ZA200503534B - Implantation of encapsulated biological materials for treating diseases - Google Patents

Implantation of encapsulated biological materials for treating diseases Download PDF

Info

Publication number
ZA200503534B
ZA200503534B ZA200503534A ZA200503534A ZA200503534B ZA 200503534 B ZA200503534 B ZA 200503534B ZA 200503534 A ZA200503534 A ZA 200503534A ZA 200503534 A ZA200503534 A ZA 200503534A ZA 200503534 B ZA200503534 B ZA 200503534B
Authority
ZA
South Africa
Prior art keywords
composition
cells
encapsulated
peg
cell
Prior art date
Application number
ZA200503534A
Other languages
English (en)
Inventor
David Scharp
Paul Latta
Chengyun Yue
Jeffrey Hubbell
Xiaojie Yu
Original Assignee
Novocell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novocell Inc filed Critical Novocell Inc
Publication of ZA200503534B publication Critical patent/ZA200503534B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0677—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
ZA200503534A 2002-10-11 2005-05-04 Implantation of encapsulated biological materials for treating diseases ZA200503534B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41901502P 2002-10-11 2002-10-11

Publications (1)

Publication Number Publication Date
ZA200503534B true ZA200503534B (en) 2006-08-30

Family

ID=32094167

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200503534A ZA200503534B (en) 2002-10-11 2005-05-04 Implantation of encapsulated biological materials for treating diseases

Country Status (14)

