YU7604A - Polimorf soli derivata piridazinona za tretman aritmije - Google Patents
Polimorf soli derivata piridazinona za tretman aritmijeInfo
- Publication number
- YU7604A YU7604A YU7604A YUP7604A YU7604A YU 7604 A YU7604 A YU 7604A YU 7604 A YU7604 A YU 7604A YU P7604 A YUP7604 A YU P7604A YU 7604 A YU7604 A YU 7604A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- treatment
- arrythmia
- pyridazinone derivative
- polymorph salt
- polymorph
- Prior art date
Links
- 206010003119 arrhythmia Diseases 0.000 title abstract 2
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- GFNWSKLPHRHAOE-WLHGVMLRSA-N (e)-but-2-enedioic acid;4-chloro-5-[3-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]propylamino]-1h-pyridazin-6-one Chemical compound OC(=O)\C=C\C(O)=O.C1=C(OC)C(OC)=CC=C1CCN(C)CCCNC1=C(Cl)C=NNC1=O GFNWSKLPHRHAOE-WLHGVMLRSA-N 0.000 abstract 1
- 230000006793 arrhythmia Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Treating Waste Gases (AREA)
- Photoreceptors In Electrophotography (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
Abstract
Pronalazak se odnosi na novi kristalni oblik I 5-hloro-4-[3-[2-(3,4-dimetoksi-fenil)etil]-N-metilamino]-propilamino]-3-[2H]-piridazinon fumarata, postupak za njegovo pripremanje, farmaceutske preparate koji sadrže i upotrebu pomenutog novog polimorfa za tretman aritmije.[The invention relates to the new crystalline form I 5-chloro-4-[3-[N-[2-(3,4-dimethoxy-phenyl)-ethyl]-N-methylamino]-propylamino]-3- [2H]-pyridazinone fumarate, a process for the preparation thereof, pharmaceutical compositions containing the same and the use of said new polymorph for the treatment of arrhythmia.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0103064A HUP0103064A3 (en) | 2001-07-26 | 2001-07-26 | Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing it |
Publications (1)
Publication Number | Publication Date |
---|---|
YU7604A true YU7604A (sh) | 2006-08-17 |
Family
ID=89979563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU7604A YU7604A (sh) | 2001-07-26 | 2002-07-26 | Polimorf soli derivata piridazinona za tretman aritmije |
Country Status (15)
Country | Link |
---|---|
US (1) | US20040266772A1 (sh) |
EP (1) | EP1417179A1 (sh) |
JP (1) | JP2004536868A (sh) |
KR (1) | KR20040030861A (sh) |
CN (1) | CN1545505A (sh) |
CA (1) | CA2454774A1 (sh) |
CZ (1) | CZ2004124A3 (sh) |
EA (1) | EA200400222A1 (sh) |
HU (1) | HUP0103064A3 (sh) |
IL (1) | IL159967A0 (sh) |
PL (1) | PL365483A1 (sh) |
SK (1) | SK542004A3 (sh) |
WO (1) | WO2003010150A1 (sh) |
YU (1) | YU7604A (sh) |
ZA (1) | ZA200400483B (sh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU227181B1 (en) * | 2002-09-11 | 2010-09-28 | Egis Gyogyszergyar Nyilvanosan | Use of 5-chloro-4-[3-[n-[2-(3,4-dimethoxyphenyl)ethyl)]-n-methylamino]-propylamino]-3-(2h)-pyridazinone for producing pharmaceutical compositions having metabolic modulator effect |
HU227115B1 (en) * | 2003-10-10 | 2010-07-28 | Egis Gyogyszergyar Nyilvanosan | Pellets containing pyridazinone derivative |
GB201105537D0 (en) * | 2011-03-31 | 2011-05-18 | Vantia Ltd | New process |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU214320B (hu) * | 1991-12-20 | 1998-03-02 | EGIS Gyógyszergyár Rt. | Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
EP1082309B1 (en) * | 1998-06-05 | 2005-09-14 | Egis Gyogyszergyar | Process for the preparation of a 3(2h)-pyridazinone- 4-substituted amino- 5-chloro- derivative |
-
2001
- 2001-07-26 HU HU0103064A patent/HUP0103064A3/hu unknown
-
2002
- 2002-07-26 EP EP02755384A patent/EP1417179A1/en not_active Withdrawn
- 2002-07-26 CA CA002454774A patent/CA2454774A1/en not_active Abandoned
- 2002-07-26 IL IL15996702A patent/IL159967A0/xx unknown
