YU48398A - Inhibitori halo-supstituisane protein kinaze c - Google Patents
Inhibitori halo-supstituisane protein kinaze cInfo
- Publication number
- YU48398A YU48398A YU48398A YU48398A YU48398A YU 48398 A YU48398 A YU 48398A YU 48398 A YU48398 A YU 48398A YU 48398 A YU48398 A YU 48398A YU 48398 A YU48398 A YU 48398A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- protein kinase
- halo
- supstituted
- inhibitors
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Ovaj pronalazak ima za cilj da inovira halo-supstituisani bis-indolmalimid jedinjenja formule: Pronalazak daje postupak dobijanja izloženih jedinjenja i spravljanje farmaceutskih formulacija za upotrebu u inhibiciji Protein Kinaze C kod sisara.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1638296P | 1996-05-01 | 1996-05-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU48398A true YU48398A (sh) | 2000-12-28 |
Family
ID=21776838
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU48398A YU48398A (sh) | 1996-05-01 | 1997-04-30 | Inhibitori halo-supstituisane protein kinaze c |
Country Status (21)
Country | Link |
---|---|
US (1) | US5936084A (sh) |
EP (1) | EP0805158B1 (sh) |
JP (1) | JP3235840B2 (sh) |
KR (1) | KR20000065137A (sh) |
AT (1) | ATE212026T1 (sh) |
AU (1) | AU703395B2 (sh) |
BR (1) | BR9709301A (sh) |
CA (1) | CA2252701C (sh) |
CZ (1) | CZ347098A3 (sh) |
DE (1) | DE69709568T2 (sh) |
DK (1) | DK0805158T3 (sh) |
EA (1) | EA001450B1 (sh) |
ES (1) | ES2170918T3 (sh) |
IL (1) | IL126762A0 (sh) |
NO (1) | NO310416B1 (sh) |
NZ (1) | NZ332658A (sh) |
PL (1) | PL329681A1 (sh) |
PT (1) | PT805158E (sh) |
TR (1) | TR199802193T2 (sh) |
WO (1) | WO1997041127A1 (sh) |
YU (1) | YU48398A (sh) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6127401A (en) | 1998-06-05 | 2000-10-03 | Cephalon, Inc. | Bridged indenopyrrolocarbazoles |
US7425537B2 (en) * | 2000-08-22 | 2008-09-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | SH2 domain binding inhibitors |
ES2245994T3 (es) * | 2000-12-08 | 2006-02-01 | Ortho-Mcneil Pharmaceutical, Inc. | Compuestos macro-heterociclicos utilizados como inhibidores de quinasa. |
WO2003037384A2 (en) * | 2001-10-29 | 2003-05-08 | Nektar Therapeutics Al, Corporation | Polymer conjugates of protein kinase c inhibitors |
WO2003099284A1 (en) | 2002-05-22 | 2003-12-04 | Amgen Inc. | Amino-pyridine, -pyridine and pyridazine derivatives for use as vanilloid receptor ligands for the treatment of pain |
RS20050161A (en) | 2002-08-08 | 2007-09-21 | Amgen Inc., | Vanilloid receptor ligands and their use in treatments |
DE10244453A1 (de) * | 2002-09-24 | 2004-04-01 | Phenomiques Gmbh | Hemmung der Proteinkinase C-alpha zur Behandlung von Krankheiten |
US7245117B1 (en) * | 2004-11-01 | 2007-07-17 | Cardiomems, Inc. | Communicating with implanted wireless sensor |
WO2005077938A1 (en) * | 2004-02-11 | 2005-08-25 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
MY139645A (en) | 2004-02-11 | 2009-10-30 | Amgen Inc | Vanilloid receptor ligands and their use in treatments |
CN101023094B (zh) | 2004-07-21 | 2011-05-18 | 法莫赛特股份有限公司 | 烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备 |
AU2005285045B2 (en) | 2004-09-14 | 2011-10-13 | Gilead Pharmasset Llc | Preparation of 2'fluoro-2'- alkyl- substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives |
WO2006089311A1 (en) | 2005-02-15 | 2006-08-24 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
US8158586B2 (en) * | 2005-04-11 | 2012-04-17 | Pharmagap Inc. | Inhibitors of protein kinases and uses thereof |
WO2006113769A1 (en) * | 2005-04-15 | 2006-10-26 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
WO2010049947A2 (en) * | 2008-10-28 | 2010-05-06 | Accrete Pharmaceutical Private Limited | Preparation of gemcitabine and intermediates thereof |
CA2764653C (en) * | 2009-06-10 | 2018-01-02 | Chugai Seiyaku Kabushiki Kaisha | Tetracyclic compounds |
ES2769550T3 (es) | 2010-08-20 | 2020-06-26 | Chugai Pharmaceutical Co Ltd | Composición que comprende un compuesto tetracíclico |
SG10201704588XA (en) | 2012-09-25 | 2017-07-28 | Chugai Pharmaceutical Co Ltd | Ret inhibitor |
