YU46919B - Postupak za dobijanje derivata l-alanil-l-prolina - Google Patents
Postupak za dobijanje derivata l-alanil-l-prolinaInfo
- Publication number
- YU46919B YU46919B YU135588A YU135588A YU46919B YU 46919 B YU46919 B YU 46919B YU 135588 A YU135588 A YU 135588A YU 135588 A YU135588 A YU 135588A YU 46919 B YU46919 B YU 46919B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- formula
- alanyl
- preparation
- proline
- proline derivatives
- Prior art date
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
POSTUPAK ZA DOBIJANJE DERIVATA L-ALANIL-L-PROLINA, i njihovih farmaceutski prihvatljivih soli, naznačen time, što se N,O-bistrimetil sili-L-prolin formule II kondenzuje sa derivatom N-/1(S)-etoksikarbonil-3-fenilpropil/-L-alanina opšte formule III u kojoj Het označava ostatak imidazola-1 ili 2-tiobenzotiazola, u nepolarnim organskim rastvaračima, kao što su dioksan, tetrahidrofuran i metilenhlorid, prvenstveno tetrahidrofuran, u temperaturnom intervalu od -10 do 20 C i po želji dobijeno jedinjenje formule I, gde je R etil, hidrolizuje u jedinjenje formule I, gde je R vodonik.
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU135588A YU46919B (sh) | 1988-07-13 | 1988-07-13 | Postupak za dobijanje derivata l-alanil-l-prolina |
SI8811355A SI8811355A (en) | 1988-07-13 | 1988-07-13 | Process for preparing of L-alanine-L-proline derivatives |
NO892813A NO172894C (no) | 1988-07-13 | 1989-07-07 | Fremgangsmaate til fremstilling av l-alanyl-l-prolinderivater |
ES8902425A ES2015723A6 (es) | 1988-07-13 | 1989-07-10 | Un procedimiento para la preparacion de derivados de l-alanil-l-prolina. |
AT168189A AT394726B (de) | 1988-07-13 | 1989-07-11 | Verfahren zur herstellung von l-alanyl-l-prolin-derivaten |
PL28052689A PL154625B1 (en) | 1988-07-13 | 1989-07-11 | Method of obtaining l-alanyl-l-proline |
DD33068889A DD284028B5 (de) | 1988-07-13 | 1989-07-11 | Verfahren zur Herstellung von L-Alanyl-L-prolin-Derivaten |
SU894614532A SU1757471A3 (ru) | 1988-07-13 | 1989-07-12 | Способ получени производных L-аланил-L-пролина или их фармацевтически приемлемых солей |
UA4614532A UA18634A1 (uk) | 1988-07-13 | 1989-07-12 | Спосіб одердаhhя похідhих l-алаhіл-l-пропіліhа або їх фармацевтичhо прийhятhих солей |
JP1179211A JP2714447B2 (ja) | 1988-07-13 | 1989-07-13 | L―アラニル―l―プロリン誘導体の製造方法 |
LV930829A LV5528A3 (lv) | 1988-07-13 | 1993-06-30 | L-alanil-l-prolina atvasinajumu vai to farmaceitiski derigu salu iegusanas panemiens |
LTRP821A LT2188B (lt) | 1988-07-13 | 1993-07-29 | L-analil-l-prolino dariniu arba ju farmaceutiskai priimtinu drusku gavimo budas |
HRP-1355/88A HRP931139B1 (en) | 1988-07-13 | 1993-08-19 | Proces for the preparation of l-alanyl-proline derivates |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU135588A YU46919B (sh) | 1988-07-13 | 1988-07-13 | Postupak za dobijanje derivata l-alanil-l-prolina |
Publications (2)
Publication Number | Publication Date |
---|---|
YU135588A YU135588A (en) | 1990-02-28 |
YU46919B true YU46919B (sh) | 1994-06-24 |
Family
ID=25553829
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU135588A YU46919B (sh) | 1988-07-13 | 1988-07-13 | Postupak za dobijanje derivata l-alanil-l-prolina |
Country Status (10)
Country | Link |
---|---|
JP (1) | JP2714447B2 (sh) |
AT (1) | AT394726B (sh) |
DD (1) | DD284028B5 (sh) |
ES (1) | ES2015723A6 (sh) |
NO (1) | NO172894C (sh) |
PL (1) | PL154625B1 (sh) |
SI (1) | SI8811355A (sh) |
SU (1) | SU1757471A3 (sh) |
UA (1) | UA18634A1 (sh) |
YU (1) | YU46919B (sh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005010028A1 (en) * | 2003-07-31 | 2005-02-03 | Lupin Limited | Alpha-amino acid benzothiazolylthio ester as intermediates for manufacture of ace inhibitors and process for preparation thereof |
