YU171190A - Postupak za dobijanje 23-(c1-c6 alkiloksim) makrolidnih jedinjenja - Google Patents

Postupak za dobijanje 23-(c1-c6 alkiloksim) makrolidnih jedinjenja

Info

Publication number
YU171190A
YU171190A YU171190A YU171190A YU171190A YU 171190 A YU171190 A YU 171190A YU 171190 A YU171190 A YU 171190A YU 171190 A YU171190 A YU 171190A YU 171190 A YU171190 A YU 171190A
Authority
YU
Yugoslavia
Prior art keywords
preparation
alkyloxime
macrolide compounds
macrolide
compounds
Prior art date
Application number
YU171190A
Other languages
English (en)
Other versions
YU47520B (sh
Inventor
D.R. Maulding
A. Kumar
Original Assignee
American Cyanamid Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Company filed Critical American Cyanamid Company
Priority to SI9011711A priority Critical patent/SI9011711A/sl
Publication of YU171190A publication Critical patent/YU171190A/sh
Publication of YU47520B publication Critical patent/YU47520B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Liquid Crystal Substances (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Lubricants (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Opisan je postupak za dobijanje 23-(C1-C6alkiloksim)-makrolidnog jedinjenja pomoću oksidacije kristalnih 5-O-p-nitrobenzoil-makrolidnog jedinjenja.
YU171190A 1989-09-11 1990-09-10 Postupak za dobijanje 23-(c1-c6alkiloksim)-ll-f28249 jedinjenja YU47520B (sh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SI9011711A SI9011711A (sl) 1989-09-11 1990-09-10 Postopek za pridobivanje 23-(C1-C6 alkil-oksim)-LL-F28249 spojin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/405,793 US4988824A (en) 1989-09-11 1989-09-11 Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds

Publications (2)

Publication Number Publication Date
YU171190A true YU171190A (sh) 1992-07-20
YU47520B YU47520B (sh) 1995-10-03

Family

ID=23605260

Family Applications (1)

Application Number Title Priority Date Filing Date
YU171190A YU47520B (sh) 1989-09-11 1990-09-10 Postupak za dobijanje 23-(c1-c6alkiloksim)-ll-f28249 jedinjenja

Country Status (28)