Country Link
US (2) US7427415B2 (ja)
EP (1) EP1553893A4 (ja)
JP (1) JP2006503080A (ja)
KR (1) KR20050055760A (ja)
CN (1) CN1703175A (ja)
AU (1) AU2003285887B2 (ja)
BR (1) BR0315130A (ja)
CA (1) CA2501949A1 (ja)
MX (1) MXPA05003829A (ja)
NZ (1) NZ539713A (ja)
PL (1) PL376471A1 (ja)
RU (1) RU2340330C2 (ja)
WO (1) WO2004032881A2 (ja)
ZA (1) ZA200503534B (ja)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030040208A (ko) * 2000-05-08 2003-05-22 큐티엘 바이오시스템즈 엘엘씨 개선된 형광 폴리머-ｑｔｌ 바이오센싱 방법
US7440806B1 (en) * 2000-11-21 2008-10-21 Boston Scientific Neuromodulation Corp. Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion
US7493171B1 (en) * 2000-11-21 2009-02-17 Boston Scientific Neuromodulation Corp. Treatment of pathologic craving and aversion syndromes and eating disorders by electrical brain stimulation and/or drug infusion
US7678068B2 (en) 2002-12-02 2010-03-16 Gi Dynamics, Inc. Atraumatic delivery devices
US7695446B2 (en) 2002-12-02 2010-04-13 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US7025791B2 (en) 2002-12-02 2006-04-11 Gi Dynamics, Inc. Bariatric sleeve
AU2003298801B9 (en) 2002-12-02 2008-07-31 Gi Dynamics, Inc. Bariatric sleeve
US7608114B2 (en) 2002-12-02 2009-10-27 Gi Dynamics, Inc. Bariatric sleeve
US7820158B2 (en) * 2003-04-10 2010-10-26 Surmodics, Inc. Ligand-coupled initiator polymers and methods of use
US7585499B2 (en) * 2003-04-10 2009-09-08 Surmodics, Inc. Method for encapsulation of cellular material using a charged initiator polymer
US8202833B2 (en) * 2003-11-26 2012-06-19 Surmodics, Inc. Composition containing biocompatible polymerization accelerator and polymerizable material
US8057420B2 (en) 2003-12-09 2011-11-15 Gi Dynamics, Inc. Gastrointestinal implant with drawstring
WO2005060882A1 (en) 2003-12-09 2005-07-07 Gi Dynamics, Inc. Apparatus to be anchored within the gastrointestinal tract and anchoring method
WO2005072764A2 (en) * 2004-01-16 2005-08-11 Novocell, Inc. Fibrin-bound angiogenic factors to stimulate vascularization of transplant site of encapsulated cells
US7837643B2 (en) 2004-07-09 2010-11-23 Gi Dynamics, Inc. Methods and devices for placing a gastrointestinal sleeve
AU2005287010B2 (en) 2004-09-17 2010-04-15 Gi Dynamics, Inc. Gastrointestinal anchor
US7851189B2 (en) * 2005-03-07 2010-12-14 Boston Scientific Scimed, Inc. Microencapsulated compositions for endoluminal tissue engineering
US7976488B2 (en) 2005-06-08 2011-07-12 Gi Dynamics, Inc. Gastrointestinal anchor compliance
US20070122392A1 (en) * 2005-06-22 2007-05-31 Sharon Gerecht-Nir Propagation of undifferentiated embryonic stem cells in hyaluronic acid hydrogel
WO2007047539A2 (en) * 2005-10-14 2007-04-26 Medtronic, Inc. Localized delivery to the lymphatic system
US20070098695A1 (en) * 2005-10-31 2007-05-03 Deolden James Methods of islet separation during isolation
BR122015013776B1 (pt) 2005-11-09 2016-12-06 Klox Technologies Inc composição, método para branqueamento de dentes e kit
ATE487459T1 (de) * 2005-12-28 2010-11-15 Dentsply Int Inc Lichthärtbares knochenwachstumsmaterial zur behandlung von zahnknochendefekten
BRPI0600473A (pt) * 2006-02-06 2007-10-23 Phb Ind Sa implante polimérico e seu processo de preparação
EP2422796A3 (en) 2006-03-07 2013-03-13 Geeta Shroff Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation
CA2647549A1 (en) * 2006-03-31 2007-10-11 Csir Bulking of soft tissue
CA2649905C (en) 2006-04-20 2019-04-09 Dentatek Corporation Apparatus and methods for treating root canals of teeth
EP2052698A4 (en) 2006-08-08 2010-01-06 Fundacion Inasmet IMPLANTABLE OPTICAL SYSTEM, DEVELOPMENT METHOD AND APPLICATIONS
US7980854B2 (en) 2006-08-24 2011-07-19 Medical Dental Advanced Technologies Group, L.L.C. Dental and medical treatments and procedures
US20100266989A1 (en) 2006-11-09 2010-10-21 Klox Technologies Inc. Teeth whitening compositions and methods
US8801647B2 (en) 2007-02-22 2014-08-12 Gi Dynamics, Inc. Use of a gastrointestinal sleeve to treat bariatric surgery fistulas and leaks
EP3205355A1 (en) 2008-11-07 2017-08-16 KLOX Technologies, Inc. Combination of an oxidant and a photoactivator
CA2743641C (en) 2008-11-14 2024-03-26 Viacyte, Inc. Encapsulation of pancreatic cells derived from human pluripotent stem cells
CN102239248B (zh) * 2008-12-02 2013-10-30 皇家飞利浦电子股份有限公司 同轴封装的细胞悬浮液和微组织
IL196820A0 (en) 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
EP3904505A1 (en) 2009-04-22 2021-11-03 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
US9109245B2 (en) 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
US20100318371A1 (en) * 2009-06-11 2010-12-16 Halliburton Energy Services, Inc. Comprehensive hazard evaluation system and method for chemicals and products
LT2453922T (lt) 2009-07-17 2017-12-27 Klox Technologies Inc. Antibakterinė oralinė kompozicija
US8709400B2 (en) * 2009-07-27 2014-04-29 Washington University Inducement of organogenetic tolerance for pancreatic xenotransplant
PL2470228T3 (pl) 2009-08-28 2018-03-30 Sernova Corporation Sposoby i urządzenia do przeszczepiania komórek
US8858990B2 (en) * 2009-09-17 2014-10-14 The Ohio State University Capsule of thermogenic cells for treating a metabolic disease
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US9433557B2 (en) 2011-02-21 2016-09-06 Viacyte, Inc. Loading system for an encapsulation device
WO2012154627A2 (en) * 2011-05-06 2012-11-15 California Institute Of Technology Light delivery device and related compositions, methods and systems
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
US11116841B2 (en) 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
CA2884349C (en) 2012-09-14 2019-03-26 Valeant Pharmaceuticals International, Inc. Compositions and methods for teeth whitening
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
US8859286B2 (en) 2013-03-14 2014-10-14 Viacyte, Inc. In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells
CN105142570B (zh) 2013-04-24 2018-06-22 雀巢产品技术援助有限公司 包封装置
CN103305453A (zh) * 2013-05-23 2013-09-18 侯亚义 一种脐带间充质干细胞的微载体培养***
