ZA200110116B - Anaesthetic formulation comprising an NMDA-antagonist and an alpha-2 adrenergic agonist. - Google Patents
Anaesthetic formulation comprising an NMDA-antagonist and an alpha-2 adrenergic agonist. Download PDFInfo
- Publication number
- ZA200110116B ZA200110116B ZA200110116A ZA200110116A ZA200110116B ZA 200110116 B ZA200110116 B ZA 200110116B ZA 200110116 A ZA200110116 A ZA 200110116A ZA 200110116 A ZA200110116 A ZA 200110116A ZA 200110116 B ZA200110116 B ZA 200110116B
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- South Africa
- Prior art keywords
- alpha
- dexmedetomidine
- formulation
- anaesthetic
- tolerance
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
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GBGB9913677.2A GB9913677D0 (en) | 1999-06-11 | 1999-06-11 | Formulation |
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ZA200110116B true ZA200110116B (en) | 2003-07-23 |
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ZA200110116A ZA200110116B (en) | 1999-06-11 | 2001-12-10 | Anaesthetic formulation comprising an NMDA-antagonist and an alpha-2 adrenergic agonist. |
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US (1) | US6562855B1 (de) |
EP (1) | EP1187635B1 (de) |
JP (1) | JP2003529541A (de) |
AT (1) | ATE259658T1 (de) |
AU (1) | AU778671B2 (de) |
CA (1) | CA2376916C (de) |
DE (1) | DE60008374T2 (de) |
DK (1) | DK1187635T3 (de) |
ES (1) | ES2215678T3 (de) |
GB (2) | GB9913677D0 (de) |
PT (1) | PT1187635E (de) |
RU (1) | RU2244558C2 (de) |
WO (1) | WO2000076545A1 (de) |
ZA (1) | ZA200110116B (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2812545B1 (fr) * | 2000-08-03 | 2003-03-28 | Air Liquide Sante Int | Aerosol medicamenteux inhalable dans le traitement ou la prevention de la douceur |
GB0209998D0 (en) * | 2002-05-01 | 2002-06-12 | Protexeon Ltd | Use |
WO2003105871A1 (de) | 2002-06-12 | 2003-12-24 | Messer Griesheim Gmbh | Cerebrale protektion mit einem xenonhaltigen gas |
CN1665542A (zh) * | 2002-07-05 | 2005-09-07 | 梅瑟·格里斯海姆有限公司 | 含氙的佐剂 |
WO2004052337A2 (de) * | 2002-12-06 | 2004-06-24 | Michael Georgieff | Nasale pharmazeutische präparation enthaltend eine lipophile flüssige oder gasförmige wirksubstanz |
EP1675597A2 (de) * | 2003-10-21 | 2006-07-05 | Aga Ab | Verwendung von xenon zur prävention von programmiertem zelltod |
US7795263B2 (en) * | 2008-07-08 | 2010-09-14 | Wildlife Laboratories, Inc. | Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals |
US20100022574A1 (en) * | 2008-07-28 | 2010-01-28 | EndogenX, Inc. | Methods to Treat Pain Using an Alpha-2 Adrenergic Agonist and an Endothelin Antagonist |
US8952011B2 (en) | 2008-08-01 | 2015-02-10 | Eye Therapies Llc | Compositions and methods for the treatment of nasal conditions |
US20110244058A1 (en) * | 2008-08-01 | 2011-10-06 | Gerald Horn | Compositions and methods for treatment of pulmonary diseases and conditions |
US20100203165A1 (en) | 2008-08-01 | 2010-08-12 | Gerald Horn | Compositions and methods for treatment of disorders or conditions of the eye |
US8283350B2 (en) | 2008-08-01 | 2012-10-09 | Alpha Synergy Development, Inc. | Compositions and methods for reducing capillary permeability |
KR101859486B1 (ko) * | 2009-05-15 | 2018-06-28 | 레크로파마, 인코포레이티드 | 설하용 덱스메데토미딘 조성물과 그의 사용 방법 |
US8987270B2 (en) | 2009-07-27 | 2015-03-24 | Eye Therapies Llc | Formulations of selective alpha-2 agonists and methods of use thereof |
US20110152271A1 (en) * | 2009-12-17 | 2011-06-23 | Gerald Horn | Compositions and methods for ophthalmic delivery of nasal decongestants |
JP2013516482A (ja) * | 2010-01-08 | 2013-05-13 | レクロ・ファーマ,インコーポレーテッド | 局所経皮用デクスメデトミジン組成物およびそれらの使用方法 |
CN103068394A (zh) * | 2010-04-15 | 2013-04-24 | 皇家学习促进学会/麦吉尔大学 | 对于疼痛的局部治疗 |
US8445526B2 (en) | 2011-02-03 | 2013-05-21 | Glaucoma & Nasal Therapies Llc | Compositions and methods for treatment of glaucoma |
US20130096170A1 (en) | 2011-10-14 | 2013-04-18 | Hospira, Inc. | Methods of treating pediatric patients using dexmedetomidine |
AU2012352528B9 (en) | 2011-12-11 | 2017-11-02 | Baudax Bio, Inc. | Intranasal dexmedetomidine compositions and methods of use thereof |