Country Link
US (1) US4988824A (sh)
EP (1) EP0421081B1 (sh)
JP (1) JP2939312B2 (sh)
KR (1) KR0160977B1 (sh)
CN (1) CN1028428C (sh)
AT (1) ATE107650T1 (sh)
AU (1) AU634579B2 (sh)
BG (1) BG60620B1 (sh)
BR (1) BR9004493A (sh)
CA (1) CA2024919C (sh)
DE (1) DE69010129T2 (sh)
DK (1) DK0421081T3 (sh)
ES (1) ES2057291T3 (sh)
GE (1) GEP19981003B (sh)
HK (1) HK1000095A1 (sh)
HU (1) HU206721B (sh)
IE (1) IE66030B1 (sh)
IL (1) IL95303A (sh)
LV (1) LV10503B (sh)
MD (1) MD425C2 (sh)
NZ (1) NZ235151A (sh)
PL (1) PL165332B1 (sh)
PT (1) PT95242B (sh)
RU (1) RU2030416C1 (sh)
SI (1) SI9011711A (sh)
UA (1) UA26907C2 (sh)
YU (1) YU47520B (sh)
ZA (1) ZA907186B (sh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439924A (en) * 1991-12-23 1995-08-08 Virbac, Inc. Systemic control of parasites
AU660205B2 (en) 1991-12-23 1995-06-15 Virbac, Inc Systemic control of parasites
US5478951A (en) * 1994-06-22 1995-12-26 American Cyanamid Company Method for the purification of 23-E isomers of 23-imino derivatives of LL-F28249 compounds
AU695656B2 (en) 1995-02-24 1998-08-20 Novartis Tiergesundheit Ag Composition for controlling parasites
SI0750907T1 (en) * 1995-06-30 2002-08-31 American Cyanamid Company Stable macrolide and macrolide vaccine compositions
WO1999017760A2 (en) 1997-10-02 1999-04-15 Microcide Pharmaceuticals, Inc. Fungal or mammalian cell efflux pump inhibitors for enhancing susceptibility of the cell to a drug
US6762327B2 (en) * 2002-04-29 2004-07-13 Wyeth Selective oxidation process with enhanced safety
US7348417B2 (en) * 2003-08-07 2008-03-25 Wyeth Method of purifying moxidectin through crystallization
AU2006100658C4 (en) * 2006-05-08 2009-07-23 Wyeth Process
AU2006203459B2 (en) * 2006-05-08 2010-02-25 Wyeth Intermediates and processes using them
AU2006100660B4 (en) * 2006-06-22 2006-10-05 Wyeth Improved oxidation process with enhanced safety and use thereof
WO2013082373A1 (en) 2011-12-02 2013-06-06 Merial Limited Long-acting injectable moxidectin formulations and novel moxidectin crystal forms
CN104277050B (zh) * 2013-07-04 2016-05-04 北大方正集团有限公司 一种制备莫西克汀的方法
CN104017001B (zh) * 2014-06-18 2016-01-13 大连九信生物化工科技有限公司 一种化学合成莫西克汀的方法
CN104292239A (zh) * 2014-09-30 2015-01-21 大连九信生物化工科技有限公司 一种消除莫西克汀生产过程中副产物二甲基硫醚的方法
CN104628740B (zh) * 2015-02-13 2017-06-16 河北圣雪大成制药有限责任公司 一种化学合成及纯化莫西克汀的方法
CN104860961B (zh) * 2015-04-10 2017-08-04 新宇药业股份有限公司 一种制备5‑氧（对‑硝基苯甲酰）‑尼莫克汀的方法
CN106831811B (zh) * 2015-08-12 2018-10-26 内蒙古佳瑞米精细化工有限公司 一种制备高含量尼莫克汀的方法
CN114591347B (zh) * 2022-03-29 2023-03-24 河北美荷药业有限公司 莫西菌素中间体及制备方法、莫西菌素的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
IL78621A (en) * 1985-04-30 1991-06-30 American Cyanamid Co Mylbemycin analogs,their preparation and pesticidal compositions containing them
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
ATE109783T1 (de) * 1986-09-12 1994-08-15 American Cyanamid Co 23-oxo(keto) und 23-imino-derivate von ll-f28249- verbindungen.
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
US4855317A (en) * 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
GB8721376D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
PT90506B (pt) * 1988-05-10 1994-08-31 American Cyanamid Co Processo para a preparacao de compostos macrolidos
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
US4900758A (en) * 1989-05-11 1990-02-13 Ici Americas Inc. Novel insecticides
DE69023454T2 (de) * 1989-09-11 1996-06-05 American Cyanamid Co., Wayne, N.J. 13-Alkyl-23-Imino und 13-Halo-23-Imino-Derivate von LL-F28249-Verbindungen und ihre Verwendung als Endo- und Ectoparasitizide, Insektizide, Akarizide und Nematozide Mittel.

Also Published As

Publication number Publication date
US4988824A (en) 1991-01-29
CA2024919C (en) 2001-12-11
LV10503B (en) 1996-04-20
JPH03141283A (ja) 1991-06-17
RU2030416C1 (ru) 1995-03-10
DK0421081T3 (da) 1994-07-25
CN1051043A (zh) 1991-05-01
UA26907C2 (uk) 1999-12-29
JP2939312B2 (ja) 1999-08-25
ZA907186B (en) 1991-06-26
HU206721B (en) 1992-12-28
HUT55019A (en) 1991-04-29
GEP19981003B (en) 1998-10-27
HU905842D0 (en) 1991-03-28
EP0421081B1 (en) 1994-06-22
AU6236290A (en) 1991-03-14
EP0421081A1 (en) 1991-04-10
KR0160977B1 (ko) 1998-12-01
BG92810A (bg) 1993-12-24
PT95242B (pt) 1997-06-30
CA2024919A1 (en) 1991-03-12
HK1000095A1 (en) 1997-11-21
SI9011711A (sl) 1998-02-28
KR910006490A (ko) 1991-04-29
BG60620B1 (bg) 1995-10-31
DE69010129D1 (de) 1994-07-28
IE66030B1 (en) 1995-11-29
IL95303A0 (en) 1991-06-30
IE903273A1 (en) 1991-03-27
IL95303A (en) 1994-11-28
CN1028428C (zh) 1995-05-17
MD425C2 (ro) 1997-04-30
YU47520B (sh) 1995-10-03
PL286824A1 (en) 1991-08-12
DE69010129T2 (de) 1995-01-26
BR9004493A (pt) 1991-09-10
PL165332B1 (pl) 1994-12-30
ATE107650T1 (de) 1994-07-15
ES2057291T3 (es) 1994-10-16
AU634579B2 (en) 1993-02-25
LV10503A (lv) 1995-02-20
PT95242A (pt) 1991-05-22
NZ235151A (en) 1992-11-25

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