ZA200711080B - 1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus - Google Patents
1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virusInfo
- Publication number
- ZA200711080B ZA200711080B ZA200711080A ZA200711080A ZA200711080B ZA 200711080 B ZA200711080 B ZA 200711080B ZA 200711080 A ZA200711080 A ZA 200711080A ZA 200711080 A ZA200711080 A ZA 200711080A ZA 200711080 B ZA200711080 B ZA 200711080B
- Authority
- ZA
- South Africa
- Prior art keywords
- substituted
- 6alkyl
- benzimidazoilymethyl
- benzoimidazol
- dihydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05076438 | 2005-06-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200711080B true ZA200711080B (en) | 2009-03-25 |
Family
ID=35276402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200711080A ZA200711080B (en) | 2005-06-20 | 2007-12-19 | 1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus |
Country Status (12)
Country | Link |
---|---|
US (1) | US8034835B2 (de) |
EP (1) | EP1896473B1 (de) |
JP (1) | JP5078887B2 (de) |
CN (1) | CN101203517B (de) |
AT (1) | ATE529424T1 (de) |
AU (1) | AU2006260969B2 (de) |
BR (1) | BRPI0612628B8 (de) |
CA (1) | CA2612263C (de) |
MX (1) | MX2007016537A (de) |
RU (1) | RU2434000C2 (de) |
WO (1) | WO2006136561A1 (de) |
ZA (1) | ZA200711080B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8354434B2 (en) | 2006-01-30 | 2013-01-15 | Purdue Pharma L.P. | Cyclourea compounds as calcium channel blockers |
JP6162130B2 (ja) | 2011-10-14 | 2017-07-12 | アムビト ビオスシエンセス コルポラチオン | Iii型受容体チロシンキナーゼの調節因子としての複素環式化合物及びその使用 |
PE20160547A1 (es) | 2013-08-21 | 2016-06-19 | Alios Biopharma Inc | Compuestos antivirales |
MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
JO3637B1 (ar) | 2015-04-28 | 2020-08-27 | Janssen Sciences Ireland Uc | مركبات بيرازولو- وترايازولو- بيريميدين مضادة للفيروسات rsv |
CA3077309A1 (en) | 2017-09-29 | 2019-04-04 | Enanta Pharmaceuticals, Inc. | Combination pharmaceutical agents as rsv inhibitors |
TW201932470A (zh) | 2017-11-29 | 2019-08-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | 具有抗rsv活性之吡唑并嘧啶 |
JP7305658B2 (ja) | 2018-01-31 | 2023-07-10 | ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー | 抗rsv活性を有するシクロアルキル置換ピラゾロピリミジン |
AU2019260109B2 (en) | 2018-04-23 | 2023-07-13 | Janssen Sciences Ireland Unlimited Company | Heteroaromatic compounds having activity against RSV |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ20014574A3 (cs) | 1999-06-28 | 2002-05-15 | Janssen Pharmaceutica N. V. | Inhibitory replikace respiračně syncyciálního viru |
HUP0201789A3 (en) | 1999-06-28 | 2003-12-29 | Janssen Pharmaceutica Nv | Respiratory syncytial virus replication inhibitors |
HUP0201869A3 (en) | 1999-06-28 | 2003-12-29 | Janssen Pharmaceutica Nv | Respiratory syncytial virus replication inhibitors |
US6489338B2 (en) * | 2000-06-13 | 2002-12-03 | Bristol-Myers Squibb Company | Imidazopyridine and imidazopyrimidine antiviral agents |
AR046959A1 (es) * | 2003-12-18 | 2006-01-04 | Tibotec Pharm Ltd | Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio |
PL1697343T3 (pl) * | 2003-12-18 | 2009-12-31 | Tibotec Pharm Ltd | Aminobenzimidazole i benzimidazole jako inhibitory replikacji wirusa oddechowego |
-
2006
- 2006-06-20 CA CA2612263A patent/CA2612263C/en active Active
- 2006-06-20 US US11/993,109 patent/US8034835B2/en active Active
- 2006-06-20 CN CN2006800219722A patent/CN101203517B/zh active Active
- 2006-06-20 JP JP2008517487A patent/JP5078887B2/ja active Active
- 2006-06-20 RU RU2008102057/04A patent/RU2434000C2/ru active
- 2006-06-20 WO PCT/EP2006/063365 patent/WO2006136561A1/en active Application Filing
- 2006-06-20 BR BRPI0612628A patent/BRPI0612628B8/pt not_active IP Right Cessation
- 2006-06-20 AT AT06763808T patent/ATE529424T1/de not_active IP Right Cessation
- 2006-06-20 MX MX2007016537A patent/MX2007016537A/es active IP Right Grant
- 2006-06-20 AU AU2006260969A patent/AU2006260969B2/en not_active Ceased
- 2006-06-20 EP EP06763808A patent/EP1896473B1/de active Active
-
2007
- 2007-12-19 ZA ZA200711080A patent/ZA200711080B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0612628B8 (pt) | 2021-05-25 |
CN101203517B (zh) | 2011-07-06 |
MX2007016537A (es) | 2008-03-06 |
CA2612263C (en) | 2015-04-14 |
US20100183552A1 (en) | 2010-07-22 |
CA2612263A1 (en) | 2006-12-28 |
WO2006136561A1 (en) | 2006-12-28 |
US8034835B2 (en) | 2011-10-11 |
BRPI0612628A2 (pt) | 2012-01-03 |
AU2006260969A1 (en) | 2006-12-28 |
EP1896473A1 (de) | 2008-03-12 |
EP1896473B1 (de) | 2011-10-19 |
CN101203517A (zh) | 2008-06-18 |
JP2008546738A (ja) | 2008-12-25 |
RU2008102057A (ru) | 2009-07-27 |
BRPI0612628B1 (pt) | 2019-12-03 |
RU2434000C2 (ru) | 2011-11-20 |
JP5078887B2 (ja) | 2012-11-21 |
ATE529424T1 (de) | 2011-11-15 |
AU2006260969B2 (en) | 2011-11-17 |
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