YU73200A - 2-aminopiridini koji sadrže spojene ciklične supstituente kao inhibitori nitro oksid sintaze - Google Patents

2-aminopiridini koji sadrže spojene ciklične supstituente kao inhibitori nitro oksid sintaze

Info

Publication number
YU73200A
YU73200A YU73200A YU73200A YU73200A YU 73200 A YU73200 A YU 73200A YU 73200 A YU73200 A YU 73200A YU 73200 A YU73200 A YU 73200A YU 73200 A YU73200 A YU 73200A
Authority
YU
Yugoslavia
Prior art keywords
nitric oxide
fused ring
oxide synthase
synthase inhibitors
ring substituents
Prior art date
Application number
YU73200A
Other languages
English (en)
Inventor
John Adams Lowe
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of YU73200A publication Critical patent/YU73200A/sh

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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
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    • A61P25/00Drugs for disorders of the nervous system
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    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems

Abstract

Ovaj pronalazak se odnosi na derivate 2-aminopiridina formule (I) pri čemu su R1, R2, nim definisani kao u specifikaciji, na farmaceutske kompozicije koje ih sadrže i na njihovu upotrebu u lečenju i prevenciji centralnog nervnog sistema i drugih oboljenja.[The present invention relates to 2-aminopyridine derivatives of formula (I) wherein R1, R2, n, and m are defined as in the specification, to pharmaceutical compositions containing them and to their use in the treatment and prevention of central nervous system and other disorders.
YU73200A 1998-06-03 1999-05-07 2-aminopiridini koji sadrže spojene ciklične supstituente kao inhibitori nitro oksid sintaze YU73200A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8788198P 1998-06-03 1998-06-03

Publications (1)

Publication Number Publication Date
YU73200A true YU73200A (sh) 2003-02-28

Family

ID=22207822

Family Applications (1)

Application Number Title Priority Date Filing Date
YU73200A YU73200A (sh) 1998-06-03 1999-05-07 2-aminopiridini koji sadrže spojene ciklične supstituente kao inhibitori nitro oksid sintaze

Country Status (35)

Country Link
EP (1) EP1084109B1 (sh)
JP (1) JP3444495B2 (sh)
KR (1) KR20010052515A (sh)
CN (1) CN1303379A (sh)
AP (1) AP1208A (sh)
AR (1) AR016724A1 (sh)
AT (1) ATE287876T1 (sh)
AU (1) AU765851B2 (sh)
BG (1) BG105089A (sh)
BR (1) BR9911615A (sh)
CA (1) CA2334012C (sh)
CO (1) CO5060509A1 (sh)
DE (1) DE69923448T2 (sh)
DZ (1) DZ2807A1 (sh)
EA (1) EA003991B1 (sh)
ES (1) ES2235475T3 (sh)
GT (1) GT199900078A (sh)
HR (1) HRP20000825A2 (sh)
HU (1) HUP0102236A3 (sh)
ID (1) ID27027A (sh)
IL (1) IL139734A0 (sh)
IS (1) IS5726A (sh)
MA (1) MA24872A1 (sh)
NO (1) NO20006042L (sh)
NZ (1) NZ508057A (sh)
OA (1) OA11557A (sh)
PA (1) PA8473501A1 (sh)
PE (1) PE20000554A1 (sh)
PL (1) PL344699A1 (sh)
SK (1) SK17912000A3 (sh)
TN (1) TNSN99105A1 (sh)
UY (1) UY25539A1 (sh)
WO (1) WO1999062883A1 (sh)
YU (1) YU73200A (sh)
ZA (1) ZA993699B (sh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010114213A (ko) 1999-02-25 2001-12-31 실버스타인 아써 에이. 접합 고리 치환기를 함유한 2-아미노피리딘
GB0004151D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004149D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
GB0004153D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004152D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
SE0102640D0 (sv) 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW432073B (en) * 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
HN1996000101A (es) * 1996-02-28 1997-06-26 Inc Pfizer Terapia combinada para la osteoporosis
PT891332E (pt) * 1996-03-29 2004-07-30 Pfizer Derivados de 6-fenilpiridil-2-amina
BR9811093A (pt) * 1997-02-10 2000-07-18 Pfizer Prod Inc Piridinas substituìdas com 2-amino-6-(4-fenóxi 2-substituìdo)
HN1998000118A (es) * 1997-08-27 1999-02-09 Pfizer Prod Inc 2 - aminopiridinas que contienen sustituyentes de anillos condensados.

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Publication number Publication date
NZ508057A (en) 2003-07-25
HRP20000825A2 (en) 2001-12-31
BR9911615A (pt) 2001-02-06
KR20010052515A (ko) 2001-06-25
PA8473501A1 (es) 2000-09-29
GT199900078A (es) 2000-11-22
JP2002516907A (ja) 2002-06-11
EP1084109A1 (en) 2001-03-21
DE69923448D1 (de) 2005-03-03
CA2334012A1 (en) 1999-12-09
AP9901558A0 (en) 1999-06-30
DZ2807A1 (fr) 2003-12-01
EA200001143A1 (ru) 2001-06-25
SK17912000A3 (sk) 2001-09-11
IS5726A (is) 2000-11-24
NO20006042D0 (no) 2000-11-29
JP3444495B2 (ja) 2003-09-08
CA2334012C (en) 2006-05-02
NO20006042L (no) 2001-01-31
MA24872A1 (fr) 1999-12-31
AU3438799A (en) 1999-12-20
ATE287876T1 (de) 2005-02-15
EA003991B1 (ru) 2003-12-25
TNSN99105A1 (fr) 2005-11-10
AU765851B2 (en) 2003-10-02
AP1208A (en) 2003-09-29
OA11557A (en) 2004-05-24
DE69923448T2 (de) 2005-12-29
ZA993699B (en) 2000-12-01
IL139734A0 (en) 2002-02-10
PL344699A1 (en) 2001-11-19
PE20000554A1 (es) 2000-07-08
EP1084109B1 (en) 2005-01-26
WO1999062883A1 (en) 1999-12-09
BG105089A (en) 2001-09-28
AR016724A1 (es) 2001-07-25
ES2235475T3 (es) 2005-07-01
ID27027A (id) 2001-02-22
CO5060509A1 (es) 2001-07-30
HUP0102236A3 (en) 2003-01-28
UY25539A1 (es) 2000-12-29
CN1303379A (zh) 2001-07-11
HUP0102236A2 (hu) 2001-11-28

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