YU33800A - Postupak za dobijanje derivata tiazolidindiona - Google Patents

Postupak za dobijanje derivata tiazolidindiona

Info

Publication number
YU33800A
YU33800A YU33800A YU33800A YU33800A YU 33800 A YU33800 A YU 33800A YU 33800 A YU33800 A YU 33800A YU 33800 A YU33800 A YU 33800A YU 33800 A YU33800 A YU 33800A
Authority
YU
Yugoslavia
Prior art keywords
formula
pharmaceutically acceptable
substituted
compound
group
Prior art date
Application number
YU33800A
Other languages
English (en)
Inventor
Robert Gordon Giles
Norman John Lewis
John Kirby Quick
Original Assignee
Smithkline Beecham Plc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10821570&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU33800(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Plc. filed Critical Smithkline Beecham Plc.
Publication of YU33800A publication Critical patent/YU33800A/sh
Publication of RS49793B publication Critical patent/RS49793B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Postupak za dobivanje jedinjenja formule I ili njegovog tautomernog oblika ili njegove farmaceutski prihvatljive soli ili njegovog farmaceutski prihvatljivog solvata, gde A1 predstavlja supstituisanu ili nesupstituisanu aromaticnu heterociklicnu grupu; R1 predstavlja atom vodonika, alkil grupu, acil grupu, aralkil grupu, gde aril deo moze da bude supstituisan ili nesupstituisan, ili supstituisana ili nesupstituisana aril grupa; A2 predstavlja benzen prsten koji ima ukupno do pet supstituenata; i n predstavlja ceo broj u oblasti od 2 do 6, koji obuhvata kataliticku redukciju jedinjenja formule (II), gde A1, R1, A2 i n su kao sto je definisano u vezi formulom I, okarakterisan time sto redukciona reakcija se izvodi uz koriscenje pritiska vodonika iznad 20 psiga, i zatim, ako se zahteva gradjenje farmaceutski prihvatljive soli i/ili farmaceutski prihvatljivog solvata jedinjenja formule I.
YUP-338/00A 1997-11-04 1998-10-27 Postupak za dobijanje derivata tiazolidindiona RS49793B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9723295.3A GB9723295D0 (en) 1997-11-04 1997-11-04 Novel process

Publications (2)

Publication Number Publication Date
YU33800A true YU33800A (sh) 2002-10-18
RS49793B RS49793B (sr) 2008-06-05

Family

ID=10821570

Country Status (44)

