YU46956B - Postupak za dobivanje novih berban derivata - Google Patents

Postupak za dobivanje novih berban derivata

Info

Publication number
YU46956B
YU46956B YU84886A YU84886A YU46956B YU 46956 B YU46956 B YU 46956B YU 84886 A YU84886 A YU 84886A YU 84886 A YU84886 A YU 84886A YU 46956 B YU46956 B YU 46956B
Authority
YU
Yugoslavia
Prior art keywords
sup
sub
group
straight
carbon atoms
Prior art date
Application number
YU84886A
Other languages
English (en)
Other versions
YU84886A (en
Inventor
S. Vizi
C. Szantai
L. Szabo
I. Toth
G. Kovacs
J. Marton
L. Harsing
G. Somogy
J. Gall
Original Assignee
Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. filed Critical Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.
Publication of YU84886A publication Critical patent/YU84886A/xx
Publication of YU46956B publication Critical patent/YU46956B/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, ***e
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Emergency Protection Circuit Devices (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Train Traffic Observation, Control, And Security (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

POSTUPAK ZA DOBIVANJE NOVIH BERBAN DERIVATA racemskih ili optički aktivnih jedinjenja opšte formule gde R1 i R2 svaki nezavisno je hidroksi, normalnog ili račvastog lanca alkoksi grupa koja ima 1-6 atoma ugljenika ili R1 i R2 zajedno su C1-3 alkilendioksi grupa, R3 i R4 svaki nezavisno je vodonik, normalnog ili račvastog lanca alkil grupa koja ima 1-4 atoma ugljenika i po izboru supstituisanu sa hidroksi grupom ili C2-6alkoksikarbonil grupu, i R5 je vodonik, normalnog ili račvastog lanca alkil grupa koja ima 1-6 atoma ugljenika, C1-7alifatična ili aromatična acil grupa ili C1-7alkilsulfonil ili arilsulfonil grupa, i njihovih soli, naznačen time, što se redukuje okso grupa racemskog ili optički aktivnog jedinjenja opšte formule gde R1, R2, R3 i R4 su kao što je definisano napred, posle čega se po izboru vrši alkilovanje ili acilovanje dobivenog jedinjenja opšte formule I, gde R1, R2, R3 i R4 imaju napred data značenja a R5 je vodonik, tako da se dobiva jedinjenje opšte formule I, gde R1, R2, R3 i R4 imaju napred data značenja i gde R5 ima napred data značenja sem vodonika i po izboru se dalje vrši razlaganje dobivenog jedinjenja opšte formule I, ili se ono prevodi u so ili se oslobadja iz svoje soli. Prijava sadrži još 8 zavisnih zahteva.
YU84886A 1985-05-24 1986-05-21 Postupak za dobivanje novih berban derivata YU46956B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU851982A HU195505B (en) 1985-05-24 1985-05-24 Process for producing 7,8-methylendioxy-14-hydroxy-berban derivatives and pharmaceuticals comprising the same

Publications (2)

Publication Number Publication Date
YU84886A YU84886A (en) 1989-08-31
YU46956B true YU46956B (sh) 1994-09-09

Family

ID=10957145

Family Applications (1)

Application Number Title Priority Date Filing Date
YU84886A YU46956B (sh) 1985-05-24 1986-05-21 Postupak za dobivanje novih berban derivata

Country Status (26)

Country Link
US (1) US4851416A (sh)
EP (1) EP0202950B1 (sh)
JP (1) JPS61280492A (sh)
KR (1) KR870001742B1 (sh)
CN (1) CN1010779B (sh)
AT (1) ATE95180T1 (sh)
AU (1) AU599030B2 (sh)
CA (1) CA1294964C (sh)
CS (1) CS266586B2 (sh)
DD (1) DD251289A5 (sh)
DE (1) DE3689080T2 (sh)
DK (1) DK242886A (sh)
ES (1) ES8800938A1 (sh)
FI (1) FI85023C (sh)
GR (1) GR861348B (sh)
HU (1) HU195505B (sh)
IE (1) IE60479B1 (sh)
IL (1) IL78722A (sh)
NO (1) NO164098C (sh)
NZ (1) NZ216280A (sh)
PH (1) PH24053A (sh)
PL (1) PL148617B1 (sh)
PT (1) PT82634B (sh)
SU (2) SU1508958A3 (sh)
YU (1) YU46956B (sh)
ZA (1) ZA863869B (sh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5122504A (en) * 1990-02-27 1992-06-16 The Board Of Trustees Of The Leland Stanford Junior University Superconducting ribbon process using laser heating
WO1992020678A1 (en) * 1991-05-22 1992-11-26 Chinoin Gyógyszer- És Vegyészeti Gyár R.T. New berbane derivatives, pharmaceutical compositions containing these compounds and process for the preparation of same
US5492907A (en) * 1992-12-09 1996-02-20 The United States Of America As Represented By The Department Of Health & Human Services Antipsychotic composition and method of treatment
US5663167A (en) * 1992-12-09 1997-09-02 The United States Of America As Represented By The Department Of Health And Human Services Antipsychotic composition and method of treatment

Also Published As

Publication number Publication date
US4851416A (en) 1989-07-25
CS266586B2 (en) 1990-01-12
ES555206A0 (es) 1987-12-16
ZA863869B (en) 1987-02-25
DK242886D0 (da) 1986-05-23
FI862174A (fi) 1986-11-25
CS376786A2 (en) 1989-04-14
IE861373L (en) 1986-11-24
AU599030B2 (en) 1990-07-12
YU84886A (en) 1989-08-31
KR860009014A (ko) 1986-12-19
NO164098B (no) 1990-05-21
IE60479B1 (en) 1994-07-13
IL78722A0 (en) 1986-08-31
CA1294964C (en) 1992-01-28
PL148617B1 (en) 1989-11-30
FI862174A0 (fi) 1986-05-23
IL78722A (en) 1990-03-19
NO862054L (no) 1986-11-25
AU5785386A (en) 1986-11-27
DD251289A5 (de) 1987-11-11
EP0202950B1 (en) 1993-09-29
PT82634A (en) 1986-06-01
KR870001742B1 (ko) 1987-09-26
NZ216280A (en) 1989-08-29
NO164098C (no) 1990-08-29
ES8800938A1 (es) 1987-12-16
GR861348B (en) 1986-09-23
PH24053A (en) 1990-03-05
EP0202950A3 (en) 1988-03-23
SU1508958A3 (ru) 1989-09-15
HU195505B (en) 1988-05-30
CN86103519A (zh) 1986-12-03
SU1573021A1 (ru) 1990-06-23
FI85023C (fi) 1992-02-25
PT82634B (pt) 1988-03-03
ATE95180T1 (de) 1993-10-15
JPS61280492A (ja) 1986-12-11
EP0202950A2 (en) 1986-11-26
DK242886A (da) 1986-11-25
DE3689080D1 (de) 1993-11-04
DE3689080T2 (de) 1994-01-27
CN1010779B (zh) 1990-12-12
HUT40651A (en) 1987-01-28
FI85023B (fi) 1991-11-15

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