CH541557A - Process for the preparation of a- (hydroxy- and -alkoxy- substituted) -phenyl-a- (2-piperidinyl) -methanols - Google Patents

Process for the preparation of a- (hydroxy- and -alkoxy- substituted) -phenyl-a- (2-piperidinyl) -methanols

Info

Publication number
CH541557A
CH541557A CH740570A CH740570A CH541557A CH 541557 A CH541557 A CH 541557A CH 740570 A CH740570 A CH 740570A CH 740570 A CH740570 A CH 740570A CH 541557 A CH541557 A CH 541557A
Authority
CH
Switzerland
Prior art keywords
methanols
piperidinyl
alkoxy
hydroxy
phenyl
Prior art date
Application number
CH740570A
Other languages
German (de)
Inventor
Henry Dr Sankey George
Original Assignee
Minnesota 3M Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota 3M Lab Ltd filed Critical Minnesota 3M Lab Ltd
Publication of CH541557A publication Critical patent/CH541557A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CH740570A 1969-05-20 1970-05-19 Process for the preparation of a- (hydroxy- and -alkoxy- substituted) -phenyl-a- (2-piperidinyl) -methanols CH541557A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2563469 1969-05-20

Publications (1)

Publication Number Publication Date
CH541557A true CH541557A (en) 1973-09-15

Family

ID=10230843

Family Applications (1)

Application Number Title Priority Date Filing Date
CH740570A CH541557A (en) 1969-05-20 1970-05-19 Process for the preparation of a- (hydroxy- and -alkoxy- substituted) -phenyl-a- (2-piperidinyl) -methanols

Country Status (12)

Country Link
JP (1) JPS4920787B1 (en)
BE (1) BE750590A (en)
CH (1) CH541557A (en)
DE (1) DE2024049C3 (en)
DK (1) DK124027B (en)
FR (1) FR2051549B1 (en)
GB (1) GB1316424A (en)
IL (1) IL34537A (en)
NL (1) NL169314C (en)
NO (1) NO133448C (en)
SE (1) SE374366B (en)
ZA (1) ZA703208B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA960676A (en) * 1970-05-21 1975-01-07 Smith Kline And French Canada Ltd. 3-sulfonamido-4-hydroxyphenyl-2-piperidinylcarbinols
US5169096A (en) * 1985-07-02 1992-12-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl-piperidine-methanol derivatives
US6004980A (en) * 1990-06-01 1999-12-21 Merrell Pharmaceuticals, Inc. (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
HU213271B (en) * 1990-06-01 1997-04-28 Merrell Dow Pharma Process for producing (+)-alpha-(2,3-dimethoxi-phenyl)-1-[2-(4-fluoric-phenyl)-ethyl]-4-piperidine-methanole and pharmaceutical compositions containing the same
US6028083A (en) * 1997-07-25 2000-02-22 Hoechst Marion Roussel, Inc. Esters of (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE569836A (en) *

Also Published As

Publication number Publication date
NL7007303A (en) 1970-11-24
DE2024049B2 (en) 1977-11-24
NL169314C (en) 1982-07-01
BE750590A (en) 1970-11-19
ZA703208B (en) 1971-01-27
NO133448B (en) 1976-01-26
NO133448C (en) 1976-05-05
DE2024049C3 (en) 1978-07-20
NL169314B (en) 1982-02-01
JPS4920787B1 (en) 1974-05-27
GB1316424A (en) 1973-05-09
DE2024049A1 (en) 1970-12-17
SE374366B (en) 1975-03-03
IL34537A0 (en) 1970-07-19
IL34537A (en) 1973-03-30
DK124027B (en) 1972-09-04
FR2051549B1 (en) 1974-08-30
FR2051549A1 (en) 1971-04-09

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Legal Events

Date Code Title Description
PL Patent ceased