YU49699A - Farmaceutska kompozicija i postupak njenog dobijanja - Google Patents

Farmaceutska kompozicija i postupak njenog dobijanja

Info

Publication number
YU49699A
YU49699A YU49699A YU49699A YU49699A YU 49699 A YU49699 A YU 49699A YU 49699 A YU49699 A YU 49699A YU 49699 A YU49699 A YU 49699A YU 49699 A YU49699 A YU 49699A
Authority
YU
Yugoslavia
Prior art keywords
production
pharmaceutical compositions
composition
hydrogel matrix
bioactive
Prior art date
Application number
YU49699A
Other languages
English (en)
Inventor
Nicholas Peppas
Anthony Lowman
Tsuneji Nagai
Mariko Morishita
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of YU49699A publication Critical patent/YU49699A/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Opisani su kompozicija za oralnu primenu bioaktivnih komponenata na kičmenjake i postupak za dobijanje te kompozicije. Kompozicija se sastoji od hidrogel matrice koja može da bubri i labilnog proteina. Hidrogel matrica uključuje poprečno umreženi kopolimer metakrilne kiseline i poli(alkilen glikol) monometakrilat, a labilni protein može biti insulin.[A composition and method are described for the oral administration of bioactive components to vertebrates. The method comprises the step of orally administering the vertebrate a composition comprising a swellable hydrogel matrix and a bioactive composition contained within the hydrogel matrix.
YU49699A 1997-04-02 1998-04-02 Farmaceutska kompozicija i postupak njenog dobijanja YU49699A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4228097P 1997-04-02 1997-04-02
US6136797P 1997-10-08 1997-10-08

Publications (1)

Publication Number Publication Date
YU49699A true YU49699A (sh) 2002-12-10

Family

ID=26719055

Family Applications (1)

Application Number Title Priority Date Filing Date
YU49699A YU49699A (sh) 1997-04-02 1998-04-02 Farmaceutska kompozicija i postupak njenog dobijanja

Country Status (14)

Country Link
EP (1) EP0975328A1 (sh)
JP (1) JP2002512607A (sh)
KR (1) KR20010005952A (sh)
CN (1) CN1259045A (sh)
AU (1) AU727053B2 (sh)
BR (1) BR9808466A (sh)
CA (1) CA2285457A1 (sh)
IL (1) IL132176A0 (sh)
NO (1) NO994757L (sh)
NZ (1) NZ500075A (sh)
PL (1) PL335974A1 (sh)
TR (1) TR199903240T2 (sh)
WO (1) WO1998043615A1 (sh)
YU (1) YU49699A (sh)

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US6878384B2 (en) 2001-03-13 2005-04-12 Microvention, Inc. Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use
DE60318938T2 (de) 2002-03-20 2009-01-22 Mannkind Corp., Valencia Inhalationsgerät
ES2385934T3 (es) 2004-08-20 2012-08-03 Mannkind Corporation Catálisis de la síntesis de dicetopiperazina.
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
US8110212B2 (en) 2005-04-07 2012-02-07 Drexel University Bioactive thermogelling polymer systems and methods of their use
AU2005334837B2 (en) 2005-07-29 2012-07-19 Stichting Groningen Centre For Drug Research PH-controlled pulsatile delivery system, methods for preparation and use thereof
JP2009503093A (ja) * 2005-08-01 2009-01-29 マンカインド コーポレイション インスリン産生細胞の機能を保持する方法
KR20160022404A (ko) 2005-09-14 2016-02-29 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
MX2008010721A (es) 2006-02-22 2008-09-01 Mannkind Corp Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo.
EP2027729A2 (en) 2006-06-15 2009-02-25 MicroVention, Inc. Embolization device constructed from expansible polymer
BRPI0821070B1 (pt) 2007-12-21 2018-10-23 Microvention Inc dispositivo para implantação e método para a preparação de um filamento de hidrogel para implantação em um animal
EP3281663B8 (en) 2008-06-13 2022-09-21 MannKind Corporation Breath powered dry powder inhaler for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8551528B2 (en) 2009-06-12 2013-10-08 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
HUP0900482A2 (en) 2009-08-03 2011-03-28 Cera Med Kft Pharmaceutical formulation for oral administration
KR20120090052A (ko) 2009-09-24 2012-08-16 마이크로벤션, 인코포레이티드 생물 의학적 사용을 위한 주사가능한 히드로겔 필라멘트
CA2777171C (en) 2009-10-26 2017-09-19 Microvention, Inc. Embolization device constructed from expansile polymer
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
KR101940832B1 (ko) 2011-04-01 2019-01-21 맨카인드 코포레이션 의약 카트리지용 블리스터 패키지
US9456823B2 (en) 2011-04-18 2016-10-04 Terumo Corporation Embolic devices
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EP2776053A1 (en) 2011-10-24 2014-09-17 MannKind Corporation Methods and compositions for treating pain
WO2013158781A1 (en) 2012-04-18 2013-10-24 Microvention, Inc. Embolic devices
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
BR122019026637B1 (pt) 2013-07-18 2023-09-26 Mannkind Corporation Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
WO2015021044A1 (en) * 2013-08-05 2015-02-12 University Of Rochester Compositions and methods for stimuli-responsive release of a therapeutic agent
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
WO2015153996A1 (en) 2014-04-03 2015-10-08 Micro Vention, Inc. Embolic devices
US10092663B2 (en) 2014-04-29 2018-10-09 Terumo Corporation Polymers
JP6599361B2 (ja) 2014-04-29 2019-10-30 マイクロベンション インコーポレイテッド 活性剤を含むポリマー
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US10265405B2 (en) 2014-11-18 2019-04-23 Board Of Regents, The University Of Texas System Polymers for delivery of factor VIII and/or factor IX
WO2016201250A1 (en) 2015-06-11 2016-12-15 Microvention, Inc. Expansile device for implantation

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US2976576A (en) * 1956-04-24 1961-03-28 Wichterle Otto Process for producing shaped articles from three-dimensional hydrophilic high polymers
US3220960A (en) * 1960-12-21 1965-11-30 Wichterle Otto Cross-linked hydrophilic polymers and articles made therefrom
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Also Published As

Publication number Publication date
AU727053B2 (en) 2000-11-30
KR20010005952A (ko) 2001-01-15
IL132176A0 (en) 2001-03-19
CN1259045A (zh) 2000-07-05
JP2002512607A (ja) 2002-04-23
NZ500075A (en) 2001-03-30
BR9808466A (pt) 2001-08-07
NO994757D0 (no) 1999-09-30
NO994757L (no) 1999-11-29
EP0975328A1 (en) 2000-02-02
AU6880998A (en) 1998-10-22
WO1998043615A1 (en) 1998-10-08
CA2285457A1 (en) 1998-10-08
PL335974A1 (en) 2000-06-05
TR199903240T2 (xx) 2000-05-22

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