Country Link
US (2) US20060106221A1 (sh)
EP (2) EP1028960B1 (sh)
JP (2) JP3723448B2 (sh)
KR (1) KR100602551B1 (sh)
CN (1) CN1160351C (sh)
AP (1) AP1519A (sh)
AR (1) AR016660A1 (sh)
AT (1) ATE238302T1 (sh)
AU (2) AU1559599A (sh)
BG (1) BG64559B1 (sh)
BR (1) BR9814622A (sh)
CA (1) CA2309461A1 (sh)
CO (1) CO5011075A1 (sh)
CZ (1) CZ297209B6 (sh)
DE (1) DE69813869T2 (sh)
DK (1) DK1028960T3 (sh)
DZ (1) DZ2637A1 (sh)
EA (1) EA002722B1 (sh)
EC (1) ECSP082712A (sh)
ES (1) ES2197519T3 (sh)
GB (1) GB9723295D0 (sh)
HK (2) HK1032046A1 (sh)
HR (1) HRP20000263B1 (sh)
HU (1) HU224547B1 (sh)
ID (1) ID24644A (sh)
IL (1) IL135898A (sh)
IN (1) IN192870B (sh)
MA (1) MA26560A1 (sh)
MY (1) MY118605A (sh)
NO (1) NO315557B1 (sh)
OA (1) OA11521A (sh)
PE (1) PE129399A1 (sh)
PL (1) PL192503B1 (sh)
PT (1) PT1028960E (sh)
RS (1) RS49793B (sh)
SA (1) SA98190820B1 (sh)
SI (1) SI1028960T1 (sh)
SK (1) SK285233B6 (sh)
TR (1) TR200001239T2 (sh)
TW (1) TW538037B (sh)
UA (1) UA56269C2 (sh)
UY (1) UY25227A1 (sh)
WO (1) WO1999023095A1 (sh)
ZA (1) ZA9810033B (sh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091359B2 (en) 1997-11-04 2006-08-15 Smithkline Beecham Plc Process for the preparation of thiazolidinedione derivatives
GB9723295D0 (en) 1997-11-04 1998-01-07 Smithkline Beecham Plc Novel process
HU225919B1 (en) * 1999-12-18 2007-12-28 Richter Gedeon Nyrt Thiazolidine-derivatives, process for their preparation pharmaceutical and intermediates
GB0023971D0 (en) * 2000-09-29 2000-11-15 Smithkline Beecham Plc Novel pharmaceutical
GB0023970D0 (en) * 2000-09-29 2000-11-15 Smithkline Beecham Plc Novel pharmaceutical
WO2003053367A2 (en) * 2001-12-20 2003-07-03 Teva Pharmaceutical Industries Ltd. Hydrogenation of precursors to thiazolidinedione antihyperglycemics
GB0307259D0 (en) * 2003-03-28 2003-05-07 Glaxo Group Ltd Process
GB2405403A (en) * 2003-08-29 2005-03-02 Cipla Ltd Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
AR047541A1 (es) * 2004-02-13 2006-01-25 Sandoz Ag Fosfato de 5-[[4-[2-metil-2-piridinil-amino-etoxi]fenil]metil]-2,4 tiazolidinadiona (rosiglitazona) y sus formas polimorficas
EP1745043A1 (en) * 2004-05-12 2007-01-24 Medichem S.A. Process for the preparation of rosiglitazone
CZ297266B6 (cs) * 2004-09-10 2006-10-11 Zentiva, A. S. Zpusob prípravy rosiglitazonu
CZ297347B6 (cs) * 2004-09-21 2006-11-15 Zentiva, A. S. Zpusob prípravy rosiglitazonu
CZ298424B6 (cs) * 2005-05-24 2007-09-26 Zentiva, A. S. Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
CN102727489A (zh) * 2012-07-18 2012-10-17 西南大学 5-芳(杂环)亚甲基噻唑烷-2，4-二酮在制备ppar激动剂中的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
CN1003445B (zh) * 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
US4812570A (en) 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
US5521201A (en) * 1987-09-04 1996-05-28 Beecham Group P.L.C. Method for treatment of atherosclerosis
US5232925A (en) * 1987-09-04 1993-08-03 Beecham Group P.L.C. Compounds
ATE186724T1 (de) * 1987-09-04 1999-12-15 Beecham Group Plc Substituierte thiazolidindionderivate
US5260445A (en) * 1987-09-04 1993-11-09 Beecham Group P.L.C. 2,4-thiazolidinediones
US5194443A (en) * 1987-09-04 1993-03-16 Beecham Group P.L.C. Compounds
US6288095B1 (en) * 1987-09-04 2001-09-11 Beecham Group P.L.C. Compounds
US20020049240A1 (en) * 1994-12-19 2002-04-25 Beecham Group P.1.C. Novel compounds
GB9023583D0 (en) * 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
GB9023585D0 (en) * 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
GB9124513D0 (en) * 1991-11-19 1992-01-08 Smithkline Beecham Plc Novel process
US6462337B1 (en) * 2000-04-20 2002-10-08 Agilent Technologies, Inc. Mass spectrometer electrospray ionization
AU3231093A (en) 1991-12-20 1993-07-28 Upjohn Company, The A reduction method for substituted 5-methylene-thiazolidinediones
GB9218830D0 (en) 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
US5741803A (en) * 1992-09-05 1998-04-21 Smithkline Beecham Plc Substituted thiazolidinedionle derivatives
US6632947B2 (en) * 1997-02-18 2003-10-14 Smithkline Beecham Plc Process for the preparation of substituted thiazolidinedione
UY24886A1 (es) 1997-02-18 2001-08-27 Smithkline Beecham Plc Tiazolidindiona
US7091359B2 (en) * 1997-11-04 2006-08-15 Smithkline Beecham Plc Process for the preparation of thiazolidinedione derivatives
GB9723295D0 (en) 1997-11-04 1998-01-07 Smithkline Beecham Plc Novel process