CN103565745A (zh) | 2012-08-10 | 2014-02-12 | 德克萨斯州大学***董事会 | 用于治疗中风的神经保护性脂质体组合物和方法 |
JP6625966B2 (ja) | 2013-03-15 | 2019-12-25 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 希ガスが豊富な液体ならびにその調製及び使用の方法 |
US8999938B2 (en) | 2013-06-21 | 2015-04-07 | Gnt Llc | Ophthalmic lipophilic drug delivery vehicle formulations |
TWI709417B (zh) | 2013-10-07 | 2020-11-11 | 美商帝國製藥美國股份有限公司 | 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物 |
US10772871B2 (en) | 2013-10-07 | 2020-09-15 | Teikoku Pharma Usa, Inc. | Dexmedetomidine transdermal delivery devices and methods for using the same |
EP3054930B1 (de) | 2013-10-07 | 2020-12-02 | Teikoku Pharma USA, Inc. | Verfahren und zusammensetzungen zur transdermalen verabreichung einer nicht-sedierenden menge an descmedetomidin |
RU2557882C1 (ru) * | 2014-07-08 | 2015-07-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Астраханская государственная медицинская академия" Министерства здравоохранения Российской Федерации (ГБОУ ВПО АГМА Минздрава России) | Способ проведения премедикации при плановом хирургическом лечении |
WO2017139382A1 (en) * | 2016-02-08 | 2017-08-17 | The Texas A&M University System | Combination of adjuvant drugs esketamine and brimonidine for medical treatments |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
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US4859685A (en) * | 1986-08-13 | 1989-08-22 | Boc, Inc. | Anesthetic composition and method of using the same |
US5605911A (en) * | 1995-01-31 | 1997-02-25 | Washington University | Use of alpha-2 adrenergic drugs to prevent adverse effects of NMDA receptor hypofunction (NRH) |
JP2000500020A (ja) | 1995-11-13 | 2000-01-11 | コミサリア・ア・レネルジー・アトミーク | 正十二面体様アデノウイルス・タンパク質複合体、それを含む組成物、及びその使用方法 |
DE19709704C2 (de) | 1997-03-10 | 1999-11-04 | Michael Georgieff | Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie |
FR2787713A1 (fr) | 1998-12-23 | 2000-06-30 | Johan Huysman | Composition en tant que medicament et utilisation d'une telle composition pour l'obtention d'un medicament destine a l'anesthesie, notamment medicament analgesique |
DE19910986C2 (de) | 1999-03-11 | 2001-06-07 | Aga Ab | Verwendung von Xenon bei der Behandlung von Neurointoxikationen |
GB9917822D0 (en) * | 1999-07-29 | 1999-09-29 | Imperial College | Nmda antagonist |
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- 2000-06-09 DK DK00940519T patent/DK1187635T3/da active
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- 2000-06-09 JP JP2001502877A patent/JP2003529541A/ja not_active Ceased
- 2000-06-09 GB GB0014165A patent/GB2352633B/en not_active Expired - Fee Related
- 2000-06-09 DE DE60008374T patent/DE60008374T2/de not_active Expired - Lifetime
- 2000-06-09 AT AT00940519T patent/ATE259658T1/de active
- 2000-06-09 CA CA2376916A patent/CA2376916C/en not_active Expired - Lifetime
- 2000-06-09 WO PCT/GB2000/002271 patent/WO2000076545A1/en active IP Right Grant
- 2000-06-09 RU RU2002100254/15A patent/RU2244558C2/ru not_active IP Right Cessation
- 2000-06-09 EP EP00940519A patent/EP1187635B1/de not_active Expired - Lifetime
- 2000-06-09 PT PT00940519T patent/PT1187635E/pt unknown
- 2000-06-09 AU AU55444/00A patent/AU778671B2/en not_active Ceased
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Also Published As
Publication number | Publication date |
---|---|
AU778671B2 (en) | 2004-12-16 |
US6562855B1 (en) | 2003-05-13 |
EP1187635B1 (de) | 2004-02-18 |
RU2244558C2 (ru) | 2005-01-20 |
ES2215678T3 (es) | 2004-10-16 |
GB2352633A (en) | 2001-02-07 |
WO2000076545A1 (en) | 2000-12-21 |
GB0014165D0 (en) | 2000-08-02 |
GB9913677D0 (en) | 1999-08-11 |
CA2376916C (en) | 2010-09-21 |
GB2352633B (en) | 2002-04-17 |
ATE259658T1 (de) | 2004-03-15 |
DE60008374T2 (de) | 2004-12-09 |
PT1187635E (pt) | 2004-07-30 |
DE60008374D1 (de) | 2004-03-25 |
AU5544400A (en) | 2001-01-02 |
CA2376916A1 (en) | 2000-12-21 |
JP2003529541A (ja) | 2003-10-07 |
EP1187635A1 (de) | 2002-03-20 |
DK1187635T3 (da) | 2004-06-21 |
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