1973-06-29
US3853886A (en) 1974-12-10
HU165697B (en) 1974-10-28
AT327406B (en) 1976-01-26
FI56685B (en) 1979-11-30
FI56685C (en) 1980-03-10
NL159667B (en) 1979-03-15
DD106840A5 (en) 1974-07-05
FR2187333A1 (en) 1974-01-18
YU35025B (en) 1980-06-30
DK138801C (en) 1979-04-17
AU466971B2 (en) 1975-11-13
JPS4914615A (en) 1974-02-08
IE38748B1 (en) 1978-05-24
AU5440673A (en) 1974-10-17
IE38748L (en) 1973-10-18
CH576979A5 (en) 1976-06-30
ATA348173A (en) 1975-04-15
ES413535A1 (en) 1976-06-16
NO138176C (en) 1978-07-26
IN137569B (en) 1975-08-16
SE403112B (en) 1978-07-31
FR2187333B1 (en) 1976-10-22
PL89160B1 (en) 1976-10-30
IL41959A (en) 1976-01-30
JPS531808B2 (en) 1978-01-23
SU469250A3 (en) 1975-04-30
CS172971B2 (en) 1977-01-28
CA1010865A (en) 1977-05-24
YU95873A (en) 1979-12-31
DK138801B (en) 1978-10-30
DE2316728A1 (en) 1973-10-25
BE797976A (en) 1973-10-10
HK43278A (en) 1978-08-11
NL7304874A (en) 1973-10-22
GB1413484A (en) 1975-11-12
DE2316728C2 (en) 1988-09-08
AR197500A1 (en) 1974-04-15

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