ZA703208B - Alpha-(hydroxy and alkoxy substituted)phenyl-alpha-(2-piperidinyl)-methanols and processes for the preparation thereof - Google Patents

Alpha-(hydroxy and alkoxy substituted)phenyl-alpha-(2-piperidinyl)-methanols and processes for the preparation thereof

Info

Publication number
ZA703208B
ZA703208B ZA703208A ZA703208A ZA703208B ZA 703208 B ZA703208 B ZA 703208B ZA 703208 A ZA703208 A ZA 703208A ZA 703208 A ZA703208 A ZA 703208A ZA 703208 B ZA703208 B ZA 703208B
Authority
ZA
South Africa
Prior art keywords
alpha
methanols
piperidinyl
hydroxy
phenyl
Prior art date
Application number
ZA703208A
Inventor
G Sankey
K Whiting
Original Assignee
Minnesota 3M Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota 3M Lab Ltd filed Critical Minnesota 3M Lab Ltd
Publication of ZA703208B publication Critical patent/ZA703208B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA703208A 1969-05-20 1970-05-12 Alpha-(hydroxy and alkoxy substituted)phenyl-alpha-(2-piperidinyl)-methanols and processes for the preparation thereof ZA703208B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2563469 1969-05-20

Publications (1)

Publication Number Publication Date
ZA703208B true ZA703208B (en) 1971-01-27

Family

ID=10230843

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA703208A ZA703208B (en) 1969-05-20 1970-05-12 Alpha-(hydroxy and alkoxy substituted)phenyl-alpha-(2-piperidinyl)-methanols and processes for the preparation thereof

Country Status (12)

Country Link
JP (1) JPS4920787B1 (en)
BE (1) BE750590A (en)
CH (1) CH541557A (en)
DE (1) DE2024049C3 (en)
DK (1) DK124027B (en)
FR (1) FR2051549B1 (en)
GB (1) GB1316424A (en)
IL (1) IL34537A (en)
NL (1) NL169314C (en)
NO (1) NO133448C (en)
SE (1) SE374366B (en)
ZA (1) ZA703208B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA960676A (en) * 1970-05-21 1975-01-07 Smith Kline And French Canada Ltd. 3-sulfonamido-4-hydroxyphenyl-2-piperidinylcarbinols
US5169096A (en) * 1985-07-02 1992-12-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl-piperidine-methanol derivatives
US6004980A (en) * 1990-06-01 1999-12-21 Merrell Pharmaceuticals, Inc. (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
ATE114467T1 (en) * 1990-06-01 1994-12-15 Merrell Dow Pharma (+)-ALPHA-(2,3 DIMETHOXYPHENYL)-1-(2-(FLUOROPHENYL)ETHYL>-4-PIPERIDINEMETHANOL.
US6028083A (en) * 1997-07-25 2000-02-22 Hoechst Marion Roussel, Inc. Esters of (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE569836A (en) *

Also Published As

Publication number Publication date
FR2051549B1 (en) 1974-08-30
DE2024049A1 (en) 1970-12-17
NL169314B (en) 1982-02-01
CH541557A (en) 1973-09-15
FR2051549A1 (en) 1971-04-09
JPS4920787B1 (en) 1974-05-27
NL7007303A (en) 1970-11-24
BE750590A (en) 1970-11-19
NO133448B (en) 1976-01-26
SE374366B (en) 1975-03-03
NL169314C (en) 1982-07-01
IL34537A0 (en) 1970-07-19
GB1316424A (en) 1973-05-09
DE2024049B2 (en) 1977-11-24
IL34537A (en) 1973-03-30
DK124027B (en) 1972-09-04
NO133448C (en) 1976-05-05
DE2024049C3 (en) 1978-07-20

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