WO2014210220A2 (en) 2013-06-26 2014-12-31 Sonendo, Inc. Apparatus and methods for filling teeth and root canals
KR20210108505A (ko) 2013-07-03 2021-09-02 광동 클록스 바이오메디컬 그룹 씨오., 엘티디 상처를 치료하기 위한 발색단과 겔화제를 포함하는 생체광자성 조성물
AR099941A1 (es) 2014-04-01 2016-08-31 Klox Tech Inc Composiciones para relleno de tejido y métodos de uso
US11051900B2 (en) 2014-04-16 2021-07-06 Viacyte, Inc. Tools and instruments for use with implantable encapsulation devices
US11229607B2 (en) * 2014-06-30 2022-01-25 President And Fellows Of Harvard College Hydrogel compositions comprising encapsulated cells and methods of use thereof
AR101865A1 (es) * 2014-09-15 2017-01-18 Klox Tech Inc Matrices poliméricas emisivas
MX2017005673A (es) 2014-10-31 2017-08-02 Klox Tech Inc Materiales de tela y fibras fotoactivables.
CN104893825A (zh) * 2015-06-11 2015-09-09 东华大学 一种以聚脲为囊壁的香精微胶囊及其制备方法
US10918673B2 (en) 2015-08-28 2021-02-16 The Regents Of The University Of Michigan Immunoisolation device
EP3380078B1 (en) 2015-11-23 2021-01-13 Association for the Advancement of Tissue Engineering and Cell based Technologies & Therapies (A4TEC) - Associação Composition comprising polyeletrolyte complexes, methods and uses thereof
US20170252304A1 (en) * 2016-03-01 2017-09-07 Prodo Laboratories, Inc. Encapsulation Methods and Compositions
US10869840B2 (en) * 2016-03-09 2020-12-22 Incube Labs, Llc Methods and articles for delivering viable cells into solid tissue
US11655343B2 (en) 2016-03-24 2023-05-23 Takeda Pharmaceutical Company Limited Alginate hydrogel compositions
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
US20180035924A1 (en) * 2016-08-02 2018-02-08 Medtronic, Inc. Accelerometer signal change as a measure of patient functional status
US11052230B2 (en) * 2016-11-08 2021-07-06 W. L. Gore & Associates, Inc. Implantable encapsulation devices
BR112019009712A2 (pt) * 2016-11-15 2019-08-13 Giner Life Sciences Inc dispositivo de difusão gasosa percutânea adequado para uso com um implante subcutâneo
CN115463261A (zh) * 2016-12-13 2022-12-13 武田药品工业株式会社 生物表面的共形涂层
BR112019020611A2 (pt) * 2017-04-06 2020-04-22 Seraxis Inc células terapêuticas macroencapsuladas e processos de uso das mesmas
AU2019215096A1 (en) * 2018-02-02 2020-08-06 Wake Forest University Health Sciences Organoids related to immunotherapy and methods of preparing and using the same
CA3135365A1 (en) * 2019-03-29 2020-10-08 Nanyang Technological University Therapeutic hydrogel device
US11680141B2 (en) * 2019-05-02 2023-06-20 Sonendo, Inc. Hydrogel materials for obturation
CN110251731B (zh) * 2019-06-26 2021-09-03 山东百多安医疗器械股份有限公司 一种组织工程用胰岛细胞微囊及其制备方法
CN110201234B (zh) * 2019-06-26 2021-09-03 山东百多安医疗器械股份有限公司 一种组织工程用***细胞微囊及其制备方法
FR3108260B1 (fr) * 2020-03-17 2024-01-05 Neurobiomat Hydrogel hétérogène hybride, procédé de fabrication et utilisation comme implant de comblement non-dégradable in-situ
USD997355S1 (en) 2020-10-07 2023-08-29 Sonendo, Inc. Dental treatment instrument
US20240041755A1 (en) * 2020-12-22 2024-02-08 William Marsh Rice University Implantable constructs for modulating an immune response
CN114949369B (zh) * 2021-02-19 2023-09-05 清华大学 一种人工组织器官的封装装置及其制备方法和应用
WO2023164171A2 (en) 2022-02-25 2023-08-31 Viacyte, Inc. Multilayer implantable cell encapsulation devices and methods thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168053A (en) 1989-03-24 1992-12-01 Yale University Cleavage of targeted RNA by RNAase P
US5626863A (en) 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US20030087985A1 (en) 1990-10-15 2003-05-08 Hubbell Jeffrey A. Gels for encapsulation of biological materials
US5380536A (en) 1990-10-15 1995-01-10 The Board Of Regents, The University Of Texas System Biocompatible microcapsules
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5462990A (en) 1990-10-15 1995-10-31 Board Of Regents, The University Of Texas System Multifunctional organic polymers
US5232984A (en) 1990-10-15 1993-08-03 The Board Of The Regents The University Of Texas Biocompatible microcapsules
EP0610441A4 (en) 1991-10-29 1996-01-10 Clover Cons Ltd CROSSLINKABLE POLYSACCHARIDES, POLYCATIONS AND LIPIDS CAN BE USED TO ENCODE AND DISPENSE MEDICINAL PRODUCTS.
US5545423A (en) 1991-11-25 1996-08-13 Vivorx, Inc. Cytoprotective, biocompatible, retrievable macrocapsule containment systems for biologically active materials
EP0627911B1 (en) 1992-02-28 2000-10-25 Board Of Regents The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5573934A (en) 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
US5578442A (en) * 1992-03-23 1996-11-26 Vivorx, Inc. Graft copolymers of polycationic species and water-soluble polymers, and use therefor
US5334640A (en) 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
AU709527B2 (en) 1995-03-23 1999-09-02 Board Of Regents, The University Of Texas System Redox and photoinitiator systems for priming for improved adherence of gels to substrates
US6565842B1 (en) 1995-06-07 2003-05-20 American Bioscience, Inc. Crosslinkable polypeptide compositions
US5714360A (en) 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
DE69737909T3 (de) 1996-09-23 2014-07-24 Genzyme Corp. Polymerisierbare biologisch abbaubare polymere mit carbonat-oder dioxanonbindungen
US6368612B1 (en) 1997-12-12 2002-04-09 Biohybrid Technologies Llc Devices for cloaking transplanted cells
US6007833A (en) 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
US6410044B1 (en) 1998-03-19 2002-06-25 Surmodics, Inc. Crosslinkable macromers
US6326201B1 (en) 1999-02-10 2001-12-04 Curis, Inc. Pancreatic progenitor cells, methods and uses related thereto
US6495161B1 (en) * 1999-03-09 2002-12-17 Vivorx, Inc. Cytoprotective biocompatible containment systems for biologically active materials and methods of making same
US6278018B1 (en) 1999-12-14 2001-08-21 Surmodics, Inc. Surface coating agents
FR2814752A1 (fr) 2000-10-02 2002-04-05 Chru Lille Procede d'obtention in vitro de cellules insulino- secretrices de mammifere et leurs utilisations

