ZA200110116B - Anaesthetic formulation comprising an NMDA-antagonist and an alpha-2 adrenergic agonist. - Google Patents

Anaesthetic formulation comprising an NMDA-antagonist and an alpha-2 adrenergic agonist. Download PDF

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Publication number
ZA200110116B
ZA200110116B ZA200110116A ZA200110116A ZA200110116B ZA 200110116 B ZA200110116 B ZA 200110116B ZA 200110116 A ZA200110116 A ZA 200110116A ZA 200110116 A ZA200110116 A ZA 200110116A ZA 200110116 B ZA200110116 B ZA 200110116B
Authority
ZA
South Africa
Prior art keywords
alpha
dexmedetomidine
formulation
anaesthetic
tolerance
Prior art date
Application number
ZA200110116A
Other languages
English (en)
Inventor
Nicholas Peter Franks
Mervyn Maze
Original Assignee
Protexeon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10855216&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200110116(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Protexeon Ltd filed Critical Protexeon Ltd
Publication of ZA200110116B publication Critical patent/ZA200110116B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
ZA200110116A 1999-06-11 2001-12-10 Anaesthetic formulation comprising an NMDA-antagonist and an alpha-2 adrenergic agonist. ZA200110116B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9913677.2A GB9913677D0 (en) 1999-06-11 1999-06-11 Formulation

Publications (1)

Publication Number Publication Date
ZA200110116B true ZA200110116B (en) 2003-07-23

Family

ID=10855216

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200110116A ZA200110116B (en) 1999-06-11 2001-12-10 Anaesthetic formulation comprising an NMDA-antagonist and an alpha-2 adrenergic agonist.

Country Status (14)

Country Link
US (1) US6562855B1 (de)
EP (1) EP1187635B1 (de)
JP (1) JP2003529541A (de)
AT (1) ATE259658T1 (de)
AU (1) AU778671B2 (de)
CA (1) CA2376916C (de)
DE (1) DE60008374T2 (de)
DK (1) DK1187635T3 (de)
ES (1) ES2215678T3 (de)
GB (2) GB9913677D0 (de)
PT (1) PT1187635E (de)
RU (1) RU2244558C2 (de)
WO (1) WO2000076545A1 (de)
ZA (1) ZA200110116B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812545B1 (fr) * 2000-08-03 2003-03-28 Air Liquide Sante Int Aerosol medicamenteux inhalable dans le traitement ou la prevention de la douceur
GB0209998D0 (en) * 2002-05-01 2002-06-12 Protexeon Ltd Use
WO2003105871A1 (de) 2002-06-12 2003-12-24 Messer Griesheim Gmbh Cerebrale protektion mit einem xenonhaltigen gas
CN1665542A (zh) * 2002-07-05 2005-09-07 梅瑟·格里斯海姆有限公司 含氙的佐剂
WO2004052337A2 (de) * 2002-12-06 2004-06-24 Michael Georgieff Nasale pharmazeutische präparation enthaltend eine lipophile flüssige oder gasförmige wirksubstanz
EP1675597A2 (de) * 2003-10-21 2006-07-05 Aga Ab Verwendung von xenon zur prävention von programmiertem zelltod
US7795263B2 (en) * 2008-07-08 2010-09-14 Wildlife Laboratories, Inc. Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
US20100022574A1 (en) * 2008-07-28 2010-01-28 EndogenX, Inc. Methods to Treat Pain Using an Alpha-2 Adrenergic Agonist and an Endothelin Antagonist
US8952011B2 (en) 2008-08-01 2015-02-10 Eye Therapies Llc Compositions and methods for the treatment of nasal conditions
US20110244058A1 (en) * 2008-08-01 2011-10-06 Gerald Horn Compositions and methods for treatment of pulmonary diseases and conditions
US20100203165A1 (en) 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of disorders or conditions of the eye
US8283350B2 (en) 2008-08-01 2012-10-09 Alpha Synergy Development, Inc. Compositions and methods for reducing capillary permeability
KR101859486B1 (ko) * 2009-05-15 2018-06-28 레크로파마, 인코포레이티드 설하용 덱스메데토미딘 조성물과 그의 사용 방법
US8987270B2 (en) 2009-07-27 2015-03-24 Eye Therapies Llc Formulations of selective alpha-2 agonists and methods of use thereof
US20110152271A1 (en) * 2009-12-17 2011-06-23 Gerald Horn Compositions and methods for ophthalmic delivery of nasal decongestants
JP2013516482A (ja) * 2010-01-08 2013-05-13 レクロ・ファーマ,インコーポレーテッド 局所経皮用デクスメデトミジン組成物およびそれらの使用方法
CN103068394A (zh) * 2010-04-15 2013-04-24 皇家学习促进学会/麦吉尔大学 对于疼痛的局部治疗
US8445526B2 (en) 2011-02-03 2013-05-21 Glaucoma & Nasal Therapies Llc Compositions and methods for treatment of glaucoma
US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
AU2012352528B9 (en) 2011-12-11 2017-11-02 Baudax Bio, Inc. Intranasal dexmedetomidine compositions and methods of use thereof
CN103565745A (zh) 2012-08-10 2014-02-12 德克萨斯州大学***董事会 用于治疗中风的神经保护性脂质体组合物和方法
JP6625966B2 (ja) 2013-03-15 2019-12-25 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 希ガスが豊富な液体ならびにその調製及び使用の方法
US8999938B2 (en) 2013-06-21 2015-04-07 Gnt Llc Ophthalmic lipophilic drug delivery vehicle formulations
TWI709417B (zh) 2013-10-07 2020-11-11 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
US10772871B2 (en) 2013-10-07 2020-09-15 Teikoku Pharma Usa, Inc. Dexmedetomidine transdermal delivery devices and methods for using the same
EP3054930B1 (de) 2013-10-07 2020-12-02 Teikoku Pharma USA, Inc. Verfahren und zusammensetzungen zur transdermalen verabreichung einer nicht-sedierenden menge an descmedetomidin
RU2557882C1 (ru) * 2014-07-08 2015-07-27 Государственное бюджетное образовательное учреждение высшего профессионального образования "Астраханская государственная медицинская академия" Министерства здравоохранения Российской Федерации (ГБОУ ВПО АГМА Минздрава России) Способ проведения премедикации при плановом хирургическом лечении
WO2017139382A1 (en) * 2016-02-08 2017-08-17 The Texas A&M University System Combination of adjuvant drugs esketamine and brimonidine for medical treatments

