YU45346B - Process for obtaining pharmaceutical active 1-substituted oxindole-3-carboxamide - Google Patents

Process for obtaining pharmaceutical active 1-substituted oxindole-3-carboxamide

Info

Publication number
YU45346B
YU45346B YU1203/86A YU120386A YU45346B YU 45346 B YU45346 B YU 45346B YU 1203/86 A YU1203/86 A YU 1203/86A YU 120386 A YU120386 A YU 120386A YU 45346 B YU45346 B YU 45346B
Authority
YU
Yugoslavia
Prior art keywords
carboxamide
pharmaceutical active
substituted oxindole
substituted
obtaining pharmaceutical
Prior art date
Application number
YU1203/86A
Other languages
English (en)
Other versions
YU120386A (en
Inventor
S B Kadin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/825,017 external-priority patent/US4678802A/en
Application filed by Pfizer filed Critical Pfizer
Publication of YU120386A publication Critical patent/YU120386A/xx
Publication of YU45346B publication Critical patent/YU45346B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
YU1203/86A 1985-07-09 1986-07-08 Process for obtaining pharmaceutical active 1-substituted oxindole-3-carboxamide YU45346B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75320085A 1985-07-09 1985-07-09
US82129686A 1986-01-22 1986-01-22
US06/825,017 US4678802A (en) 1985-07-09 1986-01-31 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents

Publications (2)

Publication Number Publication Date
YU120386A YU120386A (en) 1988-02-29
YU45346B true YU45346B (en) 1992-05-28

Family

ID=27419443

Family Applications (2)

Application Number Title Priority Date Filing Date
YU1203/86A YU45346B (en) 1985-07-09 1986-07-08 Process for obtaining pharmaceutical active 1-substituted oxindole-3-carboxamide
YU01144/87A YU114487A (en) 1985-07-09 1987-06-18 Process for obtaining pharmaceuticaly active 1-substituted oxindole-3-carboxamide

Family Applications After (1)

Application Number Title Priority Date Filing Date
YU01144/87A YU114487A (en) 1985-07-09 1987-06-18 Process for obtaining pharmaceuticaly active 1-substituted oxindole-3-carboxamide

Country Status (19)

Country Link
EP (1) EP0208510B1 (da)
JP (1) JPH0610193B2 (da)
CN (1) CN86105309A (da)
AT (1) ATE67185T1 (da)
AU (1) AU566065B2 (da)
CA (1) CA1286663C (da)
DE (1) DE3681358D1 (da)
DK (1) DK324286A (da)
ES (2) ES2001855A6 (da)
FI (1) FI862882A (da)
GR (1) GR861760B (da)
HU (2) HU198015A (da)
IE (1) IE58566B1 (da)
IL (1) IL79356A (da)
NO (1) NO862750L (da)
NZ (1) NZ216788A (da)
PH (1) PH22641A (da)
PT (1) PT82931B (da)
YU (2) YU45346B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE68593B1 (en) 1989-12-06 1996-06-26 Sanofi Sa Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
FR2655344B1 (fr) * 1989-12-06 1992-04-03 Sanofi Sa Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant.
WO1991009598A1 (en) * 1990-01-05 1991-07-11 Pfizer Inc. Azaoxindole derivatives
FR2677356B1 (fr) * 1991-06-05 1995-03-17 Sanofi Sa Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant.
JPH08288983A (ja) * 1995-04-17 1996-11-01 Tokyo Tsuuki:Kk リンガ回路
US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6306851B1 (en) 1999-05-04 2001-10-23 American Home Products Corporation Cyclocarbamate and cyclic amide derivatives
US6399593B1 (en) 1999-05-04 2002-06-04 Wyeth Cyclic regimens using cyclic urea and cyclic amide derivatives
US6444668B1 (en) 1999-05-04 2002-09-03 Wyeth Combination regimens using progesterone receptor modulators
US6329416B1 (en) 1999-05-04 2001-12-11 American Home Products Corporation Combination regimens using 3,3-substituted indoline derivatives
US6423699B1 (en) 1999-05-04 2002-07-23 American Home Products Corporation Combination therapies using benzimidazolones
US6339098B1 (en) 1999-05-04 2002-01-15 American Home Products Corporation 2,1-benzisothiazoline 2,2-dioxides
US6369056B1 (en) 1999-05-04 2002-04-09 American Home Products Corporation Cyclic urea and cyclic amide derivatives
US6380178B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Cyclic regimens using cyclocarbamate and cyclic amide derivatives
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6417214B1 (en) 1999-05-04 2002-07-09 Wyeth 3,3-substituted indoline derivatives
US6319912B1 (en) 1999-05-04 2001-11-20 American Home Products Corporation Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides
US6407101B1 (en) 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6380235B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Benzimidazolones and analogues
US6498154B1 (en) 1999-05-04 2002-12-24 Wyeth Cyclic regimens using quinazolinone and benzoxazine derivatives
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6462032B1 (en) 1999-05-04 2002-10-08 Wyeth Cyclic regimens utilizing indoline derivatives
US6358947B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Tetracyclic progesterone receptor modulator compounds and methods
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
WO2002006228A1 (fr) * 2000-07-19 2002-01-24 Ube Industries, Ltd. Procede de production de 5-fluorooxyindole et procede de production d'un produit intermediaire de celui-ci
JP2004529110A (ja) 2001-03-06 2004-09-24 アストラゼネカ アクチボラグ 脈管損傷活性を有するインドール誘導体
JP4770826B2 (ja) * 2007-11-22 2011-09-14 大日本印刷株式会社 ２−オキシインドール誘導体の製造法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3749731A (en) 1971-07-08 1973-07-31 Warner Lambert Co 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide
US3882236A (en) 1973-12-26 1975-05-06 Lilly Co Eli Pharmaceutical compositions containing substituted 2-oxo-indolines and the use thereof to treat anxiety and tension
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds

