YU33003A - Formulacija rastvora za inhalaciju sa soli tiotropijuma - Google Patents

Formulacija rastvora za inhalaciju sa soli tiotropijuma

Info

Publication number
YU33003A
YU33003A YU33003A YUP33003A YU33003A YU 33003 A YU33003 A YU 33003A YU 33003 A YU33003 A YU 33003A YU P33003 A YUP33003 A YU P33003A YU 33003 A YU33003 A YU 33003A
Authority
YU
Yugoslavia
Prior art keywords
formulation containing
solution formulation
tiotropium salt
inhalative solution
inhalative
Prior art date
Application number
YU33003A
Other languages
English (en)
Inventor
Barbara Niklaus-Humke
Christel Schmelzer
Petra Barth
Karin Drechsel
Original Assignee
Boehringer Ingelheim Pharma Gmbh. & Co.Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh. & Co.Kg. filed Critical Boehringer Ingelheim Pharma Gmbh. & Co.Kg.
Priority to MEP-2008-404A priority Critical patent/ME00244B/me
Publication of YU33003A publication Critical patent/YU33003A/sh
Publication of RS50859B publication Critical patent/RS50859B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Predmetni pronalazak se odnosi na formulaciju za inhalaciju bez pogonskog gasa sa tiotropijum bromidom odn. tiotropijum bromid monohidratom koji je rastvoren u vodi ili u smeši vode i etanola i na aerosol za inhalaciju bez pogonskog gasa koji se dobija od nje.[The invention relates to a propellant-free inhalation formulation of tiotropium bromide or tiotropium bromide monohydrate, which is dissolved in water or in a mixture consisting of water and ethanol, and to propellant-free inhalable aerosols resulting therefrom.
YUP-330/03A 2000-10-31 2001-10-24 Formulacija rastvora za inhalaciju sa soli tiotropijuma RS50859B (sr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MEP-2008-404A ME00244B (me) 2000-10-31 2001-10-24 Formulacija rastvora za inhalaciju sa soli tiotropijma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10054036 2000-10-31

Publications (2)

Publication Number Publication Date
YU33003A true YU33003A (sh) 2006-05-25
RS50859B RS50859B (sr) 2010-08-31

Family

ID=7661723

Country Status (39)

Country Link
EP (2) EP1837021A3 (sh)
JP (1) JP4344135B2 (sh)
KR (1) KR100853107B1 (sh)
CN (2) CN101292964A (sh)
AR (1) AR038764A1 (sh)
AT (1) ATE373473T1 (sh)
AU (2) AU2173802A (sh)
BG (1) BG66315B1 (sh)
BR (1) BRPI0115076B8 (sh)
CA (1) CA2426074C (sh)
CY (1) CY1107825T1 (sh)
CZ (1) CZ300794B6 (sh)
DE (2) DE50113037D1 (sh)
DK (1) DK1333819T3 (sh)
EA (1) EA007604B1 (sh)
EC (1) ECSP034541A (sh)
EE (1) EE05314B1 (sh)
ES (1) ES2294045T3 (sh)
HK (1) HK1060524A1 (sh)
HR (1) HRP20030338B1 (sh)
HU (1) HU229411B1 (sh)
IL (2) IL155538A0 (sh)
ME (1) ME00244B (sh)
MX (1) MXPA03003742A (sh)
MY (1) MY138940A (sh)
NO (1) NO332519B1 (sh)
NZ (1) NZ526023A (sh)
PE (1) PE20030092A1 (sh)
PL (1) PL203316B1 (sh)
PT (1) PT1333819E (sh)
RS (1) RS50859B (sh)
SA (1) SA01220482B1 (sh)
SI (1) SI1333819T1 (sh)
SK (1) SK286027B6 (sh)
TW (1) TWI293885B (sh)
UA (1) UA78690C2 (sh)
UY (1) UY26989A1 (sh)
WO (1) WO2002036104A2 (sh)
ZA (1) ZA200302922B (sh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10216036A1 (de) * 2002-04-11 2003-10-23 Boehringer Ingelheim Pharma Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz
CN1292748C (zh) * 2003-03-05 2007-01-03 南昌弘益科技有限公司 噻托溴铵吸入粉雾剂及其制备工艺
JP5165245B2 (ja) * 2003-11-03 2013-03-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規なチオトロピウム塩、その製造方法及びチオトロピウム塩を含有する医薬組成物
PT1682541E (pt) * 2003-11-03 2010-04-14 Boehringer Ingelheim Int Processo para a preparação de sais de tiotrópio
CA2606549A1 (en) 2005-05-02 2006-11-09 Boehringer Ingelheim International Gmbh Crystalline forms of tiotropium bromide
EP2044967A1 (de) * 2007-10-01 2009-04-08 Boehringer Ingelheim Pharma GmbH & Co. KG Zerstäuber
CN104306361A (zh) * 2014-09-24 2015-01-28 万特制药(海南)有限公司 一种含噻托溴铵的吸入性溶液
CN111374963A (zh) * 2018-12-31 2020-07-07 天津药业研究院有限公司 一种用于吸入的噻托铵溶液剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (de) * 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
DE19536902A1 (de) * 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
DE19847968A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen

