ZA200402557B - Glucagon-like peptides (GLP-1) and treatment of respiratory distress. - Google Patents
Glucagon-like peptides (GLP-1) and treatment of respiratory distress.Info
- Publication number
- ZA200402557B ZA200402557B ZA200402557A ZA200402557A ZA200402557B ZA 200402557 B ZA200402557 B ZA 200402557B ZA 200402557 A ZA200402557 A ZA 200402557A ZA 200402557 A ZA200402557 A ZA 200402557A ZA 200402557 B ZA200402557 B ZA 200402557B
- Authority
- ZA
- South Africa
- Prior art keywords
- glp
- glucagon
- peptides
- treatment
- respiratory distress
- Prior art date
Links
- DDYAPMZTJAYBOF-ZMYDTDHYSA-N (3S)-4-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-4-amino-1-[[(2S,3S)-1-[[(1S)-1-carboxyethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-4-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]amino]-5-oxopentanoyl]amino]-4-oxobutanoic acid Chemical class [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(O)=O DDYAPMZTJAYBOF-ZMYDTDHYSA-N 0.000 title 2
- 108010088406 Glucagon-Like Peptides Proteins 0.000 title 2
- 206010038687 Respiratory distress Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32633001P | 2001-10-01 | 2001-10-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200402557B true ZA200402557B (en) | 2005-05-09 |
Family
ID=23271764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200402557A ZA200402557B (en) | 2001-10-01 | 2004-03-31 | Glucagon-like peptides (GLP-1) and treatment of respiratory distress. |
Country Status (19)
Country | Link |
---|---|
US (2) | US20040235726A1 (xx) |
EP (1) | EP1443952A4 (xx) |
JP (1) | JP2005523877A (xx) |
KR (1) | KR20040040482A (xx) |
CN (1) | CN1561224A (xx) |
BR (1) | BR0212620A (xx) |
CA (1) | CA2462543A1 (xx) |
CZ (1) | CZ2004441A3 (xx) |
EA (1) | EA200400501A1 (xx) |
EC (1) | ECSP045044A (xx) |
HR (1) | HRP20040258A2 (xx) |
HU (1) | HUP0600437A2 (xx) |
IL (1) | IL160631A0 (xx) |
MX (1) | MXPA04002996A (xx) |
NO (1) | NO20041351L (xx) |
PL (1) | PL373846A1 (xx) |
SK (1) | SK1432004A3 (xx) |
WO (1) | WO2003028626A2 (xx) |
ZA (1) | ZA200402557B (xx) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003532691A (ja) | 2000-05-05 | 2003-11-05 | ノボ ノルディスク アクティーゼルスカブ | 重症疾患神経障害 |
US20030199445A1 (en) | 2002-02-07 | 2003-10-23 | Knudsen Lotte Bjerre | Use of GLP-1 compound for treatment of critically ill patients |
AU2003203146A1 (en) * | 2002-02-07 | 2003-09-02 | Novo Nordisk A/S | Use of glp-1 compound for treatment of critically ill patients |
WO2003072143A1 (en) * | 2002-02-27 | 2003-09-04 | Pharmain, Ltd. | Compositions for delivery of therapeutics and other materials, and methods of making and using the same |
US20050260259A1 (en) * | 2004-04-23 | 2005-11-24 | Bolotin Elijah M | Compositions for treatment with glucagon-like peptide, and methods of making and using the same |
US7635463B2 (en) | 2002-02-27 | 2009-12-22 | Pharmain Corporation | Compositions for delivery of therapeutics and other materials |
CA2551039C (en) | 2003-12-16 | 2013-01-29 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R | Analogues of glp-1 |
TWI364292B (en) | 2005-06-30 | 2012-05-21 | Ipsen Pharma Sas | Glp-1 pharmaceutical compositions |
AU2006330610B2 (en) | 2005-12-19 | 2012-08-16 | Pharmain Corporation | Hydrophobic core carrier compositions for delivery of therapeutic agents, methods of making and using the same |
MX2008013304A (es) | 2006-04-20 | 2008-10-27 | Amgen Inc | Compuestos de peptido 1 tipo glucagon. |
JP2010043001A (ja) * | 2006-11-09 | 2010-02-25 | Sanwa Kagaku Kenkyusho Co Ltd | Glp−1誘導体とその用途 |
US7960336B2 (en) | 2007-08-03 | 2011-06-14 | Pharmain Corporation | Composition for long-acting peptide analogs |
US8563527B2 (en) | 2007-08-20 | 2013-10-22 | Pharmain Corporation | Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same |
US20090176892A1 (en) | 2008-01-09 | 2009-07-09 | Pharmain Corporation | Soluble Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same |
EP2340049B1 (en) | 2008-09-12 | 2015-11-11 | Novo Nordisk A/S | Method of acylating a peptide or protein |