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859685A (en) * 1986-08-13 1989-08-22 Boc, Inc. Anesthetic composition and method of using the same
US5605911A (en) * 1995-01-31 1997-02-25 Washington University Use of alpha-2 adrenergic drugs to prevent adverse effects of NMDA receptor hypofunction (NRH)
JP2000500020A (ja) 1995-11-13 2000-01-11 コミサリア・ア・レネルジー・アトミーク 正十二面体様アデノウイルス・タンパク質複合体、それを含む組成物、及びその使用方法
DE19709704C2 (de) 1997-03-10 1999-11-04 Michael Georgieff Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie
FR2787713A1 (fr) 1998-12-23 2000-06-30 Johan Huysman Composition en tant que medicament et utilisation d'une telle composition pour l'obtention d'un medicament destine a l'anesthesie, notamment medicament analgesique
DE19910986C2 (de) 1999-03-11 2001-06-07 Aga Ab Verwendung von Xenon bei der Behandlung von Neurointoxikationen
GB9917822D0 (en) * 1999-07-29 1999-09-29 Imperial College Nmda antagonist

Also Published As

Publication number Publication date
AU778671B2 (en) 2004-12-16
US6562855B1 (en) 2003-05-13
EP1187635B1 (de) 2004-02-18
RU2244558C2 (ru) 2005-01-20
ES2215678T3 (es) 2004-10-16
GB2352633A (en) 2001-02-07
WO2000076545A1 (en) 2000-12-21
GB0014165D0 (en) 2000-08-02
GB9913677D0 (en) 1999-08-11
CA2376916C (en) 2010-09-21
GB2352633B (en) 2002-04-17
ATE259658T1 (de) 2004-03-15
DE60008374T2 (de) 2004-12-09
PT1187635E (pt) 2004-07-30
DE60008374D1 (de) 2004-03-25
AU5544400A (en) 2001-01-02
CA2376916A1 (en) 2000-12-21
JP2003529541A (ja) 2003-10-07
EP1187635A1 (de) 2002-03-20
DK1187635T3 (da) 2004-06-21

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