Also Published As

Publication number Publication date
CZ297209B6 (cs) 2006-10-11
KR100602551B1 (ko) 2006-07-19
HRP20000263B1 (en) 2009-01-31
JP2001521937A (ja) 2001-11-13
HK1048804A1 (zh) 2003-04-17
PT1028960E (pt) 2003-09-30
MY118605A (en) 2004-12-31
DE69813869T2 (de) 2004-01-29
WO1999023095A1 (en) 1999-05-14
AR016660A1 (es) 2001-07-25
ECSP082712A (es) 2008-08-29
MA26560A1 (fr) 2004-12-20
EP1028960B1 (en) 2003-04-23
NO20002174D0 (no) 2000-04-27
AU1559599A (en) 1999-05-24
DK1028960T3 (da) 2003-08-11
IL135898A (en) 2005-08-31
HUP0100144A3 (en) 2002-04-29
JP2004339235A (ja) 2004-12-02
AU2002300593B8 (en) 2006-05-04
RS49793B (sr) 2008-06-05
EP1028960A1 (en) 2000-08-23
EA002722B1 (ru) 2002-08-29
PE129399A1 (es) 2000-02-24
KR20010031720A (ko) 2001-04-16
GB9723295D0 (en) 1998-01-07
UA56269C2 (uk) 2003-05-15
EA200000484A1 (ru) 2000-10-30
CN1278818A (zh) 2001-01-03
SA98190820B1 (ar) 2006-10-29
DZ2637A1 (fr) 2003-03-08
ID24644A (id) 2000-07-27
ZA9810033B (en) 2000-05-03
BR9814622A (pt) 2000-10-03
HRP20000263A2 (en) 2000-12-31
US7351832B2 (en) 2008-04-01
BG64559B1 (bg) 2005-07-29
IN192870B (sh) 2004-05-22
AP1519A (en) 2005-12-20
NO20002174L (no) 2000-05-30
NO315557B1 (no) 2003-09-22
JP3723448B2 (ja) 2005-12-07
IL135898A0 (en) 2001-05-20
TW538037B (en) 2003-06-21
OA11521A (en) 2004-02-09
EP1219620A1 (en) 2002-07-03
CO5011075A1 (es) 2001-02-28
PL192503B1 (pl) 2006-10-31
SK285233B6 (sk) 2006-09-07
CA2309461A1 (en) 1999-05-14
HU224547B1 (hu) 2005-10-28
UY25227A1 (es) 1999-05-14
AU2002300593B2 (en) 2006-03-23
CN1160351C (zh) 2004-08-04
TR200001239T2 (tr) 2001-07-23
SI1028960T1 (en) 2003-10-31
CZ20001633A3 (cs) 2000-10-11
BG104505A (en) 2001-01-31
US20070066662A1 (en) 2007-03-22
ES2197519T3 (es) 2004-01-01
DE69813869D1 (de) 2003-05-28
HK1032046A1 (en) 2001-07-06
ATE238302T1 (de) 2003-05-15
HUP0100144A2 (hu) 2001-08-28
AP2000001808A0 (en) 2000-06-30
US20060106221A1 (en) 2006-05-18
PL340366A1 (en) 2001-01-29
SK6502000A3 (en) 2000-09-12

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