ZA200711080B - 1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus - Google Patents

1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus

Info

Publication number
ZA200711080B
ZA200711080B ZA200711080A ZA200711080A ZA200711080B ZA 200711080 B ZA200711080 B ZA 200711080B ZA 200711080 A ZA200711080 A ZA 200711080A ZA 200711080 A ZA200711080 A ZA 200711080A ZA 200711080 B ZA200711080 B ZA 200711080B
Authority
ZA
South Africa
Prior art keywords
substituted
6alkyl
benzimidazoilymethyl
benzoimidazol
dihydro
Prior art date
Application number
ZA200711080A
Other languages
English (en)
Inventor
Bonfanti Jean-Francois
Fortin Jerome Michel Claude
Muller Phillippe
Doublet Frederic Marc Maurice
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of ZA200711080B publication Critical patent/ZA200711080B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200711080A 2005-06-20 2007-12-19 1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus ZA200711080B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05076438 2005-06-20

Publications (1)

Publication Number Publication Date
ZA200711080B true ZA200711080B (en) 2009-03-25

Family

ID=35276402

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200711080A ZA200711080B (en) 2005-06-20 2007-12-19 1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus

Country Status (12)

Country Link
US (1) US8034835B2 (de)
EP (1) EP1896473B1 (de)
JP (1) JP5078887B2 (de)
CN (1) CN101203517B (de)
AT (1) ATE529424T1 (de)
AU (1) AU2006260969B2 (de)
BR (1) BRPI0612628B8 (de)
CA (1) CA2612263C (de)
MX (1) MX2007016537A (de)
RU (1) RU2434000C2 (de)
WO (1) WO2006136561A1 (de)
ZA (1) ZA200711080B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8354434B2 (en) 2006-01-30 2013-01-15 Purdue Pharma L.P. Cyclourea compounds as calcium channel blockers
JP6162130B2 (ja) 2011-10-14 2017-07-12 アムビト ビオスシエンセス コルポラチオン Ｉｉｉ型受容体チロシンキナーゼの調節因子としての複素環式化合物及びその使用
PE20160547A1 (es) 2013-08-21 2016-06-19 Alios Biopharma Inc Compuestos antivirales
MA41614A (fr) 2015-02-25 2018-01-02 Alios Biopharma Inc Composés antiviraux
JO3637B1 (ar) 2015-04-28 2020-08-27 Janssen Sciences Ireland Uc مركبات بيرازولو- وترايازولو- بيريميدين مضادة للفيروسات rsv
CA3077309A1 (en) 2017-09-29 2019-04-04 Enanta Pharmaceuticals, Inc. Combination pharmaceutical agents as rsv inhibitors
TW201932470A (zh) 2017-11-29 2019-08-16 愛爾蘭商健生科學愛爾蘭無限公司 具有抗ｒｓｖ活性之吡唑并嘧啶
JP7305658B2 (ja) 2018-01-31 2023-07-10 ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー 抗ｒｓｖ活性を有するシクロアルキル置換ピラゾロピリミジン
AU2019260109B2 (en) 2018-04-23 2023-07-13 Janssen Sciences Ireland Unlimited Company Heteroaromatic compounds having activity against RSV

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20014574A3 (cs) 1999-06-28 2002-05-15 Janssen Pharmaceutica N. V. Inhibitory replikace respiračně syncyciálního viru
HUP0201789A3 (en) 1999-06-28 2003-12-29 Janssen Pharmaceutica Nv Respiratory syncytial virus replication inhibitors
HUP0201869A3 (en) 1999-06-28 2003-12-29 Janssen Pharmaceutica Nv Respiratory syncytial virus replication inhibitors
US6489338B2 (en) * 2000-06-13 2002-12-03 Bristol-Myers Squibb Company Imidazopyridine and imidazopyrimidine antiviral agents
AR046959A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
PL1697343T3 (pl) * 2003-12-18 2009-12-31 Tibotec Pharm Ltd Aminobenzimidazole i benzimidazole jako inhibitory replikacji wirusa oddechowego

Also Published As

Publication number Publication date
BRPI0612628B8 (pt) 2021-05-25
CN101203517B (zh) 2011-07-06
MX2007016537A (es) 2008-03-06
CA2612263C (en) 2015-04-14
US20100183552A1 (en) 2010-07-22
CA2612263A1 (en) 2006-12-28
WO2006136561A1 (en) 2006-12-28
US8034835B2 (en) 2011-10-11
BRPI0612628A2 (pt) 2012-01-03
AU2006260969A1 (en) 2006-12-28
EP1896473A1 (de) 2008-03-12
EP1896473B1 (de) 2011-10-19
CN101203517A (zh) 2008-06-18
JP2008546738A (ja) 2008-12-25
RU2008102057A (ru) 2009-07-27
BRPI0612628B1 (pt) 2019-12-03
RU2434000C2 (ru) 2011-11-20
JP5078887B2 (ja) 2012-11-21
ATE529424T1 (de) 2011-11-15
AU2006260969B2 (en) 2011-11-17

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