US20100204470A1 (en) * | 2006-06-27 | 2010-08-12 | Sandoz Ag | method for salt preparation |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4442089A (en) * | 1982-07-06 | 1984-04-10 | E. R. Squibb & Sons, Inc. | Method for treating glaucoma with topical or systemic ACE inhibitor compositions |
JPS6248696A (ja) * | 1985-08-27 | 1987-03-03 | Kanegafuchi Chem Ind Co Ltd | N−〔1(s)−エトキシカルボニル−3−フエニルプロピル〕−l−アラニル−l−プロリンの製造法 |
-
1988
- 1988-07-13 SI SI8811355A patent/SI8811355A/sl unknown
- 1988-07-13 YU YU135588A patent/YU46919B/sh unknown
-
1989
- 1989-07-07 NO NO892813A patent/NO172894C/no unknown
- 1989-07-10 ES ES8902425A patent/ES2015723A6/es not_active Expired - Lifetime
- 1989-07-11 PL PL28052689A patent/PL154625B1/pl unknown
- 1989-07-11 DD DD33068889A patent/DD284028B5/de active IP Right Maintenance
- 1989-07-11 AT AT168189A patent/AT394726B/de not_active IP Right Cessation
- 1989-07-12 UA UA4614532A patent/UA18634A1/uk unknown
- 1989-07-12 SU SU894614532A patent/SU1757471A3/ru active
- 1989-07-13 JP JP1179211A patent/JP2714447B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2714447B2 (ja) | 1998-02-16 |
PL154625B1 (en) | 1991-08-30 |
NO892813L (no) | 1990-01-15 |
SI8811355A (en) | 1995-04-30 |
YU135588A (en) | 1990-02-28 |
NO892813D0 (no) | 1989-07-07 |
AT394726B (de) | 1992-06-10 |
JPH0272195A (ja) | 1990-03-12 |
ES2015723A6 (es) | 1990-09-01 |
PL280526A1 (en) | 1990-02-05 |
DD284028B5 (de) | 1996-08-08 |
NO172894C (no) | 1993-09-22 |
SU1757471A3 (ru) | 1992-08-23 |
NO172894B (no) | 1993-06-14 |
UA18634A1 (uk) | 1997-12-25 |
ATA168189A (de) | 1991-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA1104569A (en) | Transient pro-drug forms of xanthine derivatives | |
NO2015020I2 (no) | Ceritinib eller et farmasøytisk akseptabelt salt derav | |
PT97888A (pt) | Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem | |
AU528275B2 (en) | Imidazole derivatives | |
DK534381A (da) | Fremgangsmaade til fremstilling af 2-oxoazetidinderivater | |
YU45695B (sh) | Postupak za dobijanje novih 6-alkiliden-penema sa beta-laktamaza inhibitorskim i antibakterijskim osobinama | |
NO944749L (no) | Nye steroider med pregnanskjelett, farmasöytiske preparater inneholdende disse, og fremgangsmåte for fremtilling av disse | |
TW238304B (en) | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | |
YU46919B (sh) | Postupak za dobijanje derivata l-alanil-l-prolina | |
YU46647B (sh) | Postupak za dobijanje hinolinskih derivata | |
AU556922B2 (en) | Pyridobenzodiazepinone derivatives | |
DK605484A (da) | Imidazo-(1,2-a)-pyrimidiner og fremgangsmaade til fremstilling deraf | |
ES2016017A6 (es) | Procedimiento para preparar derivados de acido 1,1-dioxocefem-4-carbotiolico. | |
JPS57140776A (en) | Preparation of 2-aminothiazol-4-yl-alpha-oximinoacetic acid derivative | |
CA2053705A1 (en) | Piperazine derivatives | |
JPS5610193A (en) | Preparation of rifamycin derivative | |
ATE75468T1 (de) | Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung. | |
YU46067B (sh) | Postupak za dobijanje hinazolindiona i piridopirimidindiona | |
JPS55104266A (en) | Novel pyridone derivative | |
GB765047A (en) | Heterocyclic nitrogen compounds and methods for obtaining the same | |
ES8200084A1 (es) | Procedimiento de producir compuestos organicos aminobenzami-dicos | |
TH13791A (th) | อนุพันธ์ต่างๆของกรดบิวไทริค | |
TH6636EX (th) | อนุพันธ์ของควิโนลีน กรรมวิธีสำหรับการเตรียมสารเหล่านั้นและสารต่อต้านแบคทีเรีย ที่มีสารเหล่านั้นอนุพันธ์ของควิโนลีน กรรมวิธีสำหรับการเตรียมสารเหล่านั้นและสารต่อต้านแบคทีเรีย ที่มีสารเหล่านั้น | |
JPS51133271A (en) | Process for preparing heterocyclic compounds | |
YU48893A (sh) | Postupak za sintezu 17 alfa-metil-17-propionilestra-4,9-dien-3-ona |