WO2010054326A2 (en) | 2008-11-07 | 2010-05-14 | The General Hospital Corporation | C-terminal fragments of glucagon-like peptide-1 (glp-1) |
EP2216042A1 (en) | 2009-02-09 | 2010-08-11 | Ipsen Pharma S.A.S. | GLP-1 analogues pharmaceutical compositions |
DE102009024229B3 (de) * | 2009-06-08 | 2010-10-14 | Salzsieder, Eckhard, Dipl.-Phys., Dr. rer.nat. | Indikationseinrichtung zur automatisierten Bestimmung des individuellen Inkretin-Sensitivitäts-Indexes eines Probanden |
JP2013530993A (ja) | 2010-07-02 | 2013-08-01 | アンジオケム インコーポレーテッド | 治療用コンジュゲートのための短く且つd−アミノ酸を含有するポリペプチドおよびその使用 |
US9040481B2 (en) | 2010-11-02 | 2015-05-26 | The General Hospital Corporation | Methods for treating steatotic disease |
EP2729157B1 (en) | 2011-07-06 | 2019-01-16 | The General Hospital Corporation | A pentapeptide derived from the c-terminus of glucagon-like peptide 1 (glp-1) for use in treatment |
ES2810153T3 (es) * | 2012-03-01 | 2021-03-08 | Novo Nordisk As | Profármacos de GLP-1 |
US20230218556A1 (en) * | 2020-05-01 | 2023-07-13 | Irazu Bio | Method for treating respiratory viral infections comprising administration of fatty acid compositions |
CN116847868A (zh) * | 2021-01-29 | 2023-10-03 | 韩美药品株式会社 | 用于预防或治疗肺部疾病的包括gip衍生物或其长效共轭物的药学组合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6006753A (en) * | 1996-08-30 | 1999-12-28 | Eli Lilly And Company | Use of GLP-1 or analogs to abolish catabolic changes after surgery |
US6277819B1 (en) * | 1996-08-30 | 2001-08-21 | Eli Lilly And Company | Use of GLP-1 or analogs in treatment of myocardial infarction |
MY155270A (en) * | 1998-09-24 | 2015-09-30 | Lilly Co Eli | Use of glp-1 or analogs in treatment of stroke |
US6271241B1 (en) * | 1999-04-02 | 2001-08-07 | Neurogen Corporation | Cycloalkyl and aryl fused aminoalkyl-imidazole derivatives: modulators and GLP-1 receptors |
-
2002
- 2002-09-19 SK SK143-2004A patent/SK1432004A3/sk not_active Application Discontinuation
- 2002-09-19 BR BR0212620-6A patent/BR0212620A/pt not_active IP Right Cessation
- 2002-09-19 EP EP02761559A patent/EP1443952A4/en not_active Withdrawn
- 2002-09-19 CZ CZ2004441A patent/CZ2004441A3/cs unknown
- 2002-09-19 IL IL16063102A patent/IL160631A0/xx unknown
- 2002-09-19 CN CNA028194535A patent/CN1561224A/zh active Pending
- 2002-09-19 EA EA200400501A patent/EA200400501A1/ru unknown
- 2002-09-19 JP JP2003531963A patent/JP2005523877A/ja active Pending
- 2002-09-19 WO PCT/US2002/028123 patent/WO2003028626A2/en active Application Filing
- 2002-09-19 US US10/488,670 patent/US20040235726A1/en not_active Abandoned
- 2002-09-19 CA CA002462543A patent/CA2462543A1/en not_active Abandoned
- 2002-09-19 KR KR10-2004-7004767A patent/KR20040040482A/ko not_active Application Discontinuation
- 2002-09-19 HU HU0600437A patent/HUP0600437A2/hu unknown
- 2002-09-19 MX MXPA04002996A patent/MXPA04002996A/es not_active Application Discontinuation
- 2002-09-19 PL PL02373846A patent/PL373846A1/xx not_active Application Discontinuation
-
2004
- 2004-03-17 HR HRP20040258 patent/HRP20040258A2/xx not_active Application Discontinuation
- 2004-03-31 NO NO20041351A patent/NO20041351L/no unknown
- 2004-03-31 ZA ZA200402557A patent/ZA200402557B/xx unknown
- 2004-04-01 EC EC2004005044A patent/ECSP045044A/es unknown
-
2007
- 2007-08-22 US US11/842,967 patent/US20080032932A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2003028626A2 (en) | 2003-04-10 |
CA2462543A1 (en) | 2003-04-10 |
PL373846A1 (en) | 2005-09-19 |
BR0212620A (pt) | 2005-09-20 |
CN1561224A (zh) | 2005-01-05 |
NO20041351D0 (no) | 2004-03-31 |
EP1443952A4 (en) | 2005-09-07 |
ECSP045044A (es) | 2004-04-28 |
EA200400501A1 (ru) | 2005-06-30 |
WO2003028626A3 (en) | 2003-10-09 |
MXPA04002996A (es) | 2004-07-15 |
US20080032932A1 (en) | 2008-02-07 |
CZ2004441A3 (cs) | 2004-11-10 |
KR20040040482A (ko) | 2004-05-12 |
HUP0600437A2 (en) | 2006-09-28 |
SK1432004A3 (sk) | 2005-03-04 |
US20040235726A1 (en) | 2004-11-25 |
EP1443952A2 (en) | 2004-08-11 |
HRP20040258A2 (en) | 2004-12-31 |
NO20041351L (no) | 2004-06-30 |
IL160631A0 (en) | 2004-07-25 |
JP2005523877A (ja) | 2005-08-11 |
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