Also Published As

Publication number Publication date
NZ526023A (en) 2005-05-27
ECSP034541A (es) 2003-05-26
EE200300203A (et) 2003-10-15
CN1473038A (zh) 2004-02-04
EP1837021A3 (de) 2008-03-19
WO2002036104A2 (de) 2002-05-10
JP2004512357A (ja) 2004-04-22
BRPI0115076B8 (pt) 2021-05-25
KR100853107B1 (ko) 2008-08-21
EA200300482A1 (ru) 2003-12-25
JP4344135B2 (ja) 2009-10-14
DE10152521A1 (de) 2002-07-11
CZ300794B6 (cs) 2009-08-12
SA01220482B1 (ar) 2007-07-31
HK1060524A1 (en) 2004-08-13
PT1333819E (pt) 2007-10-29
HUP0301378A2 (hu) 2003-10-28
ES2294045T3 (es) 2008-04-01
CY1107825T1 (el) 2013-06-19
BG66315B1 (bg) 2013-04-30
PL203316B1 (pl) 2009-09-30
EA007604B1 (ru) 2006-12-29
BG107727A (bg) 2004-11-30
IL155538A0 (en) 2003-11-23
EP1837021A2 (de) 2007-09-26
CZ20031486A3 (cs) 2003-08-13
AU2173802A (en) 2002-05-15
IL155538A (en) 2008-11-26
AR038764A1 (es) 2005-01-26
EE05314B1 (et) 2010-08-16
PL360405A1 (en) 2004-09-06
RS50859B (sr) 2010-08-31
NO20031911D0 (no) 2003-04-29
HRP20030338B1 (en) 2011-09-30
DK1333819T3 (da) 2007-12-03
CN101292964A (zh) 2008-10-29
KR20030060926A (ko) 2003-07-16
UY26989A1 (es) 2002-06-20
CN100396285C (zh) 2008-06-25
UA78690C2 (uk) 2007-04-25
MY138940A (en) 2009-08-28
HUP0301378A3 (en) 2005-12-28
CA2426074A1 (en) 2002-05-10
MEP40408A (en) 2011-02-10
SK5272003A3 (en) 2003-10-07
AU2002221738B2 (en) 2007-01-11
NO20031911L (no) 2003-04-29
NO332519B1 (no) 2012-10-08
HRP20030338A2 (en) 2005-04-30
BRPI0115076B1 (pt) 2016-07-26
PE20030092A1 (es) 2003-03-24
ATE373473T1 (de) 2007-10-15
SI1333819T1 (sl) 2007-12-31
HU229411B1 (en) 2013-12-30
MXPA03003742A (es) 2004-10-15
EP1333819A2 (de) 2003-08-13
DE50113037D1 (de) 2007-10-31
WO2002036104A3 (de) 2002-08-01
CA2426074C (en) 2008-12-23
TWI293885B (en) 2008-03-01
EP1333819B1 (de) 2007-09-19
ME00244B (me) 2011-05-10
ZA200302922B (en) 2004-04-22
BR0115076A (pt) 2003-07-29
SK286027B6 (sk) 2008-01-07

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