TWI771839B (zh) | 2014-04-25 | 2022-07-21 | 日商中外製藥股份有限公司 | 以高用量含有4環性化合物的製劑 |
CA2946268A1 (en) | 2014-04-25 | 2015-10-29 | Chugai Seiyaku Kabushiki Kaisha | Crystal of tetracyclic compound |
TWI803187B (zh) | 2014-08-08 | 2023-05-21 | 日商中外製藥股份有限公司 | 包含4環性化合物的非晶質體之固體分散體及製劑 |
WO2016114375A1 (ja) | 2015-01-16 | 2016-07-21 | 中外製薬株式会社 | 併用医薬 |
WO2019000224A1 (zh) * | 2017-06-27 | 2019-01-03 | 中国海洋大学 | 双吲哚马来酰亚胺衍生物及其制备方法和用途 |
SG11202100983XA (en) | 2018-09-04 | 2021-03-30 | Chugai Pharmaceutical Co Ltd | Method of producing tetracyclic compound |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5438050A (en) * | 1988-02-06 | 1995-08-01 | Godecke Aktiengesellschaft | Indolocarbazole derivatives, processes for their preparation and compositions containing them |
US5380746A (en) * | 1989-05-05 | 1995-01-10 | Goedecke Aktiengesellschaft | Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them |
US5589472A (en) * | 1992-09-25 | 1996-12-31 | Vice; Susan F. | Diindolo compounds and pharmaceutical compositions containing them |
JP3581731B2 (ja) * | 1993-12-07 | 2004-10-27 | イーライ・リリー・アンド・カンパニー | プロテインキナーゼc阻害物質 |
US5624949A (en) * | 1993-12-07 | 1997-04-29 | Eli Lilly And Company | Protein kinase C inhibitors |
US5472183A (en) * | 1994-03-17 | 1995-12-05 | Nisca Corporation | Sheet feeding device with multiple sheet stackers |
US5559228A (en) * | 1995-03-30 | 1996-09-24 | Eli Lilly And Company | Synthesis of bisindolylmaleimides |
US5696949A (en) * | 1995-06-15 | 1997-12-09 | Intel Corporation | System for PCI slots expansion using asynchronous PCI-to-PCI bridge with clock generator for providing clock signal to the expansion mother board and expansion side of bridge |
-
1997
- 1997-04-30 PL PL97329681A patent/PL329681A1/xx unknown
- 1997-04-30 BR BR9709301A patent/BR9709301A/pt unknown
- 1997-04-30 EA EA199800966A patent/EA001450B1/ru not_active IP Right Cessation
- 1997-04-30 NZ NZ332658A patent/NZ332658A/xx unknown
- 1997-04-30 US US08/846,272 patent/US5936084A/en not_active Expired - Fee Related
- 1997-04-30 IL IL12676297A patent/IL126762A0/xx unknown
- 1997-04-30 WO PCT/US1997/007302 patent/WO1997041127A1/en not_active Application Discontinuation
- 1997-04-30 CA CA002252701A patent/CA2252701C/en not_active Expired - Fee Related
- 1997-04-30 KR KR1019980708737A patent/KR20000065137A/ko active IP Right Grant
- 1997-04-30 TR TR1998/02193T patent/TR199802193T2/xx unknown
- 1997-04-30 CZ CZ983470A patent/CZ347098A3/cs unknown
- 1997-04-30 YU YU48398A patent/YU48398A/sh unknown
- 1997-04-30 JP JP52234397A patent/JP3235840B2/ja not_active Expired - Fee Related
- 1997-04-30 AU AU29292/97A patent/AU703395B2/en not_active Ceased
- 1997-05-01 EP EP97302996A patent/EP0805158B1/en not_active Expired - Lifetime
- 1997-05-01 AT AT97302996T patent/ATE212026T1/de not_active IP Right Cessation
- 1997-05-01 ES ES97302996T patent/ES2170918T3/es not_active Expired - Lifetime
- 1997-05-01 DK DK97302996T patent/DK0805158T3/da active
- 1997-05-01 DE DE69709568T patent/DE69709568T2/de not_active Expired - Fee Related
- 1997-05-01 PT PT97302996T patent/PT805158E/pt unknown
-
1998
- 1998-10-30 NO NO19985080A patent/NO310416B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP3235840B2 (ja) | 2001-12-04 |
NO985080D0 (no) | 1998-10-30 |
KR20000065137A (ko) | 2000-11-06 |
NZ332658A (en) | 2000-05-26 |
US5936084A (en) | 1999-08-10 |
EP0805158A3 (en) | 1998-04-01 |
EP0805158B1 (en) | 2002-01-16 |
DK0805158T3 (da) | 2002-03-18 |
DE69709568D1 (de) | 2002-02-21 |
NO310416B1 (no) | 2001-07-02 |
DE69709568T2 (de) | 2002-09-05 |
TR199802193T2 (xx) | 1999-02-22 |
AU703395B2 (en) | 1999-03-25 |
CZ347098A3 (cs) | 1999-06-16 |
CA2252701A1 (en) | 1997-11-06 |
AU2929297A (en) | 1997-11-19 |
WO1997041127A1 (en) | 1997-11-06 |
PL329681A1 (en) | 1999-04-12 |
BR9709301A (pt) | 1999-08-10 |
CA2252701C (en) | 2003-10-28 |
EA001450B1 (ru) | 2001-04-23 |
IL126762A0 (en) | 1999-08-17 |
ES2170918T3 (es) | 2002-08-16 |
JPH11509233A (ja) | 1999-08-17 |
ATE212026T1 (de) | 2002-02-15 |
EP0805158A2 (en) | 1997-11-05 |
NO985080L (no) | 1998-12-08 |
EA199800966A1 (ru) | 1999-04-29 |
PT805158E (pt) | 2002-06-28 |
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