Also Published As

Publication number Publication date
ES2009227A6 (es) 1989-09-16
EP0208510A2 (en) 1987-01-14
NO862750L (no) 1987-01-12
JPS6226269A (ja) 1987-02-04
YU114487A (en) 1988-02-29
PT82931A (en) 1986-08-01
YU120386A (en) 1988-02-29
CN86105309A (zh) 1987-01-14
AU566065B2 (en) 1987-10-08
EP0208510A3 (en) 1988-03-02
IL79356A (en) 1990-03-19
DE3681358D1 (de) 1991-10-17
GR861760B (en) 1986-11-10
NO862750D0 (no) 1986-07-08
NZ216788A (en) 1988-10-28
JPH0610193B2 (ja) 1994-02-09
ATE67185T1 (de) 1991-09-15
CA1286663C (en) 1991-07-23
IE861833L (en) 1987-01-09
HU198015A (en) 1989-07-28
PT82931B (pt) 1989-01-30
EP0208510B1 (en) 1991-09-11
DK324286A (da) 1987-01-10
IE58566B1 (en) 1993-10-06
PH22641A (en) 1988-10-28
FI862882A (fi) 1987-01-10
IL79356A0 (en) 1986-10-31
FI862882A0 (fi) 1986-07-08
ES2001855A6 (es) 1988-07-01
HUT41386A (en) 1987-04-28
AU5984786A (en) 1987-04-09
DK324286D0 (da) 1986-07-08

Similar Documents

Publication Publication Date Title
YU45346B (en) Process for obtaining pharmaceutical active 1-substituted oxindole-3-carboxamide
EP0435321A3 (en) Novel a-nor-steroid-3-carboxylic acid derivatives
HUT43997A (en) Fungicides comprising acrylic acid amides as active substance and process for preparing the acrylic acid amides
HUT41418A (en) Process for producing pharmaceutical compositions containing anticoagulator polipeptides and process for producing the active agents
PL318595A1 (en) Derivatives of phenyloacetic acid, method of and intermediate products for obtaining them and agents containing such derivatives
AU2867089A (en) (cycloalkylamino)methylenebis(phosphonic acid) and medicines containing the same as an active ingredient
DK165406C (da) Substituerede n-(2,4,6-trimethoxyphenyl)-fedtsyreamider, fremgangsmaade til fremstilling deraf, farmaceutisk praeparat indeholdende disse forbindelser samt anvendelse af disse forbindelser til fremstilling af et farmaceutisk praeparat til inhibering af intestinal absorption af kolesterol
HUT41765A (en) Herbicide composition containing 5-amino-1-pyridyl-pyrazole derivatives and process for producing the active agents
HUT42464A (en) Fungicide composition containing heteroaryl-propyl-amine derivatives as active agents and process for producing the active agents
HUT45024A (en) Insecticides and acaricides containing as active substance 1-aryl-pirosole-derivatives and process for production of the active substance
GR3001523T3 (en) Substituted pyrimidine amides of oleic or linoleic acid as inhibitors of acyl-coa cholesterol acyltransferase
GR3004253T3 (da)
AU1413788A (en) Dihydropyridinamides process for their preparation, and their use in medicaments
PL238572A1 (en) Pesticide and method of manufacture of novel substituted diamides of hydroxymalonic acids
HUT37865A (en) Pesticide compositions containing derivatives of alkane-,alkene- or alkadiene-carboxylic acid amides as active substances and process for preparing the active substances
KR960015807B1 (en) Process for the preparation of purified bis(2-hydrozyethyl) ester of 2,60naphthalenedi carboxylic acid
ES8206486A1 (es) Procedimiento para la obtencion de esteres de acido n,n-di- metilo-o-(4,6-dihidro-2h-tieno(3,4-c)-pirazol-3-il)-carbami-co, asi como sus 5,oxidos y 5,5-dioxidos de efecto pesticida
ES2001665A6 (es) Procedimiento para preparar tripeptidos alquilados en n
IT1151532B (it) Procedimento per la preparazione di p. clorofenossiacetil-piperonilpiperazina