Also Published As

Publication number Publication date
BR0315130A (pt) 2005-08-16
CN1703175A (zh) 2005-11-30
CA2501949A1 (en) 2004-04-22
RU2005113684A (ru) 2006-01-20
AU2003285887A1 (en) 2004-05-04
US7427415B2 (en) 2008-09-23
MXPA05003829A (es) 2005-10-05
PL376471A1 (en) 2005-12-27
US20040136971A1 (en) 2004-07-15
EP1553893A4 (en) 2010-09-22
KR20050055760A (ko) 2005-06-13
NZ539713A (en) 2008-07-31
WO2004032881A2 (en) 2004-04-22
EP1553893A2 (en) 2005-07-20
US20090004238A1 (en) 2009-01-01
WO2004032881A3 (en) 2004-09-02
JP2006503080A (ja) 2006-01-26
AU2003285887B2 (en) 2008-09-11
RU2340330C2 (ru) 2008-12-10

Similar Documents

Publication Publication Date Title
AU2003285887B2 (en) Implantation of encapsulated biological materials for treating diseases
Qi Transplantation of encapsulated pancreatic islets as a treatment for patients with type 1 diabetes mellitus
JP4435134B2 (ja) マクロカプセル化分泌腺細胞
Scharp et al. Encapsulated islets for diabetes therapy: history, current progress, and critical issues requiring solution
Kizilel et al. The bioartificial pancreas: progress and challenges
US20050180957A1 (en) Method of using fibrin-bound angiogenic factors to stimulate vascularization of transplant site of encapsulated cells
Mikos et al. Mini‐review: Islet transplantation to create a bioartificial pancreas
US20170252304A1 (en) Encapsulation Methods and Compositions
JPH10501523A (ja) 無被覆ゲル粒子を用いる方法
Zhu et al. Selection of implantation sites for transplantation of encapsulated pancreatic islets
Zhu et al. Treatment of diabetes with encapsulated pig islets: an update on current developments
JP2009533340A (ja) 細胞移植片のための複数膜の免疫隔離システム
Fukuda et al. The intraperitoneal space is more favorable than the subcutaneous one for transplanting alginate fiber containing iPS-derived islet-like cells
White et al. Engineering strategies to improve islet transplantation for type 1 diabetes therapy
Abbaszadeh et al. Emerging strategies to bypass transplant rejection via biomaterial-assisted immunoengineering: Insights from islets and beyond
Antosiak-Iwanska et al. Isolation, banking, encapsulation and transplantation of different types of Langerhans islets
USRE39542E1 (en) Preparation of agarose coated, solid agarose-collagen beads containing secretory cells
Lanza et al. Encapsulation technologies
US20200315976A1 (en) Encapsulation Methods and Compositions
NZ568319A (en) Implantation of encapsulated biological materials for treating diseases
Lanza et al. Encapsulated cell transplantation
Lee et al. Physical protection of pancreatic islets for transplantation
Kim et al. Use of Immunomodulatory Biomaterials in Diabetes Therapy
Wang et al. Bioartificial pancreas
Cotterell et al. Alternatives to immunosuppressive drugs in human islet transplantation