- 2002-07-26 YU YU7604A patent/YU7604A/sh unknown
- 2002-07-26 PL PL02365483A patent/PL365483A1/xx unknown
- 2002-07-26 CZ CZ2004124A patent/CZ2004124A3/cs unknown
- 2002-07-26 CN CNA028162587A patent/CN1545505A/zh active Pending
- 2002-07-26 KR KR10-2004-7001150A patent/KR20040030861A/ko not_active Application Discontinuation
- 2002-07-26 EA EA200400222A patent/EA200400222A1/ru unknown
- 2002-07-26 JP JP2003515509A patent/JP2004536868A/ja active Pending
- 2002-07-26 SK SK54-2004A patent/SK542004A3/sk not_active Application Discontinuation
- 2002-07-26 WO PCT/HU2002/000076 patent/WO2003010150A1/en not_active Application Discontinuation
- 2002-07-26 US US10/484,621 patent/US20040266772A1/en not_active Abandoned
-
2004
- 2004-01-22 ZA ZA200400483A patent/ZA200400483B/en unknown
Also Published As
Publication number | Publication date |
---|---|
HUP0103064A3 (en) | 2005-06-28 |
IL159967A0 (en) | 2004-06-20 |
PL365483A1 (en) | 2005-01-10 |
EP1417179A1 (en) | 2004-05-12 |
JP2004536868A (ja) | 2004-12-09 |
CZ2004124A3 (cs) | 2004-06-16 |
KR20040030861A (ko) | 2004-04-09 |
CN1545505A (zh) | 2004-11-10 |
SK542004A3 (en) | 2004-08-03 |
ZA200400483B (en) | 2005-04-22 |
US20040266772A1 (en) | 2004-12-30 |
WO2003010150A1 (en) | 2003-02-06 |
CA2454774A1 (en) | 2003-02-06 |
HUP0103064A2 (hu) | 2003-02-28 |
EA200400222A1 (ru) | 2004-12-30 |
HU0103064D0 (en) | 2001-10-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
LU91145I2 (fr) | FIROCOXIB facultativement sous forme d'un sel pharmaceutiquement acceptable (PREVICOX). | |
ZA953469B (en) | New compound | |
JO2371B1 (en) | 4-phenyl-pyridine derivatives | |
MY132473A (en) | Crystalline hydrochloride of (r)-(-)-2-<n-[4-(1,1- dioxido-3-oxo-2,3-dihydro-benzisothiazol-2-yl)-butyl]-aminomethyl>-chroman | |
NZ241194A (en) | The pure (-) enantiomer of ((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrozono)propanedinitrile, compositions and new intermediates | |
GB9416219D0 (en) | Receptor ligands | |
MY141661A (en) | 17b-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | |
IL160545A0 (en) | (-)-1-(3,4-dichlorophenyl) -3- azabicyclo [3.1.0] hexane, compositions thereof and uses as a dopamine-reuptake inhibitor | |
NZ287498A (en) | N-(4-indolyl-1-piperazinylethyl)-n-(2-pyridyl)cyclohexanecarboxamide derivatives, preparation and pharmaceutical compositions thereof | |
MY135218A (en) | 2,6-quinolinyl and 2,6-naphthyl derivatives and their use in the treatment of vla-4 dependent diseases | |
JO2321B1 (en) | 4-phenyl-pyridine derivatives | |
GB9209769D0 (en) | Chemical compounds for use as anti-ischemic medicaments | |
HUP0003949A2 (hu) | Vitronektin receptor antagonisták, valamint a vegyületeket tartalmazó gyógyszerkészítmények | |
IL177626A0 (en) | Pharmaceutical compositions for treating sleep apnoea | |
HUP0003931A2 (hu) | Vitronektin receptor antagonisták, valamint a vegyületeket tartalmazó gyógyszerkészítmények | |
BG106293A (en) | Method of inhibiting amyloid protein aggregation and imaging amyloid deposits | |
IL128851A (en) | Pharmaceutical composition for lowering the uric acid level in the human body | |
ES2108595A1 (es) | Derivados de la 3(2h)-piridacinona y procedimiento para su preparacion. | |
YU7604A (sh) | Polimorf soli derivata piridazinona za tretman aritmije | |
CA2462390A1 (en) | Anthranilic acid amides and pharmaceutical use thereof | |
CA2202904A1 (en) | Pharmaceutical composition for prophylaxis and treatment of type i allergic diseases | |
MY133438A (en) | Morpholinobenzamide salts | |
IL112695A (en) | Pharmaceutical compositions containing pyridazinone derivatives | |
HK1046529A1 (zh) | 製備3(2h)-噠嗪酮-4-取代氨基-5-氯-衍生物的方法 | |
NO20042871L (no) | Sitronsyre-salt av en terapeutisk forbindelse og farmasoytiske blandinger derav |